[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vascular-diseaseperipheral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vascular-diseaseperipheral":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,38,69,93],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100635860","spectator-perfusion-monitoring-before-during-and-after-lower-extremity-revascularization-with-laser-speckle-contrast-imaging-100635860",false,"NCT07558174","SPECTATOR: Perfusion Monitoring Before, During and After Lower Extremity Revascularization With Laser Speckle Contrast Imaging","SPECTATOR","Inclusion Criteria:\n\n* Scheduled for lower-extremity revascularization\n* Undergoing pre- and postoperative indocyanine near-infrared fluorescence perfusion measurements\n\nExclusion Criteria:\n\nAny condition that the investigator considers to be potentially jeopardizing the patient's wellbeing or the study objectives","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the feasibility of Laser Speckle Contrast Imaging for perioperative perfusion assessment of the lower extremity before, during, and after revascularization.",[24],"Vascular Disease，Peripheral","RECRUITING","2026-05-04",{"date":28,"type":29},"2026-05-08","ACTUAL",{"date":31,"type":20},"2026-05",{"date":33,"type":20},"2028-06",{"name":35,"class":36},"Leiden University Medical Center","OTHER",1,{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":45,"enrollmentInfo":46,"targetDuration":4,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":37},"100596501","clinical-outcomes-safety-and-cost-effectiveness-analysis-of-two-catheters-xianrui-da-and-medtronic-in-radiofrequency-ablation-for-varicose-veins-100596501","NCT07046286","Clinical Outcomes, Safety, and Cost-Effectiveness Analysis of Two Catheters (Xianrui Da and Medtronic) in Radiofrequency Ablation for Varicose Veins","Clinical Outcomes, Safety, and Cost-Effectiveness Analysis of Two Catheters (Xianrui and Medtronic) in Radiofrequency Ablation for Varicose Veins","Inclusion Criteria:\n\n1. Age between 18 and 80 years old.\n2. Clinically diagnosed with primary lower extremity varicose veins, with CEAP grade C2 - C5, and requiring treatment of the great saphenous vein segment.\n3. Doppler ultrasound confirms that the reflux time of the saphenofemoral vein valve is \\> 1.0 second.\n4. Doppler ultrasound confirms that the diameter of the great saphenous vein in the supine position is \\> 3mm and \\\u003C 12mm.\n5. Only one limb of each patient is included in the study.\n6. The patient signs the informed consent form and is willing to cooperate with the examinations and follow - ups specified in the protocol.\n\nExclusion Criteria:\n\n1. Thrombosis in the great saphenous vein, or combined with deep vein thrombosis, or a history of deep vein thrombosis or pulmonary embolism.\n2. Recurrent varicose veins after previous treatment.\n3. Severe tortuosity of the great saphenous vein, with the expectation that the catheter cannot pass through.\n4. Severe lower extremity ischemia (CLI).\n5. Known allergy to drugs or device materials involved in the study.\n6. History of cardiac pacemaker or defibrillator implantation.\n7. Pregnant or breastfeeding women.\n8. Currently participating in other drug or device studies.\n9. Deemed unsuitable for endovenous treatment by the researcher.","80 Years",{"count":47,"type":20},200,"INTERVENTIONAL",[50],"NA","This study aims to systematically compare the clinical efficacy (venous closure rate and symptom relief rate), safety (perioperative and postoperative complications), and cost-effectiveness (direct medical costs) of domestic Xianruida radiofrequency catheter and imported Medtronic catheter in endovenous radiofrequency ablation for varicose veins through a single-center, prospective, non-inferiority randomized controlled trial.",[53,54,24],"Varicose Veins of Lower Limb","Venous Insufficiency of Leg",[56,57,58],"varicose veins of the great saphenous veins","radiofrequency ablation","catheters","NOT_YET_RECRUITING","2025-06-29",{"date":62,"type":29},"2025-07-01",{"date":64,"type":20},"2025-08-01",{"date":66,"type":20},"2026-10-01",{"name":68,"class":36},"Chengdu University of Traditional Chinese Medicine",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":48,"phases":79,"briefSummary":80,"conditions":81,"keywords":82,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":37},"100570736","comparative-analysis-of-radiofrequency-ablation-and-microwave-ablation-procedures-for-the-treatment-of-small-saphenous-varicose-veins-100570736","NCT06711120","Comparative Analysis of Radiofrequency Ablation and Microwave Ablation Procedures for the Treatment of Small Saphenous Varicose Veins","Randomized Controlled Study of Radio Frequency and Microwave of the Small Saphenous Vein","Inclusion Criteria:\n\n* Age ≥18 years and ≤90 years;\n* Clinical diagnosis of primary varicose veins of the lower extremities, CEAP clinical classification C2-C6, requiring treatment of the great and\u002For small saphenous vein segments, and at least 1 of the clinical symptoms of swelling, pain, burning sensation, heaviness, easy fatigue, itchy skin, and night cramps;\n* Valve insufficiency of the great saphenous vein, small saphenous vein, or transport vein;\n* Doppler ultrasound confirmation of a saphenous vein diameter greater than 3 mm and less than 12 mm in the standing position;\n* Only one limb per patient was selected for inclusion in the study;\n* Patients signed an informed consent form and were willing to co-operate in completing the protocol-specified investigations and follow-up visits.\n\nExclusion Criteria:\n\n* Thrombosis of the great saphenous or small saphenous vein, or combined deep vein thrombosis, or previous history of deep vein thrombosis or pulmonary embolism.\n* Recurrent varicose veins after previous treatment.\n* Severe distortion of the great saphenous vein with anticipated catheter failure.\n* Severe lower limb ischaemia (CLI) (ABPI \\\u003C0.8).\n* Known allergy to medications and device materials involved in the study.\n* Pre-existing implanted pacemaker, defibrillator, currently on regular anticoagulation therapy (e.g., warfarin, heparin).\n* Women who are pregnant or breastfeeding.\n* Unable or unwilling to complete the questionnaire.\n* Participating in a study of another drug or device.\n* Life expectancy \\\u003C1 year.\n* Those undergoing treatment for skin malignancies other than non-melanoma.\n* Daily use of narcotic drugs or non-steroidal anti-inflammatory drugs to control pain due to venous disease.\n* In the judgement of the investigator, endovenous therapy is not appropriate.","90 Years",{"count":78,"type":20},150,[50],"Objective: To investigate the clinical efficacy of ultrasound-guided radiofrequency ablation and microwave ablation in the treatment of primary saphenous varicose veins.",[53,54,24],[83,57,84],"varicose veins of the small saphenous veins","microwave ablation","2024-11-28",{"date":87,"type":29},"2024-12-02",{"date":89,"type":20},"2024-12-01",{"date":91,"type":20},"2025-12-01",{"name":68,"class":36},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":76,"enrollmentInfo":99,"targetDuration":101,"studyType":21,"phases":4,"briefSummary":102,"conditions":103,"keywords":104,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":113,"leadSponsor":114,"locationsCount":37},"100569361","observation-of-pain-during-the-treatment-of-great-saphenous-vein-using-microwave-ablation-and-analysis-of-related-factors-100569361","NCT06693245","Observation of Pain During the Treatment of Great Saphenous Vein Using Microwave Ablation， and Analysis of Related Factors","Inclusion Criteria:\n\n1. Age≥ 18 years old, ≤ 90 years old;\n2. the patient's life expectancy is greater than 12 months;\n3. The clinical diagnosis is primary VVs, CEAP classification C2-C6, and the GSV segment needs to be treated, including pain, burning sensation, heaviness, fatigue, itchy skin, night cramps and other clinical symptoms;\n4. Doppler ultrasound confirmed that the diameter of GSV was greater than 3mm and less than 12mm when standing;\n5. Doppler ultrasound confirms that GSV is located in the saphenofascia or the distance between GSV and the skin surface is \\>1cm;\n6. endovenous microwave ablation treatment only for unilateral GSV walking area;\n7. The patient is willing to cooperate with the completion of the examination specified in the protocol.\n\nExclusion Criteria:\n\n1. GSV thrombosis, or combined with deep vein thrombosis, or previous history of deep vein thrombosis and pulmonary embolism;\n2. patients with recurrence after prior VVs-related surgery (C2r);\n3. the GSV trunk is severely distorted, and it is expected that the catheter will not be able to pass;\n4. Severe ischemia of the lower limbs, Ankle brachial pressure index (ABPI) \\\u003C 0.8;\n5. Known allergy to the drugs and device materials involved in the study;\n6. Previously implanted with a pacemaker or defibrillator, and currently receiving regular anticoagulation therapy (such as warfarin, heparin);\n7. Pregnant or lactating females;\n8. Patients who are unable or unwilling to participate in the study;\n9. Participating in the research of other drugs or devices;\n10. Skin malignancies other than non-melanoma that are being treated;\n11. daily use of narcotic drugs or non-steroidal anti-inflammatory drugs to control pain caused by venous disease;\n12. The investigator judged that endovenous treatment was not suitable;",{"count":100,"type":20},155,"1 Day","Objective: This study is a single-center prospective observational research that recorded patients' pain scores at four time points during surgery (puncture and catheter insertion, swelling fluid injection, microwave generator operation, and end of surgery). It analyzed the correlation between pain during microwave ablation treatment for great saphenous vein varicosities and factors such as age, gender, body mass index, volume of swelling fluid used, and others, in order to summarize and improve surgical details to reduce patients' intraoperative pain.",[24,54,53],[105,106,107,108],"Varicose veins of the lower extremities","Endovenous Microwave Ablation","intraoperative pain","visual analogue scale of pain","2024-11-15",{"date":111,"type":29},"2024-11-18",{"date":89,"type":20},{"date":91,"type":20},{"name":68,"class":36}]