68Ga-FAPI PET/CT Imaging for Diagnosis, Grading, and Efficacy Evaluation of Myelofibrosis.

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe First Affiliated Hospital of Xiamen University

About this trial

To evaluate the diagnostic efficacy of 68Ga FAPI PET/CT in myelofibrosis and to identify fibrosis grades.

To evaluate the diagnostic efficacy of 68Ga FAPIPET/CT imaging in patients with myelofibrosis, compared with conventional CT.

Eligibility criteria

Qualifiers

Age ≥18 years old;

Cohort 1: Patients with suspected or confirmed myelofibrosis; Cohort 2: Patients with primary/secondary myelofibrosis who were not treated with ruxolitinib.

The expected survival time is over 3 months

Voluntarily sign informed consent.

Disqualifiers

Known allergic history to 68Ga FAPI or its excipients;

Patients who can not tolerate intravenous drug administration (such as needle fainting and blood fainting history);

Those who are not suitable for or unable to complete imaging tests such as PET due to special reasons, including claustrophobia and radiophobia;

pregnant and lactating women;

Trial design

Treatments tested in this trial

  • 68Ga FAPI PET/CT

Treatment groups

90 Participants
are divided into 2 treatment groups