[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ventricular-tachycardia-pulseless\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ventricular-tachycardia-pulseless":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100349185","phase-4-epinephrine-dose-optimal-versus-standard-evaluation-trial-100349185",false,"NCT03826524","Epinephrine Dose: Optimal Versus Standard Evaluation Trial","CanROC Epinephrine Dose: Optimal Versus Standard Evaluation Trial (CanROC EpiDOSE Trial)","EpiDOSE","Inclusion Criteria:\n\n* Out-of-hospital cardiac arrest treated by paramedics\n* Initial recorded cardiac rhythm of VF or pulseless VT, or, AED shock on first analysis administered or witnessed by EMS (paramedic or fire)\n* Established intravenous vascular access\n\nExclusion Criteria:\n\n* Known or apparent age \\\u003C18 years\n* Initial recorded cardiac rhythm of VF or pulseless VT, or, AED shock on first analysis administered or confirmed by paramedics\n* Cardiac arrest due to an obvious non-cardiac primary cause (e.g. blunt or penetrating trauma, exsanguination, burns, drug overdose, drowning, anaphylaxis, sudden asphyxiation, etc.)\n* Administration of intramuscular, endotracheal tube, or intraosseous epinephrine\n* Prisoners or persons in police custody\n* Known allergy or sensitivity to epinephrine","ALL","18 Years",{"count":20,"type":21},3790,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The objective of this randomized controlled trial is to evaluate the effectiveness of a low cumulative dose of epinephrine compared to a standard cumulative dose of epinephrine during resuscitation from ventricular fibrillation (VF) or ventricular tachycardia (VT) in adult out-of-hospital cardiac arrest (OHCA) patients.",[27,28,29,30],"Cardiac Arrest, Out-Of-Hospital","Sudden Cardiac Arrest","Ventricular Fibrillation","Ventricular Tachycardia-Pulseless",[32,33,34,35],"out-of-hospital cardiac arrest","sudden cardiac arrest","epinephrine","randomized controlled trial","RECRUITING","2025-12-09",{"date":39,"type":40},"2025-12-11","ACTUAL",{"date":42,"type":40},"2023-05-24",{"date":44,"type":21},"2028-12",{"name":46,"class":47},"Unity Health Toronto","OTHER",8]