[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wrist-fractures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wrist-fractures":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,50,98,120,145,171,196],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100634333","wrist-injury-strengthening-exercise-wise-versus-usual-care-advice-for-improving-pain-and-function-100634333",false,"NCT07538323","Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function","Progressive Resistance and Flexibility Exercises Versus Usual Care Advice for Improving Pain and Function After Distal Radius Fracture in Adults Aged 50 Years or Over in Denmark: the WISE-DK Randomised Trial","WISE-DK","Inclusion Criteria:\n\n* Distal radius fracture treated surgically or non-surgically\n* Willing and able to give informed consent\n\nExclusion Criteria:\n\n* Injury is more than two months old\n* There is evidence that the patient would be unable to participate in therapy or a self-guided exercise program provided by a participating center or adhere to study procedures (including cognitive impairment and fracture\u002Fsurgery complications such as Complex Regional Pain Syndrome)\n* No e-mail address to receive electronic questionnaires\n* Open fractures with a Gustilo \\& Anderson grading \\>1","ALL","50 Years",{"count":20,"type":21},588,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice they would normally receive. The main question it aims to answer is:\n\n• Will participants who receive a therapist-supervised exercise program have better improvement in pain and function, as measured by the Patient Rated Wrist Evaluation questionnaire, six months after their injury?\n\nResearchers will compare these participants with those who receive usual care, which includes advice on self-management, to see if the supervised exercise program leads to greater recovery.\n\nParticipants will:\n\n* Either receive supervised exercise, with a therapy session of up to 60 minutes and two additional sessions of up to 30 minutes each in addition to usual-care, or they will receive solely usual-care, consisting of advice on self-management.\n* Complete questionnaires electronically at baseline, 3-months, and 6-months.",[27,28,29,30,31],"Distal Radius Fracture","Colles Fracture","Wrist Fracture","Wrist Fractures","Fracture Arm",[33,34,35,36],"Exercise","Therapy","Resistance training","Strengthening exercise","RECRUITING","2026-06-26",{"date":40,"type":41},"2026-06-30","ACTUAL",{"date":43,"type":41},"2026-05-12",{"date":45,"type":21},"2029-12",{"name":47,"class":48},"University of Aarhus","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":82,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":49},"100633082","early-functional-response-as-a-predictor-of-clinical-outcomes-in-hand-rehabilitation-a-prospective-feasibility-study-using-a-digital-monitoring-system-100633082","NCT07522060","Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System","Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Clinician-Developed Digital Monitoring System","HANDREHPREDICT","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Hand or upper extremity pathology requiring rehabilitation, including but not limited to: flexor or extensor tendon injuries, peripheral nerve injuries or compression syndromes (including carpal tunnel syndrome, cubital tunnel syndrome), distal radius fractures, metacarpal or phalangeal fractures, joint injuries and instabilities, arthropathy (osteoarthritis, rheumatoid arthritis), trapeziometacarpal osteoarthritis, trigger finger, Dupuytren's disease, DeQuervain tenosynovitis, lateral epicondylitis and post-surgical upper extremity conditions\n* Under clinical responsibility of the principal investigator at the Faculty of Physical Therapy and Rehabilitation, Hacettepe University\n* Expected to attend minimum 8 rehabilitation sessions\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* • Active psychiatric illness precluding participation or completion of assessment tools\n\n  * Severe cognitive impairment precluding understanding of patient-reported outcome measures\n  * Literacy difficulties preventing self-completion of questionnaires\n  * Concurrent enrollment in another interventional clinical study\n  * Refusal to provide written informed consent","18 Years",{"count":60,"type":21},60,"OBSERVATIONAL","This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later. In rehabilitation practice, clinicians make numerous decisions each session regarding exercise type, frequency, duration, and treatment approach. Most of these decisions are currently made without systematic longitudinal data. This study addresses three fundamental questions using data collected during routine clinical care: (1) Can the rate of improvement in the first weeks of treatment predict functional status months later, across both session-based and milestone-based time points? (2) Are there meaningfully different recovery profiles among hand rehabilitation patients? (3) Is there measurable variation in clinical decision-making among patients with similar profiles, and does this variation relate to outcomes? A digital patient monitoring platform developed by the principal investigator, a physiotherapist and academic researcher specializing in hand rehabilitation serves as the data collection infrastructure. The platform records standard clinical assessment measures in a structured format and has been in active clinical use at Hacettepe University prior to this study. For research purposes, the system has been expanded to include structured capture of patient-reported outcomes, patient global impression of change, treatment protocol coding, home exercise adherence, and automated calculation of early response metrics.\n\nThis is a 12-month prospective observational cohort study enrolling a minimum of 60 patients. Data are stored securely on the university's institutional network. Patients are anonymized using identification codes. The study is subject to Hacettepe University Ethics Committee approval and participant informed consent. Findings are expected to generate evidence supporting data-driven clinical decision-making in rehabilitation and to provide a feasibility foundation for a larger multi-center study.",[64,65,66,67,68,69,70,71,30,72,73,74,75,76,77,78,79,80,81],"Hand","Hand Therapy","Upper Extremity","Prediction Models","Hand Injuries","Hand Injuries and Disorders","Hand Arthritis","Tendon Injuries","Carpal Tunnel Syndrome (CTS)","Peripheral Nerve Injuries","Upper Extremity Injuries","Wrist Injuries","Finger Injuries","Trigger Finger","Trapeziometacarpal (TMC) Arthrosis","DeQuervain's Tenosynovitis","Cubital Tunnel Syndrome","Postoperative Rehabilitation",[83,84,85,86,87],"digital health monitoring","real-world evidence","clinical decision support","upper extremity rehabilitation","early response prediction","NOT_YET_RECRUITING","2026-04-03",{"date":91,"type":41},"2026-04-13",{"date":93,"type":21},"2026-06-15",{"date":95,"type":21},"2027-06-01",{"name":97,"class":48},"Hacettepe University",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":49},"100545258","wrist-fractures-management-with-arthroscopic-assistance-under-walant---exploratory-study-100545258","NCT06379555","Wrist Fractures Management With Arthroscopic Assistance Under Walant - Exploratory Study","WALANPOIGNE","Inclusion Criteria:\n\n* Patient, male or female, aged ≥ 18 and \\\u003C 70 years\n* Patient with a displaced articular fracture of the distal radius (unilateral wrist fracture)\n* Patient treated on ambulatory way\n* Patient affiliated to or beneficiary of a social security system\n* French speaking patient, having signed informed consent\n\nExclusion Criteria:\n\n* Patient with previous infection or wrist bone surgery\n* Patient with multiple fractures or with bilateral wrist fractures\n* Patient with associated fracture with the wrist fracture\n* Patient with \"pathological\" bone\n* Protected patient: adult under guardianship, curatorship or other protection legal, deprived of liberty by judicial or administrative decision\n* Patient hospitalized without consent","70 Years",{"count":107,"type":21},12,[24],"Wrist articular fractures are more difficult to treat and rehabilitation takes longer. Furthermore, these joint fractures are frequently accompanied by ligament lesions of the carpal bones.\n\nFor these reasons, it is strongly recommended to check the interior of the wrist joint. This check can be done with wrist arthroscopy. Therefore, fracture reduction can be improved, \"step of stairs\" can be eliminated under arthroscopic control and ligament rupture of carpal bones can be treated.\n\nWALANT anesthesia (Wide Awake Local Anesthesia No Tourniquet) designates a new local anesthesia technique. This technique which allows to maintain the arm or fingers mobility offers several significant advantages:\n\n* Greater precision of the surgical procedure.\n* A reduction in discomfort, risks and related adverse effects to anesthesia.\n* Faster recovery.\n\nWALANT technique is very comfortable for patient and fits perfectly with principles of Enhanced Recovery in Surgery.\n\nIn this context, this study is based on the hypothesis that it is possible to combine arthroscopy and the WALANT anesthesia technique for reducing wrist fractures",[30],"2025-11-18",{"date":113,"type":41},"2025-11-24",{"date":115,"type":41},"2024-11-06",{"date":117,"type":21},"2027-06-30",{"name":119,"class":48},"GCS Ramsay Santé pour l'Enseignement et la Recherche",{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":126,"eligibilityCriteria":127,"healthyVolunteers":128,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":129,"targetDuration":4,"studyType":22,"phases":131,"briefSummary":133,"conditions":134,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":49},"100529840","phase-3-supraclavicular-bupivacaine-vs-supraclavicular-liposomal-bupivacaine-for-orthopedic-wrist-surgery-100529840","NCT06179004","Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery","Randomized Controlled Trial of Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery","Vs","Inclusion Criteria:\n\n* Age greater than or equal to 18\n* Scheduled for orthopedic wrist surgery at University of North Carolina at Chapel Hill.\n\nExclusion Criteria:\n\n* Contraindications to regional anesthesia\n* Emergent surgery Open fractures will be treated emergently and will not allow adequate lead time for enrollment in this study. Also, open fractures are usually accompanied by other traumatic injuries that would confound the pain related outcomes in this study.\n* Significant peripheral neuropathy or neurological disorder affecting the upper extremity\n* Pregnancy Pregnant women have physiologic changes that make them more sensitive to local anesthetics. That would introduce a confounding element in interpreting the effectiveness of the peripheral nerve blocks being studied.\n* Cognitive or psychiatric condition that might affect patient assessment and\u002For inability to provide informed consent.",true,{"count":130,"type":21},100,[132],"PHASE3","Orthopedic wrist procedures often cause significant postoperative pain. A supraclavicular nerve block is an effective and proven method to help reduce postoperative pain and decrease opioid use around the time of upper extremity surgery. Liposomal bupivacaine (Exparel) has been approved for use around the brachial plexus, but its analgesic efficacy has limited data. The investigators' goal is to evaluate the effectiveness of Exparel as compared to plain bupivacaine. The investigators hope to ensure the quality of pain control around the time of distal radius fracture repair and reduce the variability of care at the investigators institution by prospectively and rigorously collecting perioperative data during this study.",[135,30],"Distal Radius Fractures","2025-10-23",{"date":138,"type":41},"2025-10-24",{"date":140,"type":41},"2024-04-10",{"date":142,"type":21},"2026-10",{"name":144,"class":48},"University of North Carolina, Chapel Hill",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":17,"minAge":152,"maxAge":18,"enrollmentInfo":153,"targetDuration":4,"studyType":22,"phases":155,"briefSummary":156,"conditions":157,"keywords":158,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":49},"100569755","unilateral-training-of-the-uninjured-limb-on-clinical-outcomes-in-patients-with-surgically-treated-radius-fracture-100569755","NCT06698367","Unilateral Training of the Uninjured Limb on Clinical Outcomes in Patients with Surgically Treated Radius Fracture","Addition of Unilateral Training of the Uninjured Limb to Standard Rehabilitation on Grip Strength and Manual Dexterity of Patients with Surgically Treated Distal Radius Fracture.","Inclusion Criteria:\n\n* Age between 30-50 years\n* Radiological diagnosis of unilateral distal radius fracture without concomitant fractures.\n* Fracture treated surgically.\n\nExclusion Criteria:\n\n* Patients with lesion of the triangular fibrocartilage.\n* Patients with distal radius fracture with consolidation disorders.\n* Patients with health conditions that cause pain or affect the motor skills of the upper limb (radiocarpal osteoarthritis, carpal tunnel syndrome, Quervain's tenosynovitis, neurodegenerative diseases, sequelae of stroke)\n* Patients with multi-site pain or chronic polyarticular diseases such as osteoarthritis or rheumatoid arthritis.\n* Unstable cardiovascular, respiratory, systemic or metabolic conditions that do not allow high-intensity physical exercise.\n* Patients who are taking nutritional supplements that interfere with the regulation of skeletal muscle strength and mass (example: whey protein, creatine, etc.)\n* Inability to understand, read and\u002For speak the Spanish language.","30 Years",{"count":154,"type":21},52,[24],"The objective will be to determine the effectiveness of adding unilateral upper limb postoperative training to standard rehabilitation compared to standard rehabilitation on maximum grip strength and manual dexterity in patients aged 30-50 years with surgically treated distal radius fracture. It is presumed that the addition of unilateral upper limb training will significantly improve maximum grip strength and manual dexterity at the end of the intervention period compared to the group receiving only standard rehabilitation.\n\nPatients who agree to participate in this research will be randomly assigned to a control group (standard rehabilitation with unilateral training with mobility exercises) or an experimental group (standard rehabilitation with unilateral high-intensity strength training). The duration of the postoperative intervention will be 12 weeks. The primary variables are maximum grip strength and manual dexterity. Secondary variables are wrist mobility, forearm circumference, maximum voluntary isometric strength, functionality and health-related quality of life. Results will be measured at 0, 6 and 12 weeks postoperative.",[30,135],[159,160,161,33],"Distal radius fracture","Cross-education","Rehabilitation","2024-11-27",{"date":164,"type":41},"2024-12-03",{"date":166,"type":21},"2025-01",{"date":168,"type":21},"2027-08",{"name":170,"class":48},"Universidad Catolica de Temuco",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":178,"enrollmentInfo":179,"targetDuration":4,"studyType":22,"phases":181,"briefSummary":182,"conditions":183,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":49},"100544194","physiotherapy-vs-telerehabilitation-after-volar-plating-of-distal-radius-fracture-100544194","NCT06365710","Physiotherapy vs Telerehabilitation After Volar Plating of Distal Radius Fracture","A Randomized Controlled Trial Comparing Traditional Physiotherapy vs Telerehabilitation After Volar Plating of Distal Radius Fracture: a Study Protocol","Inclusion Criteria:\n\n* Distal radius fracture, which applies the surgical requirements\n* age between 18 to 65 years\n* Non concomitant injuries including ligament injuries and distal ulna fractures, however ulnar styloid avulsion is accepted\n* No significant comorbidities\n* No previous problems with the examined hand\n* Ability to understand Finnish fluently\n\nExclusion Criteria:\n\n* High energy or multiple injuries\n* Open fractures\n* Injury of both upper extremities\n* Other operative injury on the same side\n* Rheumatoid arthritis of other inflammatory joint disease\n* Heavy smoker (over 20 cigarettes per day)\n* Disease of medication slowing ossification\n* Alcohol or drug abuse\n* Psychiatric disorder with poor treatment balance\n* Neurological disorder which affects the function of the injured extremity\n* Fixation material other than a volar locking plate\n* Fracture fixation is not stable enough to start rehabilitation after 14 days","65 Years",{"count":180,"type":21},84,[24],"Trial purpose is to research the outcome comparing traditional physiotherapy vs telerehabilitation after volar plating of distal radius fracture.\n\nPatients with distal radius fracture that meet the operative criteria set by the Finnish Current Care guidelines are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo operative treatment and traditional physiotherapy vs telerehabilitation.\n\nBaseline data is collected preoperatively and patients are followed at 1, 3 and 12 months after enrollment. The primary end-point is 3 months and the primary outcome is the Patient-Rated Wrist Evaluation (PRWE).",[184,185,186,161,30],"Orthopedic Procedures","Physical Therapy Modalities","Postoperative Care","2024-10-29",{"date":189,"type":41},"2024-10-31",{"date":191,"type":41},"2022-11-24",{"date":193,"type":21},"2026-01-31",{"name":195,"class":48},"Töölö Hospital",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":128,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":22,"phases":205,"briefSummary":206,"conditions":207,"keywords":209,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":4},"100547377","efficacy-of-intra-articular-corticosteroid-injections-on-clinical-outcomes-in-patients-with-operative-distal-radius-fractures-100547377","NCT06407180","Efficacy of Intra-Articular Corticosteroid Injections on Clinical Outcomes in Patients With Operative Distal Radius Fractures","Efficacy of Intra-Articular Corticosteroid Injections on Clinical Outcomes in Patients With Operative Distal Radius Fractures: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age more than 18 years old\n2. Closed unstable distal radius fracture unstable type which need surgical management\n3. Received procedure ORIF with plate and screws at injured wrist\n\nExclusion Criteria:\n\n1. History of corticosteroid allergy\n2. Poor Diabetes controlled (HbA1C) \\> 8\n3. Who need Ritonavir while enter this study\n4. Unable to follow up until the end of projects\n5. Unable to do questionnaires\n6. Infection around injured wrist\n7. Tear tendon at injured wrist\n8. Open fracture of injured wrist",{"count":204,"type":21},58,[24],"The randomized controlled study which compare clinical outcomes (functional score) in patients with distal radius fractures who underwent open reduction with internal fixation and received intra-articular steroid injections to those who received placebo injections.",[30,208],"Intraarticular Injection",[30,210,211],"intraarticular injection","corticosteroids","2024-05-06",{"date":214,"type":41},"2024-05-09",{"date":216,"type":21},"2024-07-01",{"date":218,"type":21},"2026-12-31",{"name":220,"class":48},"Teeradon Waewworawit"]