[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"zinc-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:zinc-deficiency":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100457421","effects-of-daily-beef-intake-as-a-component-of-a-heart-healthy-diet-on-cellular-zinc-100457421",false,"NCT05236374","Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc","Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet, on Cellular Zinc Status and Vascular Function in Older Adults","Inclusion Criteria:\n\n* Male or postmenopausal female 55-70 years of age\n* Women: lack of menses for at least two years.\n* Subject is willing and able to comply with the study protocols.\n* Subject is willing to participate in all study procedures\n* Self-reported stable dose of prescribed medications for a minimum of 6 months\n* BMI 18.5 - 29.9 kg\u002Fm2\n\nExclusion Criteria:\n\n* Self-reported use of daily anticoagulation agents including aspirin, NSAIDs\n* Prescribed metaformin, statins or medications known to interfere with zinc, protein, or lipid metabolism\n* Vegan, Vegetarians, food faddists or those consuming a non-traditional diet (e.g. Adkins, Keto, Paleo, etc.)\n* Fruit consumption ≥ 3 cups\u002Fday\n* Regular consumption of strawberries (2-3 servings\u002Fweek)\n* Vegetable consumption ≥ 4 cups\u002Fday\n* Coffee\u002Ftea ≥ 3 cups\u002Fday\n* Dark chocolate ≥ 3 oz\u002Fday\n* Alcohol intake greater than 2 drinks in a day for men, or 1 drink in a day for women.\n* Self-reported restriction of physical activity due to a chronic health condition\n* Self-reported chronic\u002Froutine high intensity exercise\n* Self-reported diabetes\n* Blood pressure ≥ 140\u002F90 mm Hg\n* Self-reported renal or liver disease\n* Self-reported heart disease, which includes cardiovascular events and stroke\n* Peripheral artery disease Raynaud's syndrome or disease\n* Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT\n* Self-reported cancer within past 5 years\n* Self-reported malabsorption\n* Unwillingness to stop any supplement use six weeks prior to study initiation, including multivitamin\u002Fmineral, powders, herbal, plant or botanical, pro- and prebiotics, and oil supplements.\n* Smoking, vaping, cannabis use\n* Current enrollee in a clinical research study.",true,"ALL","55 Years","70 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater effect on health outcomes. Specifically, whether beef, as a component of a healthy meal, will promote the absorption of zinc into cells, where the zinc will have greater effects on zinc-dependent metabolic processes supporting cardiovascular health. To maximize the observability of these beef-related effects, individuals who are 55- to 70-year-old who generally have a higher risk of zinc deficiency and cardiovascular disease will be enrolled.",[28,29,30,31],"Zinc Deficiency","Inflammation","Metabolic Diseases","Vascular Diseases","RECRUITING","2026-02-04",{"date":35,"type":36},"2026-02-09","ACTUAL",{"date":38,"type":36},"2022-10-01",{"date":40,"type":22},"2026-12-31",{"name":42,"class":43},"University of California, Davis","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":44},"100532954","higher-and-standard-doses-of-enteral-zinc-supplementation-in-very-preterm-infants-100532954","NCT06219525","Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants","Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants: A Randomized Controlled Trial","ZnVeryPT","Inclusion Criteria:\n\n* Very preterm neonates (gestational age \\[GA\\]: 24 0\u002F7-32 6\u002F7 weeks and BW: 401-1800 grams) were consecutively admitted in the NICU and NMCU\n* Body weight at enrollment less than 800 grams\n* Stable neonates and full enteral feeding (150 mL\u002Fkg\u002Fday) at least for a few days\n\nExclusion Criteria:\n\n* Outborn neonate who was admitted in study center after 7 days of life\n* Congenital infections\n* Malformations, syndromes, or genetic defects\n* Evidence of culture proven sepsis or necrotizing enterocolitis or death diagnosed before enrollment\n* Gastrointestinal (GI) surgery or high GI fluid output (usually ileostomy losses)\n* Unstable neonate during weighing including on intercostal drainage tube or drainage\n* Neonates need diuretics more than 7 days\n* Severe birth asphyxia (5-minute Apgar score less than 4)\n* Parents' decision not to participate the study",{"count":54,"type":22},120,[25],"The goal of this randomized clinical trial is to compare the effect of higher (10 mg per day) versus standard (1 mg per day) doses of zinc supplementation The main questions it aims to answer are:\n\n* Growth velocities and delta z-scores during the date of start intervention until the end of the time interval (at least 2 weeks of intervention on date of 44 weeks of postmenstrual age or discharge whichever came first) in very preterm infants with a birthweight less than1800 grams.\n* Growth and neurodevelopment at 24 months postnatal age",[58,28],"Very Preterm Infants",[60,61,62,63,64],"Growth and Development","Mortality","Newborn","Premature Infant","Zinc","2024-09-14",{"date":67,"type":36},"2024-09-19",{"date":69,"type":36},"2024-04-02",{"date":71,"type":22},"2027-12-31",{"name":73,"class":43},"Prince of Songkla University"]