[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wrinkle-appearance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wrinkle-appearance":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100632761","anti-aging-efficacy-study-on-one-cosmetic-product-containing-mitopure-100632761",false,"NCT07517887","Anti-aging Efficacy Study on One Cosmetic Product Containing Mitopure","Anti-aging Efficacy Study on One Cosmetic Product vs Untreated","HCP-S1","INCLUSION CRITERIA\n\n* Written Informed Consent to participate in the study\n* Written Informed Consent for the use of the images for marketing purposes applies to subgroup participants of study 26.0112.\n* Willingness to actively participate in the study and to come to the scheduled visits\n* Female\n* Male, approximately 10 to 15% with little facial hair\n* From 45 to 65 years of age\n* Healthy skin in the test areas\n* Visible wrinkles in the face (grade 3 to 6 according to proderm wrinkle score)\n\nExclusion criteria\n\n* Female participants: Pregnancy or lactation\n* Drug addicts, alcoholics\n* AIDS, HIV-positive or infectious hepatitis\n* Conditions which exclude a participation or might influence the test reaction\u002Fevaluation\n* Participation or being in the waiting period after participation in cosmetic and\u002For pharmaceutical studies pertaining to the test area\n* Active skin disease at the test area\n* Documented allergies to face\u002Feye care products or their ingredients\n* Diabetes mellitus\n* Cancer not being diagnosed as cured and requiring chemotherapy, irradiation and\u002For hormonal treatment within the last 2 years\n* One of the following illnesses with reduced physical capability\u002Ffitness: asthma (symptom-free allergic asthma is not an exclusion criterion), hypertension (if not adjusted with medication), cardiovascular diseases\n* Epilepsy\n* Wounds, moles, tattoos, scars, irritated skin, excessive hair growth, freckles, etc. at the test area that could influence the investigation\n* Regular use of tanning beds within the last 6 weeks prior to the start of the study\n* Any topical medication at the test area within the last 3 days prior to the start of the study\n* Systemic therapy with immuno-suppressive drugs (e.g. corticosteroids) and\u002For antihistamines (e.g. antiallergics) within the last 7 days prior to the start of the study and throughout the entire course of the study that in the opinion of the investigator may affect the outcome of the study\n* Therapy with antibiotics within the last 2 weeks prior to the start of the study and throughout the entire course of the study that in the opinion of the investigator may affect the outcome of the study\n* Cosmetic surgery procedure in the test area (e.g. laser, facelift) within the last 2 years and throughout the entire course of the study\n* Cosmetic surgery treatments in the test area, e.g. IPL (Intensed Pulsed Light), botox, chemical peel, dermabrasion within the last 2 years prior to the start of the study and throughout the entire course of the study\n* Medical treatment for wrinkle reduction (e.g. peeling with vitamin A or fruit acids) on the face within the last 2 weeks prior to the start of the study and throughout the entire course of the study",true,"ALL","45 Years","65 Years",{"count":22,"type":23},30,"ESTIMATED","INTERVENTIONAL",[26],"NA","The aim of this study is to investigate the impact of a topical product on skin health and aging",[29,30],"Aging","Wrinkle Appearance","RECRUITING","2026-04-24",{"date":34,"type":35},"2026-04-29","ACTUAL",{"date":37,"type":35},"2026-04-22",{"date":39,"type":23},"2026-10-15",{"name":41,"class":42},"Amazentis SA","INDUSTRY",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":17,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":24,"phases":56,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100627263","a-study-to-evaluate-the-efficacy-of-collagen-16-serum-alone-against-and-as-an-adjunct-to-radiesse-biostimulation-procedure-in-female-trial-participants-with-aged-skin-100627263","NCT07446361","A Study to Evaluate the Efficacy of Collagen 16 Serum Alone, Against and as an Adjunct to Radiesse® Biostimulation Procedure in Female Trial Participants With Aged Skin","A Randomized Clinical Study to Evaluate the Efficacy of Collagen 16 Serum Alone, Against and as an Adjunct to Radiesse® Biostimulation Procedure in Female Trial Participants With Aged Skin","Inclusion Criteria:\n\n* Female trial participants aged from 30 to 70 years.\n* Trial participants who are regular users of anti-aging cosmetic products.\n* Trial participants presenting with:\n* Wrinkle visibility score ≥3 and ≤6 on a 10-point visual scale.\n* Fine lines visibility score ≥3 and ≤6 on a 10-point visual scale.\n* Crow's feet wrinkle score ≥2 and ≤4 on the L'Oréal Atlas (volume 1 caucasian type).\n* Skin radiance score ≥3 and ≤6 on a 10-point visual scale.\n* Plumpness score ≥3 and ≤6 on a 10-point visual scale\n\nExclusion Criteria:\n\n* Trial participants who are pregnant, breastfeeding, or planning to become pregnant during the study period.\n* Trial participants who are currently participating in another facial clinical study or who have participated in such a study within 1 month that may interfere with the study outcomes.\n* Trial participants presenting with current flaring or severe inflammatory acne or any active dermatological condition that, in the investigator's opinion, could interfere with study assessments.\n* Trial participants who have undergone ablative laser treatments, microneedling, chemical peels, dermabrasion, non-ablative laser, intense pulsed light (IPL), or injectable procedures within the last 12 months from the day of screening.\n* Trial participants who have undergone biostimulation procedures in the past 6 to 9 months from the day of screening\n* Trial participants with a known allergy to any component of the investigational product(s), comparator product(s), or additional products used in the study.\n* Trial participants presenting with any medical or dermatological condition that, in the investigator's opinion, may compromise trial participant safety or interfere with study conduct or evaluation.\n* Trial participants who are unable or unwilling to comply with the study requirements and instructions.\n* Trial participants who are unable to provide written informed consent.\n* Trial participant with clinically significant history of alcoholism or drug abuse;\n* Trial participant who are employees of MSCR or Sponsor","FEMALE","30 Years","70 Years",{"count":55,"type":23},180,[26],"This study aims at assessing the efficacy of improving skin aging signs of a serum containing collagen 16 combined with a biostimulation device in healthy female subjects aged between 30 and 70 years over a period of 13 weeks.",[30,59],"Skin Quality",[61,62,63,64,65],"anti-aging","cosmetics","collagen 16","biostimulation","placebo serum","NOT_YET_RECRUITING","2026-03-02",{"date":69,"type":35},"2026-03-03",{"date":71,"type":23},"2026-03-01",{"date":73,"type":23},"2026-09",{"name":75,"class":42},"Vichy Laboratoires",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":18,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":24,"phases":86,"briefSummary":89,"conditions":90,"keywords":98,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":110},"100582895","phase-1-autologous-adipose-cells-therapy-100582895","NCT06869252","Autologous Adipose Cells Therapy","Inclusion Criteria:\n\n1. Outpatients who express interest in skin rejuvenation, and\u002For who are experiencing skin conditions, such as winkles, fine lines, loss of skin elasticity, skin pigmentation, scarring.\n2. Outpatients who are experiencing hair loss or hair thinning\n3. Provision of signed and dated informed consent form\n4. Clearly stated willingness to comply with all the procedures of the study and availability of the study\n5. Female and Male aged between 21 to 80 years old 6 Medical clearance by family doctor\n\nExclusion Criteria:\n\n1. Pregnancy or lactation\n2. Known allergic reaction to components of cell culture media\n3. Chronic disease , e.g. cardiovascular disease, diabetes, chronic kidney disease, seizures\n4. Chronic infections, e.g. skin fungi infection, psoriasis\n5. Chronic wound healing\n6. Currently taking hormone therapy\n7. History of cancers and active cancers\n8. Viral infection, e.g. HIV, hepatitis B, influenza, coronaviruses.","21 Years","80 Years",{"count":85,"type":23},40,[87,88],"PHASE1","PHASE2","Autologous Adipose Cell Therapy is a series of process designated to address the demerits of the traditional autologous fat grafting and dermal fillers, while enhancing the versatility and aesthetic outcomes. In this study, the goal is to evaluate the safety and efficacy of Autologous Adipose cell Therapy for skin rejuvenation and hair improvement in human application.",[91,30,92,93,94,95,96,97],"Hair Loss\u002FBaldness","Volume","Fine Lines","Skin Elasticity","Hair Thinning","Skin Pigmentation","Skin Texture",[99,100],"Adipose Cells","Adipocytes","2025-05-30",{"date":103,"type":35},"2025-05-31",{"date":105,"type":23},"2025-08-01",{"date":107,"type":23},"2026-02-01",{"name":109,"class":42},"CERM INC.",2]