[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vascular-aneurysm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vascular-aneurysm":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100410901","osa-as-a-remote-ischemic-preconditioning-in-vascular-surgery-100410901",false,"NCT04630535","OSA as a Remote Ischemic Preconditioning in Vascular Surgery","Obstructive Sleep Apnea as a Remote Ischemic Preconditioning in Patients Scheduled for Aorto-bifemoral Bypass Surgery","Inclusion Criteria:\n\n* patients scheduled for elective aorto-bifemoral bypass (AAA and Leriche syndrome patients)\n\nExclusion Criteria:\n\n* emergent surgery\n* aorto-bifemoral bypass using deep vein graft\n* re-operations\n* known OSA with CPAP treatment","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","Ischemia and reperfusion (I\u002FR) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure. Remote ischemic preconditioning (short periods of ischemia in anticipation of longer period of ischemia) may act protectively against ischemia.\n\nStudies of ischemic preconditioning in patients with AAA are conflicting. Obstructive sleep apnea (OSA) is a sleep disordered breathing syndrome which may have a protective effect against ischemia.\n\nThe investigators hypothesize that I\u002FR injury will be less pronounced in patients who have OSA and that the extent of I\u002FR injury will inversely correlate with OSA severity. Accordingly, the aim of this study is to compare postoperative complications and markers of I\u002FR in patients undergoing elective AAA repair who do and do not have OSA.",[24,25,26],"Obstructive Sleep Apnea","Vascular Aneurysm","Ischemia Reperfusion Injury",[28],"remote preconditioning","RECRUITING","2026-04-22",{"date":32,"type":33},"2026-04-27","ACTUAL",{"date":35,"type":33},"2020-11-01",{"date":37,"type":20},"2029-01-31",{"name":39,"class":40},"St. Anne's University Hospital Brno, Czech Republic","OTHER"]