[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"virtual-reality-cognitive-training\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:virtual-reality-cognitive-training":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100631098","virtual-reality-cognitive-intervention-for-critically-ill-delirium-survivors-vr-cog-100631098",false,"NCT07496255","Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)","Inclusion Criteria:\n\n* Adults aged 50 years or older\n* English speaking\n* Admitted to the intensive care unit (ICU) with acute respiratory failure\u002Finvasive mechanical ventilation\n* Screening positive for delirium (using Richmond Agitation Sedation Scale and Confusion Assessment Method for the ICU)\n\nExclusion Criteria:\n\n* Acute neurologic injury such as stroke, traumatic brain injury, brain mass, intracranial hemorrhage, seizures, or central nervous system infection\n* Chronic cognitive or physical function deficit preventing participation in study interventions or assessments (determined by chart diagnoses and direct participant interview)\n* Chronic cognitive impairment (including mild cognitive impairment or dementia) identified by chart diagnosis, prescription of anti-dementia medications, or Informant Questionnaire on Cognitive Decline in the Elderly Score (IQCODE) \\>3.3 obtained from family caregiver\n* Severe, uncorrected vision or hearing impairment preventing participation in intervention or outcomes assessments\n* Admitted with acute alcohol or drug intoxication or withdrawal\n* Severe, uncontrolled psychiatric disorder (bipolar disorder or schizophrenia)\n* History of severe vertigo, motion-induced sickness, headaches, light sensitivity, seizures, or prior intolerance of virtual reality (VR)\n* Receiving comfort care measures or not expected to survive the hospitalization\n* Prisoners or patients unable to provide consent\n* Not expected to be discharged home from the hospital, or living more than 50 miles from the nearest recruitment site, or homeless","ALL","50 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this study is to measure the feasibility, acceptability of virtual reality (VR) brain games and estimate their effect on memory, attention, and mood for ICU survivors. The VR program will be used at home through a headset and hand controls.",[25,26,27,28],"Intensive Care Unit Delirium","Intensive Care Acquired Cognitive Impairment","Post Intensive Care Unit Syndrome","Virtual Reality Cognitive Training","RECRUITING","2026-04-15",{"date":32,"type":33},"2026-04-17","ACTUAL",{"date":35,"type":33},"2026-03-19",{"date":37,"type":19},"2027-07-15",{"name":39,"class":40},"Indiana University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":20,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":41},"100611788","virtual-reality-exposure-therapy-for-obsessive-compulsive-disorder-a-randomized-controlled-trial-in-inpatients-100611788","NCT07245134","Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients","Virtual Reality Exposure Therapy in Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients","OCD-VRET1","Inclusion Criteria:\n\n* Diagnosis of OCD (F42) using currently valid DSM-V and ICD-11\n* Fluent in Czech\n\nExclusion Criteria:\n\n* Any other psychiatric, neurological and serious somatic illness\n* Substance abuse\n* Psychotropic medication (e.g. benzodiazepines) except antidepressants, antipsychotic medication and hypnotics.\n* Contradictions to using a virtual reality (e.g., epilepsy, balance problems)\n* Pregnancy\n* Cardiostimulator and mental implants","17 Years","55 Years",{"count":53,"type":19},62,[22],"The aim of this study is to evaluate the efficacy of virtual reality exposure therapy (VRET) as a treatment for obsessive-compulsive disorder (OCD). Participants are randomly assigned to one of the following interventions: a) exposure condition - the group with a standard CBT program enriched with exposure therapy in VR (VRET), b) control condition 1 - the group with a standard CBT program enriched with VR cognitive training aimed at cognitive flexibility or c) control condition 2 - standard CBT program without any additional VR intervention. The treatment effect will be evaluated using pre\u002Fpost assessments, as well as monitoring adherence to exposure and response prevention assignments.",[57,58,28,59],"Obsessive-Compulsive Disorder","Virtual Reality Exposure Therapy","Cognitive Behavior Therapy",[61,62,63,64],"obsessive-compulsive disorder","VR exposure therapy","cognitive flexibility","Inpatient clinic","2025-11-20",{"date":67,"type":33},"2025-11-24",{"date":69,"type":33},"2022-11-15",{"date":71,"type":19},"2026-12-30",{"name":73,"class":40},"National Institute of Mental Health, Czech Republic",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":15,"minAge":81,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":20,"phases":84,"briefSummary":85,"conditions":86,"keywords":92,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":41},"100602565","immersive-virtual-reality-in-cognitive-rehabilitation-of-patients-with-post-stroke-cognitive-impairment-100602565","NCT07125170","Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment","Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment: A Pilot Study at the Department of Physical Medicine and Rehabilitation, Clinical Hospital of the University of Chile","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients with a cerebrovascular accident of any etiology with less than 3 months of progression\n* Patients with mild to moderate cognitive impairment post-stroke (impairment in at least one cognitive domain)\n* MoCA score of less than 24 points\n* Referred for cognitive rehabilitation at the Occupational Therapy Unit of HCUCH\n\nExclusion Criteria:\n\n* Patients with refractive errors that prevent the use of the headset\n* Patients with any type of aphasia that prevents the administration of the MoCA test\n* Patients with severe psychiatric disorders (presence of psychotic symptoms or derealization)\n* Patients with severe motor impairments (lack of trunk control or global strength of both upper limbs \\\u003C M3)","18 Years",{"count":83,"type":19},20,[22],"This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy. Participants will use a head-mounted display and interactive software to engage in gamified cognitive exercises that simulate memory, attention, and executive function tasks. The intervention consists of 10 sessions, delivered two to three times per week over a period of approximately four weeks. The study will assess multiple feasibility indicators, including the recruitment rate based on eligibility criteria, the safety and tolerability of VR sessions for participants, and the usability and satisfaction reported by occupational therapists administering the intervention. Additionally, exploratory outcomes include changes in global cognition and specific cognitive domains, as well as self-reported quality of life. Adverse effects related to VR use will be tracked. This pilot study will help inform the design and implementation of future, larger-scale clinical trials.",[87,88,89,90,28,91],"Stroke","Post-Stroke Cognitive Impairment (PSCI)","Cognitive Dysfunction","Virtual Reality Therapy","Cognitive Rehabilitation",[93,94,95,96,97,98,99,100],"virtual reality","Cognitive rehabilitation","Immersive Therapy","Meta Quest 3","Kinesix XR","Occupational Therapy","Montreal Cognitive Assessment (MoCA)","Simulator Sickness Questionnaire (SSQ)","2025-08-08",{"date":103,"type":33},"2025-08-15",{"date":105,"type":33},"2025-08-06",{"date":107,"type":19},"2026-05-01",{"name":109,"class":40},"University of Chile"]