[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vibration\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vibration":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,48,73,98,127,159],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100053218","effect-of-dry-needling-plus-vibration-on-myofascial-trigger-points-in-individuals-with-nonspecific-low-back-pain-100053218",false,"NCT06527339","Effect of Dry Needling Plus Vibration on Myofascial Trigger Points in Individuals With Nonspecific Low Back Pain","Acceptability and Effectiveness of Adding a Percutaneous Vibratory Stimulus to Dry Needling for the Treatment of Myofascial Trigger Points in Nonspecific Low Back Pain: A Randomized Controlled Trial.","Inclusion Criteria:\n\n1. Individuals with NSLBP: pain persisting for more than six weeks, located between the twelfth rib and the buttocks, and scoring at least 3 points on the Numeric Pain Rating Scale;\n2. Presence of MTrPs in any of the following muscles that are associated with low back pain (erector spinae muscles, longissimus, iliocostalis, multifidus, gluteus maximus, gluteus medius, and quadratus lumborum);\n3. Aged between 35-65 years: this population exhibits the highest prevalence of low back pain and consequently represents the greatest socio-economic impact on society;\n4. Having signed the informed consent form.\n\nExclusion Criteria:\n\n1. Diagnosis of specific pathologies associated with low back pain (e.g., herniated discs, neurological disorders);\n2. Any form of infiltration within the past 3 months;\n3. Having received any physiotherapy interventions in the lumbopelvic region within the past 4 weeks;\n4. History of surgical intervention in the lumbopelvic region;\n5. Use of anticoagulant or antiplatelet medications within the last week;\n6. Presence of systemic or local lumbar infections;\n7. Pregnancy;\n8. Fear of needles (belonephobia).","ALL","35 Years","65 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","Low back pain is one of the most common health issues worldwide, and in most cases, this pain is nonspecific low back pain (NSLBP). NSLBP is characterized by the inability to determine the real source of the pain and commonly presents with myofascial trigger points (MTrPs) in the muscles related to the lumbar region.\n\nOne of the most widely used techniques for treating NSLBP by targeting MTrPs is dry needling (DN), a technique that involves inserting a needle to produce a mechanical effect capable of \"deactivating\" the MTrP and thereby alleviating its symptoms. However, some studies have concluded that other techniques are more effective than DN, such as percutaneous electrolysis (PE).\n\nWhen using the PE technique, it appears that adding a galvanic current enhances the effects of DN. Nonetheless, this poses a greater risk to the patient, as the galvanic current could damage nervous tissue if it comes into contact. For this reason, it is proposed to investigate whether other physical agents that are not electrical could enhance the effect of DN without increasing its risk. This is the case for vibration, a stimulus that has already been used successfully for the treatment of MTrPs, allowing us to investigate whether adding vibration to DN introduces therapeutic capabilities that:\n\n* Maintain or increase the effectiveness of DN in terms of pain and functional capacity.\n* Do not add risks for the patient, unlike PE.\n* Are less painful than DN and cause less post-needling pain than that generated after successive needle insertions with DN. Emphasizing these adverse effects is necessary since most clinical trials do not report these variables, which is fundamental for describing the safety of invasive techniques.\n\nFollowing this idea, the present project will analyze a new invasive therapy for the treatment of MTrPs: dry needling with vibratory stimulus (DN+V), for which the following hypotheses are proposed:\n\n* DN+V, instead of using an electrical stimulus like PE that could cause damage to some tissues, will apply vibration to the DN needles to increase the mechanical stimulus exerted on the MTrP, expecting greater benefits in terms of pain, functional capacity, muscle strength, and other variables of interest in individuals with NSLBP, and possibly requiring less treatment time than DN.\n* In DN, the repeated insertions and withdrawals of the needle in the MTrP provoke a hemorrhagic and inflammatory reaction that translates into hypersensitivity and microscopic tissue injury in the muscle, causing pain during treatment and post-needling pain for the following 24-32 hours. Another study showed that PE caused less post-needling pain than DN, which may be due to the fact that, unlike DN, it is common in PE to only perform a single puncture with each needle and not mobilize them.\n* The methodology for DN+V will be the same as for PE, with a single puncture and no needle manipulation, so it is expected that DN+V, being less invasive than DN, will reduce pain during treatment and post-needling pain compared to that generated by DN. There are studies that support this hypothesis, concluding that needle manipulation in DN produces greater post-needling pain than DN without needle manipulation.",[27,28,29,30],"Low Back Pain","Dry Needling","Trigger Points","Vibration",[32,33,34],"Non-specific low back pain","vibration dry needling","miofascial trigger points","NOT_YET_RECRUITING","2026-07-08",{"date":38,"type":39},"2026-07-13","ACTUAL",{"date":41,"type":21},"2026-09",{"date":43,"type":21},"2027-07",{"name":45,"class":46},"Universidad de Zaragoza","OTHER",2,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100632731","the-course-of-acute-respiratory-failure-in-geriatric-patients-with-hip-fracture-using-different-modes-of-a-vibroacoustic-device-for-the-lungs-100632731","NCT07517497","The Course of Acute Respiratory Failure in Geriatric Patients With Hip Fracture Using Different Modes of a Vibroacoustic Device for the Lungs","* respiratory failure;\n* hip fracture;\n* Injury Severity Score no higher than 8 points.\n\nExclusion Criteria:\n\n* All contraindications for use of the device:\n* terminal condition of the patient;\n* shock;\n* paradoxical pathological breathing;\n* hypertensive crisis;\n* severe hypocoagulation with a risk of hematoma formation or bleeding in the projection of exposure;\n* severe hypercoagulation, risk of thrombus\u002Fembolus migration along the main vessels in the area of exposure;\n* acute cerebrovascular accident in the first 1-3 days;\n* brain edema;\n* presence of multiple purulent or burn wound surfaces in the area of exposure;\n* presence of unstable rib fractures;\n* pneumomediastinum and\u002For subcutaneous emphysema of the chest;\n* osteomyelitis of the ribs and\u002For thoracic spine;\n* spinal fracture without orthopedic fixation;\n* chest or abdominal trauma with bleeding;\n* Injury Severity Score greater than 8 points;\n* concomitant diseases in the stage of decompensation.","60 Years","85 Years",{"count":57,"type":21},60,[24],"A medical professional trained in the procedure and use of the device will conduct the vibroacoustic therapy session. He will also take blood samples.\n\nIn the control group, patients will undergo vibroacoustic pulmonary therapy in the \"Pneumonia\" mode, and in the control group, in the \"Prevention\" mode. Vibroacoustic pulmonary therapy will be conducted over a period of 5 days. A similar algorithm of actions is planned for both groups. VALT sessions will be conducted 4-6 times a day for 5 minutes in combination with treatment according to the protocol for the use of \"Vibroacoustic Therapy\" of the lungs of the Ministry of Health of the Republic of Kazakhstan. The device's emitters will be applied to the affected areas of the lungs. Since the device has long cords for the emitters and is portable, it is not difficult to change the patient's position and does not require their active participation, which is important for patients on ventilators and with limited mobility.",[30,61],"Respiratory Complications","RECRUITING","2026-04-02",{"date":65,"type":39},"2026-04-08",{"date":67,"type":39},"2025-03-01",{"date":69,"type":21},"2027-12-01",{"name":71,"class":46},"Astana Medical University",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":16,"minAge":81,"maxAge":54,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":72},"100615520","iastm-and-vibration-effects-on-pain-functionality-and-kinesiophobia-in-lumbar-disc-herniation-100615520","NCT07293676","IASTM and Vibration Effects on Pain, Functionality, and Kinesiophobia in Lumbar Disc Herniation","The Effects of Instrument-Assisted Soft Tissue Mobilization and Vibration Therapy on Pain, Functionality, and Kinesiophobia in Individuals With Lumbar Disc Herniation","Inclusion Criteria:\n\n* Individuals between 30 and 60 years of age\n* Individuals diagnosed with lumbar disc herniation at the protrusion level\n* Individuals with no cognitive, intellectual, or mental impairments and who are able to express themselves\n* Individuals with a VAS score greater than 5\n* Individuals experiencing pain for at least 3 months\n\nExclusion Criteria:\n\n* Individuals with a history of lumbar surgery\n* Individuals who are pregnant\n* Individuals who have had a spinal tumor or any other malignancy within the past six months\n* Individuals who have received physiotherapy for low back pain within the last six months\n* Individuals with orthopedic conditions such as fractures\n* Individuals diagnosed with neurological, rheumatological, or psychological disorders\n* Individuals with diagnoses such as infection, spondylosis, spondylolysis, osteoporosis, or ankylosing spondylitis will be excluded from the study.",true,"30 Years",{"count":83,"type":21},45,[24],"The aim of this study is to investigate the effects of Instrument-Assisted Soft Tissue Mobilization and vibration massage therapy on pain, functionality, and kinesiophobia in individuals with lumbar disc herniation.",[30,87,88],"Lumbar Disc Herniation","Soft Tissue Mobilization","2026-03-24",{"date":91,"type":39},"2026-03-27",{"date":93,"type":39},"2026-01-05",{"date":95,"type":21},"2026-05-15",{"name":97,"class":46},"Istanbul Medipol University Hospital",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":80,"sex":16,"minAge":106,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":22,"phases":109,"briefSummary":110,"conditions":111,"keywords":112,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":72},"100625548","non-invasive-vibratory-stimulation-of-the-knee-muscles-for-the-improvement-of-the-somatosensory-input-and-motor-performance-100625548","NCT07424066","Non-invasive Vibratory Stimulation of the Knee Muscles for the Improvement of the Somatosensory Input and Motor Performance","Stimolazione Vibratoria Non-invasiva Per il Miglioramento Del Ritorno Sensoriale e Della Performance Motoria in Atleti Con Lesione al Legamento Crociato Anteriore","VIBMOT","Inclusion Criteria:\n\n* Age equal to or greater than 18 years.\n\nExclusion Criteria:\n\n* Neurological disorders.\n* Musculoskeletal injuries, including previous ones, that may compromise the execution of required movements.\n* Cardiorespiratory disorders.","18 Years",{"count":108,"type":21},35,[24],"The goal of this interventional cross-sectional study is to evaluate motor responses to non-invasive vibratory stimulation applied to the hamstring muscle tendons in healthy individuals. Knee flexion and extension efforts, in both isometric and concentric contractions, will be tested.\n\nThe investigators hypothesize that vibratory stimulation causes an increase in activity in the flexor muscles (hamstrings) and a decrease in the extensor muscles (quadriceps) of the knee in all motor tasks. It follows that during knee flexion (both concentric and isometric), vibratory stimulation should cause an increase in the distance between the angular trajectories of the knee obtained with and without vibratory stimulation (with a positive sign). The increased activity of the hamstring muscles would, in fact, contribute to increasing the velocity of the flexor movement. Conversely, during extensor movements (both concentric and isometric), vibratory stimulation should reduce the instantaneous velocity of the movement, therefore causing an increase in distance (with a negative sign) between the trajectories obtained with and without stimulation.\n\nParticipants will be tested using an isokinetic dynamometer and they will be asked to perform the following motor tasks in a random order: concentric knee flexion, concentric knee extension, isometric knee flexion, and isometric knee extension. The dominant limb will be tested, only. The assessment will be performed one time.",[30],[113,114,115,116,117],"vibratory stimulation","muscle spindle","muscle contraction","spinal reflex","somatosensory system","2026-02-13",{"date":120,"type":39},"2026-02-20",{"date":122,"type":39},"2025-05-20",{"date":124,"type":21},"2026-12-31",{"name":126,"class":46},"University of Milano Bicocca",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":80,"sex":16,"minAge":106,"maxAge":55,"enrollmentInfo":134,"targetDuration":4,"studyType":22,"phases":136,"briefSummary":137,"conditions":138,"keywords":143,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":72},"100619139","sensory-mechanisms-of-manual-dexterity-recovery-after-stroke-a-prospective-cohort-study-of-prediction-and-cerebral-correlates-100619139","NCT07340736","Sensory Mechanisms of Manual Dexterity Recovery After Stroke: a Prospective Cohort Study of Prediction and Cerebral Correlates","HapticS 2","Inclusion Criteria:\n\n* First symptomatic stroke, ischaemic or haemorrhagic in the early subacute phase (up to 3 weeks post-stroke)\n* Upper limb paresis (≤4\u002F5 MRC Scale)\n* Ability to grasp, lift and put down 1 block (from the BBT test)\n* Be affiliated to a social security\n\nExclusion Criteria:\n\n* Presence of another neurological or musculoskeletal condition affecting upper limb movement\n* Severe cognitive impairment and\u002For aphasia with inability to understand and carry out instructions\n* Contraindications to MRI (claustrophobia, presence of cochlear implants and\u002For pacemakers)\n* Persons subject to legal protection measures\n* Persons subject to judicial protection measures\n* Pregnancy\n* Life-threatening conditions or conditions requiring follow-up at 6 months\n* Epilepsy\n* Known hypersensitivity or allergy to silicone",{"count":135,"type":21},90,[24],"In the proposed research, we will assess motor and sensory functions of the hand using clinical tests and a tool designed to measure manual dexterity combined with vibrotactile stimulation. We will also evaluate the integrity of brain structure and function using MRI.",[139,140,141,142,30],"Stroke","Upper Extremity Paresis","Manual Dexterity","Sensory Integration Dysfunction",[144,145,146,147,148,149,150],"stroke","haptic","vibration","sensorimotor impairment","manual dexterity","prediction of recovery","MRI",{"date":152,"type":39},"2026-01-14",{"date":154,"type":21},"2026-03-01",{"date":156,"type":21},"2028-03-01",{"name":158,"class":46},"Centre Hospitalier St Anne",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":164,"acronym":4,"eligibilityCriteria":165,"healthyVolunteers":11,"sex":16,"minAge":106,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":22,"phases":168,"briefSummary":169,"conditions":170,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":72},"100613859","the-effect-of-home-based-walking-on-symptoms-and-health-profile-of-hemodialysis-patients-100613859","NCT07272070","The Effect of Home-Based Walking on Symptoms and Health Profile of Hemodialysis Patients","The Effect of Home-Based Walking on Symptoms and Health Profile of Hemodialysis Patients:Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients who agreed to participate in the research during the data collection process,\n* Over 18 years of age,\n* Speak and understand Turkish,\n* Are at least literate,\n* Can perform daily living activities independently,\n* Own a smartphone.\n\nExclusion Criteria:\n\n* Do not have sufficient cognitive ability,\n* Have arthritic or orthopedic problems requiring assistance with walking,\n* Have significant visual or hearing impairments,\n* Walk regularly,\n* Have a hemoglobin level \\\u003C8 mg\u002Fdl,\n* Have Stage IV of New York heart failure.",{"count":167,"type":21},24,[24],"This study aims to evaluate the effect of 8 weeks of home-based moderate-speed walking on hemodialysis symptoms and health profile while patients are receiving hemodialysis treatment.\n\nDue to permanent deterioration in kidney function, patients need hemodialysis treatment, which is the most commonly used treatment method among renal replacement therapies. Hemodialysis treatment causes a series of physical and psychological problems. Problems such as hypotension, headache, nausea, muscle cramps, itching and pain are physical problems, while depression, anxiety, cognitive disorders and stress are psychological problems. In addition, it has been reported that long-term hemodialysis treatment and all the resulting problems increase the tendency to a sedentary lifestyle in this patient group, leading to a decrease in physical function and activity, and indirectly to a low quality of life and low survival rates. For this reason, hemodialysis patients have difficulty meeting their daily activities and needs, and their dependency and healthcare burden increase. Adopting a sedentary lifestyle by these patients prevents them from managing both the physical and psychological problems of hemodialysis and their conditions such as hypertension and diabetes mellitus, and causes the disease to progress. Physical exercises, which are considered among the useful therapeutic suggestions in addition to pharmacological treatments in the management of the negative situations that arise, are considered as an easy, useful and effective intervention method. Kidney Disease: Improving Global Outcomes (KDIGO) recommends 30 minutes of moderate-intensity physical exercise at least 5 days a week. Additionally, it should not be overlooked that whether patients have places to do physical activity and what their facilities are are a detail that should be questioned by health professionals. Patients without suitable accommodations should be encouraged to engage in physical activity, especially in indoor spaces like home. Home-based walking exercise is known to be easy, inexpensive, and safe, and is also advantageous when the weather is not favorable. When we examined the studies in which home-based walking exercise was performed, it was determined that its effect on functional capacity was generally investigated, but its effect on the health outcomes and symptoms of patients receiving hemodialysis treatment was not evaluated. There was no evidence that home-based walking exercise had any effect on symptoms in patients receiving HD treatment. Therefore, it was planned to conduct a study to evaluate whether home-based walking exercise has an effect on patient health outcomes.",[171,172,30,173],"Muscle Cramp","Hemodialysis","Stretching","2025-11-26",{"date":176,"type":39},"2025-12-09",{"date":178,"type":21},"2025-12-15",{"date":180,"type":21},"2026-06-30",{"name":182,"class":46},"Figen Akay"]