[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ventral-incisional-hernia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ventral-incisional-hernia":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100604098","the-impact-study-personalized-physical-therapy-for-better-recovery-and-a-stronger-core-after-hernia-surgery-100604098",false,"NCT07145099","The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery","The IMPACT Study: A Randomized Controlled Trial of Individualized Management Post Ventral Hernia Repair (VHR) Utilizing Abdominal Core Therapy for Enhanced Recovery and Health Outcomes","IMPACT","Inclusion Criteria:\n\n* Participants must be aged 18-75.\n* Diagnosed clinically or via objective testing by a surgeon with a ventral transverse hernia \\>4 cm and \\\u003C10 cm.\n* Scheduled for elective surgical correction of a non-recurrent, primary or incisional ventral hernia.\n* Independent functional status.\n\nExclusion Criteria:\n\n* Individuals currently receiving or who have received PT within the last 30 days.\n* Individuals currently using an assistive device for ambulation.\n* Individuals diagnosed with a neurologic disorder will be excluded.\n* History of or plan for Botox injection or muscle release related to the hernia.\n* Pregnancy","ALL","18 Years","75 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to evaluate the efficacy, safety, and cost-effectiveness of a tailored physical therapy (PT) intervention targeting Abdominal Core Health components in patients recovering from ventral hernia repair. The study focuses on patients aged 18-75 diagnosed with a ventral transverse hernia between 4 cm and 10 cm, scheduled for elective Ventral Hernia Repair (VHR).\n\nThe main questions it aims to answer are:\n\n* Will tailored PT significantly improve abdominal core strength, biomechanical stability, and functional mobility compared to usual care at 3-months post-surgery?\n* Will tailored PT lead to higher patient-reported quality of life and satisfaction scores, with a lower incidence of post-operative complications such as bowel obstruction and pelvic floor dysfunction over a 1-year follow-up?\n* Will tailored PT result in decreased healthcare utilization, leading to overall cost savings or neutrality compared to usual care over the first year after VHR?\n\nResearchers will compare the tailored physical therapy group to a usual care group to see if the tailored intervention leads to significant improvements in clinical efficacy, patient outcomes, and cost-effectiveness.\n\nParticipants will:\n\n* Be randomly assigned to either the Usual Care Group or the PT Group.\n* If in the Usual Care Group, receive standard post-operative instructions for 12 weeks, including guidance on binder use, safe lifting, and gradual return to activities.\n* If in the PT Group, receive foundational post-operative instructions for the first 2 weeks (similar to usual care). Undergo 6 structured and individualized PT sessions over 10 weeks if in the PT Group, with progression based on Oswestry Disability Index (ODI) and Pelvic Floor Distress Inventory-20 (PFDI-20) scores, including Symptom Modulation, Movement Control, Functional Optimization, or Impairment-Based interventions.\n\nParticipants undergo data collection at 2 weeks, 12 weeks, and 1 year post-operation, including imaging, functional mobility tests, pain scales, patient-reported outcomes, physical measurements, and tracking of complications and healthcare utilization. Participate in semi-structured interviews after the 12-week assessment to provide qualitative insights into their experiences and perceived barriers\u002Ffacilitators.",[28,29,30],"Ventral Hernia","Ventral Incisional Hernia","Post Operative Pain",[32,33,34],"Physical Therapy","Rehabilitation","Economic Impact","NOT_YET_RECRUITING","2025-09-02",{"date":38,"type":39},"2025-09-10","ACTUAL",{"date":41,"type":22},"2026-01-01",{"date":43,"type":22},"2028-01-01",{"name":45,"class":46},"Thomas Jefferson University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100483446","robotic-versus-open-comparison-in-the-surgical-treatment-of-wide-abdominal-wall-hernias-rocstar-100483446","NCT05575141","Robotic Versus Open Comparison in the Surgical Treatment of Wide Abdominal Wall heRnias (ROCSTAR)","Robotic Versus Open Comparison in the Surgical Treatment of Wide Abdominal Wall Hernias: a Multicenter International Randomized Controlled Trial","ROCSTAR","Inclusion Criteria:\n\n\\- All patients requiring treatment of a wide ventral incisional hernia (of more than 8 centimetres in width)\n\nExclusion Criteria:\n\n* Pregnant or suspected pregnancy\n* Not-curatively treated malignancy, with life expectancy less than 24 months\n* Patients unable to give informed consent or complete study specific questionnaires\n* Emergency surgery\n* Primary ventral hernia repair\n* Exclusively lateral hernias not involving the midline\n* Incisional hernia repair after open abdomen or enterocutaneous fistula\n* Active wound infection\n* Previous anterior or posterior component separation\n* Patients with an existing ostomy\n* Patients with a life expectancy of less than 24 months\n* Patients suspected of being unable to comply with the study protocol",{"count":21,"type":22},[25],"In the treatment of ventral incisional hernias, a mesh repair in the retromuscular plane is considered as the gold standard. To allow for adequate medialization of the fascial borders and a complete closure of the defect in case of large incisional hernias, component separation techniques are increasingly being used. When compared to anterior component separation, posterior component separation by transversus abdominis release (TAR) seems to decrease postoperative wound problems. While laparoscopic techniques pose significant difficulties to perform TAR minimally invasively (mainly due to ergonomic and technical reasons), these limitations seem to be overcome by robotic platforms. Initial retrospective patient series report on significantly shorter postoperative hospital stay and fewer complications after robotic transversus abdominis release (rTAR), when compared to open transversus abdominis release (oTAR). High-quality prospective evidence on rTAR is currently lacking.",[29,60],"Abdominal Wall Hernia",[60,62,63,64],"robotic TAR (rTAR)","open TAR (oTAR)","transversus abdominis release (TAR)","2025-04-10",{"date":67,"type":39},"2025-04-11",{"date":69,"type":22},"2025-07-01",{"date":71,"type":22},"2033-01-01",{"name":73,"class":46},"Algemeen Ziekenhuis Maria Middelares",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":23,"phases":85,"briefSummary":86,"conditions":87,"keywords":88,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":4},"100530212","only-mesh-fixation-with-glue-of-ventralincisional-laparoscopic-hernia-repair-100530212","NCT06183840","Only Mesh Fixation With Glue of Ventral\u002FIncisional Laparoscopic Hernia Repair","OMEGA Trial: A Multicenter Randomized Controlled Non-inferiority Trial of Only MEsh Fixation With a Glue Applicator Comparing Traumatic vs Atraumatic Fixation of the Mesh in Ventral\u002FIncisional Laparoscopic Repair","OMEGA","Inclusion Criteria:\n\n* All adults with a BMI lesser than 35 Kg\u002Fm2 undergoing an elective laparoscopic primary ventral or incisional hernia repair with a fascial transverse defect between 4-8 cm (W2 EHS) on anterior or lateral location (M1-M5 up to 10 cm of length or L1-3)\n* ASA grade from I-II\n* Informed consent signed\n\nExclusion Criteria:\n\n* Patients less than 18 years and over 80 years of age.\n* Fascial transverse defect less than 4 cm and more than 8 cm.\n* Recurrent ventral or incisional hernia in the same place\n* Emergency surgery\n* Procedure involving concomitant surgeries (e.g. gastrointestinal, biliary or genitourinary surgery)\n* BMI greater than 35 Kg\u002Fm2\n* ASA III-IV\n* Pregnancy\n* Tobacco","80 Years",{"count":84,"type":22},250,[25],"This multicenter randomized controlled non-inferiority trial of only mesh fixation with a glue applicator is a trial to evaluate the outcomes between atraumatic laparoscopic mesh fixation with GLUTACK-Glubran2® and conventional traumatic fixation, so the primary endpoint of the study is to analyze the recurrence on ventral or incisional hernia repair 2 years postoperatively assessed by a clinical and\u002For imaging technique.",[29],[89,90,91,92,93,94],"Ventral hernia","Incisional hernia","Mesh","Glue","Tackers","IPOM plus","2024-03-04",{"date":97,"type":39},"2024-03-06",{"date":99,"type":22},"2024-03-10",{"date":101,"type":22},"2026-12-31",{"name":103,"class":104},"Institut Catala de Salut","OTHER_GOV"]