[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"walking\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:walking":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,52,82,119,153,188,222],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100641589","effects-of-a-powered-lower-limb-exoskeleton-on-walking-performance-in-older-adults-100641589",false,"NCT07633093","Effects of a Powered Lower-Limb Exoskeleton on Walking Performance in Older Adults","Acute Effects of a Powered Lower-Limb Exoskeleton on Walking Performance in Community-Dwelling Older Adults: A Randomized Crossover Trial","E-WALK","Inclusion Criteria:\n\n* Older adults aged 65 to 75 years who are community-dwelling, independently ambulatory, able to walk independently on level ground, able to maintain standing balance without personal assistance, and able to understand study instructions.\n* Young-adult reference participants aged 18 to 22 years who are healthy university students without known conditions affecting walking or balance.\n\nExclusion Criteria:\n\n* Self-reported neurological disease affecting gait or balance.\n* Major musculoskeletal injury or surgery affecting walking within the previous 6 months.\n* Uncontrolled cardiopulmonary disease.\n* Severe visual or vestibular impairment affecting safe walking.\n* Current lower-limb pain that limits walking.\n* Cognitive impairment that prevents informed consent or protocol adherence.\n* Any condition judged by the study team to make participation unsafe.",true,"ALL","18 Years","75 Years",{"count":22,"type":23},40,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this clinical trial is to learn whether a powered wearable lower-limb exoskeleton can improve walking performance in independently ambulatory older adults aged 65 to 75 years.\n\nThe main questions it aims to answer are:\n\n* Does use of a powered lower-limb exoskeleton increase comfortable walking speed over 10 meters?\n* Does use of a powered lower-limb exoskeleton increase average walking speed during a 400-meter walk?\n\nResearchers will compare walking performance in older adults during walking with the powered exoskeleton and walking without the device to determine whether the exoskeleton improves mobility. Young-adult reference participants will also complete walking assessments to provide reference values for walking performance.\n\nParticipants will:\n\n* Attend a screening and familiarization visit.\n* Complete walking assessments with and without the powered exoskeleton in randomized order (older adults only).\n* Perform a 10-meter walk test, a 400-meter walk test, and other physical performance assessments.\n* Complete questionnaires about balance confidence, fear of falling, and device usability.\n* Be monitored for safety events during testing.",[29,30,31,32],"Aging","Walking","Physical Function","Mobility Limitation",[34,35,36,37,38],"Exoskeleton","Wearable Robotics","Gait Speed","Assistive Technology","Mobility Assistance","RECRUITING","2026-06-18",{"date":42,"type":43},"2026-06-22","ACTUAL",{"date":45,"type":23},"2026-07-01",{"date":47,"type":23},"2026-10-01",{"name":49,"class":50},"Hunan Normal University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100642517","balance-fall-risk-and-gait-in-women-with-total-knee-arthroplasty-100642517","NCT07650175","Balance, Fall Risk, and Gait in Women With Total Knee Arthroplasty","Investigation of Balance, Fall Risk, Gait Performance, and Quality of Life in Postmenopausal Women Undergoing Total Knee Arthroplasty","Inclusion Criteria:\n\n* Volunteering to participate in the study.\n* Being 60 years of age or older.\n* Having a Mini Mental Test score of 24 or higher.\n* Not having undergone previous arthroplasty surgery on the knee where surgery is planned.\n* Having experienced unilateral TDA.\n* Being a postmenopausal woman\n\nExclusion Criteria:\n\n* Individuals whose vital signs are unstable after surgery, or who develop any major complications such as deep vein thrombosis, pulmonary embolism, wound infection, or prolonged anesthesia side effects.\n* Presence of any neurological, vestibular, visual, cardiopulmonary, auditory, or cognitive deficits that may affect measurements.\n* Individuals diagnosed with diabetes.","FEMALE","60 Years","85 Years",{"count":63,"type":23},30,"OBSERVATIONAL","Total knee arthroplasty (TKA) is a commonly performed surgical procedure aimed at reducing pain, restoring joint function, and improving quality of life, particularly among older women. Despite improvements in pain and functional outcomes following TKA, findings regarding balance, fall risk, and gait performance remain inconsistent. Impairments in these parameters may adversely affect daily activities, independence, and overall quality of life.\n\nUnlike previous studies that have primarily focused on one or two outcomes, this study will comprehensively evaluate balance, fall risk, gait performance, and quality of life in postmenopausal women who have undergone TKA. The findings are expected to provide a more holistic understanding of long-term functional outcomes following TKA and contribute to the planning of rehabilitation programs. Therefore, the aim of this study is to compare balance, fall risk, gait performance, and quality of life between postmenopausal women who have undergone TKA and healthy postmenopausal women.",[67,68,69,70,71,30],"Total Knee Arthroplasty","Postmenopausal Women","Quality of Life (QOL)","Balance","Risk of Falling","NOT_YET_RECRUITING","2026-06-10",{"date":75,"type":43},"2026-06-16",{"date":77,"type":23},"2026-06-20",{"date":79,"type":23},"2026-07-22",{"name":81,"class":50},"Karabuk University",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":17,"sex":18,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":24,"phases":94,"briefSummary":95,"conditions":96,"keywords":102,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":51},"100636793","promoting-walking-among-older-adults-through-affective-communication-and-step-monitoring-100636793","NCT07570303","Promoting Walking Among Older Adults Through Affective Communication and Step-Monitoring","Self-Continuity Messages and Step-Monitoring to Promote Walking Among Older Adults: Protocol of a 4-Arm Randomised Controlled Trial","NOSTEP","Inclusion Criteria:\n\n* Age between 65 and 74 years\n* Willingness and ability to install and use the mobile applications required for study participation\n* Sufficient proficiency in the Italian language to understand study materials and complete the questionnaires.\n\nExclusion Criteria:\n\n\\- Physical disabilities or medical conditions that preclude engagement in light to moderate physical activity, specifically:\n\n1. medical advice or prescription prohibiting engagement in light to moderate physical activity, assessed via a close-ended screening question;\n2. positive screening on a study specific close-ended question assessing ability to perform physical activity;\n3. positive screening on the adapted revised Physical Activity Readiness Questionnaire (rPAR-Q), indicating that participant may be unsafe.","65 Years","74 Years",{"count":93,"type":23},1000,[26],"Physical inactivity increases substantially after age 60 and represents a major public health challenge in older adults, as it is linked to increased risk of functional and cognitive decline and aging problems. Walking is one of the most accessible and recommended forms of light-to-moderate physical activity for this population. However, promoting sustained engagement in walking remains difficult, as traditional informational approaches often fail to activate personally meaningful motivations.\n\nThis study tests whether persuasive affective messages can promote walking by leveraging self-continuity, meaning the use of autobiographical memory to maintain the sense of being the same person across time and contexts, connecting the past, present, and future self. Self-continuity is associated with psychological resources such as self-esteem, self-efficacy, and a sense of meaning in life. The affective mechanism that sustains self-continuity is nostalgia: both promote emotional and behavioral regulation and support goal achievement. Building on this framework, the present trial examines whether activating feelings of self-continuity and positive nostalgic memories can strengthen older adults' motivation to engage in walking behavior.\n\nIn addition, the study investigates whether combining self-continuity messaging with a self-regulation strategy (daily step monitoring) enhances intervention effectiveness. Self-monitoring is a well-established behavioral technique that supports goal pursuit by increasing awareness and feedback.\n\nUsing a 4-arm randomised controlled factorial design, the study compares the effects of self-continuity messages, step-monitoring reminders, their combination, and an active control condition on walking behaviour and its psychological determinants.\n\nA national sample of 1,000 Italian adults aged 65-74, recruited through a certified panel provider (Ipsos) and balanced for age, gender, and geographic region, will be randomly assigned to one of the four conditions. All participants will receive one message per day through a mobile application over a 14-day period. Participants in the step-monitoring conditions will also be asked to track and report their daily step count using a pedometer application. Behavioral, psychological, and process measures will be collected at baseline, post-intervention, and follow-up.\n\nThe study therefore aims to provide experimental evidence on the role of self-continuity as a motivational driver of health behaviour change, and to clarify whether combining affective and self-regulatory strategies enhances intervention effectiveness in older adults.",[30,97,98,99,100,101],"Older Adults (65 Years and Older)","Messaging","Mobile Applications","Psychosocial Factors","Health Behaviour",[103,104,105,106,107,108,109,110],"health behaviour change","physical activity","walking","older adults","persuasive communication","messages","self-monitoring","self-continuity",{"date":112,"type":43},"2026-06-12",{"date":114,"type":23},"2026-06",{"date":116,"type":23},"2026-08",{"name":118,"class":50},"Catholic University, Italy",{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":125,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":24,"phases":129,"briefSummary":130,"conditions":131,"keywords":139,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":51},"100640010","mobile-dual-task-brain-and-balance-intervention-for-concussion-recovery-100640010","NCT07599475","Mobile Dual-Task Brain and Balance Intervention for Concussion Recovery","Boosting Brain and Balance: A Mobile Dual-Task Intervention for Athletes With Concussion and Mild Traumatic Brain Injury (mTBI)","Inclusion Criteria:\n\n* Adults aged 18 to 40 years\n* Self-reported history of sports-related concussion (SRC) or mild traumatic brain injury (mTBI) within the past 3 to 12 months\n* Meets criteria for mTBI based on a standardized screening method (e.g., Ohio State University TBI Identification Method)\n* Able to safely participate in light physical activity (e.g., walking) and simple cognitive tasks based on self-report and observational screening by the research team\n* Able to read and understand English (if applicable for study materials)\n* Able to provide informed consent\n* Has access to and is able to use a smartphone or mobile device to complete daily app-based activities\n\nExclusion Criteria:\n\n* Age younger than 18 years or older than 40 years\n* History of moderate or severe traumatic brain injury\n* Concussion or mTBI occurring less than 3 months or more than 12 months prior to enrollment\n* Self-reported active medical disease or history of neurological or psychiatric conditions unrelated to concussion\n* Self-reported other medical conditions that would limit safe participation in light physical activity (e.g., walking or balance tasks)\n* Currently on prescribed medications that may significantly affect cognitive function, balance, neurological function, or safe participation in light physical activity\n* Inability to use a smartphone or mobile device required for study participation\n* Inability to read or understand English (as study materials and the mobile application are currently available only in English)","40 Years",{"count":128,"type":23},20,[26],"This research study examines recovery after a sports-related concussion or mild head injury. Many athletes experience lingering problems with thinking, balance, and mood months after a concussion.\n\nWe are testing a new home-based program called BraW-Day™ (Brain \\& Walk Exercise Every Day). This 14-day program uses a mobile app on your smartphone and combines simple brain exercises (like counting backwards) with walking exercises. The idea is that doing these tasks together may help your brain and body recover more effectively.\n\nWhat You'll Do:\n\n* Two in-person visits at UNLV (baseline and after 14 days) for assessments\n* Daily 15-minute exercises at home using the BraW-Day app\n* Provide a small saliva sample for biomarker testing\n* Complete brief questionnaires about your symptoms and health\n\nPotential Benefits:\n\nYou may experience improvements in thinking, balance, or mood. Even if you don't benefit directly, your participation will help researchers understand how to better support athletes recovering from concussion.\n\nWho Can Join:\n\n* Ages 18-40\n* Had a sports-related concussion or mild head injury within the past 3-12 months\n* Have a smartphone and can safely do light walking and simple tasks\n\nThis study is registered at ClinicalTrials.gov and approved by the UNLV Institutional Review Board to protect your safety and rights.",[132,133,134,30,135,136,137,138],"Mild Traumatic Brain Injury (mTBI)","Sports-related Concussion","Heart Rate Variability (HRV)","Oculomotor","Saliva","Exosomal microRNA","Cognitive Function",[140,141,142,143],"dual-task","mild traumatic brain injury (mTBI)","sports-related concussion","BraW-Day","2026-05-14",{"date":146,"type":43},"2026-05-20",{"date":148,"type":23},"2026-05-15",{"date":150,"type":23},"2027-04-30",{"name":152,"class":50},"Hyunhwa Lee",{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":159,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":24,"phases":163,"briefSummary":164,"conditions":165,"keywords":174,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":4},"100631702","the-effect-of-remotely-delivered-pilates-on-physical--and-psychological-outcomes-in-individuals-with-multiple-sclerosis-100631702","NCT07504120","The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis","Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?","MS","Inclusion Criteria:\n\n* Age 18 years or older\n* Self-reported diagnosis of multiple sclerosis by a neurologist\n* Relapse-free for the past 30 days before screening\n* Able to speak and read English as the primary language\n* Access to the internet and e-mail,\n* Ability to use Zoom, and willingness to complete testing sessions and questionnaires\n* Ambulatory without an assistive device (for example, cane)\n* Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS)\n* Insufficiently active, defined as a score \\\u003C 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS)\n* Adequate visual ability and literacy to read materials printed in 14-point font\n* Currently treated with a disease-modifying therapy\n\nExclusion Criteria:\n\n* Pregnant\n* Elevated risk for strenuous or maximal exercise, defined as more than one \"Yes\" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening",{"count":162,"type":23},50,[26],"Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.\n\nObjective 2: To examine the impact of a 16-week remotely delivered Pilates intervention on depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.\n\nAim Aim 1: To assess whether the 16-week remotely delivered Pilates intervention significantly improves walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS Aim 2: To investigate whether the 16-week remotely delivered Pilates intervention significantly improves depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.\n\nHypothesis Hypothesis 1: The 16-week remotely delivered Pilates intervention will significantly improve walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.\n\nHypothesis 2: Participants receiving the 16-week remotely delivered Pilates intervention will demonstrate significantly greater improvements in depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.",[166,167,30,70,168,169,170,171,172,173],"Multiple Sclerosis","Pilates Exercise","Fatigue in Multiple Sclerosis","Pain Management","Quality of Life","Depression","Cognition","Fatigue",[175,176,173,172,177,30,171,70,178],"multiple sclerosis","Pilates","Quality of life","Pain","2026-03-25",{"date":181,"type":43},"2026-03-31",{"date":183,"type":23},"2026-06-01",{"date":185,"type":23},"2027-12-01",{"name":187,"class":50},"University of Illinois at Chicago",{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":18,"minAge":196,"maxAge":4,"enrollmentInfo":197,"targetDuration":4,"studyType":24,"phases":199,"briefSummary":200,"conditions":201,"keywords":203,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":51},"100618651","impact-of-a-multicomponent-exercise-program-on-cognitive-and-functional-outcomes-in-patients-with-mild-cognitive-impairment-100618651","NCT07334392","Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment","Effectiveness of an Innovative Therapeutic Exercise Program on Physical and Cognitive Function in Mild Cognitive Impairment Due to Alzheimer's Disease","MExeProMCI","Inclusion Criteria:\n\n* individuals \\> 50 years old\n* people with confirmed cognitive impairment, as evidenced by values within normal limits on the Montreal Cognitive Assessment test (MOCA ) \\>20\n* stable medication in the last month\n* independent walking\n\nExclusion Criteria:\n\n* people with dementia\n* people suffering from chronic mental illness (e.g. schizophrenia, bipolar disorder)\n* people suffering from a neurological disorder or injuries (e.g. multiple sclerosis, Parkinson's, traumatic brain injury)\n* people with clinical depression (as determined by the Neuropsychiatric Inventory (NPI) assessment and medical diagnosis)\n* people who have had recent surgery\n* people with insufficient knowledge of the Greek language","50 Years",{"count":198,"type":23},45,[26],"The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment. The main questions it aims to answer are:\n\nDoes the innovative therapeutic exercise program improve gait and balance? Does the innovative therapeutic exercise program improve cognition?\n\nResearchers will compare the innovative therapeutic exercise program emphasizing in dual-task exercises to a therapeutic exercise program without emphasizing in dual-task exercises and to a control group (given instruction about the benefits of exercise).\n\nParticipants will:\n\n* Perform the exercise program twice a week for three months.\n* Will be assessed before and after the intervention.\n* Will record The Borg Scale of Perceived Exertion every second week to monitor and assess the progression of exercise intensity.",[202,30,70,172],"Mild Cognitive Impairment",[204,205,206,207,208,209,210,211,212],"kinetic and kinematic","balance","global cognition","executive function","attention","mci","multicomponent program","exercise","dual tasking","2025-12-30",{"date":215,"type":43},"2026-01-12",{"date":217,"type":43},"2025-12-01",{"date":219,"type":23},"2026-11-30",{"name":221,"class":50},"University of Patras",{"id":223,"slug":224,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":11,"sex":18,"minAge":229,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":24,"phases":232,"briefSummary":233,"conditions":234,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":51},"100600364","effectiveness-of-suit-therapy-with-dual-task-exercises-on-gross-motor-functions-and-walking-in-children-with-diplegic-cerebral-palsy-100600364","NCT07096531","Effectiveness of Suit Therapy With Dual Task Exercises on Gross Motor Functions and Walking in Children With Diplegic Cerebral Palsy","The Effectiveness of Suit Therapy With Dual Task Exercises on Gross Motor Functions and Walking in Children With Diplegic Cerebral Palsy","Inclusion Criteria:\n\n* Age from 6 to 12 years.\n* Both sexes.\n* A medical diagnosis of spastic diplegic CP made by pediatricians or pediatric neurologists.\n* Children with spasticity grades ranged from 1 to 2+ according to the Modified Ashworth scale (MAS).\n* Children who can sit on the chair with good balance and recognize and follow verbal orders and commands are included in both testing and training techniques.\n\nExclusion Criteria:\n\n* They had a permanent deformity (bony or soft tissue contractures).\n* Children having visual or auditory defects.\n* Current hospitalization for urgent medical reasons.\n* Severe mental retardation.\n* Children who will undergo fewer than twelve regular sessions of physical therapy at their place will not be included in the survey.\n* Children with a history of epileptic seizure or any diagnosed cardiac or orthopedic disability that may hinder assessment methods and treatment.","6 Years","12 Years",{"count":63,"type":23},[26],"This study aims to investigate the effect of suit therapy combined with dual-task training on gross motor performance and walking abilities in children with diplegic cerebral palsy.",[235,236,237,30,238,239],"Suit Therapy","Dual Task Exercises","Gross Motor Functions","Children","Diplegic Cerebral Palsy","2025-07-24",{"date":242,"type":43},"2025-07-31",{"date":244,"type":43},"2023-10-01",{"date":246,"type":23},"2025-09-30",{"name":248,"class":50},"Kafrelsheikh University"]