[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wear-comfort\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wear-comfort":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":24,"studyType":25,"phases":4,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100611108","3d-printed-vs-milled-occlusal-splints-in-dentistry-100611108",false,"NCT07236294","3D Printed vs. Milled Occlusal Splints in Dentistry","Material and Clinical Assessment of 3D-printed vs. Milled Occlusal Splints: A Study on Performance and Durability in Dental Applications","Splints","Inclusion Criteria:\n\n* Subjects being healthy (ASA \\\u003CIV)\n* Subjects with healthy, complete dentitions (except for extractions of wisdom teeth, or tooth extractions for the purpose of orthodontic treatment in the past)\n* Subjects willing and able to participate in the study\n* Subjects willing to provide written informed consent for their participation in the study\n\nExclusion Criteria:\n\n* Subjects with dental issues other than the inclusion criteria\n* Subjects with a history of autoimmune disorder\n* Subjects with known allergies to acrylic materials\n* Subjects with severe allergies manifested by a history of anaphylaxis or those with severe, chronic allergies (e.g., asthma) and subjects with an active infection of any kind at the time of enrollment\n* Subjects who are pregnant or lactating\n* Subjects enrolled in another investigational clinical trial",true,"ALL","18 Years","45 Years",{"count":22,"type":23},24,"ESTIMATED","6 Weeks","OBSERVATIONAL","This crossover study aims to evaluate the wear comfort, retention, and stability of 3D-printed and milled occlusal splints in healthy subjects.\n\nThe main question it aims to answer is:\n\nResearch questions\n\n\\- How do healthy subjects experience the wear comfort, fitting, retention and stability of a printed and milled occlusal splint? and how do clinicians experience the fitting, retention and stability of the splints?\n\nBy systematically assessing self-reported outcomes, this research seeks to contribute valuable insights into the practical applications of both technologies. The findings may not only enhance our understanding of patient preferences but also guide future developments in the design and manufacturing of occlusal splints, ultimately improving patient care in dental practice.",[28,29,30],"Wear Comfort","Retention","Stability",[32,33,34,29,30,35],"3D printed splints","Milled splints","Prospective clinical randomized crossover study","comfort","NOT_YET_RECRUITING","2025-11-14",{"date":39,"type":40},"2025-11-19","ACTUAL",{"date":42,"type":23},"2026-01-01",{"date":44,"type":23},"2026-09-01",{"name":46,"class":47},"Radboud University Medical Center","OTHER"]