[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"youth-mental-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:youth-mental-health":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100053377","cohort-network-for-adolescents-and-youth-with-multiple-mental-health-conditions-100053377",false,"NCT07699159","Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions","Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions (CALM): A Master Observational Trial","CALM","Inclusion Criteria:\n\nThe participant must meet all of the inclusion criteria to be eligible for this research study:\n\n* Light Phenotype Eligibility Must sign and date the informed consent form, or provide assent and have a Substitute Decision Maker provide informed consent; Aged 11-24 years old at the time of screening; Any person within age criteria who has previously sought, is seeking, or is accessing mental health services; Are able to complete assessments in English.\n\nDeep Phenotype Eligibility Must be part of the CALM light phenotype cohort; Must sign and date the deep phenotyping informed consent form, or provide assent and have a Substitute Decision Maker provide informed consent.\n\nLight Phenotype Caregiver Participant Eligibility:\n\nAny caregiver of a CALM child\u002Fyouth participant is eligible to participate in the study, insofar as the child\u002Fyouth participant has consented to the light phenotype cohort and has agreed for their caregiver to be contacted to participate in the study; Must sign and date the informed consent form.\n\nDeep Phenotype Caregiver Participant Eligibility:\n\nAny caregiver of a CALM child\u002Fyouth participant is eligible to participate in the study, insofar as the child\u002Fyouth participant has consented to the deep phenotype cohort and has agreed for their caregiver to be contacted to participate in the study; Must sign and date the informed consent form.\n\nExclusion Criteria:\n\nAn individual who meets any of the following criteria will be excluded from participation in this research study:\n\nLight Phenotype Does not provide informed consent (for those with the capacity to consent) or assent (for those who lack the capacity to consent); For those individuals who lack the capacity to consent, the inability of the parent\u002Flegal guardian to provide informed consent for the youth is also an exclusion criterion; Those who lack capacity to consent include individuals who are non-verbal or unable to speak any English.\n\nDeep Phenotype Unable to participate in deep phenotyping protocol (e.g., MRI contraindication, uncorrected vision or hearing impairments that would interfere with data collection, unwillingness to complete assessments); No exclusion criteria are based on race, ethnicity, sex or gender.\n\nLight Phenotype Caregiver Participant Ineligibility:\n\nCaregivers of CALM child\u002Fyouth participants are ineligible to participate in the study if:\n\nThe child\u002Fyouth participant does not agree for their caregiver to be contacted to participate in the study; The child\u002Fyouth participant is not participating in the light phenotype cohort; Does not provide informed consent (for those with the capacity to consent). Those who lack capacity to consent include individuals who are non-verbal or unable to speak any English.\n\nDeep Phenotype Caregiver Participant Ineligibility:\n\nCaregivers of CALM child\u002Fyouth participants are ineligible to participate in the study if:\n\nThe child\u002Fyouth participant does not agree for their caregiver to be contacted to participate in the study; The child\u002Fyouth participant is not participating in the deep phenotype cohort (i.e., is only participating in the light phenotyping cohort); Does not provide informed consent (for those with the capacity to consent). Those who lack capacity to consent include individuals who are non-verbal or unable to speak any English.","ALL","11 Years","24 Years",{"count":21,"type":22},1620,"ESTIMATED","OBSERVATIONAL","The Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions (CALM) Master Observational Trial is a prospective, longitudinal observational study that seeks to improve clinical care for youth with multiple mental health conditions (MMHC), also known as mental health multimorbidity in the literature. MMHC is conceptualized as the presence of two or more mental health diagnoses under the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). MMHC is common in youth seeking mental health services and is associated with less favorable outcomes and greater health services utilization. Mental health disorders also accumulate in youth over time. The Master Observational Trial (MOT) will investigate MMHC in critical developmental periods in youth and identify risk and protective factors that will provide a mechanistic understanding of how MMHC develops over time. A subset of participants will also enroll in a Deep Phenotyping Cohort, which includes enhanced clinical and cognitive assessments and multimodal neuroimaging to investigate neurobiological mechanisms underlying MMHC and identify potential biomarkers of illness complexity and progression.\n\nIn the near future, we aim to add to the current protocol to embed both a clinical trials network for youth mental health in Ontario and Calgary within the CALM study and add digital phenotyping using wearable technology to generate digital and physiological markers of MMHC. The current protocol focuses on establishing the longitudinal MOT cohort and Deep Phenotype Cohort only as a first step towards these long term CALM goals.",[26,27,28],"Multiple Mental Health Conditions","Child Mental Health","Youth Mental Health",[30,31,32,33,34],"multiple mental health conditions","child and youth mental health","mental health multimorbidity","master observational trial","deep phenotyping cohort","RECRUITING","2026-07-07",{"date":38,"type":39},"2026-07-13","ACTUAL",{"date":41,"type":39},"2025-03-04",{"date":43,"type":22},"2028-03-31",{"name":45,"class":46},"Centre for Addiction and Mental Health","OTHER",6,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":71,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":85,"leadSponsor":87,"locationsCount":89},"100634174","community-connections-through-native-hawaiian-cultural-values-to-strengthen-youth-resilience-health-and-well-being-100634174","NCT07536256","Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being","Kamaehu o ke Kaiāulu: Fostering Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being","Kamaehu","Inclusion Criteria:\n\n* youth 12 to 25 years of age;\n* live in the Wai'anae zip code 96792;\n* utilize Waianae Coast Comprehensive Health Center (WCCHC) for their healthcare, including the WCCHC School-based Health Centers;\n* assessed by WCCHC providers as being \"at-promise\" or having a physical or behavioral\u002Fmental health concern that may benefit from further support from Kaiona CBO Programs. Conditions may include chronic disease risk factors such as asthma, obesity, diabetes, or prediabetes, as well as behavioral health concerns.\n\nExclusion Criteria:\n\n* Rather than strict exclusionary criteria, we will rely on the onboarding process that allows for screening for program fit at 4 levels: the referring Pediatric\u002FBehavioral Health provider, the Community Connections Manager, the youth participant\u002Ffamily member, and the receiving CBO. All 4 of these levels will need to assess a potential participant as fit to participate. General considerations include ability to work in groups with other youth, ability to be outdoors for hours at a time, and ability to receive basic instruction and complete basic physical and cognitive tasks associated with the program independently. All 4 layers will also have the opportunity to end the youth's participation in the program at any point if serious safety or health concerns arise for the participant or others involved in the program. If a participant needs to leave a program, the Community Connections Manager will remain engaged with the youth and family to explore other options through the pilot or elsewhere.","12 Years","25 Years",{"count":59,"type":22},100,"INTERVENTIONAL",[62],"NA","The goal of this pilot clinical trial is to learn if a community referral program can improve services for youth with mental health and chronic health conditions in a predominantly Native Hawaiian and Pacific Islander community. The main questions the trial aims to address are:\n\n* What is the best way for a community health center to connect youth with community programs rooted in cultural practices and traditions?\n* Does participation in community programs engage youth and mental health and chronic health outcomes?\n\nParticipants will:\n\n* Participate in a community program for youth that will strengthen connection to 'āina (land) and culture. Programs in the summer are 5 hours per day, 4 days a week, for 4 weeks. Programs in the school-year are 2.5 hours per day, 2 days a week, for 16 weeks.\n* Take surveys on their demographics, general well-being, mental health, and chronic health conditions they may have at 4 different times: Before the program begins, immediately after the program finishes, 3-4 months after finishing, and 6-8 months after finishing.\n* Have an adult family member complete surveys on their youth's demographics and general well-being at the same 4 times",[65,66,67,28,68,69,70],"Chronic Disease","Adolescent Asthma","Obesity & Overweight","Youth Obesity","Prediabetes","Asthma",[72,73,74,75,76,77,78,79,80],"Adolescent Health Services","Community Health Centers","Mental Health Services","Native Hawaiian or Other Pacific Islander","Community Health Services","Adolescent","Young Adult","Child","youth mental health","2026-04-10",{"date":83,"type":39},"2026-04-17",{"date":81,"type":39},{"date":86,"type":22},"2028-08-31",{"name":88,"class":46},"Waianae Coast Comprehensive Health Center",1]