[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"video-assisted-thoracic-surgery-vats\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:video-assisted-thoracic-surgery-vats":212},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,50,79,104,136,161,186],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100635477","comparison-of-serratus-posterior-superior-intercostal-plane-block-and-deep-serratus-anterior-plane-block-after-video-assisted-thoracoscopic-surgery-100635477",false,"NCT07553195","Comparison of Serratus Posterior Superior Intercostal Plane Block and Deep Serratus Anterior Plane Block After Video-Assisted Thoracoscopic Surgery","Comparison of Serratus Posterior Superior Intercostal Plane Block and Deep Serratus Anterior Plane Block After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective video-assisted thoracoscopic surgery\n* Body mass index (BMI) between 18 and 35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\\u003C18 or \\>35 kg\u002Fm²","ALL","18 Years","65 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Deep Serratus Anterior Plane Block in patients undergoing Video-Assisted Thoracoscopic Surgery. The primary outcome is Visual Analog Scale (VAS) during the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block performance time, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection), Patient satisfaction assessed using a Likert scale, Quality of recovery assessed using the QoR-15 questionnaire.",[27,28,29,30],"Postoperative Pain","Video Assisted Thoracic Surgery (VATS)","Serratus Posterior Superior Intercostal Plane Block","Deep Serratus Anterior Plane Block",[32,33,34,35,36],"spsıp","vats","sap","Serratus posterior superior intercostal block","deep serratus anterior plane block","NOT_YET_RECRUITING","2026-05-07",{"date":40,"type":41},"2026-05-11","ACTUAL",{"date":43,"type":21},"2026-11-30",{"date":45,"type":21},"2028-04-30",{"name":47,"class":48},"Antalya City Hospital","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":49},"100634470","serratus-posterior-superior-intercostal-plane-block-versus-intrathecal-morphine-in-vats-100634470","NCT07540104","Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATs","Comparison of the Effects of Serratus Posterior Superior Intercostal Plane Block and Intrathecal Morphine on Postoperative Acute Pain in Patients Undergoing Video-assisted Thoracoscopic Surgery","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* American Society of Anesthesiologists physical status I to III\n* Scheduled for elective video-assisted thoracoscopic surgery including wedge resection, segmentectomy, or lobectomy\n\nExclusion Criteria:\n\n* Refusal to participate\n* Pregnancy\n* Morbid obesity (body mass index greater than 40 kg per square meter)\n* Allergy to opioids, local anesthetics, or nonsteroidal anti-inflammatory drugs\n* Neuropsychiatric disorders, cognitive impairment, or inability to communicate\n* History of substance abuse\n* Use of anticoagulant therapy or presence of bleeding disorders\n* Active systemic infection\n* Severe cardiovascular, hepatic, renal, or endocrine disease\n* Chronic pain syndrome or ongoing chronic pain treatment\n* Emergency surgery or prior ipsilateral thoracic surgery\n* Preoperative opioid use\n* Significant intraoperative or postoperative bleeding or hemodynamic instability\n* Requirement for prolonged postoperative mechanical ventilation longer than 18 hours","75 Years",{"count":20,"type":21},[24],"This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery.\n\nThis is a prospective, randomized, controlled, single-center clinical trial including adult patients undergoing elective thoracoscopic surgery. Participants will be randomly assigned to receive either a serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia.\n\nThe primary outcome is cumulative opioid consumption during the first 24 postoperative hours, expressed as intravenous morphine milligram equivalents. Secondary outcomes include pain scores, time to first analgesic request, quality of recovery, and postoperative complications.\n\nThe study aims to determine whether these two techniques differ in their effectiveness for postoperative pain management.",[62,27,28],"Thoracic Anesthesia",[64,65,66,67,68],"Thoracic Surgery, Video-Assisted","Analgesia, Postoperative","Morphine","Injections, Spinal","Nerve Block","RECRUITING","2026-04-28",{"date":72,"type":41},"2026-05-04",{"date":74,"type":21},"2026-04-15",{"date":76,"type":21},"2026-09-30",{"name":78,"class":48},"Ondokuz Mayıs University",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":49},"100633899","effect-of-early-versus-late-surgical-intercostal-block-on-postoperative-pain-relief-following-video-assisted-thoracic-surgery-vats-100633899","NCT07532681","Effect of Early Versus Late Surgical Intercostal Block on Postoperative Pain Relief Following Video-Assisted Thoracic Surgery (VATS)","Effect of Early Versus Late Surgical Intercostal Block on Postoperative Pain Relief Following Video-Assisted Thoracic Surgery (VATS): a Randomised, Double-blind Study","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for single-port or two-port video-assisted thoracoscopic surgery (VATS).\n* ASA classification 1 to 3\n* Able to understand the study, describe their pain and provide valid informed consent\n\nExclusion Criteria:\n\n* Neurological or psychiatric conditions that compromise the reliable assessment of pain(dementia, cognitive impairment, severe communication disorders)\n* Chronic opioid use or regular use (\\> 3 months) of strong analgesics for chronic pain\n* History of allergy or known hypersensitivity to local anaesthetics\n* Coagulopathy or anticoagulant therapy precluding the safe performance of an intercostal block\n* Local infection at the injection site or active systemic infection\n* Bilateral thoracic surgery or intraoperative conversion to thoracotomy\n* Second surgery at the same site.\n* Current pregnancy or breastfeeding\n* Inability to understand postoperative instructions or a language barrier preventing a validated assessment of pain\n* Simultaneous participation in another clinical trial involving analgesia or thoracic surgery\n* Refusal to participate or withdrawal of consent at any time",{"count":87,"type":21},140,[24],"Video-assisted thoracoscopic surgery (VATS) is associated with significant postoperative pain despite lower morbidity compared with thoracotomy. Adequate pain management is essential within Enhanced Recovery After Surgery (ERAS) pathways to preserve respiratory function and facilitate postoperative recovery. Surgical intercostal block performed under direct vision is a simple and effective regional analgesic technique commonly used following VATS. However, the optimal timing of intercostal block administration during surgery remains uncertain.\n\nThis prospective randomized double-blind study will compare surgical intercostal block performed at the beginning versus the end of the surgical procedure. The study aims to evaluate the effect of block timing on postoperative pain intensity and postoperative opioid consumption. The results may help optimize multimodal analgesic strategies in patients undergoing thoracic surgery.",[28,91],"Intercostal Nerve Block",[93,91,94],"VATS","Pain","2026-04-09",{"date":97,"type":41},"2026-04-16",{"date":99,"type":21},"2026-04-01",{"date":101,"type":21},"2027-09-30",{"name":103,"class":48},"Erasme University Hospital",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":117,"conditions":118,"keywords":122,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":49},"100609345","phase-2-high-dose-dexamethasone-to-reduce-postoperative-pain-after-video-assisted-thoracoscopic-surgery-lobectomy-segmentectomy-100609345","NCT07213375","High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy \u002FSegmentectomy","High Dose Dexamethasone In High-Pain Responders Undergoing Enhanced Recovery Video-Assisted Thoracoscopic Surgery Lobectomy and Segmentectomy - A Randomized Double-Blinded Controlled Trial","DEXTER","Inclusion Criteria:\n\n* Age ≥ 18 year\n* Able to understand written and spoken Danish language\n* PCS ≥20\n* Signed written informed consent form.\n* Patient planned to elective VATS lobectomy\u002Fsegmentectomy\n\nExclusion Criteria:\n\n* Patients undergoing systemic glucocorticoid or other immunosuppressive therapies, ex-cluding inhaled steroids.\n\n  * Individuals with diabetes requiring insulin treatment.\n  * Pregnant or breastfeeding patients.\n  * Patients with known allergies to the study drug.\n  * Individuals with mental disabilities that may impair their capacity to provide informed consent or compromise the validity of data collection.\n  * Patients with diagnosed schizophrenia, active psychosis, bipolar disorder, or a history of ongoing treatment with antipsychotic and\u002For antidepressant medications.\n  * Individuals with altered pain perception due to other conditions or injuries, such as spi-nal cord or brain injuries, severe polyneuropathies, or neurological disorders.\n  * Regular users of opioid medications.\n  * Patients requiring reoperation within the first two postoperative days.\n  * Individuals undergoing conversion to a surgical procedure other than VATS lobecto-my\u002Fsegmentectomy.",{"count":113,"type":21},80,[115,116],"PHASE2","PHASE3","The aim is to conduct a randomized controlled trial (RCT) with a high dose arm (1mg\u002Fkg) vs a low dose (8mg in total) of steroid (Dexamethasone) given intravenous (IV) after the induction of anesthesia to \"High-pain-responders\" in patients undergoing VATS lobectomy\u002Fsegmentectomy.\n\nThe hypothesis is that a high dose of Dexamethasone can lower pain when coughing in the morning after VATS lobectomy\u002Fsegmentectomy, in patients scoring as \"High-pain-responders\" on the Pain-Catastrophizing-Scale",[119,120,28,121],"Analgetic","Lung Cancer (NSCLC)","Glucocorticoid",[123,124,93,125,126],"Pain catastrophizing","ERAS","Lung cancer","Minimizing pain","2026-01-05",{"date":129,"type":41},"2026-01-07",{"date":131,"type":41},"2025-09-01",{"date":133,"type":21},"2026-11",{"name":135,"class":48},"Rigshospitalet, Denmark",{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":149,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":49},"100438548","qor40-between-intercostal-block-and-intercostal-block-and-serratus-plane-catheter-during-vats-100438548","NCT04990713","QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS","QORVATS Study. A Randomized Controlled, Triple Blinded to Compare the Quality of Recovery (QoR 40) Between Intercostal Block and a Combination of Intercostal Nerve Block With Serratus Plane Catheter for Patient's Undergoing VATS Procedures.","Inclusion Criteria:\n\n* Patients undergoing elective VATS lung resections including wedge resection, segmentectomy, bi-lobectomy, or lobectomy.\n* Age \\> 18 years.\n* ASA (American Society of Anesthesiology) Score - 1 to 4.\n* Gender - all genders\n* Patients able to consent to participate in the study\n\nExclusion Criteria:\n\n* Patient refusal to participate in the study.\n* Emergency surgery.\n* Allergies to local anesthetics\n* BMI\\>40\n* Presence of local (chest wall) or systemic infection.\n* Previous lung resection on the same hemithorax.\n* Patient suffering from chronic pain defined by persistent pain more than six month.\n* Conversion to thoracotomy",{"count":144,"type":21},200,[24],"Video assisted thoracic surgery (VATS) has emerged as standard of care for majority of thoracic surgeries. It is less invasive compared to thoracotomy and is associated with improved perioperative outcomes \\[1-3\\]. Good perioperative analgesia after thoracic surgery will enable pulmonary toilet, early chest physiotherapy and mobilisation, \\[4,5,6\\]. Thirty-day hospital visits and hospital readmissions at London Health Sciences Centre (LHSC) is around 21% and 9% respectively \\[7\\]. One of the top five determinant for hospital visit and readmission in 30 days, was persistent post operative pain \\[7\\].\n\nSeveral options to analgesia are available for patients undergoing VATS procedure. Systemic opioid based multimodal analgesia, central neuraxial blocks like thoracic epidural and peripheral nerve blocks are different available options, and their practise varies across institution \\[4,8,9\\]. Thoracic epidural or paravertebral blocks can be challenging to perform with high failure rates \\[10-12\\].\n\nFascial plane blocks (SAB; ESP) are in vogue in the present era \\[13-16\\]. They are easy to perform and do not require similar dexterity as needed to perform thoracic epidural or paravertebral blocks. They have minimal side effects and provide the options for continuous infusion for prolonged analgesia. They have become an effective part of multimodal analgesia and have established their roles in ERAS (enhanced recovery after surgery) protocol for VATS procedures.\n\nSAB has become a common practise at our institution with proved clinical efficacy.\n\nPerioperative Surgical Home is a patient centric team-based approach to improve patient's experiences in the perioperative period and thus improve healthcare \\[17\\]. Quality of Recovery (QoR) is a key determinant to perioperative surgical home and can be measured using the QoR 40 score \\[18\\]. This is a well validated score with a minimal important clinical difference (MICD) of 6.3 \\[19\\]. Quality of recovery combines five dimensions of health: patient support, comfort, emotions, physical independence and pain to achieve a single patient outcome - improved patient care \\[18\\].\n\nThe investigators hypothesize the that patients undergoing VATS lung resections using a combination of intercostal nerve block plus continuous SAB catheter infusion of local anesthetics will have a 20% increase in their QoR-40 score 24hour after the surgery compared to a single shot intercostal nerve block.",[28,148],"Pain Management",[150,151],"Intercostal Block","Fascial Plane Block","2025-08-27",{"date":154,"type":41},"2025-09-04",{"date":156,"type":41},"2022-06-30",{"date":158,"type":21},"2026-01-31",{"name":160,"class":48},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's",{"id":162,"slug":163,"hasResults":11,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":93,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":168,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":171,"briefSummary":172,"conditions":173,"keywords":174,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":49},"100592689","erector-spinae-plane-block-versus-serratus-anterior-plane-block-in-vats-100592689","NCT06996691","Erector Spinae Plane Block Versus Serratus Anterior Plane Block in VATS","A Comparative Study of Erector Spinae Plane Block Versus Serratus Anterior Plane Block for Postoperative Analgesia After Video-assisted Thoracoscopic Surgery","Inclusion Criteria:\n\n* body mass index (BMI)=18 to 40 kg\u002Fm2\n\nExclusion Criteria:\n\n* Contraindications to regional anesthesia as bleeding disorders , allergy to local anesthetic or infection at block site\n* pre-existing chronic pain\n* history of opiate abuse\n* sepsis","70 Years",{"count":170,"type":21},40,[24],"Pain control remains challenging in patients undergoing video-assisted thoracoscopic surgery (VATS). It is advised to use a regional block to lower postoperative opioid usage. This study evaluates efficacy of Erector spinae plane (ESP) block in comparison to Serratus anterior plane block (SAP) in pain management for patients undergoing video-assisted thoracoscopic surgery(VATS).",[28],[93,175,176],"Erector spinae plane block","Serratus anterior plane block","2025-05-21",{"date":179,"type":41},"2025-05-30",{"date":181,"type":41},"2025-05-01",{"date":183,"type":21},"2025-08-15",{"name":185,"class":48},"Ain Shams University",{"id":187,"slug":188,"hasResults":11,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":193,"targetDuration":4,"studyType":22,"phases":195,"briefSummary":196,"conditions":197,"keywords":200,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":49},"100578580","effectiveness-of-respiratory-muscle-training-with-a-mobile-application-after-lobectomy-100578580","NCT06813144","Effectiveness of Respiratory Muscle Training with a Mobile Application After Lobectomy","Evaluation of the Effectiveness of Respiratory Muscle Training with a Mobile Application in the Early Postoperative Period After Lobectomy","Inclusion Criteria:\n\n* Volunteering to participate in the study,\n* Being clinically stable,\n* Being a lung cancer patient with a planned lobectomy with VATS,\n* Being between the ages of 18-65,\n* Being able to cooperate with the tests to be performed.\n\nExclusion criteria:\n\n* Having any orthopedic or neurological problem that prevents walking,\n* Having undergone any surgery related to the thoracic wall,\n* Having diseases that will affect respiratory parameters such as severe heart failure, severe chronic obstructive pulmonary disease (COPD).",{"count":194,"type":21},45,[24],"It has been observed that there are negative effects on respiratory muscle strength following lobectomy. This has led to the necessity of respiratory muscle training to mitigate these adverse effects. Most studies conducted so far focus on the late postoperative period, and there are only a few studies evaluating the effectiveness of early postoperative inspiratory muscle training (IMT). It is believed that this method could be useful for facilitating patient follow-up and increasing patient motivation through visual feedback.",[28,198,199,120],"Thoracic Surgery","Respiratory Muscle",[201,33,202],"lung cancer","inspiratory muscle training","2025-02-03",{"date":205,"type":41},"2025-02-06",{"date":207,"type":21},"2025-03-01",{"date":209,"type":21},"2026-02-01",{"name":211,"class":48},"Hacettepe University","Video-assisted Thoracic Surgery (VATS)"]