3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features
ConditionMeningioma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorShengjing Hospital
About this trial
This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to determine whether MRE can serve as a noninvasive imaging biomarker for surgical planning, risk stratification, and prediction of tumor behavior.
Eligibility criteria
Qualifiers
All patients undergoing meningeoma resection surgery are eligible for inclusion in the study cohort.
Disqualifiers
Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings)
Pregnant women in the first trimester (within three months)
Patients with severe claustrophobia or anxiety
Patients with severe fever
Trial design
Treatments tested in this trial
- Magnetic Resonance Elastography
- Intraoperative Assessment and Recording
Treatment groups
300 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov