[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"voice-fatigue\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:voice-fatigue":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100621494","effects-of-emst-and-triflo-on-voice-parameters-and-vocal-fatigue-100621494",false,"NCT07371351","\"Effects of EMST and Triflo on Voice Parameters and Vocal Fatigue\"","The Effect of EMST and Triflo Devices on Acoustic and Aerodynamic Parameters of Sound and Sound Fatigue in Academics: A Randomized Controlled Study","Inclusion Criteria:\n\nHaving taught for at least 2 academic semesters as an academic. Having taught at least 9 hours of face-to-face classes per week. Not having been diagnosed with an organic voice disorder. Not smoking. Not being in a menstrual cycle during the pre-, mid- and post-tests.\n\nExclusion Criteria:\n\nBeing Pregnancy, hypertension disease have a history of stroke, heart anomaly disease chronic asthma disease emphysema or obstructive pulmonary disease, have a any surgery in the skull base and neck region, have a any neurogenic or psychological diagnosis or condition.",true,"ALL","25 Years","55 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","A healthy voice is essential for meeting professional and communicative demands, particularly for professional voice users such as academics, who are at increased risk of voice disorders due to prolonged and intensive voice use, unfavorable acoustic conditions, and stress. Voice disorders often result from inadequate respiratory support, leading to compensatory laryngeal overuse, vocal fatigue, and deterioration in voice quality. Although traditional voice therapy emphasizes diaphragmatic breathing, it does not enhance respiratory capacity because it lacks resistance. This study aims to investigate the effects of resistance-based breathing exercises using the Expiratory Muscle Strength Trainer (EMST 150) and triflo devices on respiratory capacity, acoustic and aerodynamic voice parameters, and vocal fatigue in academics. The findings are expected to contribute to the literature and support the use of EMST as a preventive and therapeutic approach for occupational groups at risk of voice disorders.",[28,29,30,31,32],"Voice Fatigue","Voice Disorder","Academic Voice Use and Voice Fatigue","Academician's Risk of Developing Voice Disorder","Voice Disorder Prevention in Academics",[34,35,36,37,38],"Voice Disorders","Vocal Fatigue","Professional Voice Users","Respiratory Muscle Training","Acoustic Analysis","NOT_YET_RECRUITING","2026-01-19",{"date":42,"type":43},"2026-01-27","ACTUAL",{"date":45,"type":22},"2026-01-10",{"date":47,"type":22},"2026-05-10",{"name":49,"class":50},"Medipol University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":16,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":23,"phases":65,"briefSummary":66,"conditions":67,"keywords":68,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":51},"100525814","brain-and-voice-signatures-in-teachers-100525814","NCT06126627","Brain and Voice Signatures in Teachers","Neurobiological and Psychobiological Signatures of Vocal Effort in Early Career Teachers","BRAVO1","Inclusion Criteria:\n\nTeachers (max. 10 years full-time) or student teachers in good health between 21 and 39 years with symptoms of vocal fatigue.\n\nControl participants in good health between 21 and 39 years without symptoms of vocal fatigue.\n\nExclusion Criteria:\n\n* Lefthandedness\n* Smoking (past 5 years)\n* Known changes of the vocal folds (e.g., vocal fold nodules), vocal fold paralysis, surgeries on the larynx or thryoid or current organic or neurological changes of the vocal folds or vocal function per videoendoscopy and -stroboscopy of the larynx\n* History of voice therapy\n* Hoarseness\n* Respiratory illness, allergies (respiratory, silver), reflux or asthma at time of participation\n* Hearing disorder or hearing aids\n* Psychological, neurological or endocrinological disorders\n* Psychotropic or steorid medications\n* Body mass index \\> 30\n* Indications against MRI such as metail parts in or on the body (e.g., permanent dental prostheses or braces, screws, prostheses, piercings or large tattoos\n* Nearsightedness \\> -5 diopters, if only glasses are worn\n* Claustrophobia\n* Pregnancy","FEMALE","21 Years","39 Years",{"count":64,"type":22},100,[25],"Primary muscle tension dysphonia voice disorder with symptoms of vocal strain and vocal fatigue is common and can have a significant negative impact on quality of Life. Yet, primary muscle tension dysphonia's causes are unknown precluding precise diagnostic classification. Stress and personality are thought to play a role and thus, the project aims to determine the practical and clinical effect of stress on the control of voice and speech in the brain. Participants are female early career teachers and student teachers with symptoms of vocal fatigue, as well as control participants without vocal fatigue, who perform speech tasks on two different occasions. Neural (imaging of brain), psychobiological (saliva, personality), and voice and speech (muscle activity of voice muscles on the neck with surface sensors, audio recordings) data will compare reactivity patterns of teachers who are stressresponders with those who are nonresponders as well as control participants. The central hypothesis is that voice box stress responders have heightened emotion-motor activations involving the emotional voice production pathway, which correlate with changes in voice muscle activity in the anterior neck. The results will provide fundamentally missing data in our understanding of the role of stress in vocal complaints and will yield new insights about the neural underpinnings of primary muscle tension dysphonia. The study findings will have a significant impact on how clinicians identify so-called laryngoresponders to help them prevent voice disorders.",[34,28],[69,70,71,72,73,74,75,76,77],"voice disorders","vocal fatigue","occupational voice disorders","stress reactivity","vocal control","laryngeal motor cortex","teachers","speech motor control","voice motor control","RECRUITING","2025-08-20",{"date":81,"type":43},"2025-08-27",{"date":83,"type":43},"2023-08-01",{"date":85,"type":22},"2026-07-31",{"name":87,"class":50},"University Hospital, Bonn"]