[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"well-being\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:well-being":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,23,0,[8,51,89,121,152,179,211,224,253,279,308,350,380,408,434,469,503,541,576,618,644,668,688],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100053402","technology-assisted-methods-to-advance-suicide-prevention-among-youth-in-colombia-100053402",false,"NCT06651554","Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia","Harnessing Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombian School Settings","Inclusion Criteria for youth:\n\n* aged 14-19\n* attending a secondary school in Bogota\n* willing to try the digital platform\n\nExclusion Criteria for youth:\n\n* not meeting inclusion criteria",true,"ALL","14 Years","19 Years",{"count":21,"type":22},228,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will investigate a multi-level approach that applies technology-assisted methods to reduce suicidal thoughts and behaviors (SIB) and promote mental health among Colombian youth: (a) digital platform for youth; (b) digital platform for teachers; and (c) hybrid mental health training diploma program for teachers. This approach will evaluate an open-access digital platform for suicide prevention among Colombian youth. Key features of the digital platform include mental health self-help tools, a customizable safety plan, links to online counseling services, and gamification elements. The digital platform's teacher interface will incorporate psychoeducation, brief suicide-risk screening and decision support tools to enhance teacher capacity to assess risk for suicide and refer youth to the appropriate level of services.\n\nStudy investigators will conduct a hybrid-type 1 implementation-effectiveness stepped wedge pilot trial design to evaluate the digital platform and hybrid mental health teacher training program implemented within secondary schools in Bogota, Colombia. Study aims are to:\n\nAim 1. An initial needs assessment will be conducted with key stakeholders (youth, teachers, caregivers, school administrators) to identify barriers and facilitators to successful implementation of the multi-level approach. User-centered design methods will be used to refine the digital platform and incorporate end-user feedback into the final prototype.\n\nAim 2. Investigators will evaluate: (a) feasibility, acceptability, and usability of the digital platform across three schools in Colombia; and (b) the preliminary effects of the digital platform in reducing SIB and improving mood (e.g., anxiety\u002Fdepression) among Colombian youth aged 14-19 attending the three schools. Safety planning skills acquisition (youth-level) and linkages to mental health services (service-level) will be assessed as potential mechanisms of change.\n\nAim 3. The study will apply a multi-disciplinary capacity building model to strengthen behavioral health and implementation science research, healthcare delivery capacity, and mental health policy. In partnership with Pontificia Javeriana University, experts in suicide prevention, data science, and implementation science will be engaged to build in-country research capacity at the individual and institutional level.",[28,29,30,31],"Suicidal Ideations","Suicidal Behaviors","Depression, Anxiety","Well-being",[33,34,35,36,37],"suicide prevention","adolescent health","mHealth","Colombia","Implementation Science","RECRUITING","2026-07-10",{"date":41,"type":42},"2026-07-13","ACTUAL",{"date":44,"type":42},"2025-05-12",{"date":46,"type":22},"2027-01-31",{"name":48,"class":49},"Brown University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":16,"sex":17,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":50},"100643822","phase-1-psilocybin-efficacy-with-or-without-pimavanserin-pretreatment-100643822","NCT07610135","Psilocybin Efficacy With or Without Pimavanserin Pretreatment","PRISMatic: A Phase 1b Randomized, Double-Armed, Parallel-Group, Placebo-Controlled Trial of Psilocybin Efficacy With or Without Pimavanserin Pretreatment","PRISMatic","Inclusion Criteria:\n\n* Adults aged 21 to 65 years old\n* Fluency in English\n* At least high school level of education\n* Right-handed\n* Female participants of childbearing potential must agree to use a highly effective method of contraception throughout the study. Highly effective methods are defined as those that, when used consistently and correctly (alone or in combination), are associated with a failure rate of less than 1% per year. Condoms alone are not considered highly effective. Abstinence is not considered a highly effective method. However, at the investigator's discretion, abstinence may be accepted if, based on the investigator's judgment and knowledge of the participant's usual and preferred lifestyle, it can be reasonably expected to result in 100% effectiveness.\n* Agree to abstain from any psychoactive drugs on the day prior to and the day of the drug administration session as demonstrated by a negative toxicology report.\n* Agree to consume approximately the same amount of caffeine-containing beverage (e.g., coffee, tea) that he\u002Fshe consumes on a usual morning, before arriving at the research unit on the mornings of drug session days. If the participant does not routinely consume caffeinated beverages, he\u002Fshe must agree not to do so on session days.\n* Agree not to take any PRN medications on the mornings of drug sessions\n* Agree that for one week before the drug session, he\u002Fshe will refrain from taking any nonprescription medication, nutritional or herbal supplement except when approved by the study investigators. Exceptions will be evaluated by the study investigators and will include acetaminophen, non-steroidal anti-inflammatory drugs, and common doses of vitamins and minerals.\n\nExclusion Criteria:\n\n* Non-English speakers and those with language or hearing impairments\n* Left-handedness (assessed by the Edinburgh Handedness Inventory)\n* Any lifetime history of psychedelic use, including serotonergic compounds (e.g., psilocybin, LSD, mescaline, DMT, 5-MeO-DMT) and nontraditional psychedelics (e.g., MDMA, ketamine, ibogaine)\n* Presence of cardiac, pulmonary, vascular, renal, hepatic, or other significant medical comorbidities\n* Cardiovascular conditions: coronary artery disease, stroke, angina, uncontrolled hypertension (systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, and HR \\>90 bpm), a clinically significant ECG abnormality (e.g., atrial fibrillation), prolonged QTc interval (i.e., QTc \\> 450 msec), heart valve, or TIA in the past year\n* QTc interval prolongation exclusionary criteria: medications known to prolong the QT interval (including: Class 1A antiarrhythmics (e.g., quinidine, procainamide), Class 3 antiarrhythmics (e.g., amiodarone, sotalol), certain antipsychotics (e.g., ziprasidone, chlorpromazine, thioridazine), certain antibiotics (e.g., gatifloxacin, moxifloxacin), subjects with congenital prolongation of the QT interval; subjects with family history positive for long QT syndrome; subjects with a history of cardiac arrhythmias; and subjects with history of any cardiovascular disorder\u002Fcondition known to increase the possibility of QT prolongation and torsades de pointes (i.e., symptomatic bradycardia, hypokalemia, hypomagnesemia, hypocalcemia, heart failure, or Brugada Syndrome).\n* Lifetime history of serious psychiatric or neurological disorders, including bipolar disorder, psychosis, or seizure disorder\n* Lifetime history of severe substance use disorder\n* Current (within past six months) substance use disorder of moderate or greater severity\n* Clinically significant suicidal ideation (with strong intent or means) within the past 6 months or lifetime history of suicide attempt, current suicidal ideation, or otherwise judged by a study clinician to be more than low risk for suicidality\n* Current use\u002Fpositive toxicology for illicit drugs at screening and prior to drug administration session (includes illicit, non-prescribed, or prohibited substances such as amphetamines, barbiturates, buprenorphine, benzodiazepines, cocaine, MDMA, methadone, opioids, phencyclidine (PCP), and tetrahydrocannabinol (THC))\n* Nicotine user consuming the equivalent of ≥ 10 cigarettes\u002Fday\n* Altered gastrointestinal anatomy \\[history of surgeries that promote a general intestinal malabsorption (e.g., jejunoileal bypass, jejunocolic bypass, roux-en-Y gastric bypass, vertical banded gastroplasty, gastric band, gastric stapling, sleeve gastrectomy, biliopancreatic diversion with partial gastrectomy, distal gastric bypass, duodenal switch)\\]\n* Weight \\\u003C 40kg\n* Have a first degree relative with schizophrenia or other psychotic disorders (except substance\u002Fmedication-induced or due to another medical condition), or bipolar I disorder\n* MRI contraindications (e.g., claustrophobia incompatible with MRI scanning, medical device or implant incompatible with MRI, prior history as a metal worker and\u002For certain metallic objects in the body). Must complete MRI screening form and be approved by MRI technologist before each scan.\n* Unable or unwilling to perform study procedures, or inappropriate for further study participation as determined by the PI and\u002For study clinicians","21 Years","65 Years",{"count":62,"type":22},20,[64,65],"PHASE1","PHASE2","Twenty healthy adults (≥21 years old) will be enrolled to evaluate the efficacy of a single oral dose of psilocybin (25 mg) administered with or without pretreatment using oral pimavanserin (34 mg) or placebo. Outcome assessments will occur at 1 week and 1 month following psilocybin administration.\n\nThe purpose of this study is to clarify the receptor-level mechanisms underlying psilocybin's effects on mood and well-being, along with the associated neurophysiologic signatures. These mechanisms will be examined using psychometric scales, autonomic and fMRI-based neurophysiologic markers, and integrated pharmacokinetic\u002Fpharmacodynamic modeling.",[68,69,70,71],"Mood (Psychological Function)","Well Being","Mood","Healthy",[73,74,75,76,77,78],"Psilocybin","Randomized Controlled Trial","Tryptamine","Pimavanserin","Indoles","Indole Alkaloid","NOT_YET_RECRUITING","2026-06-04",{"date":82,"type":42},"2026-06-08",{"date":84,"type":22},"2026-07",{"date":86,"type":22},"2028-12",{"name":88,"class":49},"Johns Hopkins University",{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":4,"studyType":23,"phases":100,"briefSummary":101,"conditions":102,"keywords":105,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":120},"100638866","effects-of-binaural-beats-and-spatialized-music-on-behavioural-and-psychological-symptoms-of-dementia-in-assisted-living-facility-residents-100638866","NCT07626944","Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents","Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents: A Randomized Controlled Pilot Protocol","Inclusion Criteria:\n\n* (1) age 55-95 years; (2) the subject and\u002For his\u002Fher legal guardian have signed written informed consent; (3) the subject is able to complete the entire trial period; and (4) a minimum of fifty percent of the subjects will have a diagnosis of a dementia condition with a moderate to severe progression.\n\nExclusion Criteria:\n\n* (1) profound hearing loss or impairment; (2) history of seizures, epilepsy (especially sound-induced epilepsy), claustrophobia, or other conditions that put the subject at risk during the trial; (3) physical or mental conditions that may result in inability to complete and\u002For affect the efficacy of assessment.","55 Years","95 Years",{"count":99,"type":22},120,[25],"The purpose of this study is to investigate the effects of Binaural Beat Music (BBM; personalized music playlist with binaural beats), Spatialized Music (SM; personalized and spatialized music playlist), their combination, and possible interaction on older adults in an assisted living community who are either living with a dementia diagnosis or are experiencing typical age-related changes. The control condition is a personalized music playlist without binaural beats and spatialization. It is hypothesized that BBM, SM, and their combination each improve aspects of BPSD compared to controls over a two-week intervention period.\n\nThe Specific Aims of the study are (1) to evaluate whether BBM, SM, and\u002For their combination is superior to control in reducing BPSD severity (primary outcome); (2) to evaluate whether BBM, SM, and\u002For their combination is superior to control in reducing caregiver distress (secondary outcomes); and (3) to evaluate the effects of BBM, SM, and\u002For their combination on improving overall well-being and mood (secondary outcomes).",[103,104,31,70],"BPSD","Caregiver Distress",[106,31,70,104,107,108,109,110,74,111],"Dementia","Personalized Music Listening","Binaural Beat Stimulation","Spatial Audio","Artificial Intelligence","Assisted Living Residences","2026-05-29",{"date":80,"type":42},{"date":115,"type":42},"2026-05-04",{"date":117,"type":22},"2026-06-27",{"name":119,"class":49},"Maharishi International University",2,{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":23,"phases":132,"briefSummary":133,"conditions":134,"keywords":138,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":120},"100610493","supporting-families-in-the-icu-100610493","NCT07228299","Supporting Families in the ICU","Supporting Families in the ICU: The Chaplain Family Project Multicenter RCT","SF-ICU","We will enroll patient\u002Fsurrogate dyads.\n\nPatients will be eligible if:\n\n* They are age 18 or older at the time of screening.\n* They are judged to lack decisional capacity based on either:\n\na Glasgow Coma Scale (GCS) score of 8 or less; or a GCS of 9-13 with at least one secondary criterion (intubation, sedation, delirium, or noted by clinicians to be unresponsive, comatose or unable to follow commands).\n\n\\* They have an eligible surrogate willing to participate.\n\nSurrogates will be eligible if:\n\n* They are age 18 or older,\n* They are considered the legally authorized representative (LAR) based on prior appointment by the patient or each state's medical consent law.\n\nPatient\u002Fsurrogate dyads will be ineligible if:\n\n\\* They are unable to complete enrollment activities within 96 hours of admission to the ICU.\n\nPatients will be ineligible if:\n\n* They are being discharged from the ICU within 24 hours.\n* They are intubated for surgery but expected to be extubated soon (typically within 24 hours).\n* They are imminently dying or have a planned terminal wean.\n\nSurrogates will be ineligible if:\n\n\\*They are unable to complete study procedures in English.","18 Years",{"count":131,"type":22},64,[25],"The overarching goal of our work is to test the effect of high-quality spiritual care for ICU family surrogates on outcomes of psychological and spiritual well-being and medical decision making. Our team has developed an approach to high quality spiritual care intervention for ICU surrogates, called the Spiritual Care Assessment and Intervention (SCAI) framework, which is delivered by a chaplain interventionist to ICU surrogates.",[135,136,137],"Anxiety","Well-Being","Satisfaction",[139,140,141,142,143],"spirituality","religion","surrogate decision making","proxy decision making","chaplain",{"date":145,"type":42},"2026-05-06",{"date":147,"type":22},"2026-06-01",{"date":149,"type":22},"2026-08-31",{"name":151,"class":49},"Indiana University",{"id":153,"slug":154,"hasResults":11,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":4,"eligibilityCriteria":158,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":159,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":162,"conditions":163,"keywords":164,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":50},"100514046","evaluation-of-a-personalised-digital-intervention-evibody-for-healthy-and-sustained-lifestyle-behaviors-and-well-being-among-adults-a-real-world-quasi-experimental-study-100514046","NCT05973383","Evaluation of a Personalised Digital Intervention (EviBody) for Healthy and Sustained Lifestyle Behaviors and Well-being Among Adults: a Real-world Quasi-experimental Study","Effectiveness and Theory-based Evaluation of a Personalised Digital Intervention (EviBody) for Healthy and Sustained Lifestyle Behaviours and Well-being Among Adults","Inclusion Criteria (intervention arms):\n\n* adults ≥18 years\n* signing up for the app EviBody using electronic identification\n* consent to the research study\n\nInclusion Criteria (controls):\n\n* adults ≥18 years\n* consent to the research study\n\nExclusion Criteria (intervention arms):\n\n* individuals who are discharged from the app due to refracting the terms of the service,\n* is currently using a digital product that is explicitly designed to support behaviour change,\n* subjects scoring \\>70 on well-being will be excluded from the primary analyses,\n* subjects who appear as friends, colleagues, or family with anyone in the research or owner group will be excluded.\n\nExclusion Criteria (controls):\n\n* is currently using a digital product that is explicitly designed to support behaviour change,\n* is found to be a user of EviBody,\n* subjects scoring \\>70 on well-being will be excluded from the primary analyses,\n* subjects who appear as friends, colleagues, or family with anyone in the research or owner group will be excluded.",{"count":160,"type":22},1500,"OBSERVATIONAL","The goal of this quasi-experimental observational study is to evaluate the impact of a personally tailored digital intervention aimed to support a healthy lifestyle on well-being, lifestyle behaviors, and mental health among the adult population.\n\nThe main questions it aims to answer are:\n\nI) Is a digital intervention developed to offer personalised digital support for healthy habits effective in improving well-being compared to a control group from the general population after 6 months? II) Is the effectiveness dose-dependent (better effect with higher membership level)? III) Does the digital intervention assist in maintaining healthy eating and physical activity habits, mental health, and well-being across 24 months? IV) Are sociodemographic factors associated with achieving the self-identified goals and improvements in eating and physical activity habits, mental health, and well-being? VI) Do engagement, motivation, self-efficacy, and perceived barriers mediate the associations between sociodemographic characteristics and changes in self-identified goals, eating and physical activity habits, mental health, and well-being over a 24-month period? V) How is the pattern of user engagement across 24 months?\n\nParticipants are users of the mobile phone application EviBody. The group will be compared with individuals from the general population to evaluate if the digital intervention is effective in improving well-being, eating and physical activity habits, and mental health.",[31],[165,166,167,168,169],"primary prevention","secondary prevention","health promotion","self-management","behavior","2026-04-23",{"date":172,"type":42},"2026-04-29",{"date":174,"type":42},"2026-01-01",{"date":176,"type":22},"2028-12-31",{"name":178,"class":49},"Sophiahemmet University",{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":186,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":188,"conditions":189,"keywords":198,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":209,"locationsCount":4},"100632068","elderly-care-in-transition---perspectives-of-the-elderly-and-the-staff-100632068","NCT07508878","Elderly Care in Transition - Perspectives of the Elderly and the Staff","Elderly Care in Transition - The Elderlys' and the Staffs' Perspective on Person-centered Care, Environment, Health and Well-being","Inclusion Criteria - Older people:\n\n* Living in nursing homes - academic or standard\n* Able to complete a questionnaire independently or with reading assistance\n\nInclusion Criteria - Staff:\n\n* Employed at an Academic nursing home or a regular nursing home (comparison unit)\n* Belonging to care, nursing, or rehabilitation staff, including registered nurses, occupational therapists, and physiotherapists\n* Able to complete a questionnaire\n\nExclusion Criteria - Older people:\n\n* Individuals receiving only safety alarm services and\u002For meal delivery (no ongoing care contact)\n* Individuals unable to provide informed consent\n* Individuals unable to complete a questionnaire, even with reading assistance\n* Individuals with acute medical conditions that make participation inappropriate (as judged by care staff)\n* Individuals with severe cognitive impairment preventing meaningful participation in surveys.",{"count":187,"type":22},600,"Elderly care in Sweden faces several significant challenges. The number of older people is increasing at the same time as there are fewer of working age. Elderly care staff, such as nurses, care assistants and nurses, have on average more sick days than many other professional groups and often experience high work-related stress. In some municipalities, there are also problems with high staff turnover and a lack of formal competence. At the same time, research shows that many employees experience work in elderly care as meaningful and valuable. Taking advantage of and strengthening these positive aspects is central to creating good conditions for the health and well-being of staff and for the quality of care and care for older people. An important area of development in elderly care is person-centred care, which means that care is based on the individual person's needs, wishes, life history and resources. Person-centred practice emphasises the relationship between the older person, the staff and, if the person so wishes, relatives. Although person-centered care is often seen as an obvious part of good care, research shows that it is not fully implemented in practice and that the introduction of person-centered working methods can be complex and demanding.\n\nThis study is being carried out in collaboration between municipalities and the University of Gävle and is linked to the establishment of nursing homes for the elderly that will function as academic nursing homes. In these nursing homes, person-centered care will be a pronounced focus area. Through recurring measurements, the activities will be monitored and developed in close collaboration between practice and research. The overall aim of the study is to investigate older people's experience of academic nursing homes with a focus on person-centered care and nursing, outdoor environment, health and well-being, and to investigate the staff's experience of person-centered working methods, learning, structural conditions and work-related well-being. The study also aims to analyze the relationship between older people's experiences of person-centered care, outdoor environment, health and well-being, both among older people living in academic nursing homes and among older people living in their own homes. The study has a longitudinal design and data will be collected at several points in time using questionnaires and interviews, which enables both statistical analyses and an in-depth understanding of the participants' experiences over time. By highlighting the perspectives of both older people and staff, the study can contribute new knowledge about how person-centered care can be developed and maintained in practice. In the long term, the results can contribute to a more health-promoting, sustainable and attractive elderly care for both older people and staff.",[190,69,191,192,193,194,195,196,197],"Person-Centred Care","Health","Environment","Work-related Well-being","Structural Conditions","Learning Development","Older People","Staff Working in Nursing Homes",[199,200,201,202],"person-centered care","elderly care","work-related well-being","health","2026-03-30",{"date":205,"type":42},"2026-04-02",{"date":207,"type":22},"2026-04-01",{"date":176,"type":22},{"name":210,"class":49},"University of Gavle",{"id":212,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":213,"targetDuration":4,"studyType":23,"phases":214,"briefSummary":26,"conditions":215,"keywords":216,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":221,"leadSponsor":223,"locationsCount":50},"100566159",{"count":21,"type":22},[25],[28,29,30,31],[33,34,35,36,37],"2026-03-19",{"date":219,"type":42},"2026-03-23",{"date":44,"type":42},{"date":222,"type":22},"2028-05-31",{"name":48,"class":49},{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":230,"eligibilityCriteria":231,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":234,"conditions":235,"keywords":236,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":247,"completionDateStruct":249,"leadSponsor":251,"locationsCount":50},"100626110","validation-of-the-shared-happiness-index-in-multidisciplinary-primary-care-practices--be-api--100626110","NCT07431372","Validation of the Shared Happiness Index in Multidisciplinary Primary Care Practices ( Be aPi )","Validation of the Shared Happiness Index in Multidisciplinary Primary Care Practices","Be aPi","Inclusion Criteria:\n\n* Healthcare professionals (medical, paramedical) and professionals in the medical-social sector, medical assistants, health coordinators and mediators, as well as adapted physical activity instructors and psychologists\n* who work in healthcare centres that had been operating for more than one year at the start of the study and who themselves had more than one year's seniority in the MSP.\n\nExclusion Criteria:\n\n* Substitute professionals,\n* Secretaries without coordination or medical assistant duties Professionals belonging to MSPs that had been operating for less than one year at the start of the study and who had less than one year's seniority within the organisation.",{"count":233,"type":22},350,"Multi-professional primary care practices (Maisons de Santé Pluriprofessionnelles, MSP) have expanded widely in France over the last decade to respond to increasing healthcare needs, uneven distribution of physicians, and deteriorating working conditions, which were further exacerbated by the COVID-19 pandemic. MSPs are expected to offer more collaborative and coordinated care, and to provide a more attractive work environment, particularly for younger healthcare professionals seeking less isolation and better work-life balance.\n\nWell-being at work for healthcare professionals is now recognised as a key determinant of quality and safety of care. Studies have shown links between staff satisfaction, burnout, and patient outcomes, including communication quality, error rates and staff retention. However, research specifically focused on collective well-being or \"shared happiness\" within multi-professional primary care teams remains limited. Existing work in French MSPs (notably qualitative studies by F. Burté and O. Caillaud) has identified relevant dimensions of \"shared happiness\" and led to the preliminary construction of a questionnaire named the Shared Happiness Index (Indice de Bonheur Partagé, IBP). To date, no validated, standardised instrument exists to measure this collective well-being in MSPs.\n\nThe Be\\_aPi study aims to validate the IBP questionnaire among healthcare professionals working in MSPs. The study is observational, descriptive and cross-sectional, conducted in several French regions covered by the GIRCI (Groupement Interrégional de Recherche Clinique et Innovation) SOHO (Sud-Ouest Outre-Mer Hospitalier) network (Nouvelle-Aquitaine, Occitanie, Réunion and Mayotte). It comprises three main steps. First, a content validation phase will be carried out with two independent panels of experts. One panel, including psychometrics, methodology and linguistics experts and MSP representatives, will assess face validity by examining each item in relation to the concept of shared happiness in multi-professional primary care. A second panel will be involved in an e-Delphi process to establish consensus validity on the relevance and clarity of items, using Likert-type ratings and iterative feedback.\n\nSecond, the psychometric validation phase will recruit approximately 350 professionals from over 100 MSPs. Eligible participants include medical and paramedical professionals, medical-social staff, medical assistants, coordinators, health mediators, adapted physical activity instructors and psychologists, working in MSPs that have been operating for at least one year, with at least one year of seniority in their current MSP. Participants will complete an online survey including the IBP questionnaire and three reference instruments: the Maslach Burnout Inventory (MBI), the General Health Questionnaire-12 (GHQ-12) and the Short Form-12 (SF-12). Internal consistency of the IBP will be assessed using Cronbach's alpha, and construct validity will be examined with exploratory factor analysis and correlation patterns with the reference scales, according to a multi-trait multi-method approach.\n\nThird, to evaluate test-retest reliability, participants who completed the initial IBP will be invited to fill in the same questionnaire again after a delay of approximately one month. The stability of scores over time will be assessed using intraclass correlation coefficients. Ceiling and floor effects, as well as the distribution of scores across professional categories and organisational characteristics of MSPs (e.g. single-site vs multi-site, role in the organisation, membership in interprofessional associations), will also be analysed.\n\nThe expected outcome of Be\\_aPi is a valid, reliable and transferable Shared Happiness Index specifically tailored to multi-professional primary care practices. This tool should enable regular monitoring of collective well-being, support targeted quality-of-work-life interventions, and ultimately contribute to improving quality and safety of care, staff retention and the long-term sustainability of MSPs. In the longer term, the IBP could inform policy instruments and financing schemes that aim to \"take care of those who care,\" in line with national quality and safety strategies.",[69],[237,238,239,240,241,242,243],"shared hapiness","Primary care","Multidisciplinary primary care practices","Work-related well-being","Quality of work life","Burnout","Shared happiness","2026-02-23",{"date":246,"type":42},"2026-02-24",{"date":248,"type":22},"2026-03",{"date":250,"type":22},"2027-09",{"name":252,"class":49},"Centre Hospitalier Universitaire de la Réunion",{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":259,"eligibilityCriteria":260,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":261,"targetDuration":4,"studyType":23,"phases":263,"briefSummary":264,"conditions":265,"keywords":269,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":271,"lastUpdatePostDateStruct":272,"startDateStruct":274,"completionDateStruct":275,"leadSponsor":277,"locationsCount":4},"100614475","yoga-meditation-and-mindful-eating-intervention-in-university-students-100614475","NCT07280078","Yoga, Meditation and Mindful Eating Intervention in University Students","Evaluation of a Yoga, Meditation and Mindful Eating Intervention for the Control of Stress, Anxiety, Depression, and Mindfulness in University Students","Yoga-UDEA","Inclusion Criteria:\n\n* Undergraduate students enrolled in the curso \"Yoga, Meditation, and Mindful Eating\" at the Faculty of Pharmaceutical and Food Sciences (CIFAL), University of Antioquia.\n* Willing to participate voluntarily and complete all study assessments.\n* Able to attend the full program (32 hours over one academic semester).\n\nExclusion Criteria:\n\n* Students currently practicing yoga or meditation regularly.\n* Pregnant women or participants with any medical condition that prevents safe participation in yoga practice.\n* Individuals with severe psychiatric disorders requiring pharmacological treatment.",{"count":262,"type":22},60,[25],"The aim of this study is to learn whether a program that combines yoga, meditation, and mindful eating can help reduce stress, anxiety, and depression, and improve mindfulness in university students.\n\nThe main questions the study aims to answer are:\n\n* Does participating in yoga, meditation, and mindful eating sessions lower students' levels of stress, anxiety, and depression?\n* Does the program improve students' mindfulness and general well-being?\n\nWhat will happen in the study:\n\nParticipants will:\n\n* Attend weekly sessions of yoga, meditation, and mindful eating for 32 hours total.\n* Practice physical postures (Asanas), breathing exercises (Pranayama), relaxation, and meditation.\n* Receive short lessons about mindful nutrition and healthy lifestyle habits.\n* Complete questionnaires before and after the program to measure stress, anxiety, depression, and mindfulness.",[266,135,267,268,31],"Stress, Psychological","Depression","Mindfulness",[270],"Yoga, Meditation, Stress, Psychological; Anxiety; Well-being; Mindful Eating; Psychological","2026-02-16",{"date":273,"type":42},"2026-02-18",{"date":84,"type":22},{"date":276,"type":22},"2026-08",{"name":278,"class":49},"Universidad de Antioquia",{"id":280,"slug":281,"hasResults":11,"nctId":282,"briefTitle":283,"officialTitle":283,"acronym":284,"eligibilityCriteria":285,"healthyVolunteers":11,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":286,"targetDuration":4,"studyType":23,"phases":288,"briefSummary":289,"conditions":290,"keywords":295,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":50},"100621487","effects-of-virtual-reality-with-multisensory-stimulation-on-emotional-and-behavioral-disorders-in-individuals-with-acquired-brain-injury-and-disability-requiring-institutional-care-a-single-case-experimental-design-sced-study-100621487","NCT07371260","Effects of Virtual Reality With Multisensory Stimulation on Emotional and Behavioral Disorders in Individuals With Acquired Brain Injury and Disability Requiring Institutional Care: a Single Case Experimental Design (SCED) Study.","Rév In MAS","Inclusion Criteria:\n\n* Resident aged over 18\n* Diagnosis of stroke, traumatic brain injury, tumor, or cerebral anoxia for more than 3 years.\n* Living in a nursing home for at least 6 months\n* Presence of one or more emotional and behavioral disorders during initial assessments (NPI-ES) for at least 3 months.\n* Sufficient cognitive abilities to understand instructions and answer questions using a Likert scale.\n* Normal or corrected visual acuity\n* Resident affiliated with the social security system\n\nExclusion Criteria:\n\n* Motor or sensory disorders incompatible with the use of VR\n* Unstabilized photosensitive epilepsy or presence of a seizure in the past year\n* Change in the prescription of neuroleptic treatments, antidepressants, benzodiazepines, sedatives, anxiolytics, mood stabilizers, antiepileptics, or betablockers within the last 3 months.\n* Unstabilized major psychiatric disorders.\n* Craniectomy\n* Limited range of cervical movement due to orthopedic disorders\n* Moderate or severe hearing loss not compensated by a hearing aid\n* Anosmia\n* Asthma\n* Pregnant women or women suspected of being pregnant\n* Breastfeeding women\n* Neurocognitive disorders preventing understanding of instructions during assessments\n* The resident is included in another research protocol",{"count":287,"type":22},3,[25],"Acquired brain injuries (ABIs) frequently cause emotional and behavioral disorders that impair independence and quality of life, particularly in institutions. Virtual reality (VR), already used in various mental and neurological disorders, offers therapeutic potential that remains largely unexplored in this context.\n\nMultisensory devices offer enhanced immersion that can potentially increase the relaxation and calming effect. Their use in specialized care home (SCH) could provide additional support for care.\n\nThe main objective of the study is to measure the effect of an 8-week multisensory VR relaxation program on the most significant emotional and behavioral disorders in adults with acquired brain injury living in SCH. The SCED method with multiple baselines across subjects (ABA) is used with three adult residents with ABCI and behavioral disorders living in SCH. The study consists of three phases (baseline, intervention, follow-up), during which the three main emotional and behavioral disorders of each resident are assessed weekly based on observations made throughout the week. Additional measures include the assessment of the socio-emotional profile by the care team (ECCSEG) and the emotional distress experienced by residents (QOLIBRI), collected twice per phase. The intervention consists of eight weeks of VR relaxation (VirtySens®), with two 15-minute sessions per week.\n\nAll measurements taken during the experiment will be anonymized and used only by the investigators, who are fully aware of the European GDPR (General Data Protection Regulation) concerning the protection of personal data.",[291,292,293,294,31],"Brain Injury","Virtual Reality","Behavior","Emotion",[296,293,294,31,292,297,298],"Acquired Brain Injury","Multisensory","Specialized Care Home","2026-01-19",{"date":301,"type":42},"2026-01-27",{"date":303,"type":22},"2026-02-15",{"date":305,"type":22},"2027-02-01",{"name":307,"class":49},"Hopital La Musse",{"id":309,"slug":310,"hasResults":11,"nctId":311,"briefTitle":312,"officialTitle":312,"acronym":313,"eligibilityCriteria":314,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":315,"targetDuration":4,"studyType":23,"phases":317,"briefSummary":318,"conditions":319,"keywords":329,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":341,"lastUpdatePostDateStruct":342,"startDateStruct":344,"completionDateStruct":346,"leadSponsor":348,"locationsCount":120},"100611237","cocreating-action-to-improve-rationality-in-the-health-system-100611237","NCT07237971","Cocreating Action to Improve Rationality in the Health System","CAIR","Survey general population:\n\nA representative population survey of adult (aged 18 years and over) who are residents in the Municipal District 2 of Elche (Spain).\n\nSurvey community pharmacies:\n\nIndividuals who visit the pharmacies collaborating in the Municipal District 2 of Elche (Spain) to obtain any of the medications, aged 18 years and over for three a priori established medication groups.\n\n* Group 1 (Antidepressants and Anxiolytics): N05B, N05C, N06A.\n* Group 2 (Cardiovascular disease risk factor medication): A10B (antidiabetics), C10A (cholesterol-lowering drugs), C07A, C09A, C03C, C08C (antihypertensives).\n* Group 3 (Antibiotics): J01\n\nHealth service data from primary care:\n\nA series of aggregate indicators will be collected from the electronic information systems of the regional health authorities (Conselleria de Sanidad de la Generalitat Valenciana), which hosts information on both prescriptions made by physicians and those dispensed in the community pharmacies of the Valencian Community. These indicators will be calculated for individuals aged 18 years and over for groups 2 and 3, and 12 years and over for group 1 using aggregate data from health system's registries and, therefore, not considering 12 years old as minimum age limit of the eligible participants in the present study protocol registry. Furthermore, aggregate data about the number of consultations will be collected in the two primary care facilities in the study area for individuals aged 18 and over.\n\nQualitative methods and cocreation procedure:\n\nFocus groups, sociograms and in-depth interviews will include 6-8 participants and last approximately 90 minutes. Participation in the co-creation process will be open, voluntary, and will depend on the interest of individuals and entities in the area. Eligibility criteria:\n\n* People aged 18 and over who are residents or have a job or family connection in the Municipal District 2 of Elche (Spain) who are interested in participating, wish to be actively involved in the co-creation, planning, and implementation of community initiatives, and are available to attend the conferences, meetings, and workshops.\n* Representatives from community institutions and associations, including professionals from the Elche Public Health Center, primary care teams in the area, Elche Council staff, as well as professionals and volunteers from NGOs and other local organizations with experience in community work in the district.",{"count":316,"type":22},4000,[25],"Despite widespread recognition of social, economic, or environmental health determinants, health action remains heavily dominated by individual-level solutions (e.g., medication, patient counselling, vaccination). This study aims to stimulate changes in health system functioning by demonstrating how the cocreation of actions to address psychological well-being, cardiovascular health, and antimicrobial resistance from within the community can alleviate the burden on primary care services, reduce medicalisation and increase health equity.\n\nThe scientific approach uses mixed methods and incorporates theory from multiple disciplines. This study will appraise how the current system addresses psychological well-being, cardiovascular (CV) health, and rational use of antibiotics using a population survey, a survey of patients collecting their medication at community pharmacies, aggregate health service indicators on medication consumption and primary care consultations, and qualitative methods exploring stakeholders' perceptions.The investigators will undertake community-based participatory research to engage citizen scientists in the cocreation of community-led actions to promote psychological well-being, CV health, and prevent antimicrobial resistance. The design, implementation, and evaluation of the actions will apply an assets-based approach and apply theories and frameworks from implementation science in an iterative manner over 3 years. Finally, the impact of the cocreated actions will be analysed, considering effectiveness and broader contextual issues such as initiative adoption, implementation, and maintenance. The investigators will use a before-after comparison of survey indicators, an interrupted time-series analysis of health service data and qualitative analysis.\n\nThe goal is to demonstrate how the integration of community action with attention to the social determinants of health, can lead to a more rational approach to health care and ultimately improve health and health equity.",[320,321,322,323,324,325,326,327,31,328],"Health-Related Quality-of-Life","Social Capital","Health Literacy","Community Based Participatory Research","Antibiotic Prescription","Mental Health Literacy","Cardio Vascular Disease","Antimicrobial Drug Resistance","Health Equity",[330,331,332,333,334,335,336,337,338,339,340],"Community health","Cocreation action","Health system","Health literacy","Social capital","Community capital","Antibiotic drug use","Cardiovascular drug use","Psychotropic drug use","Health-related quality of life","Health equity","2025-11-24",{"date":343,"type":42},"2025-12-02",{"date":345,"type":42},"2025-10-21",{"date":347,"type":22},"2029-04-01",{"name":349,"class":49},"Universidad Miguel Hernandez de Elche",{"id":351,"slug":352,"hasResults":11,"nctId":353,"briefTitle":354,"officialTitle":355,"acronym":356,"eligibilityCriteria":357,"healthyVolunteers":16,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":358,"targetDuration":4,"studyType":23,"phases":360,"briefSummary":361,"conditions":362,"keywords":367,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":341,"lastUpdatePostDateStruct":373,"startDateStruct":374,"completionDateStruct":376,"leadSponsor":378,"locationsCount":287},"100568905","light-in-healthcare-environment-ljus-i-sjukhusmilj-100568905","NCT06687304","Light in Healthcare Environment (Ljus i sjukhusmiljö)","Benefits of Light in the Radiographic Environment","LIS","Inclusion Criteria:\n\nRadiographer\n\nExclusion Criteria:\n\n\\-",{"count":359,"type":22},18,[25],"The goal of this clinical trial is to learn if light can enhance the feeling of well-being and sleep quality in Radiographers. It will also find out if there is an optimal recipe for light. The main questions it aims to answer are:\n\n* Will alertness, energy levels, and sleep quality increase in radiographers when the lighting is differed?\n* What light recipe is the most beneficial for the personnel? Researchers will compare no enhanced light environment to different enhanced light environment to see if the enhanced light is beneficial for radiographers.\n\nParticipants will:\n\n* Will work in an enhanced light environment or a non-enhanced light environment\n* Answer surveys\n* Take saliva sample",[363,31,364,365,366],"Sleep Quality","Melatonin","Cortisol","Energy Levels",[368,369,370,371,372],"Light","Radiography","Light environment","Circadian rhythm","Personnel at radiology departments",{"date":343,"type":42},{"date":375,"type":42},"2024-11-15",{"date":377,"type":22},"2027-03-31",{"name":379,"class":49},"Lund University",{"id":381,"slug":382,"hasResults":11,"nctId":383,"briefTitle":384,"officialTitle":385,"acronym":4,"eligibilityCriteria":386,"healthyVolunteers":11,"sex":17,"minAge":387,"maxAge":388,"enrollmentInfo":389,"targetDuration":4,"studyType":23,"phases":391,"briefSummary":392,"conditions":393,"keywords":395,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":399,"lastUpdatePostDateStruct":400,"startDateStruct":402,"completionDateStruct":404,"leadSponsor":406,"locationsCount":50},"100588569","nonviolent-communication-for-parents-100588569","NCT06943105","Nonviolent Communication for Parents","Effectiveness of Group-based Nonviolent Communication Interventions for Improving Mental Well-being in Parents: a Randomised Controlled Trial","Inclusion Criteria:\n\n* 1\\) parents aged 24-59 years with children of primary school age;\n* 2\\) with mild to severe depressive symptoms (score \\>5 on the Patient Health Questionnaire (PHQ)-9) (Kroenke et al., 2001) and\u002For mild to severe anxiety symptoms (score \\>5 on the General Anxiety Disorder (GAD)-7) (Spitzer et al., 2006); and\n* 3\\) Hong Kong residents who can understand Cantonese.\n\nExclusion Criteria:\n\n* 1\\) under psychiatric treatment, psychotherapy groups and are classified as unstable cases based on the judgment of the recruiting social workers;\n* 2\\) participating in other related parenting programmes.","24 Years","59 Years",{"count":390,"type":22},172,[25],"This randomised controlled trial (RCT) aims to evaluate the effectiveness of face-to-face Nonviolent Communication (NVC) intervention in improving parents' mental well-being and NVC skills, reducing parenting stress, depression and anxiety symptoms, and child emotional and behavioural problems.\n\nA total of 172 parents with primary-school-age children will be recruited and randomly assigned to an intervention group or a waitlist control group. The intervention group will receive six weekly 1.5-hour face-to-face NVC training sessions delivered by trained social workers.\n\nFive to ten social workers will be trained by professional NVC trainers through a train-the-trainer workshop, including three sessions. Each social worker will be assessed before (TTT1), after (TTT2) the workshops and 10 months (TTT3).\n\nAssessments for participants will be conducted at baseline (T1), immediately post-intervention (T2), and at three-month follow-up (T3). After completing the assessments, the waitlist control group will receive the same sessions. Qualitative interviews will be conducted to explore participants' experiences and perceptions of NVC.",[135,394,31],"Depression Symptom",[396,397,398,135],"Nonviolent Communication","parents","Depressive Symptoms","2025-09-11",{"date":401,"type":42},"2025-09-17",{"date":403,"type":42},"2025-05-01",{"date":405,"type":22},"2026-06-30",{"name":407,"class":49},"Hong Kong Metropolitan University",{"id":409,"slug":410,"hasResults":11,"nctId":411,"briefTitle":412,"officialTitle":413,"acronym":4,"eligibilityCriteria":414,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":415,"targetDuration":4,"studyType":23,"phases":417,"briefSummary":418,"conditions":419,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":425,"lastUpdatePostDateStruct":426,"startDateStruct":428,"completionDateStruct":430,"leadSponsor":432,"locationsCount":50},"100606109","yoga-asana-chandra-harmoni-on-psychological-well-being-and-learning-readiness-among-medical-students-100606109","NCT07171268","Yoga Asana Chandra Harmoni on Psychological Well-being and Learning Readiness Among Medical Students","A Randomized Controlled Trial of Yoga Asana Chandra Harmoni on Psychological Well-being and Learning Readiness Among Medical Students","Inclusion Criteria:\n\n* 3rd-year medical student\n* Willing to attend yoga sessions and practice at home.\n* Willing to provide consent and complete assessments.\n\nExclusion Criteria:\n\n* Regular yoga practice (≥ 6 months).\n* Physical contraindications to yoga.\n* Active treatment for severe mental health disorder.\n* Concurrent participation in another intervention study.",{"count":416,"type":22},80,[25],"The goal of this trial is to learn if the Yoga Asana Chandra Harmoni intervention can improve psychological well-being and learning readiness in medical students. The main questions it aims to answer are:\n\nDoes Yoga Asana Chandra Harmoni improve psychological well-being (specifically, reduce stress, anxiety, and depression) in medical students? Does Yoga Asana Chandra Harmoni enhance self-directed learning readiness in medical students? Researchers will compare a group receiving the Yoga Asana Chandra Harmoni intervention to a control group to see if the intervention leads to significant improvements in psychological well-being and self-directed learning readiness.\n\nParticipants will:\n\nComplete baseline questionnaires assessing psychological well-being, sleep quality, self-directed learning readiness, and self-efficacy.\n\nParticipate in 3 weekly Yoga Asana Chandra Harmoni sessions for 4 weeks (intervention group).\n\nContinue with their usual activities (control group). Complete follow-up questionnaires at post-test (end of week 4) and at a 2-week follow-up to assess changes in the outcome measures.\n\nEngage in additional online audio guided practices 5 times\u002Fweek for 20-30 minutes, including breathing exercises (weeks 1-2) and body scans (weeks 3-4) (intervention group).",[420,421,69,422,423,424],"Yoga","Yoga Exercises","Self Efficacy","Medical Student","Health and Wellness","2025-09-10",{"date":427,"type":42},"2025-09-12",{"date":429,"type":22},"2025-12-30",{"date":431,"type":22},"2026-03-01",{"name":433,"class":49},"Gadjah Mada University",{"id":435,"slug":436,"hasResults":11,"nctId":437,"briefTitle":438,"officialTitle":438,"acronym":439,"eligibilityCriteria":440,"healthyVolunteers":16,"sex":17,"minAge":441,"maxAge":18,"enrollmentInfo":442,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":444,"conditions":445,"keywords":452,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":460,"lastUpdatePostDateStruct":461,"startDateStruct":463,"completionDateStruct":465,"leadSponsor":467,"locationsCount":50},"100561829","community-park-based-programs-for-health-promotion-fit2play-prospective-cohort-study-100561829","NCT06595251","Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study","F2P","Inclusion Criteria:\n\n* All participants enrolled in the Miami-Dade Fit2Play study will be included in this secondary analysis\n\nExclusion Criteria:\n\n* Anyone not enrolled in the Miami-Dade Fit2Play study will be excluded from this secondary analysis","6 Years",{"count":443,"type":22},5000,"The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Play prospective cohort study run by Miami-Dade County Parks and Recreation.",[446,447,448,449,135,31,267,450,451],"Overweight","Obesity","Hypertension","Prehypertension","Low Physical Fitness","Psychological",[453,454,455,456,457,458,459],"Youth","Afterschool","Parks and Recreation","Mental Health","Physical Health","Physical Activity","Exercise","2025-09-03",{"date":462,"type":42},"2025-09-04",{"date":464,"type":42},"2020-05-07",{"date":466,"type":22},"2027-05-17",{"name":468,"class":49},"Duke University",{"id":470,"slug":471,"hasResults":11,"nctId":472,"briefTitle":473,"officialTitle":474,"acronym":4,"eligibilityCriteria":475,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":476,"enrollmentInfo":477,"targetDuration":4,"studyType":23,"phases":479,"briefSummary":480,"conditions":481,"keywords":483,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":494,"lastUpdatePostDateStruct":495,"startDateStruct":497,"completionDateStruct":499,"leadSponsor":501,"locationsCount":50},"100603720","impact-of-a-physical-activity-intervention-on-sleep-quality-mental-and-physical-well-being-in-health-sciences-students-100603720","NCT07140185","Impact of a Physical Activity Intervention on Sleep Quality, Mental and Physical Well-Being in Health Sciences Students","Evaluation of a Physical Activity Intervention on Sleep Quality, Mental and Physical Well-Being in Health Sciences Students: A Randomized Controlled Trial Comparing Regular Weekly Activity With a \"Weekend Warrior\" Pattern","Inclusion Criteria:\n\n* Aged 18 to 25 years.\n* Low level of physical activity, determined using the validated International Physical Activity Questionnaire (IPAQ) according to its scoring thresholds.\n* Provided written informed consent.\n* Available to participate in the entire intervention program and all planned assessments.\n\nExclusion Criteria:\n\n* Current use of medications that may affect sleep quality or alertness (e.g., sedative hypnotics, sedative antidepressants, psychostimulants).\n* History of serious medical conditions or any contraindication to moderate physical activity.\n* Morbid obesity.\n* Current pregnancy during the study period.\n* Participation in another intervention program simultaneously.","25 Years",{"count":478,"type":22},100,[25],"This randomized controlled trial aims to compare the effects of a regular weekly physical activity program versus a \"Weekend Warrior\" activity pattern on sleep quality, physical well-being, and mental well-being in sedentary university students. Participants will be randomly assigned to one of the intervention groups or to a control group and assessed at baseline and after the intervention.",[363,482,458,31],"Sedentary Lifestlye",[484,485,486,487,488,489,490,491,492,493],"Sedentary lifestyle","University students","Physical activity","Exercise intervention","Weekend Warrior","Sleep quality","well-being","Mental health","Fatigue","Randomized controlled trial","2025-08-21",{"date":496,"type":42},"2025-08-24",{"date":498,"type":22},"2025-09-15",{"date":500,"type":22},"2025-12-20",{"name":502,"class":49},"University of Sfax",{"id":504,"slug":505,"hasResults":11,"nctId":506,"briefTitle":507,"officialTitle":508,"acronym":4,"eligibilityCriteria":509,"healthyVolunteers":11,"sex":510,"minAge":129,"maxAge":60,"enrollmentInfo":511,"targetDuration":4,"studyType":23,"phases":513,"briefSummary":514,"conditions":515,"keywords":523,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":533,"lastUpdatePostDateStruct":534,"startDateStruct":536,"completionDateStruct":538,"leadSponsor":539,"locationsCount":50},"100603856","yoga-in-women-with-surgical-menopause-after-gynecological-cancer-100603856","NCT07141953","Yoga in Women With Surgical Menopause After Gynecological Cancer","The Effect of Yoga on Quality of Life, Sleep Quality, and Spiritual Well-Being in Women Who Undergo Surgical Menopause Following Gynecological Cancer Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\nAge between 18-65 years Diagnosis of primary gynecological cancer (ovarian, endometrial, cervical, vaginal, or vulvar) (Stage I-III) Ability to read, understand, and speak Turkish Completion of all adjuvant treatments (surgery, chemotherapy, and\u002For radiotherapy) at least 6 months prior Access to the internet Having a computer\u002Ftablet\u002Fphone with a camera Willingness and ability to attend at least 80% of the yoga sessions Voluntary participation in the study\n\nExclusion Criteria:\n\nAny condition that prevents communication Cognitive, sensory, or physical impairment that prevents yoga practice Diagnosis of metastatic gynecological cancer Regular yoga practice within the last 6 months (at least once a week for 8 consecutive weeks)","FEMALE",{"count":512,"type":22},46,[25],"This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery. Yoga is expected to be a supportive intervention for symptom management and to improve overall well-being in this patient population.",[516,517,518,519,520,521,363,31,420,522],"Gynecological Oncology","Gynecology","Oncology","Surgical Menopause","Symptom Management","Quality of Life","Yoga for Cancer",[524,525,526,527,528,529,530,490,531,532],"gynecological oncology","gynecology","oncology","surgical menopause","symptom management","quality of life","sleep quality","yoga","yoga for cancer","2025-08-19",{"date":535,"type":42},"2025-08-26",{"date":537,"type":22},"2025-09-01",{"date":147,"type":22},{"name":540,"class":49},"Dokuz Eylul University",{"id":542,"slug":543,"hasResults":11,"nctId":544,"briefTitle":545,"officialTitle":546,"acronym":547,"eligibilityCriteria":548,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":549,"enrollmentInfo":550,"targetDuration":4,"studyType":23,"phases":552,"briefSummary":553,"conditions":554,"keywords":558,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":567,"lastUpdatePostDateStruct":568,"startDateStruct":570,"completionDateStruct":572,"leadSponsor":574,"locationsCount":50},"100593709","an-exploratory-feasibility-study-100593709","NCT07009964","An Exploratory Feasibility Study","AI-Enhanced Educational Intervention to Support Contextual Well-being in Young Adults (ContextWell)","Contextwell","Inclusion Criteria:\n\nPrimarily healthcare students, young adults enrolled in higher education (18-30 years old)\n\nAccess to a computer or mobile device with an internet connection;\n\nWillingness to participate in the educational webinar;\n\nWillingness to complete AI-driven assignments;\n\nAble to read and understand English.\n\nExclusion Criteria:\n\nAre under the age of 18, or above 30;\n\nInability to access a computer or mobile device with internet connection;\n\nInability to read or understand English;\n\nUnwillingness to participate in the webinar or complete assignments.","30 Years",{"count":551,"type":22},12,[25],"This study explores the feasibility of ContextWell, a well-being education programme that combines an online webinar with an AI-powered behavioural nudging system. The programme aims to support university students, particularly those in healthcare disciplines, in enhancing well-being and adopting healthier lifestyle habits.\n\nThe primary objective is to determine whether the programme can be feasibly delivered within university settings. A secondary objective is to assess its potential to improve student well-being and encourage behavioural changes aligned with lifestyle medicine principles.\n\nThe intervention builds on the understanding that healthcare professionals' lifestyle habits and well-being have a direct impact on patient care. Focusing on healthcare students helps advance the integration of lifestyle medicine within health education and clinical practice.\n\nThis single-group feasibility study delivers the full intervention to all participants. Students participate in an online well-being webinar and receive AI-generated behavioural prompts designed to promote self-awareness and healthier daily choices.\n\nKey evaluation measures will indicated the feasibility of the programme among young adults in academic environments. Participant feedback and initial outcomes will support future development and inform larger-scale research.",[136,555,556,557],"Lifestyle, Healthy","Young Adult","Behavior and Behavior Mechanisms",[559,110,560,561,562,563,564,565,566],"Student well-being","Contextual Well-being","Contextual AI","Preventive health","Digital Health","Lifestyle medicine","Pilot study","Proof of concept","2025-06-18",{"date":569,"type":42},"2025-06-19",{"date":571,"type":22},"2025-11-01",{"date":573,"type":22},"2026-02-01",{"name":575,"class":49},"University College Dublin",{"id":577,"slug":578,"hasResults":11,"nctId":579,"briefTitle":580,"officialTitle":581,"acronym":582,"eligibilityCriteria":583,"healthyVolunteers":11,"sex":17,"minAge":129,"maxAge":584,"enrollmentInfo":585,"targetDuration":4,"studyType":23,"phases":587,"briefSummary":588,"conditions":589,"keywords":598,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":609,"lastUpdatePostDateStruct":610,"startDateStruct":612,"completionDateStruct":614,"leadSponsor":616,"locationsCount":120},"100581602","troubled-desire--therapeutic-chat-for-reduction-of-csam-use-td-chat-100581602","NCT06852443","Troubled-Desire & Therapeutic Chat for Reduction of CSAM Use (TD-CHAT)","Troubled Desire & Therapeutic Chat for Reduction of CSAM Use","TD-CHAT","Inclusion Criteria:\n\n* Adult participant (≥18 years);\n* recent (last 2 weeks) CSAM use or past CSAM use and self-reported risk;\n* proficiency in English, German or Spanish;\n* voluntary participation and agreement to the terms of the study.\n\nExclusion Criteria:\n\n* Severe neuropsychiatric comorbidities (unstable psychotic disorder, organic brain damage, diminished intellectual functioning, untreated drug or alcohol addiction);\n* history of contact CSA perpetration (past or present);\n* ongoing criminal investigation, trial, punishment, or probation status for online or offline CSA or CSAM use;\n* current inpatient psychiatric treatment or other concurrent treatment targeting CSAM behaviours","99 Years",{"count":586,"type":22},180,[25],"The goal of this prospective multicentred, stratified, parallel-group superiority study is to prevent and reduce the usage of Child Sexual Abuse Material (CSAM) by a Therapist Chat Service (TCS) and Selfhelp Platform for Self-Referred Patients, mostly men with a sexual interest in children. The interventions are based on Cognitive Behavioral Therapy (CBT) principles and designed to treat the sexual behavioral disorder related with CSAM consumption.\n\n1. Participants in the Selfhelp modules group will show a statistically significantly higher proportion of reduction in CSAM behaviours four weeks after baseline, as compared to participants in the waitlist control group.\n2. Participants in the Selfhelp modules followed by TCS group will show a statistically significantly higher reduction of CSAM behaviours compared to participants in the Selfhelp-only and TCS-only groups, post-intervention.\n\nResearchers will compare TCS-only-, Selfhelp-only-, Selfhelp + TCS- and Waiting group to see if if the interventions decrease CSAM use and improve mental well-being.\n\nParticipants will get web based selfhelp-modules and\u002For text-based chat intervention operated by trained therapists.",[590,69,591,592,593,594,595,596,597],"Prevention","Sexual Behavior","Behavior Change","Behavior Problems","Behavior Change Interventions","Child Sexual Abuse Material (CSAM) Consumption","Behavioral Disorder","Online Behaviour",[599,600,601,602,603,604,605,606,607,608],"Child Sexual Abuse Material (CSAM) consumption","CSAM","Child Sexual Abuse","Digital online intervention","CSA","CBT","iCBT","Cognitive Behavioural Therapy","Pedophilia","chat Intervention","2025-05-06",{"date":611,"type":42},"2025-05-07",{"date":613,"type":42},"2025-04-01",{"date":615,"type":22},"2026-07-31",{"name":617,"class":49},"Charite University, Berlin, Germany",{"id":619,"slug":620,"hasResults":11,"nctId":621,"briefTitle":622,"officialTitle":622,"acronym":623,"eligibilityCriteria":624,"healthyVolunteers":11,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":625,"targetDuration":4,"studyType":23,"phases":626,"briefSummary":627,"conditions":628,"keywords":631,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":634,"lastUpdatePostDateStruct":635,"startDateStruct":637,"completionDateStruct":639,"leadSponsor":641,"locationsCount":643},"100376021","intensive-care-unit-resident-scheduling-trial-100376021","NCT04176094","Intensive Care Unit Resident Scheduling Trial","InCURS","Inclusion Criteria for ICUs:\n\n* Admit adult patients (≥18 years);\n* Are anticipated to have sufficient rotating residents from Royal College of Physicians and Surgeons of Canada -accredited training programs to provide overnight in-house coverage for at least 20 overnight periods in 28 days; and\n* Are willing to participate in the study (schedule randomization, measurements).\n\nInclusion Criteria for Patients:\n\n• Patients admitted to ICU during either period of the study.\n\nInclusion Criteria for Residents:\n\n* Are enrolled in an accredited specialty training program of the Royal College of Physicians and Surgeons of Canada (internal or emergency medicine, surgery, anaesthesia, other, but not critical care medicine),\n* Are able to perform overnight in-house duty with supervision from critical care trainees and intensivists, and\n* Have the first 4 weeks of their ICU rotation entirely in one period. Residents who have participated in the study previously will not complete the competency assessments, however will be eligible to participate in the wellbeing and description of learning activities.\n\nInclusion Criteria for Supervisors:\n\n• Are Physicians responsible for the supervision of residents and other trainees in the ICU, and include Critical Care Trainees and Staff Physicians.\n\nInclusion Criteria for ICU frontline staff:\n\n• Are Registered nurses, registered respiratory therapists, pharmacists, social workers, physiotherapists and occupational therapists, who provide care in the ICU.\n\nExclusion Criteria for ICUs:\n\n* ICUs with no rotating residents performing overnight in-house duty.\n* ICUs that are anticipating a major change in ICU staffing (e.g. in-house intensivist added or removed, in-house fellow added or removed) or\n* Are unwilling to have either resident schedule randomized, to provide study measurements or both.\n\nExclusion Criteria for Patients:\n\n• Patients will be excluded if they are in the ICU at the start of a study period.\n\nExclusion Criteria for Residents:\n\n* Residents enrolled in a critical care medicine accredited specialty training program,\n* Who are not able to perform overnight in-house duty,\n* Where the first 4 weeks of their ICU rotation are not in one period,\n* Where the length of their ICU rotation is less than 4 week.",{"count":62,"type":22},[25],"Many patients, doctors and others worry that tired doctors provide worse patient care, may not learn well and become burnt-out. In response to these concerns, some countries changed their laws to limit work-hours for doctors in training ('residents').\n\nIn Canada, most residents work six or seven 24-30h shifts each month. A recent Canadian report ordered by Health Canada said that making good decisions about resident work-hour rules was \"significantly limited by quality evidence, especially evidence directly attributable to the Canadian context.\" Creating this evidence is the main goal of this research.\n\nThe pilot study in 2 intensive care units(ICU) found that shorter shifts may be worse for patients, and for residents were more tiring than expected but improved wellbeing. Learning was not assessed. Previous studies on resident work-hours report similar findings: conflicting effects for patients, benefits for resident wellbeing, inconsistent and under-studied effects on learning. Overall, these results are not conclusive and confirm the need for a larger study.\n\nThe current study will provide high-quality Canadian evidence. The investigators will compare two common ICU schedules used in Canada: resident shifts of 16h and 24h. ICU patients are very sick, there is little margin for error: they need doctors who know them well and are thinking clearly.\n\nThe effects of each schedule on patients and residents will be measured. For patients, mortality rates and harm caused by care in ICU will be studied. For resident education, their learning about managing common illnesses in ICU, to do basic ICU procedures, and communicate with families will be studied. For resident wellbeing measures will include sleepiness, other fatigue symptoms, and burnout.\n\nInvestigators will study both resident and patient outcomes so that Canadians can understand trade-offs linked to changing schedules. With this knowledge, Canadians can expect safer care for today's patients and better-trained doctors for the patients of tomorrow.",[629,31,630],"Patient Safety","Education",[632,633],"health service and systems research","population health","2025-04-08",{"date":636,"type":42},"2025-04-11",{"date":638,"type":42},"2019-11-18",{"date":640,"type":22},"2027-12",{"name":642,"class":49},"The Hospital for Sick Children",5,{"id":645,"slug":646,"hasResults":11,"nctId":647,"briefTitle":648,"officialTitle":649,"acronym":4,"eligibilityCriteria":650,"healthyVolunteers":16,"sex":17,"minAge":651,"maxAge":652,"enrollmentInfo":653,"targetDuration":4,"studyType":23,"phases":655,"briefSummary":656,"conditions":657,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":659,"lastUpdatePostDateStruct":660,"startDateStruct":662,"completionDateStruct":664,"leadSponsor":666,"locationsCount":50},"100578755","inforcing-spiritual-care-enhancing-well-being-and-competency-in-psychiatric-nurses-100578755","NCT06815419","Inforcing Spiritual Care: Enhancing Well-Being and Competency in Psychiatric Nurses","In Forcing Spiritual Care: Enhancing Well-Being and Competency in Psychiatric Nurses","Inclusion Criteria:\n\nThe participants of this study were 98 psychiatric nurses working in previously mentioned psychiatric settings and who fulfilled the following inclusion criteria as both male and female, had one year of experience in psychiatric care, willingness to participate in the study and provide informed consent and did not enroll in any ongoing spiritual care-related training.\n\nExclusion Criteria:\n\nNurses refused to participate Nurses not on the full duty","20 Years","60 Years",{"count":654,"type":22},98,[25],"This study was done to evaluate the effectiveness of spiritual care education program in enhancing the well-being and competency of psychiatric nurses.",[31,658],"Competence","2025-02-03",{"date":661,"type":42},"2025-02-07",{"date":663,"type":22},"2025-02-10",{"date":665,"type":22},"2025-03-01",{"name":667,"class":49},"Port Said University",{"id":669,"slug":670,"hasResults":11,"nctId":671,"briefTitle":672,"officialTitle":672,"acronym":4,"eligibilityCriteria":673,"healthyVolunteers":11,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":674,"targetDuration":4,"studyType":23,"phases":676,"briefSummary":677,"conditions":678,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":679,"lastUpdatePostDateStruct":680,"startDateStruct":682,"completionDateStruct":684,"leadSponsor":686,"locationsCount":50},"100566248","addressing-the-mental-health-and-emotional-well-being-of-immigrants-through-a-scalable-intervention-100566248","NCT06652711","Addressing the Mental Health and Emotional Well-being of Immigrants Through a Scalable Intervention","The target population will be: immigrants to the U.S. of Hispanic origin whose native language is Spanish, who have been living in the U.S. (intermittently or continuously) for less than 10 years, who are over 18 years of age, who have a PHQ4 score that is three or more, who would be interested in using a well-being phone app, who do not have a graduate degree and have access to a smartphone.",{"count":675,"type":22},2100,[25],"We will study the impacts of offering access to an emotional well-being phone app to Hispanic U.S. immigrants in psychological distress. Our primary outcome is participants' psychological well-being.",[31,456],"2024-10-21",{"date":681,"type":42},"2024-10-22",{"date":683,"type":42},"2024-09-20",{"date":685,"type":22},"2025-09",{"name":687,"class":49},"University of Texas at Austin",{"id":689,"slug":690,"hasResults":11,"nctId":691,"briefTitle":692,"officialTitle":692,"acronym":4,"eligibilityCriteria":693,"healthyVolunteers":16,"sex":17,"minAge":129,"maxAge":4,"enrollmentInfo":694,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":696,"conditions":697,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":700,"lastUpdatePostDateStruct":701,"startDateStruct":703,"completionDateStruct":705,"leadSponsor":707,"locationsCount":50},"100563818","focus-group-study-on-the-feeling-tone-mindfulness-course-100563818","NCT06621108","Focus Group Study on the Feeling Tone Mindfulness Course","Inclusion Criteria:\n\n* Aged 18 or above\n* Speak and understand Cantonese as well as written Chinese to a level where the participant can fully take part in the focus group session without the need for translation support\n* Have means to access online teleconferencing meeting software (e.g., Zoom), online surveys (to give their informed consent and to schedule a focus group session), online materials, and Short Message Service (SMS) or WhatsApp messenger.\n* Participants who have completed the four-week feeling tone mindfulness course\n\nExclusion Criteria:\n\n* N\u002FA",{"count":695,"type":22},25,"This is an academic research study aiming to explore the acceptability, feasibility, and effectiveness of a four-week feeling tone mindfulness course by gathering qualitative feedback from course participants in a focus group format.",[268,698,267,135,699,31],"Self-Compassion","Stress","2024-09-29",{"date":702,"type":42},"2024-10-01",{"date":704,"type":22},"2024-10",{"date":706,"type":22},"2026-12",{"name":708,"class":49},"The University of Hong Kong"]