[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wellbeing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wellbeing":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,20,0,[8,57,80,105,137,158,199,224,250,278,320,347,378,405,441,474,501,525,547,583],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":38,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100604558","tag-team---trans-adolescent-group-therapy-100604558",false,"NCT07151079","TAG TEAM - Trans Adolescent Group Therapy","Evaluation of Trans Adolescent Group ThErapy for Alleviating Minority Stress (TAG TEAM): a Randomised Controlled Trial","TAG TEAM","Participants will be enrolled into the RCT only if they meet all the inclusion criteria and none of the exclusion criteria.\n\nInclusion Criteria:\n\n* Identifies as trans, non-binary, or gender diverse\n* Is between the ages of 12 and 17 years inclusive\n* Has completed primary school at the time of enrolment into the study\n* Has current psychological stress symptomology as determined by a score of moderate or above on the DASS-Y\n* Provide informed consent: All participants and parent\u002Flegal guardians must be willing to give informed consent\n\nExclusion Criteria:\n\n* Has current acute suicidal symptomology as determined by a combination of clinical judgement and the results of the Ask Suicide-Screening Questions (ASQ) suicide screening tool (e.g., answer yes to question 5) to determine the risk of suicide (has an active plan and\u002For intent to suicide) at time of screening interview\n* Is actively having treatment with any other group psychological intervention at the time of enrolment into the study\n* Is not proficient in English (as the group Cognitive behaviour therapy (CBT) program will be delivered in English and funds aren't available for interpreters)\n* Previous participation in the feasibility trial\n* Is currently enrolled in tertiary study (e.g., undergraduate university)","ALL","12 Years","17 Years",{"count":21,"type":22},142,"ESTIMATED","INTERVENTIONAL",[25],"NA","This project will study the effect of the TAG TEAM group CBT program on the mental health of trans and gender diverse adolescents. TAG TEAM was co-designed by researchers and clinicians with a group of trans and gender diverse young people to help trans and gender diverse adolescents understand and cope with minority stress. Minority stress includes experiences like discrimination and rejection. TAG TEAM focuses on learning and practicing skills to support mental health and wellbeing. It also includes group discussions and activities with other trans and gender diverse young people. TAG TEAM groups are run by a psychologist and a trans peer facilitator. A trans peer facilitator is a trans and gender diverse person who is there to share their experience of being trans and to support participants in the group sessions.",[28,29,30,31,32,33,34,35,36,37],"Minority Stress","Acceptability","Psychological Distress","Anxiety","Depression in Adolescence","Coping","Wellbeing","Pride","Internalised Stigma","Community Connection",[39,40,41,34,42,43],"Adolescent","Trans and gender diverse","Minority stress","Group Therapy","CBT","RECRUITING","2026-06-04",{"date":47,"type":48},"2026-06-05","ACTUAL",{"date":50,"type":48},"2026-05-21",{"date":52,"type":22},"2027-03",{"name":54,"class":55},"Murdoch Childrens Research Institute","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":65,"targetDuration":4,"studyType":23,"phases":67,"briefSummary":68,"conditions":69,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":56},"100640041","evaluating-a-workbook-to-promote-autistic-wellbeing-100640041","NCT07630376","Evaluating a Workbook to Promote Autistic Wellbeing","Evaluating the Use of a Guided Self-help Workbook to Promote Wellbeing for Autistic Adults: A Mixed-methods Multiple Single-case Study","Inclusion Criteria:\n\n* A pre-existing diagnosis of autism OR on a waiting list for autism assessment OR self-identified as autistic and scoring above cut-off on the autism quotient (AQ-50) screening questionnaire.\n* Aged 18 years or over and able to give informed consent to participate.\n* Under the care of a community-based mental health team in Kent and Medway Mental Health NHS Trust and not due for discharge during the study period.\n* Have already completed assessment processes (including risk assessment) during intake by the clinical team and a management plan is in place.\n* The named clinician assesses that the individual is in sufficiently stable condition to participate in the study, and is likely to remain engaged in the intervention.\n* Proficiency in reading and writing English.\n* If on medication for mental health, the dose is stable (minimum of 3 months) with no planned changes during the study.\n\nExclusion Criteria:\n\n* Presence of a moderate to severe learning disability that would limit independent engagement with self-help materials.\n* Engaged in another psychological therapy or psychologically-informed intervention, or due to begin another during the study.\n* Current acute mental health crisis or elevated risk to self\u002Fothers requiring intensive intervention (assessed via clinical team judgement).\n* Insufficient capacity to engage with the study protocol or complete measures (as determined by the care team).","18 Years",{"count":66,"type":22},10,[25],"The goal of this clinical trial is to examine the feasibility and acceptability of a brief guided self-help wellbeing intervention for autistic adults accessing UK secondary mental health services. The study also aims to begin to evaluate whether use of the workbook is associated with any changes in wellbeing. The main questions it aims to answer are:\n\n1. Is it feasible to recruit and retain autistic adults to participate in the study?\n2. Do participants find the workbook acceptable and relevant?\n3. Are there measurable improvements in wellbeing following workbook use?\n4. What changes, if any, do participants recommend for future versions of the intervention?\n\nParticipants will:\n\n* Take part in 4-6 sessions of 30-60 minutes using the guided self-help workbook with the support of a trained National Health Service support worker, assistant psychologist, or mental health professional\n* Complete wellbeing questionnaires before, during, and after using the workbook\n* Complete brief daily wellbeing ratings throughout the study\n* Take part in a 1:1 semi-structured interview of up to an hour to discuss their experience of the workbook",[70,34],"Autism","NOT_YET_RECRUITING","2026-06-01",{"date":47,"type":48},{"date":75,"type":22},"2026-06",{"date":77,"type":22},"2027-04",{"name":79,"class":55},"Canterbury Christ Church University",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":64,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100600902","initiative-for-chinese-sex-workers-to-promote-wellbeing-and-improve-hiv-prevention-by-reducing-intersectional-stigma-100600902","NCT07103525","Initiative for Chinese Sex Workers to Promote Wellbeing and Improve HIV Prevention by Reducing intersEctional Stigma","INSPIRE: Initiative for Chinese Sex Workers to Promote Wellbeing and Improve HIV Prevention by Reducing intersEctional Stigma","INSPIRE","Inclusion Criteria:\n\n* Female Sex Workers: A person who identifies as a woman, Chinese, a massage parlor (MP) worker in Queens, who is at least 18 years old, and has provided sexual services in the past 12 months, will be eligible.\n* Community advisory board (CAB) members: self identifies as a community member providing services to immigrant Chinese women and is at least 18 years old.\n* Peer Advocates: self identifies as current or previous sex worker, is a Chinese adult woman, and speaks both Mandarin and English.\n* Medical Providers: self identifies as a current medical provider who works with Chinese immigrant adults and speaks English.\n\nExclusion Criteria:\n\n* Female Sex Workers: Because completion of HIV testing is our primary study outcome, women who received an HIV test in the previous 3 months or who know they are HIV-positive will be excluded from the study.\n* Community advisory board (CAB) members: Does not speak English or is under the age of 18.\n* Peer Advocates: Does not speak English\u002FMandarin or is under the age of 18.\n* Medical Providers: Does not speak English or does not provide care to Chinese immigrant adults (e.g., pediatricians).",true,"FEMALE",{"count":91,"type":22},70,[25],"During the development phase (Aim 1), investigators will use a community-driven process to further refine a preliminary intervention design that was developed based on previous research.\n\nFor the intervention phase (Aim 2), investigators will conduct a pilot randomized controlled trial of the multi-level intervention. For the individual-level component of the intervention, investigators will recruit 70 Chinese immigrant FSWs who work in MPs in Queens, NYC (n=35 intervention participants and n=35 control participants).\n\nTo assess the feasibility and acceptability of intervention implementation (Aim 3), investigators will conduct in-depth qualitative interviews with 12 FSW study participants and the 2 peer advocates and focus groups with 4-5 staff from each of the 3 organizations (3 focus groups total and 12-15 focus group participants in total).",[95,34],"HIV Prevention","2026-05-28",{"date":98,"type":48},"2026-05-29",{"date":75,"type":22},{"date":101,"type":22},"2028-01",{"name":103,"class":55},"NYU Langone Health",3,{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":88,"sex":17,"minAge":113,"maxAge":64,"enrollmentInfo":114,"targetDuration":4,"studyType":23,"phases":116,"briefSummary":117,"conditions":118,"keywords":123,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":133,"leadSponsor":135,"locationsCount":4},"100635847","many-trauma-affected-youth-face-long-waits-for-therapy-worsening-stress-and-avoidance-ciss-a-90-minute-session-based-on-stanfords-cue-centered-therapy-offers-coping-tools-and-psychoeducation-during-this-gap-this-pilot-tests-cisss-feasibility-acceptability-and-impact-on-30-40-adolescents-100635847","NCT07558005","Many Trauma-affected Youth Face Long Waits for Therapy, Worsening Stress, and Avoidance. CISS, a 90-minute Session Based on Stanford's Cue-Centered Therapy, Offers Coping Tools and Psychoeducation During This Gap. This Pilot Tests CISS's Feasibility, Acceptability, and Impact on 30-40 Adolescents.","CISS: CCT-Informed Single Session Intervention","CISS","Inclusion Criteria:\n\n* Age: 13 to 18 years old (adolescents).\n\nTrauma Exposure: History of chronic or single-event trauma (e.g., interpersonal violence, serious accidents, natural disaster) as documented in Child and Adolescent Mental Health Services (CAMHS) intake records.\n\nService Status: Currently on a CAMHS waitlist for trauma-focused therapy, or self-referred but hesitant to begin multi-session treatment.\n\nCapacity and Consent: Ability to provide informed assent (ages 13-15 with parental permission) or informed consent (ages 16-18).\n\nExclusion Criteria:\n\nCurrent Trauma Treatment: Actively engaged in any form of trauma-focused psychotherapy (e.g., TF-CBT, EMDR, CCT) at the time of enrollment.\n\nSevere Cognitive Impairment: Intellectual disability or cognitive impairment (e.g., IQ \\\u003C 70) that precludes comprehension of psychoeducational material or completion of self-report questionnaires.\n\nAcute Suicidality: Endorsement of imminent self-harm or suicide risk (e.g., PHQ-9 item 9 ≥ 2) during screening that necessitates immediate crisis management rather than study participation.","13 Years",{"count":115,"type":22},40,[25],"Many young people who have experienced traumatic events such as sexual assault, domestic violence, serious accidents, or natural disasters face long waits before they can begin full trauma-focused therapy. During this waiting period, symptoms such as avoidance, anxiety, and distress may worsen, and many youth lose motivation or confidence to start treatment. The Cue-Centered Therapy (CCT)-Informed Single Session Intervention (CISS) was designed to bridge this gap by offering a one-time, 90-minute session that teaches coping and self-understanding skills while youth are still on the waiting list.\n\nThis study is a pilot feasibility trial conducted in partnership between Stanford University and the University of Auckland. The purpose of the study is to evaluate whether CISS is a practical, acceptable, and safe intervention for young people aged 13-18 who have been exposed to trauma and are currently waiting for or hesitant to begin full-length therapy within New Zealand Hapai Ora Clinics.\n\nYouth participants will meet once with a trained Hapai Ora clinician who will deliver the 90-minute CISS session. The session combines psychoeducation about trauma cues with skill-building strategies to improve coping, confidence, and readiness to engage in future treatment. Participants will complete short questionnaires before and after the session, and again at 3- and 6-month follow-ups. Measures will assess coping self-efficacy, treatment readiness, posttraumatic stress symptoms, and whether participants eventually begin full-length therapy.\n\nThe study will recruit approximately 30-40 adolescents across Hapai Ora clinical sites in Auckland, New Zealand. All clinicians providing the intervention are qualified mental-health professionals trained in both CISS and child-safety protocols. Participation involves minimal risk-similar to discussing difficult topics in a supportive therapy session.\n\nFindings from this pilot study will help researchers understand whether CISS can be feasibly and safely delivered within public mental-health services, and whether it shows promise in helping young people build coping skills, reduce avoidance, and increase readiness to start therapy. The results will guide future larger-scale trials and inform the development of single-session, early-intervention approaches for trauma-exposed youth worldwide.",[34,119,120,121,122],"Mental Health","Psychological","Stress","Trauma Exposure",[124,111,125,126,127,128],"Trauma Intervention","Cue Centered Therapy (CCT)","Single-Session Intervention","Chronic Trauma","Trauma","2026-04-22",{"date":131,"type":48},"2026-04-30",{"date":72,"type":22},{"date":134,"type":22},"2028-11-30",{"name":136,"class":55},"Stanford University",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":23,"phases":146,"briefSummary":147,"conditions":148,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":56},"100633255","self-help-plus-pilot-study-colombia-train2care-100633255","NCT07524309","Self-Help Plus Pilot Study, Colombia: Train2Care","Self-Help Plus Pilot Study, Colombia: Training to Care: Global Mental Health With a Territorial Approach","T2C","Inclusion Criteria:\n\n* 18 years old and living in the study area\n\nExclusion Criteria:\n\n* Current risk of self-harm or suicide that requires a higher level of care\n* Significant cognitive impairment that would interfere with the ability to participate in the intervention or provide informed consent\n* Severe mental health conditions requiring specialized care (for example, psychosis)\n* Severe substance use or substance use disorders that would interfere with participation or require specialized treatment",{"count":115,"type":22},[25],"This project will strengthen local capacity for mental health care in high-need settings in Colombia by culturally and linguistically adapting the Self-Help+ intervention and delivering participatory, supervised training. Local community leaders will be trained to implement Self Help+ for their own well-being and to train others in their communities. The project will deliver a structured program with hands-on practice, ongoing technical support, and participatory evaluation of psychosocial outcomes and sustainability.",[34],"2026-04-06",{"date":151,"type":48},"2026-04-13",{"date":153,"type":22},"2026-05-15",{"date":155,"type":22},"2026-10-31",{"name":157,"class":55},"George Washington University",{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":23,"phases":168,"briefSummary":169,"conditions":170,"keywords":174,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":198},"100630933","aurora-ai-based-narrative-intervention-to-support-emotional-well-being-in-clinical-and-non-clinical-populations-100630933","NCT07494110","Aurora: AI-Based Narrative Intervention to Support Emotional Well-Being in Clinical and Non-Clinical Populations","Aurora: Evaluation of an AI-Based Narrative Intervention for Emotional Well-Being, Identity Processes, and Recovery-Oriented Outcomes in Clinical and Non-Clinical Populations","Aurora","Inclusion Criteria\n\nArm 1: Healthy Adults (Single-Session Intervention)\n\nAge 18 years or older at screening.\n\nSufficient ability to read and understand Spanish to follow study instructions and complete questionnaires.\n\nAbility to engage in a brief guided interaction and complete self-report measures.\n\nAble and willing to provide written informed consent.\n\n\\---\n\nArm 2: Adults with DSM-5 Diagnosed Mental Disorder in Residential Care (4-hour Intervention)\n\nAge 18 years or older at screening.\n\nCurrently residing in a participating long-term mental health residential care facility and expected to remain there for the duration of the intervention and post-assessment period.\n\nDocumented diagnosis of a mental disorder according to DSM-5 criteria, confirmed by the treating clinician.\n\nMinimal clinical stability at baseline, defined as all of the following:\n\nClinically stable in the judgment of the treating clinician.\n\nNo requirement for acute psychiatric hospitalization or crisis intervention in the previous 4 weeks.\n\nClinical Global Impression - Improvement (CGI-I) score between 3 and 5 inclusive during the 4 weeks prior to enrollment, indicating relative clinical stability.\n\nSufficient ability to understand spoken and written Spanish to participate in study procedures.\n\nAbility to engage in guided interaction and provide feedback.\n\nAble and willing to provide informed consent; when applicable, provision of legal guardian consent plus participant assent.\n\nWillingness to participate in all study procedures.\n\n\\---\n\nArm 3: Healthy Older Adults (≥65 Years; 4-hour Intervention)\n\nAge 65 years or older at screening.\n\nNo self-reported diagnosis of a serious mental disorder (for example, psychotic disorder or bipolar disorder).\n\nSufficient ability to read and understand Spanish to participate in study procedures.\n\nAdequate cognitive and communication abilities to engage in guided interaction and complete questionnaires.\n\nAble and willing to provide written informed consent.\n\n\\---\n\nExclusion Criteria\n\nArm 1: Healthy Adults\n\nCurrent acute medical or psychiatric condition that would compromise safe participation or data validity.\n\nModerate or high acute suicide or self-harm risk at screening.\n\nSignificant cognitive, communication, or comprehension impairment that would interfere with participation.\n\nExplicit refusal to participate.\n\n\\---\n\nArm 2: Adults with DSM-5 Diagnosed Mental Disorder in Residential Care\n\nCurrent acute psychiatric decompensation requiring crisis-level care.\n\nModerate or high acute suicide or self-harm risk at screening or baseline.\n\nHigh risk of clinically significant emotional harm from autobiographical life review, defined as treating clinician judgment that narrative or reminiscence work is contraindicated due to one or more of the following:\n\nSevere clinical destabilization within the past 3 months.\n\nTrauma-related re-experiencing symptoms.\n\nMarked dissociative symptoms.\n\nInability to provide informed consent, with no legal representative available when required, or lack of participant assent when applicable.\n\nSignificant cognitive, communication, or comprehension impairment without available supports.\n\nExplicit refusal to participate.\n\nImminent discharge or transfer that would prevent completion of the intervention or post-assessment.\n\n\\---\n\nArm 3: Healthy Older Adults\n\nSelf-reported diagnosis of a serious mental disorder (for example, psychotic disorder or bipolar disorder).\n\nModerate or high acute suicide or self-harm risk at screening.\n\nCurrent acute medical or psychiatric condition that would compromise safe participation.\n\nSignificant cognitive, communication, or comprehension impairment that would interfere with participation.\n\nExplicit refusal to participate.",{"count":167,"type":22},55,[25],"Aurora is an interdisciplinary project evaluating a chatbot-mediated supportive care intervention designed to promote emotional expression, autobiographical meaning-making, identity processes, and emotional well-being through guided narrative reconstruction. The Aurora system provides a structured, person-centered storytelling process supported by generative AI and human facilitation. Under the supervision of a trained facilitator (licensed mental health professional), participants engage in guided reminiscence and storytelling sessions to co-create a personalized \"life book.\" The chatbot is not a diagnostic or treatment tool; rather, it is intended to support emotional expression, narrative reconstruction, and recovery-oriented processes. The study includes three non-randomized arms implemented sequentially: (1) a single-session arm of healthy adults focused on acceptability, usability, and emotional safety; (2) a four-hour intervention arm of adults with DSM-5 diagnosed mental disorders in residential care; and (3) a four-hour intervention arm of healthy older adults aged 65 years and older. Quantitative outcomes assess affect, mental well-being, and recovery-related constructs. Additional measures include usability, satisfaction, and qualitative feedback. Ecological momentary assessment (EMA) is conducted in Arms 2 and 3.",[171,172,119,34,173],"Institutionalization","Elderly","Aging",[175,176,177,178,179,180,181,182,183,184,185,186,187,188],"artificial intelligence","digital mental health","human-computer interaction","recovery","identity","autobiographical narrative","life story","reminiscence","wellbeing","storytelling","residential care","older adults","chatbot intervention","mental health","2026-03-19",{"date":191,"type":48},"2026-03-27",{"date":193,"type":48},"2026-02-12",{"date":195,"type":22},"2026-04-01",{"name":197,"class":55},"Universitat Autonoma de Barcelona",2,{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":206,"targetDuration":4,"studyType":208,"phases":4,"briefSummary":209,"conditions":210,"keywords":213,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":56},"100629604","capturing-parental-wellbeing-in-everyday-life-through-a-mobile-diary-app-100629604","NCT07476833","Capturing Parental Wellbeing in Everyday Life Through a Mobile Diary App","Parental Wellbeing in Everyday Life: Ecological Momentary Assessment Study on the Wellbeing of Parents of Children Aged 0 - 12 in Switzerland","Inclusion Criteria:\n\nParents living in Switzerland\n\n* with at least one child aged between 0 months - 11 years and 11 months\n* German-speaking\n* any form of parenting\n* any relationship status\n* any form of couples or other forms of cohabitation\n* No restrictions regarding nationality, wealth, external childcare, employment (full-time, part-time or homemaker) or similar characteristics.\n\nParticipants must have a smartphone with internet access to participate in the mobile diary study\n\nExclusion Criteria:\n\n* All Children \\> 11 years and 11 months of age\n* Not German speaking\n* Swiss nationality but living abroad\n* No smartphone with internet access",{"count":207,"type":22},300,"OBSERVATIONAL","This observational study investigates the wellbeing of parents in German-speaking Switzerland in everyday contexts using smartphone-based Ecological Momentary Assessment (EMA). Family caregiving can be both rewarding and burdensome, yet little is known about how parental wellbeing fluctuates in daily life and across caregiving situations. The study aims to examine momentary subjective wellbeing, caregiving activities, and contextual factors in natural settings. Participants complete repeated real-time assessments via a digital diary application five times a day over a 14-day study period. The study seeks to characterize within-person variability in parental wellbeing and identify contextual factors associated with positive and negative daily experiences.",[34,211,212],"Sleep","Support, Family",[214],"Parental Wellbeing","2026-03-12",{"date":217,"type":48},"2026-03-17",{"date":219,"type":22},"2026-03-01",{"date":221,"type":22},"2026-07-31",{"name":223,"class":55},"Eastern Switzerland University of Applied Sciences",{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":230,"targetDuration":4,"studyType":23,"phases":232,"briefSummary":233,"conditions":234,"keywords":235,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":56},"100620710","health-and-wellness-coaching-to-improve-thoracic-transplant-caregiver-self-efficacy-100620710","NCT07361159","Health and Wellness Coaching to Improve Thoracic Transplant Caregiver Self-Efficacy","Inclusion Criteria:\n\n* Aged 18 years or older\n* Primary caregivers of patients listed (active, deferred, or temporarily inactive) for lung, heart\u002Flung, or heart transplantation at Mayo Clinic in Rochester\n\nExclusion Criteria:\n\n* Individuals younger than 18 years old\n* Individuals who are non-English speaking, non-verbal, or extremely hard of hearing",{"count":231,"type":22},30,[25],"This is a pilot study examining the effects of telephonic health and wellness coaching on self-efficacy and caregiving burden for caregivers of patients awaiting heart or lung transplant.",[34],[236,237,238,239,240],"Health and Wellness Coaching","Thoracic Transplant","Caregivers","Caregiver Burden","Caregiver Self-efficacy","2026-01-28",{"date":243,"type":48},"2026-01-30",{"date":245,"type":48},"2025-11-18",{"date":247,"type":22},"2026-12-31",{"name":249,"class":55},"Mayo Clinic",{"id":251,"slug":252,"hasResults":11,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":256,"eligibilityCriteria":257,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":258,"targetDuration":4,"studyType":23,"phases":259,"briefSummary":260,"conditions":261,"keywords":264,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":56},"100600442","change-in-social-media-use-and-well-being-among-college-students-receiving-a-two-week-exercise-or-mindfulness-intervention-100600442","NCT07097545","Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention","Social Media Use Study","SMUS","Inclusion Criteria:\n\n* The participant is 18 or older.\n* The participant must be a Johns Hopkins University student.\n* Owning an iPhone or Android smartphone, with frequent use of social media use daily (\\>\n\n  1 hour)\n* Enabling and sharing screenshots of the participant's smartphone use metrics, including number of last-week pickups, notifications received, and average screen time.\n* Providing consent to participate.\n* Only exercising 1 hour or less daily, on average.\n\nExclusion Criteria:\n\n* younger than 18\n* Not a Johns Hopkins University Student\n* Doesn't own a smart phone\n* Uses smartphone less than 1 hour daily\n* Exercises more than 1 hour daily",{"count":207,"type":22},[25],"The investigators will be randomizing 300 college student participants with high levels of social media use into either a 1) control condition (no intervention), a 2) mindfulness meditation cognitive intervention, or 3) a social media reduction + exercise replacement intervention. Participants complete intervention activities daily for two weeks. The investigators will collect self-report and behavioral measures of social media use and related psychological constructs at three time points: baseline, immediately after the intervention period, and one-week after the intervention period (three weeks from baseline).",[262,31,263,34],"Social Media Addiction","Depression Disorder",[265,266,267,268],"digital media reduction intervention","mindfulness","behavioral intervention","digital wellbeing","2025-12-16",{"date":271,"type":48},"2025-12-17",{"date":273,"type":48},"2025-08-24",{"date":275,"type":22},"2027-01",{"name":277,"class":55},"Johns Hopkins Bloomberg School of Public Health",{"id":279,"slug":280,"hasResults":11,"nctId":281,"briefTitle":282,"officialTitle":283,"acronym":284,"eligibilityCriteria":285,"healthyVolunteers":11,"sex":17,"minAge":286,"maxAge":287,"enrollmentInfo":288,"targetDuration":4,"studyType":23,"phases":290,"briefSummary":291,"conditions":292,"keywords":303,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":318,"locationsCount":56},"100579744","culturally-adapted-i-cbt-for-farsidari-speaking-migrants-100579744","NCT06828276","Culturally Adapted i-CBT for Farsi\u002FDari Speaking Migrants","Culturally and Language-Adapted i-CBT for Common Mental Health Problems: A Randomized Controlled Study With Farsi\u002FDari-Speaking Migrants","i-CBT","Inclusion Criteria:\n\n* Between the ages of 15 and 29.\n* A score above the cut-off 1.75 on HSCL-25\n* Has a refugee or migrant background\n* Has a good and stable internet connection\n* Has access to a computer, tablet or smartphone\n* Is fluent in reading and writing Arabic\n* Has the ability to dedicate time to take part in the intervention for 6-10 weeks.\n\nExclusion Criteria:\n\n* Is suffering from a severe mental illness, such as psychosis or severe depression.\n* Is suffering from substance abuse\n* Is undergoing a psychological treatment\n* Has a high risk of suicide","15 Years","29 Years",{"count":289,"type":22},128,[25],"The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues among Farsi\u002FDari-speaking youth migrants and refugees. Investigator hypothesizes that there will be a significant decrease in psychological symptoms after participants receive the intervention compared to a control group.",[293,294,295,296,297,298,121,299,300,34,301,302],"Depressive Symptoms","Anxiety Symptoms","Grief","Psychological Trauma","Insomnia","Resilience","Psychological Well Being","Marital Relationship","Common Mental Health Problems","Rumination",[304,305,306,307,308,309,310,298,311],"Refugee","Cognitive behavioral therapy","Psychological problems","Persian speaking","Psychological well-being","Youth","Mental problems","Asylum seeker","2025-12-05",{"date":314,"type":48},"2025-12-12",{"date":316,"type":48},"2025-03-25",{"date":247,"type":22},{"name":319,"class":55},"Karolinska Institutet",{"id":321,"slug":322,"hasResults":11,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":326,"eligibilityCriteria":327,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":328,"targetDuration":4,"studyType":23,"phases":330,"briefSummary":331,"conditions":332,"keywords":335,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":340,"startDateStruct":341,"completionDateStruct":343,"leadSponsor":345,"locationsCount":56},"100566232","the-student-wellness-and-emotional-growth-resiliency-swag-r-program-100566232","NCT06652503","The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program","The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program: A 6-week Coaching Program Designed For NSU Undergraduate Students to Decrease Anxiety, Depression, and Stress and Improve Mental Health, Quality of Life, and Resiliency","SWAG-R","Inclusion Criteria:\n\n* Currently matriculating NSU undergraduate students (ages 18+)\n\nExclusion Criteria:\n\n* Students who are not current NSU undergrads, participants aged 17 and younger, students who are currently enrolled in psychotherapy or mental health services, or students with acute mental health needs (e.g., psychosis, active alcohol or substance use problems, suicidality)",{"count":329,"type":22},160,[25],"The purpose of this research study is to provide a free 6-week, online psychological coaching program to NSU undergraduate students to help with anxiety, depression, and stress, while improving quality of life and healthy coping skills.",[31,333,121,34,334],"Depression","Quality of Life",[336,337,338,183,339],"anxiety","depression","stress","quality of life",{"date":314,"type":48},{"date":342,"type":48},"2025-01-13",{"date":344,"type":22},"2026-09",{"name":346,"class":55},"Nova Southeastern University",{"id":348,"slug":349,"hasResults":11,"nctId":350,"briefTitle":351,"officialTitle":352,"acronym":4,"eligibilityCriteria":353,"healthyVolunteers":88,"sex":17,"minAge":354,"maxAge":4,"enrollmentInfo":355,"targetDuration":4,"studyType":23,"phases":357,"briefSummary":359,"conditions":360,"keywords":362,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":369,"lastUpdatePostDateStruct":370,"startDateStruct":372,"completionDateStruct":374,"leadSponsor":376,"locationsCount":56},"100610077","phase-2-impact-of-smell-testing-on-health-outcomes-100610077","NCT07222891","Impact of Smell Testing on Health Outcomes","Validating the Impact of Smell Testing on Health Outcomes and Provider Engagement.","Inclusion Criteria:\n\n\\- Can read and understand English and have access to a reliable internet connection and a smart device or computer for the duration of the experimental sessions, unless they are part of community events in which smart devices are provided\n\nExclusion Criteria:\n\n\\- Known intolerance or allergy to any of the odor stimuli used","7 Years",{"count":356,"type":22},1000,[358],"PHASE2","Smell dysfunction is frequent yet neglected. The sense of smell plays a crucial role in signaling disease, safety, and overall quality of life. However, the significance of a functional sense of smell in terms of health and well-being is often overlooked until one experiences a loss of smell due to injury or disease. Research demonstrates that individuals are often not self-aware of their smell dysfunction (i.e. they do not spontaneously report smell dysfunction as a symptom), especially if the changes are gradual, as in normal aging. Patients with smell dysfunction experience a marked reduction in quality of life, poor mental health, nutritional health, and brain health as well as increased 5- and 10-year mortality in older adults. This study explores whether or not enabling healthcare providers to offer resources and guidance on coping strategies for smell dysfunction improves health and wellbeing in those who experience it.",[361,34],"Olfactory Dysfunction",[363,364,365,366,367,368],"Olfactory testing","Smell dysfunction","Psychological health","Randomized clinical trial","Patient-centered care","Access to care","2025-10-29",{"date":371,"type":48},"2025-10-30",{"date":373,"type":22},"2025-11-01",{"date":375,"type":22},"2027-11-30",{"name":377,"class":55},"Monell Chemical Senses Center",{"id":379,"slug":380,"hasResults":11,"nctId":381,"briefTitle":382,"officialTitle":383,"acronym":384,"eligibilityCriteria":385,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":386,"targetDuration":4,"studyType":23,"phases":388,"briefSummary":389,"conditions":390,"keywords":393,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":396,"lastUpdatePostDateStruct":397,"startDateStruct":399,"completionDateStruct":401,"leadSponsor":403,"locationsCount":56},"100601327","virtual-reality-within-palliative-care-vr-spc-100601327","NCT07109050","Virtual Reality Within Palliative Care (VR-SPC)","The Effectiveness of Virtual Reality Interventions Within Specialist Palliative Care (VR-SPC): A Hermeneutic Single Case Efficacy Design (HSCED) Series","VR-SPC","Inclusion criteria:\n\nParticipants recieving palliative care must be:\n\n* Aged 18 or over (no upper age limit due to the service being lifelong).\n* Patients deemed to be palliative, receiving specialist care at the designated hospice as either an inpatient or outpatient.\n* Willing and able to engage in VR interventions as determined by the patients' usual care team.\n* Able to consent to the research, as assessed by the clinical psychologist supporting recruitment and the primary researcher delivering the VR intervention.\n\nParticipant companions (carers, relatives) must be:\n\n* Aged 18 or over (no upper age limit).\n* Willing and able to engage in VR interventions and travel to the designated hospice site.\n* Able to consent to the research, as assessed by the clinical psychologist supporting recruitment and the primary researcher delivering the VR intervention.\n\nExclusion criteria:\n\n* Lacking capacity to consent to take part in research as assessed by both the clinical psychologist supporting recruitment and the primary researcher delivering VR.\n* Exhibiting contraindications as set out by care team including eyesight impairments or neurological conditions such as epilepsy or dementia.",{"count":387,"type":22},12,[25],"Literature so far shows VR is largely acceptable and feasible to use in palliative care settings, especially for improving patient wellbeing and mental health. However, limited research exists for understanding the effectiveness of VR, especially if sessions are repeated or offered jointly with patient carers or companions. We aim to investigate the effectiveness of VR for achieving personally meaningful goals (including but not limited to relaxation, bucket-list activities, and improving wellbeing). This study will be offered to patients and their companions receiving palliative care at a hospice in England. Informed consent will be acquired after a participant information sheet has been shared with interested participants. Personal goals of VR use will be established at the start of the study with baseline mental health and wellbeing data collection. Up to 3 VR sessions will be offered.\n\nBefore and after each session patients will be asked to complete questionnaires to track wellbeing and progression towards intended goals for utilising VR. A change interview will occur between 1 to 4 weeks after the final VR session to discuss their overall experiences of VR and will include repeated follow up questionnaires. Participants that which to engage with a joint-VR intervention with their companion (referred to as participant companions for the purposes of this study), will also require informed consent and completion of questionnaires and interview attendance to be involved with this study.\n\nResults will be gathered and analysed by creating anonymous individual rich case records and shared with a panel of independent psychologists to conclude whether or not, from our findings, virtual reality is effective for achieving personally important goals. Findings will be shared with the hospice involved and form a Doctoral Thesis based at the University of Lincoln.",[391,392,34],"Palliative Care","Virtual Reality",[394,395],"virtual reality","palliative care","2025-09-08",{"date":398,"type":48},"2025-09-15",{"date":400,"type":48},"2025-08-13",{"date":402,"type":22},"2026-02-28",{"name":404,"class":55},"University of Lincoln",{"id":406,"slug":407,"hasResults":11,"nctId":408,"briefTitle":409,"officialTitle":409,"acronym":4,"eligibilityCriteria":410,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":411,"targetDuration":413,"studyType":208,"phases":4,"briefSummary":414,"conditions":415,"keywords":425,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":431,"lastUpdatePostDateStruct":432,"startDateStruct":434,"completionDateStruct":436,"leadSponsor":438,"locationsCount":198},"100589754","apple-health-study-100589754","NCT06958523","Apple Health Study","Inclusion Criteria:\n\n* Be at least 18 years old (at least 19 years old in Alabama and Nebraska, at least 21 years old in Puerto Rico);\n* Live in the United States of America;\n* Have an iPhone;\n* Have installed Apple Research app on your iPhone;\n* Be comfortable communicating in written and spoken English;\n* Be willing and able to provide informed consent to participate in the Study.\n\nExclusion Criteria:\n\n* Share your iCloud account, iPhone, or devices that collect health data such as Apple Watch with anyone else, because it could result in sharing another person's health information with the Study, making it challenging for researchers to use your information.",{"count":412,"type":22},500000,"5 Years","The Apple Health Study aims to build a diverse and inclusive group of participants to help researchers advance our understanding of how signals and information collected from apps and devices relate to health and may be used to predict, detect, monitor, and manage changes in health.\n\nTo enroll, US residents who have an iPhone can download the Apple Research app from the App Store and go through the introduction and informed consent for the Apple Health Study. This study is fully remote, and all are invited to enroll if the eligibility criteria are met.\n\nParticipants will be asked to complete tasks and surveys, using their iPhone and Apple Research app which include:\n\n* Selecting the types of data they would like to share with the study such as health and sensor data\n* Completing tasks and surveys including areas such as personal demographic information, personal medical history, family history, and social determinants of health",[119,211,416,417,418,419,173,420,421,422,423,34,424],"Exercise","Hormones","Metabolic Health","Hearing","Lifestyle Factors","Functional Capacity","Neurological Conditions","General Health","Women's Health",[409,426,427,428,429,430],"Large Scale Digital Study","Digital Biomarkers","Research App","Apple Research App","iPhone","2025-07-24",{"date":433,"type":48},"2025-07-29",{"date":435,"type":48},"2025-02-12",{"date":437,"type":22},"2030-02",{"name":439,"class":440},"Apple Inc.","INDUSTRY",{"id":442,"slug":443,"hasResults":11,"nctId":444,"briefTitle":445,"officialTitle":446,"acronym":447,"eligibilityCriteria":448,"healthyVolunteers":88,"sex":89,"minAge":64,"maxAge":4,"enrollmentInfo":449,"targetDuration":4,"studyType":23,"phases":451,"briefSummary":452,"conditions":453,"keywords":458,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":465,"lastUpdatePostDateStruct":466,"startDateStruct":468,"completionDateStruct":470,"leadSponsor":472,"locationsCount":56},"100583059","effectiveness-of-an-online-biopsychosocial-intervention-to-improve-well-being-and-mental-health-during-pregnancy-100583059","NCT06871397","Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy","Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy: A Randomized Clinical Trial","BienGestar","Inclusion Criteria:\n\n* Pregnant women\n* Pregnancy of less than 15 weeks of gestation\n* More than 18 years old age\n* Able to read, write, and understand Spanish\n* In possession of a smartphone\n* Able to manage smartphone apps\n* Have signed a written informed consent document\n\nExclusion Criteria:\n\n* Having a high-risk pregnancy that entails transfer to another specialized health centre\n* Having diagnosis of disease that may affect the central nervous system, such as brain pathology or traumatic brain injury\n* Having other psychiatric diagnosis or acute psychiatric illness, such as substance dependence or abuse, a presence of schizophrenia or other psychotic disorders or risk for suicide\n* To be under psychopharmacological medication or under psychopharmacological treatment.",{"count":450,"type":22},228,[25],"This study aims to develop and implement a preventive intervention through a mobile application to help pregnant women feel better emotionally and cope with the changes of pregnancy in a more positive way. The idea is to offer practical and accessible tools that allow them to better manage stress, emotions and preparation for motherhood. The intervention proposed in this study is based on psychological strategies that have proven to be effective, such as relaxation exercises, techniques to manage stress and strategies to improve mood, strengthen the relationship with the partner and foster the bond with the baby before its birth.\n\nThe application is designed to accompany pregnant women from the beginning of pregnancy to the postpartum period. It has different programs that include weekly activities on various important topics, such as physical health care, emotional management, connection with the baby during pregnancy, preparation for childbirth and the first months of the newborn's life.\n\nTo evaluate the effectiveness of this tool, a study will be carried out with pregnant women treated by the Catalan Health Service. Participants will be randomly assigned to one of two study groups: the experimental group (in which participants, in addition to the usual medical care offered during pregnancy, will have access to the programs and activities of the app organized in a weekly plan of 5 activities and will have to answer the study questionnaires at weeks 16 and 36 of pregnancy and postpartum) or the control group (in which participants will receive the usual medical care offered during pregnancy, but will not have access to the programs and activities of the app and will have to answer the study questionnaires at weeks 16 and 36 of pregnancy and postpartum).\n\nWomen who use the app are expected to experience greater emotional well-being and a lower risk of developing mental health problems during pregnancy. In addition, they may feel more prepared for motherhood, take better care of their health, have a more positive birth experience and a lower risk of postpartum depression. These women are also expected to develop a stronger bond with their baby and adapt better to the new stage of motherhood.",[454,455,34,456,457],"Prenatal Anxiety","Prenatal Depression","Obstetrical Complications","Postnatal Depression",[183,336,337,459,460,461,462,463,464],"eHealth","maternal mental health","health promotion","cognitive behavioral intervention","randomized controlled trial","pregnancy","2025-07-14",{"date":467,"type":48},"2025-07-17",{"date":469,"type":48},"2025-04-03",{"date":471,"type":22},"2026-09-30",{"name":473,"class":55},"University Rovira i Virgili",{"id":475,"slug":476,"hasResults":11,"nctId":477,"briefTitle":478,"officialTitle":479,"acronym":4,"eligibilityCriteria":480,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":481,"enrollmentInfo":482,"targetDuration":4,"studyType":23,"phases":484,"briefSummary":485,"conditions":486,"keywords":490,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":492,"lastUpdatePostDateStruct":493,"startDateStruct":495,"completionDateStruct":497,"leadSponsor":499,"locationsCount":56},"100576091","investigating-the-acute-and-chronic-effects-of-a-supplement-containing-caffeine-vitamins-minerals-and-botanical-extracts-on-cognition-sleep-and-wellbeing-in-healthy-volunteers-100576091","NCT06780774","Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers","Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers.","Inclusion Criteria:\n\n* You self-assess yourself as being in good health.\n* You are aged 18-75 years at the time of giving consent.\n* English is your first language or are fluent in English.\n\nExclusion Criteria:\n\n* Insufficient (\\\u003C 40 mg per day) or excessive (\\> 500 mg per day) habitual caffeine consumption (\\* NOTE: This will be calculated at screening but feel free to query this with the researcher prior to attendance.).\n* Have any pre-existing medical conditions\u002Fillnesses which will impact taking part in the study. (\\* NOTE: The explicit exceptions to this are controlled hyper\u002Fhypothyroidism, hay fever, high cholesterol and reflux-related conditions. NOTE: There may be other, unforeseen, exceptions and these will be considered on a case-by-case basis, i.e. participants may be allowed to progress to screening if they have a condition\u002Fillness which would not interact with the active treatments or impede performance so it's worth discussing any medical conditions with the researcher prior to booking lab appointments).\n* Are currently taking prescription medications which will impact taking part in the study (\\* NOTE: the explicit exceptions to this are contraceptive treatments for female participants, thyroid medications, topical skin treatments and those medications used in the treatment of high cholesterol and reflux-related conditions; and those taken 'as needed' in the treatment of asthma and hay fever.).\n* Have high blood pressure (systolic over 139 mm Hg or diastolic over 89 mm Hg1) - \\*NOTE: We must measure this in the lab using our blood pressure monitors and can only use our measurements to access eligibility rather than home or GP readings.\n* Have a Body Mass Index (BMI) outside of the range 18.5-39.9 kg\u002Fm2.\n* Are pregnant, seeking to become pregnant or lactating.\n* Have been diagnosed with a neurological condition or assessed as having a learning\u002Fbehavioural or neurodevelopmental difference (e.g. dyslexia, autism, ADHD).\n* Have a visual impairment that cannot be corrected with glasses or contact lenses (including colour-blindness).\n* Smoke tobacco\u002F vape nicotine\u002F use nicotine replacement products (\\* NOTE: If participants have recently quit smoking or using replacements, they must have stopped using them altogether for a period of 3 months before participating in this study).\n* Have relevant food allergies\u002F intolerances\u002F sensitivities (Please discuss all allergies\u002F intolerances\u002F sensitivities with the researcher prior to your screening appointment).\n* Have taken antibiotics within the past 4 weeks.\n* Are currently consuming any other dietary supplement (e.g., vitamins, omega 3 fish oils etc.) or have done so in the last 4 weeks. (\\* NOTE: Participation is possible following a 4-week supplement wash out prior to participating and for the duration of the study on the proviso that the supplements they are taking are out of choice and not medically prescribed or advised. Please discuss with the researcher if unsure. NOTE: We would never advise stopping supplements prescribed by your doctor e.g., iron, calcium etc., only those you use out of choice).\n* Have any health conditions that would prevent the fulfilment of the study requirements (this includes non-diagnosed conditions for which no medication may be taken).\n* Are unable to complete all of the study assessments (this will be assessed by the researcher at your training appointment, whereby you must be able to reach the minimum scores for each cognitive task to progress with the trial).\n* Are currently participating in another clinical or nutrition intervention study or have done so in the past 4 weeks.\n* Have been diagnosed with\u002F undergoing treatment for alcohol or drug abuse in the last 12 months.\n* Have been diagnosed with\u002F undergoing treatment for a psychiatric disorder in the last 12 months, including a medical diagnosis of anxiety or depression.\n* Suffer from frequent migraines that require medication (more than or equal to 1 per month).\n* Have any sleep disorders or take any sleep aid medications.\n* Have any known active infections.\n* Will be non-compliant with regards to treatment consumption.\n* Does not have a bank account (required for payment).","75 Years",{"count":483,"type":22},90,[25],"The aim of the study is to investigate the acute and chronic effects of a supplement containing Caffeine, Vitamins, Minerals and Botanical extracts on cognitive function, sleep and wellbeing, in healthy volunteers.\n\nThe study will follow a randomised, double-blind, placebo-controlled, crossover design. Participants will receive both treatments, and both study arms will include an acute testing visit (day 1) and a chronic testing visit (day 29). The active treatment contains a blend of 120mg caffeine, vitamins, minerals and botanical extracts and the matched placebo treatment contains marigold extract and brown rice flour.\n\nThe trial will use computerised cognitive tasks, administered via COMPASS software (Northumbria University, UK), online cognitive assessments via Cognimapp and self-reported questionnaires and sleep diary, as measures of the outcome variables.\n\n90 participants will participate, aged 18-75, and self-ported as being in good health. Participants will be randomly allocated to a treatment order and will be supplied with either the active treatment or the placebo whilst visiting the research centre for the acute testing visits. Participants will take the treatment home to consume daily for the duration of the supplementation period. Participants will record the time of taking treatment each day in a treatment diary which will be returned to the research centre, along with any unused treatment, at each chronic testing visit.",[487,211,488,34,489],"Caffeine","Cognitive Function","Mood",[487,491,211,34,489],"Cognitive function","2025-02-06",{"date":494,"type":48},"2025-02-10",{"date":496,"type":22},"2025-02-24",{"date":498,"type":22},"2025-12-19",{"name":500,"class":55},"Northumbria University",{"id":502,"slug":503,"hasResults":11,"nctId":504,"briefTitle":505,"officialTitle":506,"acronym":507,"eligibilityCriteria":508,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":509,"targetDuration":4,"studyType":23,"phases":511,"briefSummary":512,"conditions":513,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":515,"lastUpdatePostDateStruct":516,"startDateStruct":518,"completionDateStruct":520,"leadSponsor":522,"locationsCount":56},"100413820","effects-of-the-5-ways-to-wellbeing-course-effects-of-the-5-ways-to-wellbeing-course-100413820","NCT04668560","Effects of the 5 Ways to Wellbeing Course Effects of the 5 Ways to Wellbeing Course","Improving Wellbeing, Health and Work Adherence Effects of the 5 Ways to Wellbeing Course","FiveWays","Inclusion Criteria:\n\n* individuals with, or at high risk of disease, who need support in health behaviour change and in coping with health problems and chronic disease.\n* individuals on sick leave, work assessment allowance (AAP) and disability pension\n\nExclusion Criteria:\n\n* Severe mental illhealth\n* impaired cognitive functioning",{"count":510,"type":22},700,[25],"Norway and other Western industrialized countries are facing major challenges in terms of preventable health problems, high work absence, largescale demographic changes and rising social inequalities in health. This project addresses the need for effective means to meet these important challenges. The project will scientifically evaluate The 5 Ways to Wellbeing course (5Ways), a novel measure aiming to promote wellbeing and integration, health and work adherence. Subjective wellbeing is systematically and prospectively related to important individual and societal outcomes, including social connectedness and integration, innovation, productivity, work performance, healthy behaviours, health and longevity. Promotion of wellbeing may therefore contribute to address the urgent societal ailments of today. Intervention effects and cost effectiveness of the 5Ways will be examined in-depth in four real-life settings, using quantitative methods. Specifically, we will investigate course impact wellbeing, health and work adherence among users of The Norwegian Labour and Welfare Administration (NAV) and clients in Healthy Life Centres. If effective, the course may be implemented nationwide and contribute to increase wellbeing and work participation. Findings from the study may thus contribute to enable municipalities and workplaces to make better priorities for promoting work presence, reducing suffering and improving mastery and quality of life among their inhabitants.",[34,334,514],"Mental Health Wellness 1","2025-01-14",{"date":517,"type":48},"2025-01-16",{"date":519,"type":48},"2020-02-01",{"date":521,"type":22},"2025-06-30",{"name":523,"class":524},"Norwegian Institute of Public Health","OTHER_GOV",{"id":526,"slug":527,"hasResults":11,"nctId":528,"briefTitle":529,"officialTitle":529,"acronym":4,"eligibilityCriteria":530,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":4,"enrollmentInfo":531,"targetDuration":4,"studyType":23,"phases":533,"briefSummary":534,"conditions":535,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":539,"startDateStruct":541,"completionDateStruct":543,"leadSponsor":545,"locationsCount":56},"100561875","acceptability-feasibility-and-effectiveness-of-a-four-week-feeling-tone-mindfulness-course-100561875","NCT06595849","Acceptability, Feasibility, and Effectiveness of a Four-Week Feeling Tone Mindfulness Course","Inclusion Criteria:\n\n* aged 18 or above\n* speak and understand Cantonese as well as written Chinese to a level where the participant can fully take part in the course without the need for translation support\n* have means to access online teleconferencing meeting software (e.g., Zoom), online surveys, online intervention materials, and Short Message Service (SMS) or WhatsApp messenger\n\nExclusion Criteria:\n\n* moderately severe or severe depressive or anxiety symptoms\n* diagnosed with bipolar disorder or bipolar affective disorder (type I or type II) or ever experienced a manic\u002Fhypomanic episode\n* diagnosed with schizophrenia\u002F psychosis or ever experienced a psychotic episode\n* diagnosed with dementia\u002F neurocognitive disorders\u002F neurological disorders\n* diagnosed with intellectual disability\n* diagnosed with other neurodevelopmental disorders\n* experience of a traumatic event that is currently affecting the potential participants\n* recent bereavement, major loss, or stressful life events\n* suicidal\n* alcohol or drug abuse\n* currently experiencing other mental or physical health condition, or life condition that might affect potential participants' participation in the course\n* prior experience of taking part in the feeling tone intervention as a course participant",{"count":532,"type":22},80,[25],"This is an academic research study aiming to explore the acceptability, feasibility, and effectiveness of a four-week feeling tone mindfulness course on equanimity, mindfulness, self-compassion, and mental health outcomes.",[536,333,31,121,34,537],"Mindfulness","Self-compassion","2024-09-11",{"date":540,"type":48},"2024-09-19",{"date":542,"type":22},"2024-10",{"date":544,"type":22},"2026-08",{"name":546,"class":55},"The University of Hong Kong",{"id":548,"slug":549,"hasResults":11,"nctId":550,"briefTitle":551,"officialTitle":552,"acronym":553,"eligibilityCriteria":554,"healthyVolunteers":88,"sex":17,"minAge":64,"maxAge":555,"enrollmentInfo":556,"targetDuration":413,"studyType":208,"phases":4,"briefSummary":558,"conditions":559,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":574,"lastUpdatePostDateStruct":575,"startDateStruct":577,"completionDateStruct":579,"leadSponsor":581,"locationsCount":56},"100498046","safe-brain-initiative-operationalizing-precision-anaesthesia-100498046","NCT05765162","Safe Brain Initiative, Operationalizing Precision Anaesthesia","Safe Brain Initiative - Dedicated to Advancing Anaesthesia and Perioperative Personalised Care Towards Precision Anaesthesia Care. A Continuous Quality Improvement Initiative.","SBI","Inclusion Criteria:\n\n• All patients from age ≥18\n\nExclusion Criteria:\n\n• All patients from age \\\u003C18","100 Years",{"count":557,"type":22},15000,"Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress. Moreover, many patients develop postoperative delirium (POD) and neurocognitive dysfunctions, often resulting in long-term cognitive impairment, decreased quality of life, and increased mortality. However, physicians, nurses and their institutions do not receive structured feedback regarding these aspects of each patient's well-being. They may therefore be unable to engage in the essential cause-and-effect learning necessary to evaluate and consecutively reduce such side effects.\n\nEffective guidelines conform prevention is the proven key to shielding our patients from adverse Outcomes. The Safe Brain Initiative's high-quality routine data-for-action is a sword and accelerator for moving towards patient-centred, precision care. Thus, establishing a foundation for value-based and patient-centred healthcare development.\n\nHowever, a turnkey real-world solution is challenging to develop and implement and requires substantial resources. As a result, such solutions are usually beyond the scope of a single institution. The SBI platform provides high-quality, real-world data to bridge this gap. It allows monitoring and in-depth analysis of cause and effect in the day-to-day routine of individuals, departments, and institutions.\n\nThe SBI's approach is continuously improved and updated. An organization called the SBI Global Society oversees the quality and precision of science through experts in the field. At SBI Hospitals and Flagship centres, Masterclasses are conducted and can be attended alongside clinical immersions.\n\nSBI Solutions manages, develops, and provides technical and service support for the Safe Brain Initiative. Its service guarantees the professional and GDPR conform management of data handling and storage as well as the user-friendly functionality of the SBI-Dashboard solutions.",[560,561,562,563,564,34,565,31,121,566,567,568,569,570,571,572,573],"Neurocognitive Disorders","Post Operative Delirium","Pain","Nausea","Vomiting","Shivering","Agitation,Psychomotor","Sedation Complication","Thirst","Satisfaction, Patient","Temperature Change, Body","Fasting","Sore-throat","Hearing and Vision Loss","2024-06-05",{"date":576,"type":48},"2024-06-07",{"date":578,"type":48},"2021-12-01",{"date":580,"type":22},"2026-01-01",{"name":582,"class":55},"University of Southern Denmark",{"id":584,"slug":585,"hasResults":11,"nctId":586,"briefTitle":587,"officialTitle":588,"acronym":589,"eligibilityCriteria":590,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":591,"targetDuration":4,"studyType":23,"phases":593,"briefSummary":594,"conditions":595,"keywords":597,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":605,"lastUpdatePostDateStruct":606,"startDateStruct":608,"completionDateStruct":610,"leadSponsor":612,"locationsCount":56},"100550701","on-line-evidence-based-positive-parenting-program-for-families-with-adolescents-exhibiting-mental-health-problems-100550701","NCT06450496","On-line Evidence-based Positive Parenting Program for Families With Adolescents Exhibiting Mental Health Problems","Development of an On-line Evidence-based Positive Parenting Program for Families With Adolescents Exhibiting Mental Health Problems (Bienestar)","Bienestar","The participants will be the caregivers (mothers or fathers) of adolescents with mental health problems of Spain. The caregiver and the target adolescent will act as respondents.\n\nFor the caregivers, the inclusion criteria are:\n\n* Relationship with the identified patient (adolescent): Mother or father who fulfils the role of caregiver.\n* They have some computer support (PC, tablet, mobile phone...) with which to carry out the program.\n* Time availability to participate in the evaluation sessions.\n* Motivation to participate in the program.\n\nFor the adolescents, the inclusion criteria are:\n\n* Age between 10 and 19 years old.\n* Experiencing any mental health problem.\n\nAll the inclusion criteria are requested to participate in the study.\n\nExclusion criteria:\n\nCaregivers:\n\n* Do not have an A2 Spanish language level.\n* Show signs of addiction to toxic substances.\n\nTarget adolescents:\n\n* Age less than 10 years or more than 19 years.\n* Do not have an A2 Spanish language leve.\n\nAny exclusion criteria will be considering for exclusion.",{"count":592,"type":22},158,[25],"This project proposes the design, implementation, and evaluation of an online psycho-educational intervention program for families of adolescents with mental health problems.",[596,34],"Parenting",[598,599,600,601,119,602,603,604],"Effectiveness","Positive Parenting","Families","Adolescents","On-line Intervention","Evidence-based program","Random-control trial","2024-06-03",{"date":607,"type":48},"2024-06-10",{"date":609,"type":22},"2024-06",{"date":611,"type":22},"2025-01",{"name":613,"class":55},"Lucia Jimenez"]