About this trial
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis. We plan to compare the ability of three demensional-magnetic resonance elastography (3D-MRE) to two demensional-magnetic resonance elastography (2D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis.
Eligibility criteria
Qualifiers
age > 18 years old
confirmed cirrhosis (laboratory, imaging and clinical symptoms)
with 3D-MRE and 2D-MRE within 1 month prior to HVPG measurement
written informed consent
Disqualifiers
any previous liver or spleen surgery
liver cancer; chronic acute liver failure
acute portal hypertension
unreliable HVPG, 3D-MRE or 2D-MRE results due to technical reasons
Trial design
Treatments tested in this trial
- 3D-MRE
- HVPG
- 2D-MRE
- HVPG