18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia

Trial statusAvailable
Trial phaseNot listed
Trial typeExpanded Access
Biological sexAll
AgeNot listed
SponsorChildren's Hospital of Philadelphia

About this trial

This purpose of this study is to determine the ability of an 18F-fluoro-L-dihydroxyphenylalanine (18F-DOPA) PET (Positron Emission Tomography) scan to detect a focal lesion of hyperinsulinism and determine the location in patients with congenital hyperinsulinism, Beckwith Wiedemann Syndrome and suspected insulinoma. Safety data will be collected.

Eligibility criteria

Qualifiers

Subjects of any age with hyperinsulinemic hypoglycemia, diagnosed by a fasting test and/or response to glucagon stimulation.

Subjects who are eligible for pancreatic surgery regardless of prior pancreatic surgery

Disqualifiers

Pregnant or lactating females

Any other major illness or condition that in the investigator's judgment will substantially increase the risk associated with the subject's participation in this study

Subjects who are not a candidate for pancreatic surgery

Trial design

Treatments tested in this trial

  • 18F-DOPA

Treatment groups

No treatment groups listed