[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"weight-regain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:weight-regain":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,51,79,102,125],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100644753","time-restricted-eating-after-bariatric-surgery-100644753",false,"NCT07672821","Time-Restricted Eating After Bariatric Surgery","Comparison of Time-Restricted Intermittent Fasting Diet in Individuals With and Without Bariatric Surgery","Inclusion Criteria:\n\n* Adults aged 18-65 years with obesity who have not undergone bariatric surgery\n* Adults aged 18-65 years with obesity who have undergone bariatric surgery and experienced insufficient weight loss (IWL) within 18 months post-surgery, -defined as %EWL \\\u003C50% at 18 months\n* Adults aged 18-65 years with obesity who have undergone bariatric surgery and experienced weight regain (WR), defined as \\>25% increase in %EWL from the lowest recorded weight\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding individuals\n* Acute illness, active infection, or comorbid conditions limiting treatment efficacy and safety, including: cancer, type 1 diabetes, renal or hepatic failure, recent stroke or myocardial infarction, nephrolithiasis, drug or alcohol abuse, eating disorders, severe depression or other psychiatric disorders, inflammatory bowel disease (IBD), neoplasia, arrhythmic heart disease, heart failure, respiratory failure, or corticosteroid therapy\n* Professional athletes","ALL","18 Years","65 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the effects of time-restricted eating (TRE, 16\u002F8) in adults with obesity who have and have not undergone bariatric surgery (BS). The study will include adults aged 18-65 years: those with obesity who have not undergone BS, and those who have experienced insufficient weight loss (IWL) or weight regain (WR) following BS. Both groups will follow a 16:8 time-restricted eating protocol for 6 weeks, with an 8-hour eating window recommended between 10:00 AM and 6:00 PM, though participants may adjust to other 16-hour fasting windows. Participants will be evaluated before and after the intervention in terms of anthropometric measurements, biochemical parameters, and dietary habits. The study is being conducted at a private hospital in Bursa, Turkey, and is planned to be completed with a total of 40 participants (20 per group).",[27,28,29,30,31],"Obesity & Overweight","Bariatric Surgery","Weight Regain","Weight Regain Post Bariatric Surgery","Time Restricted Feeding",[33,34,28,35,29,36,37],"Time-Restricted Eating","Intermittent Fasting","Obesity","Anthropometric Measurements","Nutritional Assessment","RECRUITING","2026-06-26",{"date":41,"type":42},"2026-06-29","ACTUAL",{"date":44,"type":42},"2025-07-12",{"date":46,"type":21},"2026-07-12",{"name":48,"class":49},"Medipol University","OTHER",2,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":78},"100594129","randomized-study-on-transoral-outlet-reduction-and-lifestyle-changes-for-weight-regain-after-gastric-bypass-100594129","NCT07015424","Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass","Prospective, Randomized Clinical Study Evaluating Transoral Outlet Reduction (TORe) and Lifestyle Modification for Patients With Weight Regain Following Roux-en-Y Gastric Bypass","REIGNITE","Inclusion Criteria:\n\n* 18 years or older.\n* Experiencing weight regain (≥ 20% weight from nadir) after achieving clinically successful weight loss.\n* Willing to have a TORe procedure for the treatment of weight regain.\n* BMI between 30 and 50 kg\u002Fm2, inclusive.\n* GJA diameter ≥ 20 mm, confirmed either during a\n* Screening EGD completed ≤ 60 days from study procedure or\n* EGD performed immediately prior to the TORe procedure.\n* Anatomically accepting of the procedure, including a pouch size that will not require reduction at the time of treatment (pouch that is shorter than 6 cm in length).\n* Agrees not to take additional over the counter or prescribed weight loss supplements \u002F medications (including incretins) during the first 6 months of the study.\n* Is on a stable dose of anti-diabetic medication for three months with no anticipated changes during the first 6 months of the study.\n* Agrees to the follow-up requirements of the study and is able to read, understand, and sign a written Informed Consent Form to participate in the study.\n* Meets the indications for TORe procedure with OverStitch™ Endoscopic Suturing System.\n\nExclusion Criteria:\n\n* Current use or use within the three months prior to the baseline visit of over the counter or prescribed weight loss supplements \u002F medications (including incretins).\n* Current or planned management of Type 2 Diabetes with incretin medications.\n* Inability or unwillingness to comply with assigned treatment or protocol requirements related to visits.\n* Investigator's medical judgement that the subject is not a candidate for the TORe procedure.\n* Current pregnancy confirmed by site standard of care or planned pregnancy or breastfeeding in the next two years.\n* Vulnerable subject.",{"count":60,"type":21},108,[24],"The goal of this clinical trial is to evaluate weight loss with TORe and intensive lifestyle modification versus intensive lifestyle modification alone in subjects who have regained weight following a Roux-en-Y gastric bypass.\n\nParticipants will randomized 2:1. Those randomized to the TORe arm will receive a TORe procedure and intensive lifestyle modification which consists of a well-balanced calorie restrictive diet, incorporation of exercise and coaching on lifestyle discussion. Participants randomized the lifestyle modification alone arm will be eligible to receive a TORe procedure at 6 months post enrollment. Total follow up will be 24 months.",[29,64],"Weight Loss",[66,67],"TORe","OverStitch","2026-06-11",{"date":70,"type":42},"2026-06-12",{"date":72,"type":42},"2026-04-14",{"date":74,"type":21},"2028-11",{"name":76,"class":77},"Boston Scientific Corporation","INDUSTRY",9,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":101},"100639615","testing-a-tailored-approach-to-long-term-weight-loss-success-100639615","NCT07577765","Testing a Tailored Approach to Long-Term Weight Loss Success","Pilot Testing an Adaptive Intervention for Weight Loss Maintenance","Inclusion Criteria:\n\n* BMI of ≥ 27 prior to weight loss\n* Lost ≥ 7% of body mass in the past 6 months\n* Weight loss was intentional\n* No plans for weight loss surgery in the next 6 months\n* Access to a smart device that can download applications and receive text messages\n* Able to receive clearance for study participation from primary care provider\n\nExclusion Criteria:\n\n* Pregnant or within 12 months postpartum, or planning pregnancy\n* Uncontrolled conditions that affect overall health (cardiovascular, metabolic, renal, pulmonary, psychiatric, thyroid, cancers)\n* Food insecure\n* Bariatric surgery or cancer treatment within the past 5 years\n* Active or recent (\\\u003C12 months) treatment\u002Fdiagnosis of an eating disorder",true,{"count":88,"type":21},30,[24],"The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are:\n\n* Is an adaptive intervention with tailored re-engagement support feasible for individuals following intentional weight loss?\n* Does this intervention prevent weight regain after intentional weight loss?\n\nParticipants will:\n\n* Complete a baseline assessment of body measurements\n* Complete surveys on dietary intake, mental health, and physical activity\n\nParticipants will also engage in a 26-week program, which involves:\n\n* Receive regular educational texts\u002Femails\n* Fill out weekly online survey check-ins\n* Weigh themselves at least weekly on a scale provided by the study\n* Some participants may receive health coaching during portions of the study.\n* Assessments will be repeated for all participants at the end of the intervention period.",[64,29,27],"2026-05-04",{"date":94,"type":42},"2026-05-11",{"date":96,"type":42},"2026-01-07",{"date":98,"type":21},"2027-09-01",{"name":100,"class":49},"University of Utah",1,{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":50},"100411610","monitoring-the-weight-evolution-using-a-connected-scale-100411610","NCT04639778","Monitoring the Weight Evolution Using a Connected Scale","Evaluation of a Personalized Care Path After Bariatric Surgery Based on Monitoring the Weight Evolution Using a Connected Scale","TELEBARIA","Inclusion Criteria:\n\nPatients aged\\> = at 18 years old Patients who have benefited from a Roux-en-Y Gastric By-Pass or Sleeve Gastrectomy bariatric surgery 2 years ago Preoperative Body Mass Index between 35 kg\u002Fm2 and 59 kg\u002Fm2 Access to the wired network at home. Social insured patient Patient who signed the informed consent\n\nExclusion Criteria:\n\nLack of autonomy for the use of remote monitoring equipment or psychological or psychiatric disorders making it difficult to optimally use the remote monitoring equipment\n\nAdministrative reasons: inability to receive informed consent information, inability to participate in the entire study, lack of social security coverage, refusal to sign consent, patient under guardianship or justice system.",{"count":111,"type":21},390,[24],"Current guideline recommend yearly multidisciplinary postoperative follow-up after bariatric surgery. However, practices remain very heterogeneous, and only a fraction of patients are still follow-up beyond two years after the operation.\n\nThis study will assess a new care pathway in which the patients are follow-up according to the weight evolution measured by the patient using a connected scale.",[28,115,29],"Long Term Follow-Up","2025-12-17",{"date":118,"type":42},"2025-12-24",{"date":120,"type":42},"2021-03-25",{"date":122,"type":21},"2026-12",{"name":124,"class":49},"University Hospital, Lille",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":132,"maxAge":18,"enrollmentInfo":133,"targetDuration":4,"studyType":135,"phases":4,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":101},"100577684","the-application-of-gastric-bypass-stents-in-patients-with-weight-regain-after-laparoscopic-sleeve-gastrectomya-feasibility-study-100577684","NCT06801496","The Application of Gastric Bypass Stents in Patients with Weight Regain After Laparoscopic Sleeve Gastrectomy：a Feasibility Study","DJBL for LSG","Inclusion Criteria:\n\n* 1、For those with simple obesity, BMI ≥ 32.5, or 27.5 ≤ BMI \\\u003C 32.5, who have difficulty controlling their condition with lifestyle modifications and medical treatment, and who meet at least two criteria for metabolic syndrome components, or have comorbidities.\n\n  2、For those with simple obesity, 27.5 ≤ BMI \\\u003C 32.5, and with male waist circumference ≥ 90 cm, female waist circumference ≥ 85 cm, and imaging studies suggesting central obesity.\n\n  3、For those with type 2 diabetes, BMI ≥ 27.5, who still have some residual insulin secretion capacity.\n\nExclusion Criteria:\n\n* 1、Non-obese type 1 diabetes; 2、Those for whom the purpose of treatment is T2DM, but whose pancreatic beta-cell function is largely lost, with a BMI \\\u003C 25.0; 3、Age \\\u003C 16 years or age \\> 65 years; 4、Pregnant women with diabetes and patients with certain special types of diabetes; 5、Those with a cognitive disorder or immature intelligence, and who cannot control their behavior; 6、Those whose expectations for the surgery are not realistic; 7、Those unwilling to assume the risks of potential surgical complications; 8、Those unable to comply with postoperative dietary and lifestyle changes, showing poor compliance; 9、Those in poor general health, who are unable to tolerate general anesthesia or surgery.","16 Years",{"count":134,"type":21},100,"OBSERVATIONAL","This study is based on the National Center for Integrated Traditional Chinese and Western Medicine, utilizing the centralized advantages of our department and integrating multiple disciplines (general surgery, endocrinology, nutrition, sports, and traditional Chinese medicine). It focuses on the effectiveness of gastric bypass stents in treating patients with postoperative obesity after laparoscopic sleeve gastrectomy, as well as in patients with simple obesity. This will improve the prognosis of patients and reduce the medical burden.",[138,29],"Obesity and Obesity-related Medical Conditions","2025-01-25",{"date":141,"type":42},"2025-01-30",{"date":143,"type":42},"2023-08-01",{"date":145,"type":21},"2025-12-31",{"name":147,"class":49},"China-Japan Friendship Hospital"]