[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ureterolithiasis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ureterolithiasis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100593938","super-pulsed-thulium-fiber-laser-versus-holmiumyag-laser-in-retrograde-intrarenal-surgery-for-upper-ureteral-and-renal-stones-100593938",false,"NCT07012941","Super-Pulsed Thulium Fiber Laser Versus Holmium:YAG Laser in Retrograde Intrarenal Surgery for Upper Ureteral and Renal Stones","An Application of Super-pulsed TFL vs Ho:YAG Laser in Retrograde Intrarenal Surgery for Upper Ureter and Renal Stones: A Multi-center Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n1. 18 ≤ Age ≤ 75 years old, regardless of gender, able to tolerate surgery;\n2. Patients who have been confirmed by bilateral renal\u002Furinary tract CT to have upper ureteral or renal stones, single or multiple, and are planning to undergo ureteroscopic lithotripsy for stone removal;\n3. Confirmed by bilateral renal\u002Furinary tract CT, the cumulative maximum diameter of stones is 10mm\\\u003Ccumulative maximum diameter ≤ 25mm;\n4. Those who voluntarily participate and sign an informed consent form.\n\nExclusion Criteria:\n\n1. Uncontrollable systemic hemorrhagic disease;\n2. Severe spinal deformities, severe hip joint deformities, and difficulty in lithotomy position;\n3. Uncontrolled urinary tract infections;\n4. Any intracavitary surgery caused by anatomical factors of the urinary system cannot be performed;\n5. Pregnant, planned pregnancy within 3 months, and lactating female patients;\n6. The patients determined by the investigator to be unsuitable for this study include (but are not limited to): known to have human immunodeficiency virus (HIV) or AIDS; Suffering from mental illness; Infectious diseases;","ALL","18 Years","75 Years",{"count":20,"type":21},448,"ESTIMATED","INTERVENTIONAL",[24],"NA","The holmium laser is currently considered the gold standard for lithotripsy on urinary lithiasis, whereas the super-pulsed thulium fibre laser is a relatively new technology. Through a multi-center prospective randomised clinical study that mainly aims to explore the effectiveness and safety of a super-pulsed fibre thulium laser compared to a holmium laser in the treatment of upper ureteral and renal stones (10mm\\\u003Ccumulative maximum diameter ≤ 25mm) in retrograde intrarenal surgery. The research participants are assigned randomly to undergo retrograde intrarenal surgery (RIRS) either using a super-pulsed thulium fibre laser or a holmium-YAG laser with an allocation ratio of 1:1. The secondary aim of this study is to provide high-level evidence for the development of diagnostic and treatment guidelines in the field of urolithiasis, both domestically and internationally. The outcomes of the RIRS procedures are compared for the two treatment arms.",[27,28],"Ureterolithiasis","Renal Calculi",[30,31,32,33,34,35],"Super pulse thulium fiber laser (SPTFL)","Ho:YAG laser","Lithotripsy","Ureteral Stone","Ureteroscopy","renal stone","NOT_YET_RECRUITING","2025-06-09",{"date":39,"type":40},"2025-06-10","ACTUAL",{"date":42,"type":21},"2025-07-01",{"date":44,"type":21},"2027-03-20",{"name":46,"class":47},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":48},"100580762","an-intelligent-pressure-and-temperature-control-ureteral-soft-scope-system-for-treating-stones-with-infection-100580762","NCT06841523","An Intelligent Pressure and Temperature Control Ureteral Soft Scope System for Treating Stones With Infection.","Intelligent Pressure and Temperature Control Ureteral Soft Scope System for the Treatment of Upper Ureteral Stones Complicated With Infection in the Kidney and Upper Ureter: a Multicenter Randomized Controlled Clinical Study","Inclusion Criteria:\n\n1. 18 ≤ Age ≤ 75 years old, regardless of gender, able to tolerate surgery;\n2. ASA I-III;\n3. Patients who have been confirmed by bilateral renal\u002Furinary tract CT to have upper ureteral or renal stones, single or multiple, with a cumulative maximum diameter of 10mm \\\u003C cumulative maximum diameter ≤ 20mm, and are planning to undergo ureteroscopic lithotripsy for stone removal;\n4. Confirmed urinary tract infection, indicated by positive urine leukocytes and nitrite, or positive urine culture, with appropriate antibiotic treatment administered preoperatively;\n5. Those who voluntarily participate and sign an informed consent form.\n\nExclusion Criteria:\n\n1. Uncontrollable systemic hemorrhagic disease;\n2. Severe spinal deformities, severe hip joint deformities, and difficulty in lithotomy position;\n3. Uncontrolled acute urinary tract infections;\n4. Any intracavitary surgery caused by anatomical factors of the urinary system cannot be performed;\n5. Pregnant, planned pregnancy within 3 months, and lactating female patients;\n6. The patients determined by the investigator to be unsuitable for this study include (but are not limited to): known to have human immunodeficiency virus (HIV) or AIDS; Suffering from mental illness; Infectious diseases.",{"count":57,"type":21},288,[24],"The goal of this clinical trial is to determine the efficacy and safety of a novel intelligent pressure and temperature-controlled ureteroscope system for treating renal and upper ureteral stones with concurrent infection. It will also assess its ability to reduce postoperative complications and improve stone clearance rates. The main questions it aims to answer are:\n\nDoes the intelligent system lower the complication rate and enhance stone clearance compared to standard ureteroscopy? What safety issues or medical problems do participants experience when using the intelligent system? Researchers will compare the intelligent pressure and temperature-controlled ureteroscope system to a standard ureteroscope to evaluate its effectiveness in treating renal and upper ureteral stones.\n\nParticipants will:\n\nUndergo surgery using either the intelligent system or a standard ureteroscope Be monitored for postoperative complications, stone clearance, and other relevant outcomes Participate in follow-up visits to assess recovery and treatment efficacy",[27,28],[33,35,34,62],"Upper urinary tract stones with concurrent infection","2025-03-04",{"date":65,"type":40},"2025-03-07",{"date":67,"type":21},"2025-04-01",{"date":69,"type":21},"2028-04-01",{"name":46,"class":47}]