A Clinical Study of Hanlikang and BTK Inhibitors in the Treatment of Newly Diagnosed Mantle Cell Lymphoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorZhengzhou University

About this trial

An open-label, single-arm, multicenter, prospective clinical study of Hanlikang and BTK inhibitors in the treatment of newly diagnosed mantle cell lymphoma

Eligibility criteria

Qualifiers

Age 18-70, ECOG score 0-2;

Estimated survival time >6 months;

Mantle cell lymphoma was confirmed by pathology.

Acceptable hematological indexes without chemotherapy contraindications; Neutrophil absolute value ≥1.0×10^9 /L, PLT≥75×10^9 /L, hemoglobin ≥80g/L (except patients with lymphoma bone marrow infiltration);

Disqualifiers

Patients with definite neuropathy or psychosis, including dementia or seizures, a history of psychotropic substance abuse and inability to abstinence, or other substantial lesions that may increase CNS toxicity;

Participating in other clinical trials or participating in other clinical investigators 4 weeks before enrollment (except those not receiving treatment);

Systemic autoimmune disease or immune deficiency;

Refusing to collect blood samples;

Trial design

Treatments tested in this trial

  • Rituximab

Treatment groups

100 Participants
are divided into 1 treatment group

Sponsors and collaborators