[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"varicose-veins-leg\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:varicose-veins-leg":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100622936","phase-4-calcium-dobesilate-after-radiofrequency-ablation-for-varicose-veins-100622936",false,"NCT07390097","Calcium Dobesilate After Radiofrequency Ablation for Varicose Veins","Effect of Perioperative Calcium Dobesilate on Postprocedural Pain, Symptom Relief, and Quality of Life After Radiofrequency Ablation for Great Saphenous Vein Insufficiency: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18-70 years\n* Symptomatic primary varicose veins (CEAP classification C2-C4)\n* Great saphenous vein insufficiency confirmed by duplex ultrasound (reflux \\>0.5 seconds)\n* Great saphenous vein diameter 5-12 mm\n* Scheduled for radiofrequency ablation\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* History of deep vein thrombosis\n* Peripheral arterial disease (ABI \\\u003C0.9)\n* Active venous ulcer (CEAP C6)\n* Pregnancy or breastfeeding\n* Severe renal or hepatic insufficiency\n* Known allergy to calcium dobesilate\n* Use of venoactive drugs within the past 4 weeks\n* Current anticoagulant therapy\n* Previous venous intervention on the same limb\n* Bilateral disease requiring simultaneous treatment\n* Inability to comply with follow-up schedule","ALL","18 Years","70 Years",{"count":20,"type":21},250,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","This study evaluates whether calcium dobesilate, a venoactive drug, improves recovery after radiofrequency ablation (RFA) for varicose veins. Patients with great saphenous vein insufficiency undergoing RFA will be randomly assigned to receive either calcium dobesilate (500 mg twice daily) or standard care alone. The treatment starts 7 days before the procedure and continues for 30 days after. The primary outcome is postoperative pain at day 7. Secondary outcomes include pain at days 14 and 30, quality of life, ecchymosis, and return to daily activities.",[27,28,29],"Varicose Veins Leg","Great Saphenous Vein Insufficiency","Chronic Venous Insufficiency",[31,32,33,34,35],"Calcium Dobesilate","Radiofrequency Ablation","Venoactive Drug","Postoperative Pain","Quality of Life","NOT_YET_RECRUITING","2026-01-28",{"date":39,"type":40},"2026-02-05","ACTUAL",{"date":42,"type":21},"2026-02-28",{"date":44,"type":21},"2026-11",{"name":46,"class":47},"Oguz Arslanturk","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":48},"100618623","study-to-find-out-the-timing-for-the-optimal-imaging-of-varicose-veins-using-infrared-thermography-100618623","NCT07334028","Study to Find Out the Timing for the Optimal Imaging of Varicose Veins Using Infrared Thermography.","Observational Study to Ascertain the Optimum Time to Observe the Infra-red Image of Varicose Veins in the Lower Limb When Standing From a Supine Position.","Inclusion Criteria:\n\n* Patients undergoing venous duplex ultrasound scan for suspected varicose veins (primary or recurrent).\n* Able to stand still for 5 minutes.\n* Able to get on to and off of the surgical couch unaided.\n* Patient giving consent.\n\nExclusion Criteria:\n\n* Refusing consent.\n* Unable to get on a couch or stand unaided.\n* Unable to stand still for 5 minutes.",{"count":57,"type":21},20,"OBSERVATIONAL","The goal of this observational study is to identify the optimal time of Infrared imaging of varicose veins when patients move from a lying to a standing position.\n\nThe primary purpose is to enable us to improve our imaging of varicose veins in patients presenting with primary or recurrent leg varicose veins.\n\nThe main questions it aims to answer are:\n\nOutcome measure 1- How long after standing up from lying supine do leg varicose veins show up best on infrared imaging? Outcome measure 2 - Is there any difference in this timing between varicose veins arising from different sources in the leg?\n\nPatients will be asked to stand, and sequential infrared images will be taken every 5 seconds for 3 minutes.",[27],[62,63],"varicose vein","infrared imaging","RECRUITING","2026-01-05",{"date":67,"type":40},"2026-01-12",{"date":69,"type":40},"2025-09-26",{"date":71,"type":21},"2026-09-26",{"name":73,"class":47},"The Whiteley Clinic",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100563194","phase-4-intravenous-tramadol-and-magnesium-sulphate-for-prevention-of-shivering-100563194","NCT06612996","Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering","Comparative Study Between Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering Post Intrathecal Anesthesia a Randomized Clinical Study","Inclusion Criteria:\n\n\\- American Society of Anesthesiologists (ASA) I and II physical status undergoing an elective surgery under spinal anesthesia.\n\nExclusion Criteria:\n\n* history of uncontrolled comorbidities, cardiac, respiratory, renal or hepatic disease, patients who had allergy to any medication in the study, contraindications to spinal anesthesia (coagulation disorder, infection at site of puncture, raised intracranial tension or any spine deformity), fever \\>38 Celsius or less than 36 Celsius, body mass index more than 35 and who has history of alcohol intake","21 Years","60 Years",{"count":84,"type":21},180,[24],"The aim of this work was to compare the efficacy of intravenous (IV) tramadol versus magnesium sulphate added to 100 ml saline for prevention of shivering associated with spinal anesthesia.",[88,27,89],"Lower Extremity Chronic Venous Ulcers","Hernia",[91,92,93],"Tramadol","Magnesium Sulphate","Shivering","2024-09-23",{"date":96,"type":40},"2024-09-25",{"date":98,"type":21},"2024-10-10",{"date":100,"type":21},"2025-01-10",{"name":102,"class":47},"Al-Azhar University"]