[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wound-healing-delayed\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wound-healing-delayed":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100618245","healing-electroceutical-dressing-for-the-recovery-of-open-wounds-hero-100618245",false,"NCT07329114","Healing Electroceutical Dressing for the Recovery of Open Wounds (HERO)","Prospective, Unblinded, Randomized, Controlled Investigation to Evaluate the Clinical Efficacy of PowerHeal™ Bioelectric Bandage in Managing Infected Traumatic Wounds","HERO","Inclusion Criteria:\n\n1. Female and male participants 18-105 years of age\n2. Hospital admission (or boarding in an emergency department or other area awaiting hospital admission) at participating clinical sites in Ukraine\n3. At least one infected traumatic wound(s) between 20-40 cm2 in size. Probable or confirmed wound infection(s) will be determined by on-site physicians' clinical judgment and the presence of two or more of the following clinical indicators of wound infection:\n\n   1. Presence of worsening pain (from the moment of injury)\n   2. Erythema (redness)\n   3. Warmth (heat)\n   4. Edema (swelling)\n   5. Purulent exudate (drainage)\n   6. Delayed healing\n   7. Discoloration\n   8. Friable granulation\n   9. Foul odor\n   10. Wound margin breakdown or necrosis with or without fever\n   11. Pustules, vesicles, boils\n4. Participant or legal representative provides written informed consent prior to investigation procedures\n5. Participant understands and agrees to adhere to planned investigation procedures\n\nExclusion Criteria:\n\n1. Allergy to silver or zinc\n2. Women who are pregnant or nursing\n3. Women of childbearing potential without a documented negative pregnancy test during the current hospitalization or women of childbearing potential who refused pregnancy testing during screening\n4. Sponsor or contract research organization (CRO) staff directly involved in the conduct of the investigation, and site staff supervised by the investigator, and their respective family members\n5. \\> 60 days from the initial traumatic injury\n6. Known prisoner\n7. The patient is expected to be discharged from the hospital within the next 24 hours\n8. Medical condition other than the acute traumatic wound (and its manifestations) that is likely to result in death within 14 days of randomization\n9. Moribund condition, defined as life expectancy less than 48 hours from randomization\n10. Patients undergoing comfort care measures only such that treatment focuses on end-of-life symptom management over prolongation of life\n11. Expected inability or unwillingness to participate in study procedures\n12. In the opinion of the investigator, participation in the investigation is not in the best interest of the patient\n\nNote: Allergies to parabens and acrylates will also be considered. While they are not direct exclusions, participants with these allergies should avoid being enrolled.","ALL","18 Years","105 Years",{"count":21,"type":22},150,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to determine whether the wireless electroceutical dressing (WED) called PowerHeal™ Bioelectric Bandage, improves care of infected wounds by clearing the infection and helping the wound heal better.\n\nThe main hypotheses it aims to answer are:\n\n1. WED promotes wound closure, as determined by wound area measurement\n2. WED manages wound infection in civilian and military wounds in Ukraine, as determined by clinical assessment of wound infection by measuring the numbers and types of relevant microbes.\n\nResearchers will compare to see if PowerHeal™ Bioelectric Bandage the dressing used in the SOC group\n\nParticipants will get their dressings changed per the protocol, wound image and swab will be taken.",[28,29,30,31,32],"Wound Heal","Wound Infection","Wound Healing Delayed","Wound of Skin","Infections",[34],"bandage","RECRUITING","2026-03-04",{"date":38,"type":39},"2026-03-06","ACTUAL",{"date":41,"type":39},"2026-02-11",{"date":43,"type":22},"2027-08",{"name":45,"class":46},"Chandan Sen","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":47},"100613047","an-exploratory-research-on-the-efficacy-and-safety-of-antibacterial-absorbable-dressing-in-chronic-non-healing-wounds-100613047","NCT07261501","An Exploratory Research on the Efficacy and Safety of Antibacterial Absorbable Dressing in Chronic Non-healing Wounds","Inclusion Criteria:\n\n* Age : 18-80 years\n* Wound Type : Chronic non-healing ulcers\\* with no signs of healing progression for ≥1 week\n* Wound Area : 1-35 cm²\n* Infection Status : Local infection, contamination, or colonization\\*\\* as classified by IWII Wound Infection Staging\n* Wound Phase : Late necrotic stabilization phase, granulation phase, or epithelial migration phase\\*\\*\\*\n* Consent : Voluntary participation with signed informed consent\n\nExclusion Criteria:\n\n* Severe Comorbidities : Acute myocardial infarction, heart failure, hepatitis, shock, respiratory failure, or other critical conditions requiring stabilization\n* Uncontrolled Diabetes : Fasting blood glucose \\>15 mmol\u002FL or HbA1c \\>12%\n* Active Wound Hemorrhage : Bleeding precluding standard wound therapy\n* Critical Laboratory Values :\n\nSerum albumin \\\u003C20 g\u002FL Hemoglobin \\\u003C60 g\u002FL Platelet count \\\u003C50×10⁹\u002FL\n\n* Systemic Infection : Disseminated\u002Fsystemic infection requiring antibiotic therapy\n* Malignancy : Advanced cancer patients，Current radiotherapy\u002Fchemotherapy，Malignant (cancer-related) ulcers\n* Untreated Burns : Full-thickness (third-degree) burns without escharotomy\n* Active Autoimmune Disease : Flare-up phase of autoimmune disorders\n* Pregnancy\u002FLactation : Pregnant or breastfeeding women\n* Allergy : Hypersensitivity to absorbable wound repair materials or polyhexamethylene biguanide hydrochloride\n* Non-compliance : Inability to cooperate or psychiatric disorders\n* Investigator's Discretion : Any condition deemed to compromise wound healing or study adherence","18 Months","80 Years",{"count":57,"type":22},30,[25],"Antimicrobial absorbable wound dressing is a novel polyester-based degradable dressing. Previous preclinical studies have demonstrated promising efficacy, with a 3-week wound area reduction rate of 63.53% in large animal models, outperforming foreign counterparts (49.47%), without significant adverse reactions observed during application. Toxicological risk assessment confirms acceptability, and small animal model studies show no abnormalities in toxicity or sensitization. However, current evidence lacks clinical validation, particularly regarding efficacy and safety in chronic non-healing wounds.\n\nThis study integrates modern clinical evaluation methods with chronic wound staging theory to systematically investigate the effectiveness and safety of antimicrobial absorbable wound repair materials in treating chronic non-healing wounds. The research aims to identify optimal indications and provide robust evidence for its clinical efficacy and safety.",[28,30],"2025-11-22",{"date":63,"type":39},"2025-12-03",{"date":65,"type":39},"2025-11-01",{"date":67,"type":22},"2026-11-01",{"name":69,"class":46},"Peking University Third Hospital"]