[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vestibular-hypofunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vestibular-hypofunction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,52,78,106,135,161,188,212],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100622179","visual-influences-on-vestibular-adaptation-100622179",false,"NCT07380256","Visual Influences on Vestibular Adaptation","Effects of Impaired Visual Acuity and Binocular Control Abnormalities (VABC) on Vestibulo-ocular Reflex (VOR) Adaptation in Adults With and Without Vestibular Hypofunction","Inclusion Criteria:\n\nFor All Participants (All Groups)\n\n* Age 18 to 60 years\n* Able to provide informed consent\n\nGroup-Specific Inclusion Criteria:\n\n* Group 1: Abnormal Uncorrected Static Visual Acuity (No Vestibular Hypofunction) Normal peripheral vestibular function\n* Group 2: Abnormal Uncorrected Static Visual Acuity + peripheral Vestibular Hypofunction\n* Group 3: Binocular Vision Abnormalities (No Vestibular Hypofunction) Normal peripheral vestibular function\n* Group 4: Binocular Vision Abnormalities + peripheral Vestibular Hypofunction\n\nIndividuals who have abnormal static visual acuity, a binocular vision abnormality (ocular misalignment, convergence insufficiency), and vestibular loss will be assigned to Group 4.\n\nThe following definitions will be used when determining group placement:\n\n* Abnormal Static Visual Acuity: Uncorrected visual acuity (head is still) ≥0.30 logMAR in both eyes.\n* Unilateral Vestibular Hypofunction: 60 ms VOR gain \\\u003C0.80 unilaterally for the lateral semicircular canal.\n* Bilateral Vestibular Hypofunction: 60 ms VOR gain \\\u003C0.80 bilaterally for the lateral semicircular canals.\n* Normal Vestibular Function: 60 ms VOR gain of 0.80 to 1.20 bilaterally for the lateral semicircular canals.\n* Convergence Insufficiency: ≥6 cm near point of convergence.\n* Ocular Misalignment: ≥4 prism diopters of manifest deviation of the eyes (tropia) on cover\u002Funcover testing.\n\nExclusion Criteria:\n\n* Diagnosis of fluctuating vestibular disorders (e.g., benign paroxysmal positional vertigo)\n* Neurologic conditions (e.g., multiple sclerosis), dementia,\n* Alcohol or drug abuse,\n* A major psychiatric disorder (e.g., schizophrenia),\n* Pain that limits cervical spine range of motion by \\>50% or that results in an -altered gait pattern.","ALL","18 Years","60 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this study is to learn whether a balance-training exercise called incremental vestibulo-ocular reflex adaptation (IVA) is safe and effective for adults with vision impairments, with or without additional vestibular (inner-ear balance) problems.\n\nThe main questions it aims to answer are:\n\n* Does IVA cause only mild, temporary symptoms and no serious adverse events?\n* Does IVA improve eye-movement reflexes, balance, and walking, and do these improvements differ between people with vision problems alone and those with both vision and vestibular impairments?\n\nResearchers will compare adults with vision impairment only to adults who have both vision and vestibular impairments to see whether the groups respond differently to IVA.\n\nParticipants will:\n\n* Complete symptom ratings before and after IVA\n* Undergo tests of vestibular reflexes (e.g., VOR gain)\n* Complete balance and walking assessments",[27,28,29],"Vestibular Hypofunction","Binocular Vision Abnormalities","Reduced Vision",[31,32,33,34,35,36,37,38],"vestibulo-ocular reflex","incremental vestibulo-ocular reflex adaptation","abnormal uncorrected static visual acuity","Gait Disorientation Test","video head impulse test","vertical and torsional alignment nulling","dynamic visual acuity test","modified Clinical Test of Sensory Interaction in Balance","RECRUITING","2026-04-14",{"date":42,"type":43},"2026-04-17","ACTUAL",{"date":45,"type":43},"2026-02-04",{"date":47,"type":21},"2029-12",{"name":49,"class":50},"Emory University","OTHER",2,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":16,"minAge":17,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":51},"100612434","vibrotactile-balance-belt-effect-on-improving-gait-100612434","NCT07253532","Vibrotactile Balance Belt Effect on Improving Gait","Impact of Vibrotactile Stimulation Via BalanceBelt and IMU-based Gait Analysis in Individuals With Balance Disorders","BalanceBelt","Inclusion Criteria:\n\n* Age 18-80 years old\n* Waist between 60 and 120 cm\n* Intact vibration sensitivity around the waist\n* Balance disorder and\u002For a diagnosis of ataxia or vestibular dysfunction (diagnosis based on imaging, clinical and family history, vestibular function tests, and\u002For genetic testing)\n* Speak English\n\nExclusion Criteria:\n\n* Previous Vestibular Rehabilitation Therapy (VRT) finished less than 2 months ago\n* Inability to stand or walk slowly without support in the light on a firm underground\n* Neurological, ophthalmological and\u002For orthopedic disorders that hampers vestibular, oculomotor or gait and posture examination",true,"80 Years",{"count":63,"type":21},90,[24],"This study will examine the effect of using a vibrotactile feedback implemented into a belt, at improving gait in those with gait disorders.",[27,67,68],"Ataxia - Other","Gait Impairment","2026-03-23",{"date":71,"type":43},"2026-03-27",{"date":73,"type":43},"2026-03-20",{"date":75,"type":21},"2030-12-01",{"name":77,"class":50},"Johns Hopkins University",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":60,"sex":16,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":105},"100572374","subthreshold-vestibular-stimulation-as-a-strategy-for-rehabilitation-100572374","NCT06732440","Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation","Inclusion Criteria for Bilateral Vestibular Hypofunction:\n\n1\\. Bilateral lateral canal VOR gain of \\\u003C 0.8 on video head impulse testing OR bilateral positive bedside head impulse test\n\nInclusion Criteria for Unilateral Vestibular Hypofunction:\n\n1\\. Unilateral yaw aVOR gain of \\\u003C 0.8 on video head impulse testing OR unilateral positive bedside head impulse test\n\nInclusion Criteria for all Participants:\n\n1. Must be able to stand for 5 minutes unassisted\n2. No leg or foot amputations\n3. No lower limb braces\n4. Not currently pregnant by self-report\n5. Weight \\\u003C= 300 pounds (due to limitations of testing equipment)\n\nExclusion Criteria for all participants:\n\n1. Severe head trauma or traumatic brain injury\n2. History of seizures\n3. Alternative neurologic illness or condition known to impact vestibular or balance function (e.g., stroke, neurodegenerative disorders, demyelinating illness)\n4. Major psychiatric (e.g., panic disorder, psychosis, etc.) disorder\n5. Any of the following eye diseases or conditions: amblyopia (or \"lazy eye\") or history of amblyopia, diagnosis of age- related macular degeneration, retina dystrophy, glaucoma, cataracts,\n6. Recent (\\\u003C6 months) orthopedic injury that may affect test performance\n7. Recent surgery (\\\u003C 6 months) that may impact test performance.\n8. Other severe health problems (heart disease, pulmonary disease, cancer, etc.) that may affect test performance\n9. Due to potentially nauseogenic nature of some motions and to protect fetus and mother, pregnant women will also be excluded from this study\n\n   * Since the investigators cannot address every possible potential individual recruit in advance, additional exclusion criteria may be required.","19 Years","89 Years",{"count":87,"type":21},48,[24],"The nervous system responds to changes in external or internal conditions by altering the behavior of neurons through multiple forms of neural plasticity. A specific form of plasticity, \"homeostatic plasticity\", stabilizes neural activity by driving the excitability of neurons toward a \"set-point\" level of activity. Over the last six years, new data have come to light showing that the vestibular system also possess a robust capacity to modulate sensitivity to self-motion cues in response to prolonged periods of motion. Collectively, these studies have demonstrated a capacity to use motion perturbations (i.e., low, or high levels of vestibular stimulation) to dynamically adjust the sensitivity of the vestibular system on both the single neuron and behavioral levels. The ability to use subthreshold motion stimuli to drive plasticity in the vestibular system motivates this study. The investigators aim to determine the impact of subthreshold motion on (a) balance performance and (b) balance training in individuals with peripheral vestibular hypofunction.",[27,91,92,93],"Bilateral Vestibular Hypofunction","Presbyvestibulopathy","Healthy Controls",[91,95],"Vestibular Rehabilitation","2026-03-16",{"date":98,"type":43},"2026-03-17",{"date":100,"type":43},"2026-02-09",{"date":102,"type":21},"2026-12-31",{"name":104,"class":50},"Creighton University",1,{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":16,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":120,"overallStatus":125,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":4},"100627747","optimizing-cochlear-implant-laterality-in-patients-with-unilateral-vestibular-weakness-100627747","NCT07452653","Optimizing Cochlear Implant Laterality in Patients With Unilateral Vestibular Weakness","Inclusion Criteria:\n\n* Patients over the age of 50 years\n* Bilateral and symmetric moderate to profound sensorineural hearing loss (SNHL). Symmetric SNHL will be defined objectively as no more than 20dB difference at any 2 consecutive frequencies or no more than 15dB difference at any 3 consecutive frequencies on standard audiometry and as no significant difference between the ears to the patient.\n* Unilateral vestibular weakness. Unilateral vestibular weakness will be defined by caloric testing of a greater than 22% difference between ears using bithermal water irrigation.\n* Candidates for cochlear implantation by meeting traditional cochlear implant audiometric criteria.\n* Willingness and ability to comply with scheduled visits and study procedures.\n\nExclusion Criteria:\n\n* Patients with prior unilateral cochlear implantation\n* Asymmetric SNHL\n* Absence of unilateral vestibular weakness\n* Contraindication for caloric testing (including epilepsy, dysconjugate eye movements, and history of ear or eye surgery less than 2 months prior)\n* Alternative reasons for selecting cochlear implant laterality, including external. middle, or inner ear disease, anatomical abnormalities, or retrocochlear pathology\n* Pregnant women\n* Fetuses, neonates, children\n* Prisoners\n* Cognitively impaired adults","50 Years","99 Years",{"count":115,"type":21},10,[24],"In patients with symmetric hearing loss who meet traditional cochlear implant candidacy criteria yet demonstrate pre-operative unilateral vestibular weakness, the choice of which ear to implant may impact their post-operative vestibular course. The investigators aim to implement both objective videonystagmography metrics as well as subjective patient-reported outcome measures to assess whether selecting laterality for cochlear implantation as it relates to unilateral vestibular loss has a measurable impact on patients' post-operative vestibular function. In pursuing cochlear implantation on the ear that demonstrates worse vestibular function, the investigators hypothesize improved vestibular function in comparison to operating on the unaffected side. The randomized control pilot study plans to allocate 10 subjects to a treatment group that involves cochlear implantation on the ipsilateral side of vestibular hypofunction and a control group that will undergo implantation on the contralateral side. The investigators plan to compare scores derived from the Dizziness Handicap Inventory completed at pre-operative evaluation and at two subsequent post-operative visits between control and treatment groups as primary outcome. The investigators also plan to determine if there is a significant difference in measures derived from caloric vestibular testing pre- and post-operatively as well as between control and treatment groups.",[119,27],"Sensorineural Hearing Loss",[121,122,123,124],"cochlear implantation","sensorineural hearing loss","vestibular hypofunction","vestibular weakness","NOT_YET_RECRUITING","2026-03-06",{"date":128,"type":43},"2026-03-10",{"date":130,"type":21},"2026-04",{"date":132,"type":21},"2027-12",{"name":134,"class":50},"University of Virginia",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":144,"briefSummary":145,"conditions":146,"keywords":147,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":105},"100555850","optokinetic-virtual-reality-stimulation-in-unilateral-vestibular-hypofunction-100555850","NCT06517446","Optokinetic Virtual Reality Stimulation in Unilateral Vestibular Hypofunction","Effect of Optokinetic Virtual Reality Stimulation in Unilateral Vestibular Hypofunction Patients","Inclusion Criteria:\n\n* Diagnosed with unilateral vestibular hypofunction with VNG test,\n* Being between the ages of 18-65,\n* Being in the A+ class on the System Usability Scale (SCS) and having a value between 96-100 percentile\n\nExclusion Criteria:\n\n* Having bilateral vestibular hypofunction\n* Having a visual impairment,\n* Having a neurological disorder\n* Inability to communicate","65 Years",{"count":87,"type":21},[24],"The study will be conducted on patients diagnosed with UVH who apply to Prof. Dr. Mete İşeri Ear, Nose and Throat Diseases Polyclinic and Güneşli Erdem Hospital Ear, Nose and Throat and Vestibular Rehabilitation Unit. Participants will be divided into 3 groups by simple randomization (closed envelope) method. To the vestibular rehabilitation group; A conventional rehabilitation program based on structured Cawthorne Cooksey exercises will be applied for 45 minutes once a week with the support of a physiotherapist for 8 weeks. To the optokinetic stimulation group; optokinetic stimulation will be given with virtual reality glasses, and to the combined group; Participants in the vestibular exercise group will receive additional optokinetic stimulation. The application will be done once a week for 8 weeks. Inclusion criteria for the study are; diagnosed with unilateral vestibular hypofunction with VNG test, between the ages of 18-65, class A+ in the System Usability Scale (SUS) and the percentage range being between 96-100%; Exclusion criteria for the study are; Bilateral vestibular hypofunction, visual impairment, neurological disorder and inability to communicate.",[27],[148,149,150,151],"Unilateral Vestibular Hypofunction","Virtual Reality","Optokinetic stimulation","Motion Sickness","2026-03-02",{"date":154,"type":43},"2026-03-04",{"date":156,"type":43},"2025-09-07",{"date":158,"type":21},"2026-05-07",{"name":160,"class":50},"Istanbul Medipol University Hospital",{"id":162,"slug":163,"hasResults":11,"nctId":164,"briefTitle":165,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":16,"minAge":168,"maxAge":169,"enrollmentInfo":170,"targetDuration":4,"studyType":22,"phases":172,"briefSummary":173,"conditions":174,"keywords":175,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":51},"100597869","effects-of-mental-imagery-along-with-vestibular-rehabilitation-on-young-adults-with-vestibular-hypofunction-100597869","NCT07064096","Effects Of Mental Imagery Along With Vestibular Rehabilitation On Young Adults With Vestibular Hypofunction","EMI","Inclusion Criteria:\n\n* Patients with unilateral vestibular hypofunction\n* Head thrust test positive\n* Age group 20-40\n* DHI score 16 above\n* VSS score 11-30\n\nExclusion Criteria:\n\n* With any other associated neurological disorder that effect vestibular rehabilitation\n* Having bilateral vestibular hypofunction\n* Patients having any other associated disease that affects balance or cause vertigo other that vestibular","20 Years","40 Years",{"count":171,"type":21},44,[24],"The objective of the study is to determine the effects of cawthorne cooksey exercises with addition of mental imagery on vertigo,dizziness and balance in young adults with vestibular hypofunctionThe study will be randomized control trial including 2 experimental groups with estimated 22 participants in each group.",[27],[176,177,178],"VESTIBULAR REHAB WITH MENTAL IMAGERY","BALANCE","VERTIGO AND DIZZINESS","2025-07-03",{"date":181,"type":43},"2025-07-14",{"date":183,"type":43},"2025-07-01",{"date":185,"type":21},"2025-12-30",{"name":187,"class":50},"Riphah International University",{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":192,"acronym":193,"eligibilityCriteria":194,"healthyVolunteers":11,"sex":16,"minAge":195,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":198,"briefSummary":199,"conditions":200,"keywords":202,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":105},"100597640","effect-of-cawthorne-cooksey-exercises-on-balance-in-autistic-children-with-vestibular-hypofunction-100597640","NCT07061119","Effect of Cawthorne Cooksey Exercises on Balance in Autistic Children With Vestibular Hypofunction.","ASD","Inclusion Criteria:\n\n* Both genders\n* Peripheral Vestibular hypofunction.\n* Age:7-15years\n* Children with mild to moderate autism.\n* Children who understand and communicate\n\nExclusion Criteria:\n\n* Central Vestibular.\n* Acute Infection of inner ear\n* Auditory issues.\n* Patients unable to follow exercise plan","7 Years","15 Years",{"count":171,"type":21},[24],"The objective of the study is to determine the effects of cawthorne cooksey exercises on balance in autistic children with vestibular hypofunction. The study will be randomized control trial including 2 experimental groups with estimated 22 participants in each group.",[201,27],"Autism Spectrum Disorder",[203],"Autism, vestibular rehab in children, Autism and balance","2025-07-02",{"date":206,"type":43},"2025-07-11",{"date":208,"type":43},"2025-01-31",{"date":210,"type":21},"2025-07-31",{"name":187,"class":50},{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":218,"eligibilityCriteria":219,"healthyVolunteers":60,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":220,"targetDuration":4,"studyType":22,"phases":222,"briefSummary":223,"conditions":224,"keywords":225,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":240,"locationsCount":51},"100515036","improving-psychological-and-vestibular-health-mindgaps-100515036","NCT05986279","Improving Psychological and Vestibular Health: MINDGAPS","Improving Psychological and Vestibular Health Using a Novel Intervention: The Making Informed Decisions in Gaze and Postural Stability (MINDGAPS) System","MINDGAPS","Inclusion Criteria:\n\n* Veteran or Active Duty Military Service Member\n* Ability to stand independently\n* Legally autonomous and able to self-consent\n\nExclusion Criteria:\n\n* Acute head injury (within the previous 2 months)\n* History of moderate or severe head injury (i.e., loss of consciousness greater than 30 minutes or post-traumatic amnesia greater than 1 day)\n* Current diagnosis of spine disorders in the neck\n* Diagnosis of problems with the arteries in your neck\n* Blindness\n* If you have been diagnosed with abnormal eye movements (also called \"ocular motor palsy\")\n* If you have previously had a stroke or been diagnosed with a neurodegenerative disorder ( e.g., Parkinson's Disease, Multiple Sclerosis)\n* If you have been previously diagnosed primary vestibular dysfunction ( e.g., congenital peripheral vestibular syndrome)\n* If you have previously been diagnosed with a brain tumor\n* If you are currently receiving physical therapy care for balance or dizziness problems",{"count":221,"type":21},500,[24],"The purpose of this study is twofold: 1) Develop norms for measures of inner ear function and psychological health, and 2) Examine the feasibility of using the MINDGAPS system (a remote monitoring system) to track progress during physical therapy or rehabilitation for inner ear problems following a concussion or mild Traumatic Brain Injury.",[27],[226,227,228,229,230,231,232],"Rehabilitation","mild traumatic brain injury","dynamic visual acuity","gaze stability","postural stability","dizziness","psychological health","2024-12-03",{"date":235,"type":43},"2024-12-06",{"date":237,"type":43},"2023-08-30",{"date":239,"type":21},"2027-09-29",{"name":241,"class":50},"University of Montana"]