[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"woman-of-reproductive-age\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:woman-of-reproductive-age":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100595794","understanding-cycles-to-improve-womens-health-100595794",false,"NCT07037082","Understanding Cycles to Improve Women's Health","Understanding Socio-ecological Variation in Menstrual Cycles to Advance Female Health","C-HEALTH","Inclusion Criteria:\n\n* Woman of childbearing age (18-39 years)\n* Woman not using hormonal contraception for at least 6 months\n* Woman with semi-regular menstrual cycles between 21 and 45 days inclusive\n* Woman with no known history of infertility\n* Woman working in the same environment (urban\u002Frural) as her place of residence\n* Knowledge of the dates of periods over the last 3 cycles\n* Woman who has a freezer at -20°C\n\nExclusion Criteria:\n\n* Diagnosis by a physician of one or more of the following comorbidities: Polycystic ovarian syndrome (PCOS), Endometriosis, Adenomyosis, Diabetes or thyroid disease, Hormone-dependent gynecological cancers (breast, endometrium, ovaries), Coagulation diseases (von Willebrand), Chronic liver failure, chronic renal failure, heart disease, autoimmune disease, Autism, Diagnosis and\u002For treatment for a psychiatric illness\n* Chronic exposure to cocaine, amphetamine\u002Fmethamphetamine, morphine or ecstasy within 30 days prior to inclusion\n* Chronic exposure to THC within 7 days prior to inclusion.\n* Person who is not comfortable with self-sampling (hematophobia or other)\n* No access to a smartphone\n* No possibility of wearing a connected ring for at least 60 days 22h\u002F24h\n* Pregnant or breastfeeding woman\n* Woman who gave birth or breastfed in the 2 months before the study\n* Person who moved less than 2 years before the study (does not concern participants who moved in the same environment (rural or urban, less than 20 km)\n* Person unable to read French\n* Failure to obtain informed consent\n* Person not benefiting from a national health insurance scheme\n* Person under legal protection, guardianship or curatorship\n* Person participating in other research involving the human person",true,"FEMALE","18 Years","39 Years",{"count":22,"type":23},320,"ESTIMATED","OBSERVATIONAL","Introduction:\n\nThe C-HEALTH study investigates how environmental and socio-economic conditions affect women's menstrual cycles and reproductive health.\n\nAim:\n\nTo compare progesterone levels during the luteal phase among women from different socio-economic backgrounds living in rural and urban areas in southern France.\n\nMethods:\n\nThis is a prospective observational study involving 320 healthy women of reproductive age.\n\n* Hormones (progesterone, estradiol) will be measured daily in saliva.\n* Inflammation (Protéine C Réactive: CRP) will be measured five times per cycle via blood drops.\n* Participants will wear a smart ring to monitor body temperature and activity.\n* Daily symptoms and lifestyle data will be collected.\n* Environmental exposures (pollution, stress, living conditions) will be assessed and linked to menstrual health outcomes.",[27,28],"Woman of Reproductive Age","Socioeconomic Factors",[30,31,32,33,34,35,36,37],"Menstrual Cycle","Exposome","Hormones","Inflammation","Rural\u002FUrban","Socioeconomic status","Pollution","Ovulation","RECRUITING","2026-06-17",{"date":41,"type":42},"2026-06-22","ACTUAL",{"date":44,"type":42},"2025-09-01",{"date":46,"type":23},"2029-07-01",{"name":48,"class":49},"University Hospital, Montpellier","OTHER"]