[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vasogenic-cerebral-edema\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vasogenic-cerebral-edema":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":34,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":45,"locationsCount":5},"100593973","a-prospective-evaluation-of-clinical-outcomes-in-acute-ischemic-stroke-after-endovascular-treatment-wdoppler-100593973",false,"NCT07013396","A Prospective Evaluation of Clinical Outcomes in Acute Ischemic Stroke After Endovascular Treatment w\u002FDoppler","A Prospective Evaluation of Clinical Outcomes in Acute Ischemic Stroke After Endovascular Treatment Using Transcranial","Inclusion Criteria:\n\n* Anterior circulation stroke including ACA, MCA or ICA stroke that underwent EVT including tandem occlusions.\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* Difficulty in detecting the acoustic window by TCD\n* Pregnancy\n* Incarcerated patients","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","Endovascular therapy (EVT) has proven to be more beneficial for patients with AIS caused by large vessel occlusions (LVO) than medical management alone. A recent meta-analysis of 5 RCTs showed that EVT significantly reduced disability at 90 days compared to medical management \\[1\\]. Despite its obvious benefits, patients may have neurological deterioration despite successful thrombectomy due to ischemia progression, intracranial hemorrhage, re-occlusion, or vasogenic edema. The incidence of early neurological deterioration (END) following EVT for acute stroke has been reported to be ranging from 14.1-35.2% with some studies defining END up to 7 days and some restricting the definition between 6-72 hours post thrombectomy. A small proportion of these patients, approximately 5.9-10.5%, experienced sICH following EVT. Whether END occurs due to ischemic or hemorrhagic it leads to worse outcomes.",[26,27,28,29,30,31,32,33],"Anterior Cerebral Artery Syndrome","Anterior Cerebral Artery Stroke","Acute Ischemic Stroke","Coronary Artery Disease","Cardioembolic Stroke","Congestive Heart Failure","Diabetes","Vasogenic Cerebral Edema",[35,36],"systolic blood pressure","Transcranial Doppler","NOT_YET_RECRUITING","2025-11-21",{"date":40,"type":41},"2025-11-25","ACTUAL",{"date":43,"type":20},"2027-02",{"date":43,"type":20},{"name":46,"class":47},"Virginia Commonwealth University","OTHER"]