[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"voice-change\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:voice-change":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,59,88],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":36,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100587890","phorte-therapy-efficacy-in-person-versus-telehealth-100587890",false,"NCT06934265","PhoRTE® Therapy Efficacy: In-Person Versus Telehealth","Phonation Resistance Training Exercises (PhoRTE®) Delivered In-person and Via Telehealth: A Noninferiority Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults 55+ with a primary diagnosis of presbyphonia, age-related voice changes, and\u002For vocal fold atrophy with or without localized loss of lamina propria (e.g. vocal fold scar)\n* Telehealth-capable device (e.g., tablet, computer) with microphone, speaker, camera, high-speed internet\n* Ability to attend four telehealth or in-person sessions for four consecutive sessions\n* Ability to attend two in-person evaluation sessions (pre- and post-treatment)\n\nExclusion Criteria:\n\n* Presence of localized masses, lesions, or vocal fold motion impairments identified during videostroboscopy at initial evaluation\n* Progressive neurologic conditions, e.g. Parkinson's disease (PD), Amyotrophic lateral sclerosis (ALS), Progressive supranuclear palsy (PSP), etc.\n* Previous attendance to exuberant voice therapy (e.g., PhoRTE, Lee Silverman Voice Treatment)\n* Untreated hearing loss\n* Non-English speakers","ALL","54 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study compares how well voice therapy works when delivered in-person versus through telehealth for older adults with age-related voice problems. Researchers are testing whether Phonation Resistance Training Exercises (PhoRTE®) can be just as effective when delivered remotely as when done face-to-face, which could make treatment more accessible and affordable for seniors.\n\nThe two primary hypotheses are:\n\n1. Does voice therapy (called PhoRTE®) work as well through video calls as it does face-to-face?\n2. Can online therapy be a more accessible way for older adults to get help for their voice problems?\n\nAdults aged 55 or older with voice changes and an applicable diagnosis will be randomly assigned to receive either in-person or telehealth therapy, consisting of four 45-minute sessions. After treatment, researchers will measure improvements through:\n\n* Changes in voice function\n* Patient reports about their voice\n* Scientific measurements of voice quality\n* Patient satisfaction with treatment\n* Impact on quality of life\n\nThe results will help determine if telehealth can be a good alternative to in-person voice therapy, especially important as telehealth coverage may be changing.",[26,27,28,29,30,31,32,33,34,35],"Atrophy of Vocal Cord","Presbyphonia","Dysphonia","Glottic Insufficiency","Voice Change","Voice Disorder","Adults","Aging","Speech Therapy","Voice Alteration",[37,38,39,40,41,42,43,44,45],"Vocal fold atrophy","voice therapy","presbyphonia","aging voice","voice rehabilitation","speech pathology","Intervention","voice","aging","NOT_YET_RECRUITING","2026-01-09",{"date":49,"type":50},"2026-01-13","ACTUAL",{"date":52,"type":20},"2026-01-25",{"date":54,"type":20},"2026-10-25",{"name":56,"class":57},"University of Southern California","OTHER",4,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":16,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":4,"studyType":21,"phases":70,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":87},"100516320","effectiveness-of-intraoperative-neuromonitoring-of-external-branch-of-superior-laryngeal-nerve-in-thyroid-surgery-100516320","NCT06002984","Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery","Effectiveness of Intraoperative Neuromonitoring to Identify and Preserve External Branch of Superior Laryngeal Nerve During Thyroid Surgery","Inclusion Criteria:\n\n* Patients who are scheduled to undergo thyroid surgery\n* Patients who understand and agree to take part in this study\n\nExclusion Criteria:\n\n* If the thyroid tumor is suspected to invade adjacent organs (esophagus, trachea, carotid artery, jugular vein etc.)\n* Patients who are required with lateral compartment neck dissection\n* Patients with recurrent thyroid cancer\n* Patients with palsy of recurrent laryngeal nerve or superior laryngeal nerve external branch in the past or present\n* Patients with a history of vocal cord and larynx disease\n* History of hyperthyroidism (e.g., Graves' disease)\n* Taking anticoagulants (aspirin, warfarin, etc.) before surgery\n* Disorders of coagulation\n* In the case of women, pregnant women and breastfeeding patients\n* Patients judged inappropriate by clinical trial researcher","19 Years","79 Years",{"count":69,"type":20},94,[23],"The frequent occurrence of impaired function in the external branch of the superior laryngeal nerves following thyroid surgery is recognized as a prevalent complication leading to a diminished quality of life. The objective of this randomized controlled trial (RCT) is to assess the efficacy of neuromonitoring during thyroid surgery in order to safeguard the integrity of these nerves.",[73,74,30],"Laryngeal Nerve Injuries","Thyroidectomy",[76],"External branch of the superior Laryngeal Nerve","RECRUITING","2025-06-09",{"date":80,"type":50},"2025-06-12",{"date":82,"type":50},"2023-11-24",{"date":84,"type":20},"2026-12-31",{"name":86,"class":57},"Seoul National University Hospital",1,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":92,"acronym":4,"eligibilityCriteria":93,"healthyVolunteers":94,"sex":16,"minAge":95,"maxAge":4,"enrollmentInfo":96,"targetDuration":4,"studyType":21,"phases":98,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":87},"100495567","phase-2-the-use-of-dexamethasone-in-total-thyroidectomy-to-improve-voice-outcome-and-hypocalcaemia-100495567","NCT05732883","The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and Hypocalcaemia","Inclusion Criteria:\n\n* Aged 18 or above\n* Patients undergoing total thyroidectomy for benign pathologies\n* MNG\n* Toxic nodular goitre\n* Graves' disease\n\nExclusion Criteria:\n\n* Non-communicable patients\n* Patients contraindicated for steroid (DM, Hepatitis carrier, Tuberculosis, peptic ulcer disease)\n* Patients contraindicated for analgesics including Panadol, Celebrex, Tramadol or Levobupivacaine\n* Malignant thyroid disease\n* Patients with previous thyroid surgery, or neck surgery\n* Pre-existing hoarseness of voice of any cause or pre-existing vocal cord palsy\n* Pregnancy \u002F Lactating female patients\n* Pre-existing renal disease \u002F autoimmune disease on steroids\n* Patients who require steroid cover during operation e.g. hydrocortisone perioperatively",true,"18 Years",{"count":97,"type":20},100,[99],"PHASE2","Thyroidectomy is a standard procedure for benign and malignant pathologies of the thyroid gland. Each year, some 100 total thyroidectomies are performed in Kowloon East Cluster, Hospital Authority, Hong Kong. Total thyroidectomy is associated with voice dysfunction and temporary hypocalcaemia in up to 80% and 50%, respectively. Previous study from our institute showed a 3% rate of permanent vocal cord palsy and 16% of permanent hypoparathyroidism requiring calcium and\u002For vitamin D supplements. The use of dexamethasone has been studied in the past in total thyroidectomy patients and has been shown to be safe and effective in improving post-operative nausea and vomiting. No complications or drug related side effects were associated with a single dose of steroid. Recent studies have also shown that Dexamethasone is effective in improving voice outcome and hypocalcaemia in thyroidectomy patients. The investigators aim to study the effect of Dexamethasone in post-operative voice outcome and hypocalcaemia. Objective assessment of the vocal cords during phonation will be performed pre-operative and post-operatively. Serum Calcium level will be monitored.",[30,102],"Hypocalcemia",[104,105,106,102,107,74,108,109],"Voice dysfunction","Hoarseness of Voice","Vocal cord palsy","Hypoparathyroidism","Dexamethasone","Steroid","2024-07-06",{"date":112,"type":50},"2024-07-09",{"date":114,"type":50},"2024-07-01",{"date":116,"type":20},"2026-09-30",{"name":118,"class":57},"Tseung Kwan O Hospital, Hong Kong"]