[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vaginitis-bacterial\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vaginitis-bacterial":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100521433","effect-of-lactobacillus-johnsonii-or-white-pomegranate-extract-on-the-vaginal-health-100521433",false,"NCT06069531","Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health","Effect of Oral Probiotic Heat-killed Lactobacillus Johnsonii TCI250 or White Pomegranate Extract on the Vaginal Flora","Inclusion Criteria:\n\n1. Females aged 20-45\n2. Nugent score ≥ 4\n3. Menstrual cycle of 28-60 days\n\nExclusion Criteria:\n\n1. Pregnant or lactating women\n2. Antibiotic usage\n3. Other reproductive-related inflammatory diseases (e.g., candidiasis, gonorrhea, chlamydia infection)\n4. Allergy to probiotics or White Pomegranate-related components","FEMALE","20 Years","45 Years",{"count":20,"type":21},150,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are:\n\n* Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating female vaginal bacteria and improving vaginal health.\n* Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating inflammation.\n\nParticipants will be randomly assigned to placebo (n = 50), probiotic heat-killed Lactobacillus johnsonii TCI250 group (n = 50) and white pomegranate extract group (n = 50) for 8 weeks. Researchers will compare the vaginal flora and inflammation.",[27,28],"Vaginitis Bacterial","Inflammation, Ear",[30,31,32,33,34],"Bacterial Vaginitis","Probiotics","white pomegranate extract","Inflammation","Vaginal flora","RECRUITING","2025-05-12",{"date":38,"type":39},"2025-05-14","ACTUAL",{"date":41,"type":39},"2022-04-04",{"date":43,"type":21},"2025-12-31",{"name":45,"class":46},"Chung Shan Medical University","OTHER"]