[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"warts-of-foot\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:warts-of-foot":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,56],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":33,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":5},"100627454","phase-4-intralesional-therapies-for-cutaneous-viral-warts-a-comparative-analysis-of-vitamin-d3-and-acyclovir-100627454",false,"NCT07448844","Intralesional Therapies For Cutaneous Viral Warts: A Comparative Analysis Of Vitamin D3 And Acyclovir","Inclusion Criteria:\n\n* Patients aged 12 years and above with clinically diagnosed cutaneous warts\n* Common, plantar, flat, or periungual warts\n* Both treatment-naïve patients and those with recalcitrant warts\n\nExclusion Criteria:\n\n* Pregnant or lactating women\n* Immunocompromised patients\n* Individuals with history of hypersensitivity to vitamin D3 or acyclovir\n* Individuals receiving systemic immunosuppressive or antiviral therapy\n* Patients with secondary infection at injection site\n* Patients who had received any topical or destructive treatment for wart in previous three months","ALL","12 Years",{"count":18,"type":19},40,"ESTIMATED","INTERVENTIONAL",[22],"PHASE4","The goal of this clinical trial is to learn if injecting acyclovir (an antiviral drug) or vitamin D3 directly into skin warts works to clear them in people aged 12 and older with common, plantar, flat, or periungual (around the nail) warts. The main questions it aims to answer are:\n\n1. Does intralesional acyclovir or vitamin D3 lead to complete clearance of warts by week 8?\n2. Which treatment clears warts more effectively?\n3. What side effects do participants have with each treatment?\n\nResearchers will compare acyclovir injections (Group A) to vitamin D3 injections (Group B), with 20 participants in each group, to see which treatment works better at clearing warts.\n\nParticipants will:\n\n1. Receive an injection directly into the wart every 2 weeks for up to 4 sessions\n2. Have photographs taken of their warts before treatment and at each visit\n3. Visit the clinic for checkups where the size and number of warts will be measured\n4. Be followed for up to 3 months to check for wart recurrence and side effects",[25,26,27,28,29,30,31,32],"Viral Wart","Plantar Wart","Common Warts (Verruca Vulgaris)","Common Wart","Flat Wart","Warts of Foot","Warts Hand","Wart",[34,35,36,37,38,39,40,41,42,43],"Cutaneous warts","intralesional therapy","treatment efficacy","plantar warts","common warts","human papillomavirus","randomized controlled trial","vitamin D3","acyclovir","flat warts","RECRUITING","2026-03-06",{"date":47,"type":48},"2026-03-10","ACTUAL",{"date":50,"type":48},"2026-02-20",{"date":52,"type":19},"2026-05-20",{"name":54,"class":55},"Riphah International University","OTHER",{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":37,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":15,"minAge":63,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":20,"phases":66,"briefSummary":68,"conditions":69,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100596153","microneedling-alone-versus-microneedling-coupled-with-either-bleomycin-or-5flourouracil-in-the-treatment-of-plantar-warts-100596153","NCT07041749","Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar Warts","Comparison of the Efficacy of Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar Warts","Inclusion Criteria:\n\n\\-\n\nExclusion Criteria:\n\n\\- 1. Children below 18. 2.Pregnant and lactating women. 3.Patients with any systemic disease or immunocompromised Patients or patients receiving any immunosuppressive drugs.\n\n4\\. Impaired wound healing or imunosuppresion. 5.Patients who received any treatment for warts in the last month before study.","18 Years",{"count":65,"type":19},60,[67],"NA","To compare between the efficacy and safety of microneedling alone, microneedling with topical bleomycin and microneedling with 5-flurouracil in treatment of planter warts.\n\nMicroneedling will be performed on each wart using dermapen supplied with 12 needles arranged in rows. Topical anesthetic cream will be applied for 60 min before the procedures. Microneedling will be performed on each wart using dermapen. The penetration depth will be adjusted at 2-mm, endpoint is pinpoint bleeding and the dermapen will be held by the hand in a vertical direction on the warts.\n\nBleomycin is typically supplied in 15 U vials. The preparation will be diluted first with 7 mL normal saline ,double the amount taken from the vial by adding the same amount lidocaine (2%), so that the concentrations become 1 U\u002FmL . The maximum total amount of bleomycin taken to each patient in one session will be 1 U\u002F1 mL . Microneedling will be performed on the lesion using a microneedling pen type device with a 1-cm tip diameter at a 2-mm depth setting for 2-3 minutes until pinpoint bleebing occurs 1 mL of the prepared solution of bleomycin (1 U\u002F1 mL) will be dropped on to the wart tissue using insulin syringe and occlusion will be applied for 3 hours.\n\n5-FU is available in 10 mL vial: 500 mg\u002F10 mL. Application of 5-FU solution will be done by dropping using an insulin syringe (1 mL)to help dropping of the solution on the warts surface. Then, the lesion will be occluded with a plaster for 3 h.\n\nSessions: Sessions will be performed every 2 weeks until complete cure or for maximum 6 sessions (total 3 month)",[30],"NOT_YET_RECRUITING","2025-06-26",{"date":73,"type":48},"2025-06-27",{"date":75,"type":19},"2026-06-01",{"date":77,"type":19},"2027-07-01",{"name":79,"class":55},"Assiut University"]