[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"visual-perception\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:visual-perception":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100608958","early-phase-1-restructuring-the-alpha-gamma-code-in-aging-vision-100608958",false,"NCT07208318","Restructuring the Alpha-Gamma Code in Aging Vision","Rescuing Visual Perception in Aging Adults by Restructuring the Alpha-Gamma Neural Code","Inclusion Criteria:\n\n* 18+ years of age or older\n* normal or corrected-to-normal visual acuity, color vision, and stereo vision\n\nExclusion Criteria:\n\n* not pregnant,\n* no metal implants in head,\n* no implanted electronic devices,\n* no history of neurological problems or head injury,\n* no skin sensitivity,\n* no claustrophobia,\n* no dementia (normal Mini Mental State Examination between 24-30; Montreal Cognitive Assessment \\> 25)\n* no depression (normal Beck Depression Inventory II \\\u003C13; Geriatric Depression Scale \\\u003C 10)\n* no ophthalmological diseases (e.g., strabismus, glaucoma, cataract, macular degeneration)\n* no history of psychosis\n* no cognitive deficits (MMSE score\\>24; MoCA\\>25)\n* cannot be taking any psychoactive medication.",true,"ALL","18 Years",{"count":20,"type":21},240,"ESTIMATED","INTERVENTIONAL",[24],"EARLY_PHASE1","Tests whether age-related visual deficits arise from disrupted alpha-gamma coupling in visual cortex (V1) and MT. Uses fMRI, source-resolved HD-EEG, and personalized complex-waveform HD-tACS to (1) quantify aging effects on phase-amplitude coupling, (2) drive PAC into a preferred \"gamma-at-alpha-troughs\" state, and (3) bidirectionally change perception by aligning gamma to alpha troughs vs peaks. Two five-day, double-blind, sham-controlled studies (n=120 each) target contrast sensitivity (V1) and 3D shape-from-motion (MT), aiming for mechanistic insight and remediation in older adults with implications for ADRD.",[27,28,29],"Aging","Visual Perception","Noninvasive Brain Stimulation","NOT_YET_RECRUITING","2025-09-27",{"date":33,"type":34},"2025-10-06","ACTUAL",{"date":36,"type":21},"2026-01-10",{"date":38,"type":21},"2030-08-31",{"name":40,"class":41},"Boston University Charles River Campus","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":65},"100514667","visual-perception-difficulties-after-stroke-100514667","NCT05981482","Visual Perception Difficulties After Stroke","Accuracy and Utility of the Oxford Visual Perception Screening (OxVPS), a Screening for Visual Perception Difficulties in Stroke Survivors","Inclusion Criteria:\n\n* Patients with a clinical diagnosis of stroke (ischemic stroke and\u002For intracerebral haemorrhage).\n* Within 6 weeks of confirmed stroke.\n\nExclusion Criteria:\n\n* Insufficient understanding of English\n* Clinical concerns that patient is unable follow simple instructions.\n* Clinical concerns that patient is unable to concentrate for 15 minutes.\n* No capacity to provide informed consent.",{"count":50,"type":21},200,"OBSERVATIONAL","The goal of this observational study is to learn how well the Oxford Visual Perception Screening (OxVPS) tool can identify stroke survivors with visual perception difficulties.\n\nThe main aim is to determine the accuracy and utility of the OxVPS compared to the current gold standard assessment in stroke survivors. In other words, how well can the Oxford Visual Perception Screening tool (OxVPS) identify stroke patients with visual perception problems?\n\nParticipants will completed the OxVPS and the current gold standards visual perception screening tool.",[54,28],"Stroke","RECRUITING","2024-08-05",{"date":58,"type":34},"2024-08-06",{"date":60,"type":34},"2023-06-20",{"date":62,"type":21},"2026-02-28",{"name":64,"class":41},"Durham University",3]