[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"urgency-frequency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:urgency-frequency":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100636290","low-energy-shock-wave-therapy-for-overactive-bladder-in-women-with-metabolic-syndrome-100636290",false,"NCT07563764","Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome","A Randomized, Double-Blind, Sham-Controlled Trial of Low-Energy Extracorporeal Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome","Inclusion:\n\n* Female participants aged 20 to 75 years\n* Diagnosed with overactive bladder (OAB), defined as urinary frequency (≥8 times\u002Fday), nocturia (≥2 times\u002Fnight), and urgency (≥2 episodes\u002Fweek) for at least 3 months\n* Diagnosed with metabolic syndrome, defined by the presence of at least three of the following criteria:\n* Waist circumference ≥80 cm\n* Blood pressure ≥130\u002F85 mmHg or receiving antihypertensive treatment\n* Fasting glucose ≥100 mg\u002FdL or receiving treatment for diabetes\n* Triglycerides ≥150 mg\u002FdL or receiving lipid-lowering treatment\n* High-density lipoprotein cholesterol \\\u003C50 mg\u002FdL\n* No pharmacological or injection treatment for OAB within 3 months prior to enrollment\n* Able to understand and comply with study procedures and questionnaires\n* Willing to provide informed consent\n\nExclusion:\n\n* History of kidney stones or bladder stones\n* Urinary tract infection within 3 months prior to enrollment or recurrent urinary tract infections (≥3 episodes)\n* Lower urinary tract surgery within 6 months prior to enrollment\n* Known or suspected malignancy of the urinary tract\n* Significant bladder outlet obstruction\n* Severe coagulopathy, liver failure, or renal failure\n* Prior pelvic malignancy or pelvic radiation therapy\n* Intravesical injection or electrical stimulation therapy within the past year\n* Substance abuse (drug or alcohol) within the past year\n* Chronic pelvic pain due to other causes\n* Inability to complete study questionnaires or procedures","FEMALE","20 Years","75 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Overactive bladder (OAB) is a common condition that causes urinary urgency, frequent urination, and nocturia, which can significantly affect quality of life. Women with metabolic syndrome may have a higher risk of OAB due to vascular and metabolic abnormalities.\n\nThis study aims to evaluate the effectiveness and safety of low-energy extracorporeal shock wave therapy (LiESWT), a non-invasive treatment, in women with metabolic syndrome-associated OAB. Participants will be randomly assigned to receive either active LiESWT treatment or a sham (inactive) procedure.\n\nSymptoms and treatment outcomes will be assessed using validated questionnaires, including the Overactive Bladder Symptom Score (OABSS), International Consultation on Incontinence Questionnaire (ICIQ-SF), Urinary Distress Inventory (UDI-6), and Incontinence Impact Questionnaire (IIQ-7), as well as a voiding diary and uroflow measurements.\n\nThe results of this study may help determine whether LiESWT is an effective treatment option for improving OAB symptoms in this patient population.",[27,28,29,30,31],"Bladder","Lower Urinary Track Symptoms","Metabolic Syndrome","Urgency-Frequency","Bladder, Overactive",[33,34,35,36,37,38,39,40],"Low-energy extracorporeal shock wave therapy","LiESWT","Overactive bladder","Metabolic syndrome","Urinary urgency","Urinary frequency","Nocturia","Randomized controlled trial","RECRUITING","2026-04-30",{"date":44,"type":45},"2026-05-04","ACTUAL",{"date":47,"type":45},"2025-02-10",{"date":49,"type":21},"2026-06-30",{"name":51,"class":52},"KMUHIRB-F(I)-20230051","OTHER"]