[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"urinary-retention-postoperative\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:urinary-retention-postoperative":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,40,65,94,119,154,180],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100606345","phase-4-uroselective-alpha-1-antagonist-to-reduce-the-incidence-and-duration-of-postoperative-urinary-retention-following-spine-surgery-100606345",false,"NCT07174349","Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery","The Use of an Uroselective Alpha-1-antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery","Inclusion Criteria:\n\n* Cervical Laminectomy\n* Cervical Posterior Fusion\n* Cervical Anterior\u002FPosterior Fusion\n* Lumbar Laminectomy\n* Lumbar Posterolateral Fusion\n* Lumbar Interbody Fusion\n\nExclusion Criteria:\n\n* Cervical Anterior Discectomy and Fusion\n* Cervical Anterior Corpectomy\n* Cervical Posterior Discectomy\n* Cervical Foraminotomy\n* Lumbar Discectomy (METRx or Open)\n* Lumbar Foraminotomy\n* Lumbar Anterior Fusion\n* Myelopathy with bladder dysfunction\n* Patients currently taking an alpha-antagonist\n\n  o The following drugs are alpha antagonists: alfuzosin, doxazosin, prazosin, terazosin, tamsulosin, and phenoxybenzamine.\n* Patients with history of allergy or sensitivity to tamsulosin or other alpha-antagonist\n* History of prostatectomy or urologic surgery involving the bladder or urethra\n* Severe liver disease or end-stage renal disease\n* Patients taking strong inhibitors of CYP3A4\n\n  o The following drugs are strong inhibitors of CYP3A4: ketoconazole, itraconazole, clarithromycin, ritonavir, indinavir\u002Fritonavir, lopinavir\u002Fritonavir, and conivaptan.\n* Mental disability or prisoner\n* Pregnancy (for anesthesia purposes)","ALL","35 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","The purpose of this research is to see if the use of tamsulosin can decrease both the incidence and duration of urinary retention, as well as hospital length of stay following spine surgery.",[26],"Urinary Retention Postoperative","RECRUITING","2026-06-25",{"date":30,"type":31},"2026-06-29","ACTUAL",{"date":33,"type":20},"2026-10-01",{"date":35,"type":20},"2028-12-31",{"name":37,"class":38},"Mayo Clinic","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":39},"100408353","phase-2-impact-of-tamsulosin-on-post-operative-urinary-retention-following-pelvic-reconstructive-surgery-100408353","NCT04597372","Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery","The Impact of Tamsulosin on Duration of Post-Operative Urinary Retention in Women Undergoing Pelvic Reconstructive Surgery- A Double Blind, Randomized, Placebo-Controlled Study","Inclusion Criteria:\n\n* 18 years or older\n* willing and able to provide informed consent\n* postoperative urinary retention as defined by a failed RGVT prior to hospital discharge\n* Ability to speak and read English\n* Tolerate pill ingestion\n\nExclusion Criteria:\n\n* allergy\u002Fintolerance to Tamsulosin or sulfa drugs\n* preoperative history of urinary retention as defined by preoperative post void residual of \\>150mL\n* current use of alpha antagonist medication for hypertension\n* severe dementia\n* end stage renal or liver disease\n* history of severe heart failure or major cardiovascular event in the last 6 months",true,"FEMALE","18 Years",{"count":51,"type":20},154,[53],"PHASE2","The objective of the study is to determine the effectiveness of postoperative Tamsulosin in reducing the duration of acute postoperative urinary retention (POUR) following pelvic reconstructive surgery through a double blind, randomized placebo-controlled trial.",[26],"2026-03-18",{"date":58,"type":31},"2026-03-20",{"date":60,"type":31},"2021-11-03",{"date":62,"type":20},"2026-12",{"name":64,"class":38},"Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":73,"enrollmentInfo":74,"targetDuration":76,"studyType":77,"phases":4,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":4},"100622145","rectus-abdominis-detrusor-myoplasty-for-urinary-retention-100622145","NCT07379814","Rectus Abdominis Detrusor Myoplasty for Urinary Retention","To Investigate the Outcomes of Rectus Abdominis Flap Detrusor Myoplasty for Urinary Retention","RADM","Inclusion Criteria:\n\n* Hypo- or acontractility of the bladder documented on urodynamic testing\n* Injury \\>1 year ago for spinal cord injury patients, no improvement in contractility with time\n* Failed sacral nerve stimulation implant for urinary retention treatment (If previously implanted)\n* Irreversible non-neurogenic bladder acontractility\u002Fhypocontractility (i.e myogenic failure after chronic obstruction, aging, frailty, idiopathic)\n* Undergoing RADM\n\nExclusion Criteria:\n\n* Documented bladder outlet obstruction\n* Spinal cord lesion above T12\n* Upper motor neuron lesion (i.e. multiple sclerosis, stroke)\n* Rectus diastasis, significant abdominal wall hernia, or other anatomic barrier to rectus flap harvest\n* Life expectancy \\\u003C10 years\n* Pregnant at time of surgery","75 Years",{"count":75,"type":20},50,"1 Year","OBSERVATIONAL","This investigates the outcomes of a surgical technique using the patient's own abdominal wall muscles to help contract the bladder in patients with urinary retention",[80,81,26],"Urinary Retention","Urinary Retention After Procedure",[83],"urinary retention","NOT_YET_RECRUITING","2026-01-23",{"date":87,"type":31},"2026-01-30",{"date":89,"type":20},"2026-05-01",{"date":91,"type":20},"2036-05-01",{"name":93,"class":38},"University Hospitals Cleveland Medical Center",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":47,"sex":16,"minAge":101,"maxAge":4,"enrollmentInfo":102,"targetDuration":4,"studyType":21,"phases":103,"briefSummary":105,"conditions":106,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":39},"100596807","phase-3-post-operative-urinary-retention-on-revision-knee-arthroplasty-the-role-of-intrathecal-morphine-100596807","NCT07050277","Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine","POURRKA","Inclusion Criteria:\n\n* Non pregnant patients undergoing unilateral non infected rTKA surgery;\n* Older than 21 years of age, with American Society of Anesthesiologists (ASA) physical status I-III;\n* With no alcohol or drug dependency history;\n* With sufficient understanding and co-operation about the usage of a perineural catheter for pain management; body mass index (BMI) under 45;\n* With no allergy to medications used in the study protocol (bupivacaine, lidocaine, ropivacaine, midazolam, propofol, ketamine, morphine, hydromorphone, fentanyl, acetaminophen, celecoxib, ondansetron, dexamethasone, tranexamic acid);\n* No current or recent use of opioids (within the last 2 weeks) in an average oral morphine equivalent (OME) of 20 mg\u002Fday or higher;\n* With no contra-indications for neuraxial anesthesia, IPACK block, ACB and adductor canal catheter insertion;\n* Who speak and understand the English language;\n* Who agrees to participate on this study through the signature of the consent form.\n\nExclusion Criteria:\n\n* Patients will be excluded of the study if they have a failed spinal anesthesia and needs for a conversion to general anesthesia;\n* If peripheral nerve blocks are not possible to be performed due to technical difficulties;\n* If during patient's care a deviation of the protocol occurs;\n* If CACB catheter has issues on its function, disconnects or exteriorizes within the first 48 hours of infusion;\n* Or if patient decides to withdraw from the study.","21 Years",{"count":75,"type":20},[104],"PHASE3","Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs. The multimodal approach, including single shot or continuous nerve blocks with catheters and spinal or epidural morphine, is a stablished strategy. Although the administration of intrathecal morphine (IM) has been shown to significantly reduce pain scores, it is not free of adverse effects. Postoperative urinary retention (POUR) is possible and might increase the risk of periprosthetic infection. The purpose of this study is to compare patients undergoing rTKAS under spinal anesthesia with IM to patients undergoing the same procedure, under the same anesthetic technique, but with no IM, for POUR and postoperative pain related outcomes. All patients will have single shot and continuous adductor canal block (CACB) and single shot IPACK (interspace between the popliteal artery and the posterior knee capsule) block. The hypothesis is that postoperative pain control is comparable between the groups, with lower incidence of POUR in patients with no IM given.",[107,108,26,109],"Arthroplasties, Knee Replacement","Nerve Block","Anesthesia, Spinal","2025-12-19",{"date":112,"type":31},"2025-12-29",{"date":114,"type":31},"2025-06-24",{"date":116,"type":20},"2027-08-01",{"name":118,"class":38},"University of Toronto",{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":125,"eligibilityCriteria":126,"healthyVolunteers":47,"sex":16,"minAge":49,"maxAge":127,"enrollmentInfo":128,"targetDuration":4,"studyType":21,"phases":130,"briefSummary":131,"conditions":132,"keywords":140,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":39},"100601981","phase-4-d-fab-pour-trial-dexmedetomidine-vs-fentanyl-as-adjuvants-to-bupivacaine-on-postoperative-urinary-retention-100601981","NCT07117565","D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention","Comparison of Intrathecal Dexmedetomidine Versus Intrathecal Fentanyl as Adjuvants to Bupivacaine on Post-Operative Urinary Retention in Lower Limb Surgery","D-FAB-POUR","Inclusion Criteria:\n\n* Adults aged 18 to 60 years\n* Scheduled for elective lower limb surgery under spinal anesthesia\n* Classified as American Society of Anesthesiologists (ASA) physical status II or III\n* Minimum height of 150 cm (to ensure uniform drug volume)\n* Able to understand the study procedures and provide written informed consent (in English or Nepali)\n\nExclusion Criteria:\n\n* Contraindications to spinal anesthesia (e.g., coagulopathy, infection at injection site, hemodynamic instability)\n* Known allergy or hypersensitivity to bupivacaine, fentanyl, or dexmedetomidine\n* Chronic pain conditions or long-term opioid use\n* Neurological, Cardiac, Renal, or uncontrolled diabetic conditions\n* Current treatment for prostatic pathology or use of alpha-2 blockers\n* Presence of a Foley's catheter preoperatively\n* Estimated surgical duration: \\>2.5 hours\n* Inability or unwillingness to provide informed consent","60 Years",{"count":129,"type":20},190,[23],"This study aims to compare two medications, dexmedetomidine and fentanyl, when used alongside a commonly used spinal anesthetic called bupivacaine in patients undergoing lower limb surgery. The main focus of the study is to see which combination causes fewer problems with urination after surgery - a condition known as postoperative urinary retention (POUR). POUR can lead to discomfort, delayed recovery, and a need for catheterization. Dexmedetomidine is a newer drug that may help reduce this problem compared to fentanyl, which is more commonly used but may increase the risk of urinary retention. This trial will help determine which medication combination provides better pain relief while reducing urinary side effects. The study is being conducted as a randomized, double-blind trial at a hospital in Nepal and will include 190 adult patients.\n\n\\-",[133,134,135,136,109,137,138,139,26],"Spinal Anesthesia","Postoperative Complications","Dexmedetomidine","Fentanyl","Bupivacaine","POUR","Orthopedic Surgery",[141,142,143,135,136,144],"Postoperative urinary retention","Spinal anesthesia","Intrathecal adjuvants","Perioperative complications","2025-08-09",{"date":147,"type":31},"2025-08-12",{"date":149,"type":20},"2025-09-15",{"date":151,"type":20},"2026-11-25",{"name":153,"class":38},"Tribhuvan University Teaching Hospital, Institute Of Medicine.",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":160,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":16,"minAge":162,"maxAge":4,"enrollmentInfo":163,"targetDuration":4,"studyType":21,"phases":165,"briefSummary":166,"conditions":167,"keywords":168,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":39},"100536224","phase-2-prevention-of-post-operative-urinary-retention-after-thoracic-surgery-trial-100536224","NCT06262048","Prevention of Post Operative Urinary Retention After Thoracic Surgery Trial","Prevention of Post Operative Urinary Retention After Thoracic Surgery: A Phase II Feasbility Trial","PrePOURTS","Inclusion Criteria ( 2 or more of the following risk factors):\n\n* Male Sex\n* Age greater than or equal to 40 years\n* History of Diabetes Mellitus\n* Prior pelvic irradiation\n* Use of indwelling Thoracic Epidural analgesia\n* Prior history of urinary retention\n\nAND\n\nInternational Prostate Specific Score greater than or equal to 1.\n\nExclusion Criteria:\n\n* Active treatment of Benign Prostatic Hyperplasia (BPH)\n* Hypersensitivity or allergy to tamsulosin HCL\n* Active treatment with tamsulosin or other alpha-blocker or uses of tamsulosin\u002F other alpha-blocker within 3 weeks of enrollment date\n* Active urinary tract infection\n* History of urological disorder specified as urethral stricture, BPH, bladder or prostate malignancy.\n* History of urological surgery (Transurethral resection of the Prostate, Transurethral resection of the Bladder, Bladder suspension, prostatectomy)\n* Underlying neurological disorders resulting in impaired bladder function\n* Any known contraindication to the use of tamsulosin HCL\n* Nursing\u002F Breastfeeding women\n* Use of intraoperative bladder catheter\n* patients for whom cataract and\u002For glaucoma surgery is scheduled.\n* patients on strong inhibitors of CYP3A4 (e.g., ketoconazole), on moderate inhibitors of CYP3A4 (e.g., erythromycin), on strong (e.g. paroxetine), on moderate (e.g., terbinafine) inhibitors of CYP2D6 or in patients known to be CYP2D6 poor metabolizers.\n* patients with a serious or life-threatening sulfa allergy\n* patients with severe hepatic insufficiency\n* patients with severe renal impairment (creatinine clearance of \\\u003C10 mL\u002Fmin)\n* patients with a serious or life-threatening sulfa allergy","40 Years",{"count":164,"type":20},60,[53],"The objectives of this study are to determine the feasibility of conducting a full-scale randomized control trial comparing the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention in people undergoing elective thoracic surgery.",[26],[83,169,170],"thoracic surgery","urinary catheter","2024-10-24",{"date":173,"type":31},"2024-10-28",{"date":175,"type":31},"2024-10-01",{"date":177,"type":20},"2026-02-01",{"name":179,"class":38},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's",{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":186,"eligibilityCriteria":187,"healthyVolunteers":47,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":188,"targetDuration":4,"studyType":21,"phases":190,"briefSummary":192,"conditions":193,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":39},"100416771","urinary-retention-after-arthroplasty-100416771","NCT04707001","Urinary Retention After Arthroplasty","Urinary Retention After Arthroplasty - UREA Trial","UREA","Inclusion Criteria:\n\n* elective total knee arthroplasty\n\nExclusion Criteria:\n\n* previous surgery for urologic cancer\n* fracture as indication for surgery\n* lack of co-operation\n* untreated urinary retention\n* nephrostoma\n* general anesthesia",{"count":189,"type":20},170,[191],"NA","Arthroplasty increases the risk of postoperative urinary retention. Treatment of postoperative urinary retention is indwelling or intermittent catheterization. The need for catheterization is most commonly determined with an ultrasound scanner. Catheterization increases the risk of urinary tract infection, which may further lead to haematogenic infection of the artificial joint. There is no evidence of an optimal way to monitor the onset of spontaneous urination.\n\nThe aim of the study is to determine whether monitoring the onset of spontaneous urination after fast track knee arthroplasty is safe based on symptoms alone without ultrasound monitoring.",[26,194],"Arthroplasty Complications","2024-02-12",{"date":197,"type":31},"2024-02-13",{"date":199,"type":31},"2021-05-01",{"date":201,"type":20},"2026-07",{"name":203,"class":38},"Central Finland Hospital District"]