[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"work-related-stress\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:work-related-stress":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,56,83,126,149,186,233,260,291,318,348,371],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100644136","working-in-the-heat-at-simulated-altitude-effects-of-normobaric-hypoxia-on-physiological-strain-100644136",false,"NCT07664462","Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain","Effects of Normobaric Hypoxia on Initial Stay Time and Physiological Strain During Moderate-Intensity Work in the Heat in Young and Older Males","Inclusion Criteria:\n\n* Are male.\n* Do not smoke or have been smoke free for at least 5 years.\n* English or French speaking.\n* Ability to provide informed consent.\n* Are physically active (engage in exercise at least 2 times per week for ≥30 minutes)\n\nExclusion Criteria:\n\n* Are regularly exposed to hot environments (e.g., occupational heat exposure)\n* Are regularly exposed to hypoxic environments (e.g., high altitudes)\n* Experience claustrophobia or discomfort in enclosed environments\n* Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness).\n* Serious complications related to diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy).\n* Uncontrolled hypertension - BP \\>150 mmHg systolic or \\>95 mmHg diastolic in a sitting position.\n* Restrictions in physical activity due to disease (e.g. intermittent claudication, renal impairment, active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis, etc.).\n* Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable.\n* Cardiac abnormalities identified during screening","MALE","18 Years","70 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers performing physically demanding work in hot environments. Current occupational heat-stress guidelines aim to limit excessive increases in core body temperature and physiological strain through the use of work-rest schedules. However, these guidelines do not provide clear direction on the safe, maximum duration of continuous work that can be performed before heat-mitigation controls should be implemented, known as the initial stay time. Recent work has generated initial stay time recommendations for young and older workers performing moderate-intensity work in the heat, but these estimates were developed under normoxic conditions. In many occupational settings, workers may be exposed to additional environmental stressors such as hypoxia, including work at altitude or in oxygen-reduced environments. Hypoxia can increase cardiovascular strain, reduce arterial oxygen saturation, and alter exercise tolerance, potentially compromising the effectiveness of heat-stress guidance developed under normal oxygen conditions. Older workers may be especially vulnerable due to age-related reductions in thermoregulatory and cardiovascular function. To date, it remains unclear whether hypoxia alters physiological strain during work in the heat or whether current initial stay time and recovery recommendations remain protective under combined heat and hypoxic stress.\n\nThe primary objective of this study is to determine whether exposure to hypoxia increases physiological strain during moderate-intensity work in the heat in young and older males. Specifically, investigators will assess whether normoxia-derived initial stay times and recovery recommendations for work at 29°C wet-bulb globe (37.5°C, 35% RH) temperature remain effective when workers are exposed to hypoxia equivalent to 14% inspired oxygen (simulating \\~3000 m in altitude). Healthy young and older males will complete simulated occupational heat exposure under two conditions: heat alone and combined heat plus hypoxia. Participants will perform moderate-intensity treadmill work based on age-specific initial stay times, followed by prescribed work-rest cycles and seated recovery. Measures of core temperature, cardiovascular strain, oxygen saturation, skin temperature, hydration status, perceptual responses, mood, symptoms of environmental stress, and cognitive function will be assessed to determine whether hypoxia modifies responses to work in the heat. This study will provide important evidence on whether occupational heat-stress guidance requires refinement when workers are exposed to combined heat and hypoxic stress.",[27,28,29,30,31,32,33],"Body Temperature Changes","Heat Stress","Heat Exposure","Heat Fatigue","Hypoxia, Altitude","Work Related Stress","Physiological Stress",[35,36,37,38,39,40,41,42,43],"Heat Strain","Thermoregulation","Exercise","Simulated altitude","Core temperature","Occupational Heat Stress","Aging","Hypoxia","Hyperthermia","RECRUITING","2026-06-17",{"date":47,"type":48},"2026-06-24","ACTUAL",{"date":45,"type":21},{"date":51,"type":21},"2027-02-28",{"name":53,"class":54},"University of Ottawa","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":16,"minAge":64,"maxAge":18,"enrollmentInfo":65,"targetDuration":4,"studyType":22,"phases":67,"briefSummary":68,"conditions":69,"keywords":70,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":55},"100641555","consecutive-occupational-heat-exposure-with-and-without-overnight-cooling-100641555","NCT07656519","Consecutive Occupational Heat Exposure With and Without Overnight Cooling","Physiological Responses to Consecutive Days of Occupational Heat Exposure With and Without Overnight Access to Cooling","Inclusion Criteria:\n\n* Are male.\n* Do not smoke or have been smoke free for at least 5 years.\n* English or French speaking.\n* Ability to provide informed consent.\n* Are physically active (engage in exercise at least 2 times per week for ≥30 minutes)\n\nExclusion Criteria:\n\n* Are regularly exposed to hot environments (e.g., occupational heat exposure)\n* Experience claustrophobia or discomfort in enclosed environments\n* Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness).\n* Serious complications related to diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy).\n* Uncontrolled hypertension - BP \\>150 mmHg systolic or \\>95 mmHg diastolic in a sitting position.\n* Restrictions in physical activity due to disease (e.g. intermittent claudication, renal impairment, active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis, etc.).\n* Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable.\n* Cardiac abnormalities identified during screening",true,"50 Years",{"count":66,"type":21},10,[24],"Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers exposed to hot environments. Current occupational heat-stress guidelines are designed to limit excessive increases in core body temperature and physiological strain during work in the heat through the use of work-rest schedules. However, these guidelines are largely based on single-day heat exposures and assume that workers recover in cool indoor environments between shifts. During heat events, many workers may instead recover in homes or accommodations that remain overheated, particularly in the absence of air conditioning. Inadequate overnight cooling may impair the body's ability to dissipate heat, increase physiological strain, and reduce tolerance to heat exposure on subsequent workdays. Older adults may be especially vulnerable due to age-related impairments in heat-loss capacity. To date, the effects of recovering in an overheated indoor environment on physiological strain and thermoregulatory function during repeated occupational heat exposure remain poorly understood, limiting the development of evidence-based recommendations to protect workers during prolonged heat events.\n\nThe primary objective of this study is to determine whether overnight recovery in an overheated indoor environment increases physiological strain during repeated occupational heat exposure in older adults. Specifically, investigators will assess whether recovery at the recently proposed upper indoor temperature limit of 26°C and 45% relative humidity (RH) (PMID: 38329752) is sufficient to attenuate elevations in core temperature during subsequent work in the heat compared with recovery in an overheated indoor environment (31°C, 45% RH) representative of conditions commonly experienced during extreme heat events. Healthy older adults will complete two consecutive days and nights of simulated moderate-intensity occupational heat exposure, with overnight recovery occurring in either the 26°C or 31°C condition. Measures of core temperature, cardiovascular strain, heat-loss capacity, hydration status, sleep quality, cognitive function, mood, and perceptual responses will be assessed to determine the impact of overnight recovery conditions on responses to repeated heat exposure. Whole-body heat-loss capacity will also be evaluated before and after the exposure protocol as assessed during incremental, intermittent exercise protocol performed in an air calorimeter.",[27,28,29,30,32,33],[35,36,37,39,71,41,72,73,43],"Occupational heat stress","Heat wave","Sleep","NOT_YET_RECRUITING","2026-06-14",{"date":77,"type":48},"2026-06-18",{"date":79,"type":21},"2026-07-01",{"date":81,"type":21},"2027-08-31",{"name":53,"class":54},{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":63,"sex":91,"minAge":17,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":103,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":125},"100634808","xr2esilience---xr-based-resilience-training-for-stress-and-mental-health-in-healthcare-workers-100634808","NCT07544498","XR2ESILIENCE - XR-Based Resilience Training for Stress and Mental Health in Healthcare Workers","A Pragmatic Randomized Controlled Trial Study Protocol: XR2ESILIENCE - Pioneering XR Technology for the Promotion of Resilience and Mental Health of the Healthcare Workforce","XR2ESILIENCE","Inclusion Criteria:\n\n1. working as a nurse in direct patient care within a clinical setting;\n2. working at least 10h\u002Fweek in their profession;\n3. speaking the language in which the RCT is conducted sufficiently well;\n4. able and willing to participate in all aspects of the study;\n5. understanding and signing the appropriate informed consent form.\n\nExclusion Criteria:\n\n1. a diagnosed severe mental disorder associated with alterations in reality perception (e.g., delusions, hallucinations, derealization, depersonalization, or dementia), including in particular schizophrenia, bipolar disorder, severe major depressive disorder, or other psychotic disorders (lifetime);\n2. a current major depressive episode or a current post-traumatic stress disorder (PTSD);\n3. an acute or clinically significant medical condition that may interfere with the safe use of an XR headset or study participation, including but not limited to epilepsy, pronounced dizziness, balance disorders, or acute cardiovascular conditions;\n4. an acute eye infection (e.g., conjunctivitis);\n5. unstable medication related to a mental health condition, defined as recent changes in dosage or class of psychotropic medication;\n6. initiation of psychotherapy or any structured stress-management training within the past three months.","ALL","65 Years",{"count":94,"type":21},232,[24],"This study investigates the effectiveness of an extended reality (XR) based resilience training program designed to support the mental health and well-being of nurses working in hospital settings. Nurses are exposed to high emotional, cognitive, and organizational demands and show elevated levels of work-related stress and stress-associated mental health problems. Strengthening resilience and coping capacities is therefore an important preventive approach to support nurses' well-being and sustain quality of care.\n\nThe study is conducted as a pragmatic randomized controlled trial with a waitlist control group and includes approximately 232 nurses from hospitals in several European countries. Participants are randomly assigned either to an XR-based resilience training group or to a waitlist control group that continues with care as usual during the waiting period. The XR-based intervention consists of eight immersive training sessions delivered over approximately ten weeks using a head-mounted display. The training focuses on behavioral, cognitive, and emotional coping strategies and aims to enhance key resilience factors such as problem-solving, cognitive reappraisal, emotion regulation, and positive self-care.\n\nThe primary outcome is perceived stress, assessed using the Perceived Stress Scale. Secondary outcomes include resilience, occupational self-efficacy, quality of life, psychological distress, burnout symptoms, coping strategies, work-related rumination, and turnover intentions. Assessments are conducted at baseline, post-intervention, and at a 20-week follow-up. In addition, a subgroup of participants will optionally provide physiological data during selected XR sessions to explore digital biomarkers related to stress and recovery.\n\nThe findings of this study will provide evidence on the effectiveness, feasibility, and acceptance of XR-based resilience training for nurses and inform future implementation of digital mental health interventions in healthcare workplaces.",[98,99,100,101,102],"Occupational Stress","Work-Related Stress","Mental Health","Burnout","Resilience",[104,105,106,107,108,109,110,111,112,113,114,115],"Extended Reality","Virtual Reality","XR-based Intervention","Resilience Training","Stress Reduction","Nurses","Healthcare Workers","Occupational Health","Mental Well-Being","Digital Mental Health","Preventive Intervention","Randomized Controlled Trial","2026-05-13",{"date":118,"type":48},"2026-05-18",{"date":120,"type":21},"2026-09",{"date":122,"type":21},"2028-03",{"name":124,"class":54},"Medical University of Graz",8,{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":63,"sex":91,"minAge":17,"maxAge":17,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":55},"100634541","a-mindfulness-based-intervention-for-hotel-staff-100634541","NCT07541027","A Mindfulness-based Intervention for Hotel Staff","Mindfulness Training for Hotel Staff: A Mixed-Methods Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 years or above\n* Currently working in a hotel\n* Cantonese speaker\n* Willing to commit time for the 6-week mindfulness course\n\nExclusion Criteria:\n\n* Individuals who had previously joined a related group mindfulness-based intervention, such as mindfulness-based cognitive therapy (MBCT), mindfulness-based stress reduction (MBSR), or Mindfulness - Finding Peace in a Frantic World (FPFW)\n* Staff members who are mentally unstable or having active suicidal risk",{"count":134,"type":21},60,[24],"This research aims to investigate the potential impact of a structured mindfulness-based professional development program on hotel employees and to explore why and how these changes occur during and after the mindfulness intervention through a mixed-methods approach. A 6-week mindfulness intervention with 60 hotel staff from a hotel will be implemented in Hong Kong. Both quantitative and qualitative data will be collected to examine changes in job-related outcomes, wellbeing, and state mindfulness and teachers' lived experiences and perspectives associated with this intervention. Data will be analyzed based on convergent parallel mixed-method approach, such as mixed-effects modeling, mediation analysis, and thematic analysis. This study may provide practical implications for developing evidence-based programs to promote wellbeing and service quality among hotel employees.",[138,32,139],"Well-Being (Psychological Flourishing)","Work Performance","2026-04-27",{"date":142,"type":48},"2026-04-30",{"date":144,"type":21},"2026-06-01",{"date":146,"type":21},"2027-05-31",{"name":148,"class":54},"Chinese University of Hong Kong",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":63,"sex":91,"minAge":156,"maxAge":92,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":159,"briefSummary":160,"conditions":161,"keywords":166,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":4},"100595156","virtual-mindfulness-and-breathing-training-for-stress-burnout-sleep-and-cognition-in-rotating-shift-nurses-100595156","NCT07028788","Virtual Mindfulness and Breathing Training for Stress, Burnout, Sleep, and Cognition in Rotating-Shift Nurses","Effectiveness of Virtual Mindfulness Combined With Brief Structured Breathing Training on Perceived Stress, Burnout, Sleep Quality, and Cognitive Function Among Rotating-Shift Nurses: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age between 20 and 65 years.\n2. Able to understand spoken or written Mandarin or Taiwanese.\n3. Employed full-time for at least 3 months with a signed employment contract.\n4. Has worked rotating shifts (including day, evening, and\u002For night shifts) in the past 3 months.\n5. Willing to participate and sign informed consent.\n6. Registered nurse.\n7. A perceived stress score greater than or equal to 50 based on a standardized scale.\n\nExclusion Criteria:\n\n1. Pregnant or breastfeeding individuals.\n2. History of substance abuse (e.g., tobacco, illicit drugs).\n3. Alcohol consumption ≥350 ml\u002Fweek with alcohol content ≥3.5%.\n4. Diagnosed or suspected autonomic nervous system disorders.\n5. History of severe or unstable cardiovascular disease, cerebrovascular disease, cancer, or end-stage organ failure within the past 6 months.\n6. Current diagnosis of psychiatric disorders (e.g., major depressive disorder, schizophrenia), or use of psychiatric or sleep medications (e.g., antidepressants, sedatives).\n7. Reported discomfort (e.g., dizziness, nausea) when using virtual reality devices.\n8. Engaged in other regular exercise programs, light therapy, or mind-body interventions during the study period.\n9. Participating in other clinical trials simultaneously.","20 Years",{"count":158,"type":21},300,[24],"This randomized controlled trial aims to evaluate the effectiveness of a mobile- and virtual reality-based mindfulness and breathing intervention on stress, burnout, sleep quality, and cognitive function among Rotating-shift nurses. Participants will be randomly assigned to one of four groups: (1) health education control group, (2) mobile-based mindfulness only, (3) mobile-based mindfulness combined with brief structured breathing, and (4) virtual reality-assisted mindfulness combined with brief structured breathing. The intervention will last for 8 weeks, with participants practicing 5 times per week for 10 minutes per session. Primary outcomes include perceived stress, burnout levels, sleep quality, and cognitive function.",[162,99,163,164,165],"Occupational Burnout","Sleep Disturbance","Cognitive Dysfunction","Shift Work Disorder",[167,168,169,170,171,172,173,174,175,176],"breathing training","burnout","cognitive function","mindfulness meditation","mobile health","perceived stress","physiological arousal","rotating-shift nurse","sleep quality","virtual reality","2026-04-07",{"date":179,"type":48},"2026-04-08",{"date":181,"type":21},"2026-07",{"date":183,"type":21},"2027-12",{"name":185,"class":54},"Chang Shih-Chin",{"id":187,"slug":188,"hasResults":11,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":192,"eligibilityCriteria":193,"healthyVolunteers":63,"sex":91,"minAge":194,"maxAge":18,"enrollmentInfo":195,"targetDuration":4,"studyType":22,"phases":197,"briefSummary":198,"conditions":199,"keywords":205,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":232},"100609887","foundational-programs-to-combat-clinician-stress-100609887","NCT07220421","Foundational Programs to Combat Clinician Stress","Evaluate Foundational Wellness Programs to Help Reduce Clinician Burnout and Improve Professional Fulfilment in Health Care Professionals.","FACCTS","Inclusion Criteria:\n\n* 25-70 years of age,\n* UPHS or MGH clinician (physician, APP, CRNP, PA, psychologist),\n* Access to smart phone and internet,\n* Ability to give informed consent,\n* Interested in wearing an Oura ring and being part of a study to evaluate breath and meditation-derived exercises,\n* Willing to do relaxation exercise every day for 4 weeks.\n\nExclusion Criteria:\n\n* Currently maintaining a regular\u002Fdaily mind-body program practice (eg. meditation, yoga or breathing techniques),\n* Atrial fibrillation,\n* Pacemaker\u002Fdefibrillator,\n* Untreated or severe obstructive sleep apnea (AHI\\>=30),\n* History of diaphragm paralysis,\n* Unable or unwilling to complete the workshop,\n* Severe chronic obstructive pulmonary disease (COPD),\n* Severe valvular heart disease,\n* Prior or planned chest\u002Fabdominal or nasal\u002Ffacial surgery within 6 months,\n* Severe psychiatric illness (e.g. schizophrenia, schizoaffective disorder, bipolar disorder), active substance use, seizure disorder or major somatic illness (uncontrolled hypertension, lung disease, liver disease, cancer or heart disease).","25 Years",{"count":196,"type":21},180,[24],"This is a prospective, randomized, controlled clinical trial in which clinicians from University of Pennsylvania Health Systems (UPHS) including Penn Medicine- Lancaster General Health (LGH) and Massachusetts General Hospital (MGH) are offered a well-known program to help reduce clinician burnout: Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation Intervention.",[200,201,202,203,204,32],"Burnout, Professional","Stress, Psychological","Stress, Physiological","Psychological Well-Being","Mind-Body Therapies",[206,108,207,208,209,210,211,212,213,214,215,73,216,102,217,218,219,220,221,222,162],"Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation","Healthcare Professional Burnout","Workplace Wellbeing","Work Life Balance","Physician","Healthcare Provider","Cognitive Performance","Cognitive Attention","Depression","Anxiety","Heart Rate Variability","Social Connection","Self-Valuation","Professional Fulfilment","Medical Errors","Physician Turnover","Healthcare Economics","2025-10-21",{"date":225,"type":48},"2025-10-23",{"date":227,"type":48},"2025-09-15",{"date":229,"type":21},"2026-05",{"name":231,"class":54},"Lancaster General Hospital",6,{"id":234,"slug":235,"hasResults":11,"nctId":236,"briefTitle":237,"officialTitle":238,"acronym":4,"eligibilityCriteria":239,"healthyVolunteers":11,"sex":91,"minAge":17,"maxAge":92,"enrollmentInfo":240,"targetDuration":4,"studyType":22,"phases":242,"briefSummary":243,"conditions":244,"keywords":245,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":250,"lastUpdatePostDateStruct":251,"startDateStruct":253,"completionDateStruct":255,"leadSponsor":257,"locationsCount":259},"100577523","stop-for-stress---a-randomized-controlled-trial-comparing-an-online-and-a-group-based-format-of-an-intervention-for-work-related-stress-100577523","NCT06799403","Stop for Stress - a Randomized Controlled Trial Comparing an Online and a Group-based Format of an Intervention for Work-related Stress","Stop for Stress - En Sammenligning af Online og Gruppebaseret Behandling for Arbejdsrelateret Stress","Inclusion Criteria:\n\n* Current employment and significant work-related stressors\n* Perceived Stress Scale (PSS-10) score ≥20 and symptom duration \\>4 weeks\n* In case of full-time sick leave, return to work must be planned concurrent with the intervention\n* Access to a computer or tablet with internet connection at home\n\nExclusion Criteria:\n\n* Interpersonal difficulties, bullying, harassment, violence, threats, and traumatic events as primary stressor\n* Severe stressors outside of work\n* Symptoms meeting diagnostic criteria for anxiety, depression or severe psychiatric illnesses requiring specialized treatment\n* Current abuse of alcohol and\u002For psychoactive drugs",{"count":241,"type":21},220,[24],"Work-related stress is a major public health concern, causing sickness absenteeism and impaired health and well-being. Many afflicted with severe work-related stress will not receive evidence-based treatment due to geographical distance, stigma and unwillingness to participate in a group, creating unequality access to healthcare services. Online interventions show comparable effects to face-to-face interventions and have potential to break down some of these barriers. We have developed and pilot tested the online delivery format of the intervention for work-related stress, Stop for Stress, with promising results. In a two-armed, multicentre randomized controlled trial we aim to 1) compare the effect of the online delivery format and an evidence-based face-to-face group-based format and 2) identify markers of enhanced outcomes in each delivery format. The study will include 220 patients with severe work-related stress (110 from each of two centres) who are randomizes 1:1 to the two interventions. Outcomes consist of self-report measures of psychological symptoms, cognitive functioning, sleep, and perceived working environment and register data on ebsenteeism and return-to-work.",[99],[246,247,248,249],"work-related stress","online intervention","group intervention","return-to-work","2025-06-13",{"date":252,"type":48},"2025-06-17",{"date":254,"type":48},"2025-03-27",{"date":256,"type":21},"2027-08",{"name":258,"class":54},"Lea Nørgaard Sørensen",2,{"id":261,"slug":262,"hasResults":11,"nctId":263,"briefTitle":264,"officialTitle":265,"acronym":4,"eligibilityCriteria":266,"healthyVolunteers":63,"sex":91,"minAge":17,"maxAge":267,"enrollmentInfo":268,"targetDuration":4,"studyType":22,"phases":270,"briefSummary":271,"conditions":272,"keywords":275,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":55},"100588714","meta-self-efficacy-internet-intervention-to-improve-work-self-efficacy-and-occupational-well-being-in-young-employees-100588714","NCT06944990","Meta Self-efficacy Internet Intervention to Improve Work Self-efficacy and Occupational Well-being in Young Employees","Meta Self-efficacy Intervention to Improve Work Self-efficacy and Occupational Well-being in Young Employees: Internet Intervention Co-creation and a Randomized Controlled Trial","Inclusion Criteria:\n\n* must be between 18 and 30 years old\n* must be empolyed (working at least 20 h \u002F week, for at least the prior two months, regardless of the type of contract)\n\nExclusion Criteria:\n\n* none","30 Years",{"count":269,"type":21},600,[24],"This randomized controlled trial aims to test whether enhancing meta self-efficacy through a self-guided internet intervention improves young employees' work self-efficacy and occupational well-being. The trial will evaluate primary (work self-efficacy) and secondary (three dimensions of occupational well-being) outcomes. It is hypothesized that boosting meta self-efficacy will lead to improvements in outcomes, with effects assessed immediately after the intervention, and at 3- and 6-month follow-ups.",[273,98,274,32],"Self Efficacy","Well-Being, Psychological",[276,277,278,279,280,281],"meta self-efficacy","self-efficacy","job affective well-being","sustainable employability","work stress","work self-efficacy","2025-04-17",{"date":284,"type":48},"2025-04-25",{"date":286,"type":21},"2026-03-01",{"date":288,"type":21},"2027-12-01",{"name":290,"class":54},"University of Social Sciences and Humanities, Warsaw",{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":4,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":91,"minAge":4,"maxAge":4,"enrollmentInfo":298,"targetDuration":4,"studyType":300,"phases":4,"briefSummary":301,"conditions":302,"keywords":303,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":309,"lastUpdatePostDateStruct":310,"startDateStruct":312,"completionDateStruct":314,"leadSponsor":316,"locationsCount":55},"100518835","patient-acuity-in-somatic-in-patient-care-100518835","NCT06035705","Patient Acuity in Somatic In-patient Care","Patient Acuity Measures as Part of Daily Managment: a Mixed-methods Study Within Somatic In-patient Care","Inclusion Criteria:\n\n* All nurses employed by the medical wards\n* First-line managers at each ward\n\nExclusion Criteria:\n\n* Travelling nurses\n* Nurses with \\\u003C1 months employment",{"count":299,"type":21},250,"OBSERVATIONAL","This study addresses nursing acuity measures within somatic in-patient care. Quantitative and qualitative analyses will be used in order to examine staffing levels and nurses' perception of work environment, before, during and after the implementation of a patient acuity tool as a part of daily management.",[32],[304,305,306,307,308],"nurse staffing","acuity","workload","daily management","job satisfaction","2025-04-09",{"date":311,"type":48},"2025-04-10",{"date":313,"type":48},"2023-09-30",{"date":315,"type":21},"2026-09-30",{"name":317,"class":54},"Region Gävleborg",{"id":319,"slug":320,"hasResults":11,"nctId":321,"briefTitle":322,"officialTitle":323,"acronym":4,"eligibilityCriteria":324,"healthyVolunteers":63,"sex":325,"minAge":17,"maxAge":4,"enrollmentInfo":326,"targetDuration":4,"studyType":22,"phases":328,"briefSummary":329,"conditions":330,"keywords":333,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":339,"lastUpdatePostDateStruct":340,"startDateStruct":342,"completionDateStruct":344,"leadSponsor":346,"locationsCount":55},"100517126","character-strengths-based-coaching-for-work-stress-reduction-for-health-workers-100517126","NCT06013488","Character-Strengths Based Coaching For Work-Stress Reduction For Health Workers","A Character-Strengths Based Coaching Program for Rural Community Health Workers to Address Their Work Stress in India: Protocol for a Two-arm Randomized Controlled Trial","Inclusion Criteria:\n\n* All rural ASHAs residing and working in Sehore district, Madhya Pradesh (verified in the health system records) and who have been trained by the study team on delivering community-based depression care\n\nExclusion Criteria:\n\n* ASHAs who plan to migrate within six months of recruitment\n* ASHAs who do not plan to continue working, or those who have resigned or planning to change jobs within six months of recruitment\n* ASHAs with urban catchment areas\n* ASHA supervisors will not be included owing to hierarchical differences in these two cadres and their potential effects on absorption of intervention content, and thereby on their wellbeing (primary outcome of interest)\n* ASHAs who have difficulties in using a smartphone","FEMALE",{"count":327,"type":21},330,[24],"The purpose of this two-arm, parallel group individual randomized controlled trial is to evaluate the effectiveness of a character-strengths based coaching intervention consisting of a five-day residential workshop focusing on the use of character-strengths to address work-stress in routine situations supplemented by 8- to 10-week remote telephonic weekly coaching sessions to support rural health workers, as they face stressful situations and apply the strategies learnt in the workshop. The arms are: the character-strengths based intervention added to routine health worker supervision (weekly, by the supervisor) and routine supervision alone (control arm). The target sample comprises 330 government contracted 'ASHAs' (rural resident women, lay health workers) in the Sehore district of Madhya Pradesh, one of the most populous and poorest of the states in India. Scores on the 'Authentic Happiness Inventory (AHI)' will serve as the primary outcome for self-reported wellbeing and will be compared between arms at 3-month follow-up. Secondary ASHA-level outcomes will include assessment of self-reported affect, self-efficacy, flourishing, burnout, and motivation. We will also collect exploratory outcomes, including routine service delivery indicators to assess any effect of changes in well-being on ASHA's regular work performance, and resulting patient-level outcomes like satisfaction with services, and depression severity levels after receiving community-based depression care delivered by the ASHAs. We will also evaluate the costs of delivering the intervention and those incurred by ASHAs due to their participation in the intervention. Assessors blind to participant allocation will collect outcomes at baseline, 1-month and 3-month follow-up, as well as at 6-month follow-up, to ascertain differences in outcomes between arms. In addition, scores of ASHAs' self-perceived character strengths will be collected at baseline and 3-month follow-up as exploratory variables.",[32,331,332],"Burnout, Psychological","Mental Health Issue",[334,335,280,336,337,338],"character strengths","community health workers","India","randomized controlled trial","positive psychology","2024-11-18",{"date":341,"type":48},"2024-11-20",{"date":343,"type":48},"2023-08-21",{"date":345,"type":21},"2025-09-30",{"name":347,"class":54},"Templeton World Charity Foundation",{"id":349,"slug":350,"hasResults":11,"nctId":351,"briefTitle":352,"officialTitle":353,"acronym":4,"eligibilityCriteria":354,"healthyVolunteers":63,"sex":91,"minAge":17,"maxAge":4,"enrollmentInfo":355,"targetDuration":4,"studyType":22,"phases":357,"briefSummary":358,"conditions":359,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":363,"lastUpdatePostDateStruct":364,"startDateStruct":365,"completionDateStruct":367,"leadSponsor":369,"locationsCount":259},"100568217","leadership-for-recovery-evaluation-of-an-intervention-programme-for-first-line-healthcare-managers-100568217","NCT06678347","Leadership for Recovery: Evaluation of an Intervention Programme for First-line Healthcare Managers","Leadership for Recovery: Effects of an Intervention Programme for First-line Healthcare Managers on Employees' Recovery","Inclusion Criteria\n\nManagers:\n\nFirst line manager of nursing or laboratory staff in hospital care\n\nEmployees:\n\nHaving a first-line manager who participates in the study\n\nExclusion Criteria\n\nManagers:\n\nLess than 6 months' work experience as a manager at baseline measurement\n\nLess than 50 % employment as a manager\n\nEmployees:\n\nCasual worker\n\nExclusion criterium only for the diary and actigraphy study (employees):\n\nLess than 6 months' work experience in profession at baseline measurement",{"count":356,"type":21},960,[24],"The goal of this intervention study is to evaluate a group intervention programme that aims to support first-line healthcare managers in promoting their employees' recovery through a \"leadership for recovery\".\n\nIn the study, the researchers will investigate if the intervention programme can improve the recovery (including sleep) of healthcare employees. The intervention programme consists of 6 group sessions for managers.\n\nThe main question the study aims to answer are:\n\n\\- Can a group-based intervention programme with a focus on strengthening first-line healthcare managers' leadership for recovery improve their employees' recovery?\n\nThe intervention programme will be delivered to first-line healthcare managers in Swedish hospital care settings. Researchers will compare survey, diary and actigraphy data between employees of 1) managers who participate in the programme and 2) managers who has not participated in the programme.",[360,73,101,32,361,362],"Recovery, Psychological","Insomnia","Fatigue","2024-11-14",{"date":339,"type":48},{"date":366,"type":48},"2024-06-13",{"date":368,"type":21},"2025-12",{"name":370,"class":54},"Karolinska Institutet",{"id":372,"slug":373,"hasResults":11,"nctId":374,"briefTitle":375,"officialTitle":376,"acronym":377,"eligibilityCriteria":378,"healthyVolunteers":63,"sex":91,"minAge":379,"maxAge":4,"enrollmentInfo":380,"targetDuration":4,"studyType":22,"phases":382,"briefSummary":383,"conditions":384,"keywords":391,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":399,"lastUpdatePostDateStruct":400,"startDateStruct":402,"completionDateStruct":404,"leadSponsor":406,"locationsCount":259},"100553627","stress-and-musculoskeletal-health-in-employees-100553627","NCT06488547","Stress and Musculoskeletal Health in Employees","Musculoskeletal Disorders and Stress Management, in Employees","MUStress","Inclusion Criteria:\n\n* Writing and reading greek.\n* Consent to provide their medical history.\n* Consent to be measured with electronic devices.\n\nExclusion Criteria:\n\n* Employees who are close to retirement (at least 2 years before) and those for whom any known factor may prevent them from completing the intervention (eg travel, transfer).\n* Pregnancy.\n* Pacemaker, history of seizures.\n* Diagnosed musculoskeletal injury.\n* Diagnosed diseases such as: osteoarthritis, autoimmune diseases (rheumatoid arthritis, lupus, etc.), stroke, myocardial infarction, malignant neoplasms, psychiatric disease, disability.\n* Systematic reception of cortisone and anti-inflammatory treatment, up to at least three months before the intervention.\n* Drugs or substances.\n* Participation in another interventional program of musculoskeletal rehabilitation, physical therapy, stress management or health promotion.","19 Years",{"count":381,"type":21},57,[24],"This study aims to evaluate potential correlation of stress as estimated by certain biological markers, namely saliva cortisol, Heart rate variability (HRV), Electromyography (EMG) with musculoskeletal system health status, and assess the impact of a stress management intervention..The intervention group will be trained to apply two evidence based stress management techniques and they will be guided with tips and advice about musculoskeletal health.\n\nImpact of the intervention upon measured stress related markers will be assessed.",[385,386,387,388,32,389,390],"Musculoskeletal Diseases or Conditions","Musculoskeletal Pain","Musculoskeletal Health","Stress","Occupation-related Stress Disorder","Medically Unexplained Symptoms",[392,393,394,395,396,397,398],"stress management","stress biomarkers","musculoskeletal health","work-related","biofeedback","saliva cortisol","HRV","2024-06-27",{"date":401,"type":48},"2024-07-05",{"date":403,"type":48},"2024-06-01",{"date":405,"type":21},"2026-12-31",{"name":407,"class":54},"University of Thessaly"]