[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ventilated-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ventilated-patients":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100616635","nasal-airflow-to-modulate-dyspnea-in-tracheostomized-patients-100616635",false,"NCT07308171","Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients","MODUS","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Tracheostomy and mechanical ventilation\n3. Dyspnea ≥3\n4. Consent to participate\n5. Affiliation to health insurance\n\nExclusion Criteria:\n\n1. Agitation, delirium\n2. Continuous use of sedatives\n3. Patients under law protection\n4. Inmates\n5. Patients without health insurance\n6. Breastfeeding and pregnancy","ALL","18 Years",{"count":19,"type":20},24,"ESTIMATED","INTERVENTIONAL",[23],"NA","The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.",[26],"Ventilated Patients",[28,29,30],"Mechanical ventilation","Tracheostomy","Nasal stimulation","NOT_YET_RECRUITING","2026-01-27",{"date":34,"type":35},"2026-01-29","ACTUAL",{"date":37,"type":20},"2026-02",{"date":39,"type":20},"2027-02",{"name":41,"class":42},"Assistance Publique - Hôpitaux de Paris","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100618215","critical-illness-after-hematopoietic-cell-transplantation-100618215","NCT07328724","Critical Illness After Hematopoietic Cell Transplantation","Critical Illness Among Recipients of Hematopoietic Cell Transplantation (CARE-HCT): a Prospective, Multicenter Observational Study in China","CARE-HCT","Inclusion Criteria:\n\n* Patients who underwent hematopoietic cell transplantation at any of the participating medical centers.\n* Patients who are admitted to ICU for the management of critical illness following hematopoietic cell transplantation.\n\nExclusion Criteria:\n\n* Admitted to ICU for a reason other than critical illness (e.g., routine postoperative monitoring) and discharged within 2 days of ICU admission.\n* Unavailable in-ICU clinical outcomes or absent key baseline characteristics.\n* Any other conditions that, in the opinion of the investigator, can interfere with the interpretation of data.",{"count":52,"type":20},4000,"OBSERVATIONAL","This is a prospective, multicenter observational trial for patients who develop critical illness after hematopoietic cell transplantation. Patients who are admitted to the intensive care unit after undergoing hematopoietic cell transplantation at the participating medical centers will be enrolled in this study. The clinical characteristics, laboratory profiles, managements, and clinical outcomes will be prospectively collected.",[56,26,57,58],"Critical Illness","Hematopoetic Stem Cell Transplantation","Transplant Complication",[60,61,62,63,64],"hematopoietic cell transplantation","critical illness","management","prognosis","transplant complication","2025-12-27",{"date":67,"type":35},"2026-01-09",{"date":69,"type":20},"2026-01-01",{"date":71,"type":20},"2036-12-31",{"name":73,"class":42},"Peking University People's Hospital",6,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":84,"conditions":85,"keywords":97,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":107},"100566342","study-of-sleep-quality-in-the-intensive-care-unit-and-association-with-weaning-from-invasive-ventilation-in-patients-with-chronic-obstructive-bronchopneumopathy-100566342","NCT06653933","Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy.","SLEECOP","Inclusion Criteria:\n\n* Patients diagnosed with COPD according to the GOLD criteria.\n* Mechanical ventilation by endotracheal tube and mechanical ventilation for \\> 24 hours.\n* Withdrawal of treatment with continuous sedation and\u002For neuroleptics.\n* Adequate recovery with Glasgow Coma Scale ≥ 8.\n\nExclusion Criteria:\n\n* Patients with central nervous system damage or neuromuscular pathology.\n* Pregnant or postpartum patients.\n* Patients or their relatives who object to participating in the study.",{"count":83,"type":20},42,"Patients admitted in ICU may require invasive mechanical ventilation, using a mechanical ventilator and an endotracheal tube.\n\nIn ICU, a prolonged duration of invasive mechanical ventilation may be responsible for ventilator-induced lung injury, pulmonary infection, prolonged administration of sedation, neuromyopathy and prolonged length of stay. The goal of the ICU healthcare teams is therefore to reduce the duration of invasive mechanical ventilation as much as possible.\n\nICU patients have many sleep disturbances: sleep fragmentation, sleep stage changes, changes in sleep architecture. These sleep disturbances are due to sedation and analgesia, delirium, patient care activities, noise and altered day-night cycles.\n\nChronic obstructive pulmonary disease (COPD) is a common respiratory disease. COPD complicates the management of invasive mechanical ventilation, particularly weaning of this invasive mechanical ventilation and extubation (removal of the intubation tube).\n\nTo reduce the risk of reintubation, it is recommended that a weaning test is performed prior to extubation. The purpose of this test is to simulate the conditions of breathing without the help of a ventilator after extubation. If the weaning test is successful, the patient can theoretically be extubated.\n\nThere are several causes associated with extubation failure, but studies suggest that sleep deprivation or poor sleep quality in the nights before extubation is one of them. In addition, patients with COPD often have chronic sleep disturbances or induced by their stay in the ICU (asthenia, bed rest, anxiety, sedation, etc.).\n\nThe aim of our study will be to compare the sleep characteristics of COPD patients with a failed weaning test and those with a successful test. Our hypothesis is that patients with a failed weaning test will have more sleep disturbances in the period of 72 hours before the weaning test.",[86,87,26,88,89,90,91,92,93,94,95,96],"COPD","COPD Exacerbation","Ventilator-Associated Pneumonia (VAP)","Ventilator Weaning","Weaning of Mechanical Ventilation","Sleep Quality","Sleep Disorders, Circadian Rhythm","Sleep Disorders","Failure, Respiratory","ICU Hospitalization","ICU Sedation",[86,91,90],"2024-10-21",{"date":100,"type":35},"2024-10-23",{"date":102,"type":20},"2025-01-01",{"date":104,"type":20},"2027-07-01",{"name":106,"class":42},"University Hospital, Grenoble",1]