This study is a registry-based cohort investigation, prospectively enrolling patients who were diagnosed with acute myocardial infarction and underwent primary percutaneous coronary intervention (PCI) at Zhongshan Hospital, Fudan University, between January 1, 2009, and December 31, 2028. Baseline clinical characteristics, procedural details, laboratory results, and medication records will be systematically collected and documented. The clinical follow-up will encompass both in-hospital monitoring and post-discharge surveillance extending up to two years after the procedure.
Elevated or decreasing levels of cardiac troponin T, with at least one measurement exceeding 0.014 ng/mL;
Presence of at least one of the following: symptoms of myocardial ischemia; newly onset ischemic changes on ECG; pathological Q wave; imaging evidence of new loss of viable myocardium or regional wall motion abnormalities consistent with ischemia; coronary angiography confirming the presence of a thrombus;
Undergoing primary PCI;
Voluntary informed consent to participate in the study.
Inability to complete emergent PCI (e.g., due to intraoperative complications or inability to tolerate the procedure).
Prior administration of thrombolytic therapy before PCI.
Diagnosis of type 2 or type 3 myocardial infarction.
This study is a registry-based cohort investigation, prospectively enrolling patients who were diagnosed with acute myocardial infarction and underwent primary percutaneous coronary intervention (PCI) at Zhongshan Hospital, Fudan University, between January 1, 2009, and December 31, 2028.
Cohort
Prospective
Collection of baseline characteristics
Other interventionCollection of baseline clinical characteristics, procedural details, laboratory results, and medication records
Incidence of MACCE during hospitalization
Major adverse cardiovascular and cerebrovascular events (MACCE) occurring during hospitalization, including all-cause death, recurrent myocardial infarction, ischemia-driven repeat revascularization, malignant arrhythmias, acute heart failure, cardiogenic shock, and cerebrovascular accidents
Incidence of MACCE during long-term follow-up
Major adverse cardiovascular and cerebrovascular events (MACCE) occurring during out-of-hospital follow-up, including all-cause death, recurrent acute myocardial infarction, ischemia-driven repeat revascularization, rehospitalization for acute heart failure, and cerebrovascular accident.
Incidence of bleeding events during hospitalization
Various bleeding events during hospitalization
Incidence of gout flare during hospitalization
Gout flare during hospitalization
Incidence of myocardial perfusion impairment during primary PCI
TIMI \< 3
Cardiac function status during long-term follow-up
Document the changes in left ventricular ejection fraction (LVEF) during long-term follow-up. A normal LVEF is over 53%, while an LVEF \<50% indicates impaired cardiac systolic function.
The Incidence of Malignant Tumors
The Incidence of Malignant Tumors During Long-Term Follow-Up
Click on the lead sponsor to view all of their trials.
