[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wound-dehiscence-surgical\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wound-dehiscence-surgical":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,59],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":14,"conditions":25,"keywords":35,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":5},"100593309","phase-1-enhancing-wound-perfusion-in-high-risk-lower-extremity-orthopaedic-surgery-a-study-on-nitropaste-using-intraoperative-spy-imaging-100593309",false,"NCT07004764","Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.","Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Feasibility Study on Nitropaste Using Intraoperative SPY Imaging.","SPY NITROPASTE","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Undergoing surgery for one of the following procedures:\n\n  * Current Procedural Terminology (CPT) 28415 - Open reduction calcaneal fracture ± internal\u002Fexternal fixation\n  * CPT-27814 - Open reduction of bimalleolar fracture ± internal\u002Fexternal fixation\n  * CPT-27822 - Open reduction trimalleolar ankle fracture, medial and lateral malleoli only, ± internal\u002Fexternal fix\n  * CPT-27823 - Open reduction trimalleolar ankle fracture, including posterior malleolus, ± internal\u002Fexternal fix\n  * CPT-27826 - Open reduction pilon fracture, internal\u002Fexternal fixation of fibula ONLY\n  * CPT-27827 - Open reduction pilon fracture, internal\u002Fexternal fixation of tibia ONLY\n  * CPT-27828 - Open reduction pilon fracture, internal\u002Fexternal fixation of tibia AND fibula\n  * CPT-27535 - Open reduction unicondylar tibial plateau fracture, ± internal\u002Fexternal fixation\n  * CPT-27536 - Open reduction bicondylar tibial plateau fracture, ± internal\u002Fexternal fixation\n  * CPT-28445 - Open reduction of talus fracture, ± internal\u002Fexternal fixation\n  * CPT-27650 - Primary Achilles tendon repair\n* English-speaking\n* Able to provide informed consent during preoperative clinic visit, in the preoperative nursing area, or on inpatient units.\n\nExclusion Criteria:\n\n* Contraindications to nitroglycerin, including known allergy.\n* Allergy to indocyanine green or components of ICG dye, including allergies to iodine or shell-fish.\n* Severe kidney injury, as determined by attending surgeon and\u002For anesthesiologist, that would impair clearance of ICG dye.\n* Pregnant patients","ALL","18 Years",{"count":20,"type":21},15,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1",[26,27,28,29,30,31,32,33,34],"Achilles Tendon Repairs\u002FReconstructions","Pilon Fracture of Tibia","Tibial Plateau Fracture","Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)","Calcaneus Fractures","Talus Fracture","Wound Infection Deep","Wound Infection Post-Traumatic","Wound Dehiscence, Surgical",[36,37,38,39,40,27,28,41,30,42,43,44,45,46],"Laser-assisted indocyanine green angiography","nitropaste","nitroglycerin","topical nitroglycerin","Achilles tendon repairs\u002Freconstructions","Ankle Fracture (bimalleolar equivalent, bimalleolar, or trimalleolar)","Talus fracture","Wound Dehiscence","Wound infection","tissue perfusion","Orthopaedic surgery","NOT_YET_RECRUITING","2026-03-30",{"date":50,"type":51},"2026-03-31","ACTUAL",{"date":53,"type":21},"2026-11",{"date":55,"type":21},"2027-12",{"name":57,"class":58},"Johns Hopkins University","OTHER",{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":22,"phases":69,"briefSummary":71,"conditions":72,"keywords":73,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100569655","the-comparison-of-interrupted-modified-smead-jones-versus-conventional-continuous-suturing-technique-for-closure-of-rectus-sheath-in-patients-undergoing-laparotomy-for-hollow-viscus-perforation-100569655","NCT06697067","The Comparison of Interrupted Modified Smead-Jones Versus Conventional Continuous Suturing Technique for Closure of Rectus Sheath in Patients Undergoing Laparotomy for Hollow Viscus Perforation.","Farrukh 24","Inclusion Criteria:All patients of both genders with age greater than 18 to 60 years, undergoing emergency laparotomy through midline incision for hollow viscus perforation.\n\nASA grade III -\n\nExclusion Criteria:Patients who had undergone a previous laparotomy for any condition or had an incisional hernia or burst abdomen at presentation.\n\nPatients undergoing laparotomy with anterior abdominal wall injury in the form of muscle, hematoma, disruption or abdominal wall laceration.\n\n\\-","60 Years",{"count":68,"type":21},108,[70],"NA","After taking approval from Board of Studies, IRB \\& ASRB of KEMU, 108 patients fulfilling inclusion criteria will be admitted in Department of General Surgery, East Surgical Ward, Mayo Hospital Lahore through Emergency Department. Firstly patients will be seen in emergency department, history and clinical examination will be done and laboratory investigations and imaging will be done. All the patients aged greater than 18 years undergoing emergency laparotomy for hollow viscus perforation will be included in the study. Informed consent will be obtained. Demographic data including name, age, sex will be recorded.\n\nEmergency laparotomy will be done with midline incision and intra-operative findings will be recorded. Thorough peritoneal lavage will be done and necessary procedures will be carried out for the pathology identified, and abdominal drains will be placed. The patients then will be randomly divided into 2 groups; group A (Experimental Group) undergoing Modified Smead-Jones interrupted suture technique and group B (Reference Group) undergoing conventional continuous suture closure of rectus sheath. In Modified Smead-jones suture technique describe as a far bite starting at 2 cm on the edge of linea from outside-in and then taking a near bite of 0.5 cm on the other side inside-out- a near bite on the same side outside-in and then a far bite on the other side inside-out. The suture was next converted to a horizontal mattress by taking a far bite 1 cm above or below the previous bite on the other side- near bite on the same side, near bite on the other side, and finally a far bite on the same side. The two ends of the suture were tied to approximate the edges of the linea alba9. In conventional continuous closure suture technique I will use number 1 polypropylene suture, care being taken to place each bite 1-1.5 cm from the cut edge of linea alba and successive bites being taken 1cm away from each other The edges of linea alba were gently approximated without strangulation with an attempt to keep a suture to wound length ratio of 4:110.Rectus sheath will be closed by the suture material No.1 polypropylene in both groups.\n\nThe midline laparotomy wound will be managed with daily antiseptic dressing and intravenous antibiotics. All patients will be examined daily till discharge then weekly till 2 weeks and on each visit, a slandered physical examination of abdomen of wound will be done and presence of burst abdomen will be noted. When there are no signs of burst abdomen (after 14 postoperative days) the laparotomy wound will be considered normal. All the data will be collected in accordance to patient's proforma.",[34],[64],"RECRUITING","2024-11-17",{"date":77,"type":51},"2024-11-20",{"date":79,"type":51},"2024-06-06",{"date":81,"type":21},"2025-06-21",{"name":83,"class":58},"King Edward Medical University",1]