[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"uterus-scar\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:uterus-scar":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100539771","impact-of-single--versus-double-layer-hysterotomy-closure-on-cesarean-niche-development-a-randomized-controlled-trial-100539771",false,"NCT06308172","Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial","Inclusion Criteria:\n\n* nulliparous\n* singleton\n* age 18-45\n* spontaneous pregnancy or autologous assisted fertilization\n* gestational age 38-40 weeks\n* elective C-section\n* informed consent\n\nExclusion Criteria:\n\n* coagulopathy\n* autoimmune diseases\n* gestational diabetes\n* anticoagulant therapy\n* immunosuppressive therapy\n* endometriosis\n* uterine fibromatosis\n* spontaneous labour\n* connective tissue diseases","FEMALE","18 Years",{"count":18,"type":19},150,"ESTIMATED","INTERVENTIONAL",[22],"NA","The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the hysterotomy. Our primary outcome aims to investigate whether there is a reduction in the median duration of intermenstrual spotting in patients belonging to the two respective closure groups",[25,26,27,28,29],"Cesarean Section; Dehiscence","Uterine Bleeding","Uterus; Scar","Uterus Abnormal","Cesarean Section Complications","RECRUITING","2024-03-06",{"date":33,"type":34},"2024-03-13","ACTUAL",{"date":36,"type":34},"2021-12-01",{"date":38,"type":19},"2026-12-01",{"name":40,"class":41},"Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico","OTHER"]