[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"vocal-cord-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:vocal-cord-disease":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100639254","ai-assisted-endoscopy-for-upper-aerodigestive-tract-lesions-100639254",false,"NCT07596355","AI-Assisted Endoscopy for Upper Aerodigestive Tract Lesions","Head&Neck Application of Novel Computer-assisted Endoscopy","H&NANCE","Inclusion Criteria:\n\n* Age \\> 18 years\n* Injury originating from the upper aero-digestive tract\n* Recording of the video-endoscopic examination\n* Patient known to undergo a biopsy of the lesion or clinical follow-up for lesion with known biopsy (e.g. laryngeal papillomatosis) or suffering from Reinke's edema (in this pathology, in fact, biopsy is not necessary since the diagnosis is clinical)\n* Or patients undergoing transoral lesion excision\n\nExclusion Criteria:\n\n* Submucosal lesion\n* Patients with previous operations on the upper aero-digestive tract\n* Patients with previous radiotherapy of the head and neck district\n* Poor compliance on endoscopic examination\n* Unavailability of CADe\u002FCADx or CASe data logging note","ALL","18 Years",{"count":20,"type":21},283,"ESTIMATED","OBSERVATIONAL","This is a prospective observational clinical study designed to evaluate the performance of artificial intelligence (AI) algorithms applied to upper aerodigestive tract (UADT) video-endoscopy. The study assesses three main tasks: lesion detection (localization), classification (benign vs malignant), and segmentation of tumor margins.\n\nAI algorithms will be applied to endoscopic video data acquired during routine clinical practice without influencing clinical decision-making. The system will process images in real time and store data for subsequent analysis. AI outputs will be compared with physician assessment and reference standard histopathology to evaluate diagnostic performance.",[25,26,27,28,29,30,31,32,33],"Upper Aerodigestive Tract Neoplasms","Upper AerodigestiveTract Cancer","Upper Aero-digestive Tract (UADT) Neoplasm","Squamous Cell Carcinoma","Leukoplakia","Head and Neck Cancer (H&N)","Vocal Cord Disease","Vocal Fold Polyp","Vocal Fold Nodules","NOT_YET_RECRUITING","2026-05-12",{"date":37,"type":38},"2026-05-19","ACTUAL",{"date":40,"type":21},"2026-05",{"date":42,"type":21},"2028-02",{"name":44,"class":45},"Istituto Italiano di Tecnologia","OTHER",3,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100572569","phase-2-effect-of-superior-laryngeal-nerve-blocks-on-patient-outcomes-in-laryngeal-surgery-100572569","NCT06734975","Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery","Effect of Intraoperative Superior Laryngeal Nerve Blocks on Patient Outcomes in Microdirect Laryngoscopy for Benign Vocal Fold Lesions: A Randomized Trial","Inclusion Criteria:\n\n* Patient is aged 18 years or older at time of consent\n* Patient has suspected or confirmed benign vocal fold lesion\n* Patient is planning to undergo direct laryngoscopy with excision of the vocal fold lesion\n* Patient is English or Spanish speaking\n* Patient is not pregnant per self report\n* Patient is not incarcerated\n\nExclusion Criteria:\n\n* Patient is not 18 years of age or older at consent date\n* Patient does not speak English or Spanish\n* Patient is currently pregnant or plans to become pregnant prior to their study procedure\n* Patient has a laryngeal malignancy or found to find a laryngeal malignancy on final pathology\n* Patient will not be undergoing direct laryngoscopy with excision of lesion\n* Patient is unable to provide consent or complete study activities\n* Patient is incarcerated",{"count":55,"type":21},28,"INTERVENTIONAL",[58],"PHASE2","Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery. Symptoms such as how much coughing or pain patients have after surgery, as well as whether patient's voice gets better will be interrogated.",[31,61,62],"Vocal Cord Polyp","Vocal Cord Cyst","RECRUITING","2026-01-13",{"date":66,"type":38},"2026-01-15",{"date":68,"type":38},"2025-07-11",{"date":70,"type":21},"2026-12",{"name":72,"class":45},"Rutgers, The State University of New Jersey",1]