[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"urinary-tract-infection-bacterial\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:urinary-tract-infection-bacterial":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100596382","phase-4-betadine-vs-sterile-water-for-periurethral-preparation-100596382",false,"NCT07044726","Betadine vs Sterile Water for Periurethral Preparation","Betadine vs Sterile Water for Periurethral Preparation Prior to Straight Catherization in the Clinic Setting: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18+\n* Patient undergoing in office straight catherization\n\nExclusion Criteria:\n\n* History of culture proven recurrent urinary tract infection (2 in any 6-month period or 3 in any 12-month period)\n* Urine Analysis with +Nitrites\n* Catherization for any reason in the last 4 weeks\n* History of Iodine allergy\n* Patients unable to speak English\n* Patient does not have the capacity to consent\n* 2-3rd trimester pregnancy",true,"FEMALE","18 Years",{"count":20,"type":21},148,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The purpose of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water (water that has been treated to remove bacteria and living organisms) vs Betadine also known as Povidone-Iodine (a medical grade cleaning solution) changes the rates of bacteria in the urine after a temporary catheter, or draining tube, is placed into the bladder. Chemical antiseptics, including Betadine, are the current standard of care. An additional goal of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water vs betadine changes the amount of discomfort or pain patients experience with placement of a temporary catheter, or draining tube, in the bladder.",[27,28],"Catherization","Urinary Tract Infection Bacterial",[30,31,27],"Betadine","Sterile Water","RECRUITING","2026-05-01",{"date":35,"type":36},"2026-05-04","ACTUAL",{"date":38,"type":36},"2025-06-30",{"date":40,"type":21},"2028-05-21",{"name":42,"class":43},"University of Louisville","OTHER",2,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100628616","relevance-of-the-urine-bacterial-culture-performed-before-transurethral-resection-of-the-bladder-for-post-operative-febrile-urinary-tract-infections-prevention-a-non-inferiority-randomized-controlled-trial-100628616","NCT07463963","Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial","RUPTURE","Inclusion Criteria:\n\n* Patient aged 18 or over\n* Scheduled for TURB surgery for a suspected or confirmed diagnosis of bladder tumor\n* Affiliated person or beneficiary of a social security scheme\n* Written informed consent obtained from the participant\n\nExclusion Criteria:\n\n* Patient with active UTI\n* Planned combined surgery\n* Patient previously included in this research protocol\n* People benefiting from enhanced protection, namely minors, people deprived of their liberty by judicial or administrative decision, people staying in a health or social institution, adults under legal protection\n* Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception (Combined (estrogen and progestogen containing) hormonal contraception associated with inhibition of ovulation : oral, intravaginal, transdermal; Progestogen-only hormonal contraception associated with inhibition of ovulation : oral, injectable, implantable; Intrauterine device; Intrauterine hormone-releasing system; Bilateral tubal occlusion) or permanent sterilization methods ( hysterectomy, bilateral salpingectomy, bilateral oophorectomy).","ALL",{"count":54,"type":21},2600,[56],"NA","The main objective of the study is to demonstrate that not performing a systematic UC before the TURB procedure is non-inferior to performing a systematic UC in terms of the incidence of febrile UTIs during the first 30 postoperative days",[59,60,28],"Bladder Cancer","Transurethral Resection of the Bladder",[62],"Urine Culture","NOT_YET_RECRUITING","2026-04-24",{"date":66,"type":36},"2026-04-30",{"date":68,"type":21},"2026-05-15",{"date":70,"type":21},"2030-08-15",{"name":72,"class":43},"Poitiers University Hospital",15,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100384904","phase-4-shortened-antibiotic-treatment-of-5-days-in-gram-negative-bacteremia-100384904","NCT04291768","Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia","Short Course Antibiotic Treatment of Gram-negative Bacteremia: A Multicenter, Randomized, Non-blinded, Non-inferiority Interventional Study","GNB5","Inclusion Criteria:\n\n* Age \\>18 years\n* Blood culture positive for Gram-negative bacteria\n* Evidence of urinary tract source of infection (positive urine culture or at least one clinical symptom compatible with urinary tract infection)\n* Antibiotic treatment with antimicrobial activity to Gram-negative bacteria administrated within 12 hours of first blood culture\n* Temperature \\\u003C37.8°C at randomization\n* Clinically stabile at randomization (systolic blood pressure \\> 90 mm Hg, heart rate \\\u003C100 beats\u002Fmin., respiratory rate \\\u003C24\u002Fminute, peripheral oxygen saturation \\> 90 %)\n* Oral and written informed consent\n\nExclusion Criteria:\n\n* Antibiotic treatment (\\>2 day) with antimicrobial activity to Gram-negative bacteria within 14 days of inclusion\n* Gram-negative bacteremia within 30 days of blood culture\n* Immunosuppression (Untreated HIV-infection, Neutropenia (absolute neutrophil count \\\u003C 1.0 x 109\u002Fl), Untreated terminal cancer, Receiving immunosuppressive agents (ATC-code L04A), Corticosteroid treatment (≥20 mg\u002Fday prednisone or the equivalent for \\>14 days) within the last 30 days, Chemotherapy within the last 30 days, Immunosuppressed after solid organ transplantation, Asplenia)\n* Polymicrobial growth in blood culture\n* Bacteremia with non-fermenting Gram-negative bacteria (Acinetobacter spp, Burkholderia spp, Pseudomonas spp), Brucella spp, or Fusobacterium spp\n* Failure to remove source of infection within 72 hours of first blood culture (e.g. change of catheter á demeure)\n* Pregnancy or breastfeeding",{"count":83,"type":21},380,[24],"GNB5 is an investigator-initiated multicentre non-inferiority randomized controlled trial which aims to assess the efficacy and safety of shortened antibiotic for patients hospitalized with a Gram negative bacteremia with a urinary tract source of infection (GNB).\n\nFive days after initiation of antimicrobial therapy for GNB, participants are randomized 1:1 to parallel treatment arms: 5 days (intervention) or minimum 7 days (control) of antibiotic treatment. The intervention group discontinues antibiotics at day 5 if clinically stable and afebrile. The control group receives antibiotics for a duration of 7 days or longer at the discretion of the treating physician.\n\nThe primary outcome is 90-day survival without clinical or microbiological failure to treatment, which will be tested with a non inferiority margin of 10%.",[87,28],"Gram-negative Bacteremia",[89,90,91,92],"Gram-negative bacteremia","Urinary tract infection","Shortened antibiotic treatment","Bacterial infection","2023-02-06",{"date":95,"type":36},"2023-02-08",{"date":97,"type":36},"2020-03-11",{"date":99,"type":21},"2026-10-01",{"name":101,"class":43},"Thomas Benfield",13]