[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vital-pulp-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vital-pulp-therapy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100562180","comparative-evaluation-of-the-clinical-outcome-of-direct-pulp-capping-treatment-in-permanent-molars-100562180",false,"NCT06599814","Comparative Evaluation of the Clinical Outcome of Direct Pulp Capping Treatment in Permanent Molars","Comparative Evaluation of the Clinical Outcome of Direct Pulp Capping Treatment Using Bioactive Materials With Diode Laser in Permanent Molars: a Randomized Clinical Trial","Inclusion Criteria:\n\n* In all patients, the pulp had been exposed because of caries removal. Data collection included clinical pulp capping respecting the following criteria.\n\nExclusion Criteria:\n\n1. Individuals who are 19 to 40 years old.\n2. Permanent teeth that have not been repaired and have extensive caries on their occlusal and proximal surfaces, extending more than two-thirds of the dentin near the pulp.\n3. Vital teeth; asymptomatic teeth (not sensitive to pressure, percussion, or palpation, and no spontaneous pain); sinus tract devoid of swelling and abscess; abnormal mobility absent; no history of spontaneous pain; mild, dull, and tolerable pain associated with eating and drinking cold drinks.\n4. Ethyl chloride cold tests, gutta-percha heat testing, palpation, percussion, and the lack of radiological symptoms in periapical radiographs are used to assess the life of the teeth prior to treatment. After the stimulus is removed, pain from a pulp test that is triggered by either heat or cold should subside.\n5. In periapical radiography, none of the following conditions should be present: normal lamina dura and periodontal ligaments, no internal or external root resorption, and no radiolucency in the furcation area or periapical region.\n6. The exposed area's diameter ranges from 0.5 to 1 mm.\n7. Participants' acceptance of the research program.",true,"ALL","19 Years","40 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","This clinical trial will be performed during June 2024 and December 2024. The study is conducted following the Declaration of Helsinki Ethical principles for medical research involving human subjects after being independently reviewed and approved by the Institution's Ethical Committee and is designed in accordance with CONSORT 2010.\n\nSelected patients who are between 19 and 40 years of age had undergone conservative treatment for deep caries management in their permanent teeth in the restorative and endodontic departments, faculty of dentistry, Kafrelsheikh university. The patients are then assigned randomly into four different groups for this randomized clinical study. The decision for direct pulp capping will be made after informing the patients about all the pulp capping procedures that are suggested. Furthermore, any possible complications, postoperative discomfort, or failure of the treatment will be discussed with the patient. All included patients signed a written informed consent before enrollment",[28],"Vital Pulp Therapy","RECRUITING","2024-09-13",{"date":32,"type":33},"2024-09-19","ACTUAL",{"date":35,"type":33},"2024-06-01",{"date":37,"type":22},"2025-01-10",{"name":39,"class":40},"Kafrelsheikh University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":41},"100544720","comparative-evaluation-of-melatonin-versus-mta-on-vital-pulp-therapy-in-young-permanent-first-molars-an-in-vivo-study-100544720","NCT06372561","Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study","Comparative Evaluation of Melatonin Versus Mineral Trioxide Aggregate on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study","Inclusion Criteria:\n\n* 1- Apparently healthy and medically free children. 2- Their age ranges from 6-8 years. 3- Both boys and girls will be included. 4- Children should have mandibular permanent first molars with the following clinical and radiographic criteria. 4.1Restorable young permanent first molars. 4.2Absence of clinical evidence of pulp degeneration:\n* No history of spontaneous pain, history of night pain or pain that not relieved by analgesics.\n* No pain on percussion.\n* No mobility.\n* Absence of abscess, purulent sinus or soft tissue edema.\n* Bleeding should stop within 5 minutes after the amputated pulp stumps.\n\nExclusion Criteria:\n\n* Internal root resorption.\n* External root resorption.\n* Inter radicular or periapical bone destruction (radiolucency)\n* A deep carious lesion radiologically that approaches the pulp","6 Years","8 Years",{"count":52,"type":22},45,[25],"The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis. Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts.",[56,28],"Dental Caries in Children","2024-08-01",{"date":59,"type":33},"2024-08-02",{"date":61,"type":33},"2023-05-20",{"date":63,"type":22},"2024-10-02",{"name":65,"class":40},"Suez Canal University"]