A Clinical Study of Personalized Self-DC Vaccine Targeting Neoantigen in Treatment of Advanced Solid Tumor

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorFudan University

About this trial

This is a clinical study of personalized self-DC vaccine targeting neo-antigen (Neo-DC vaccine) in the treatment of advanced solid tumors.

Eligibility criteria

Qualifiers

18-75 years.

Histologically or cytologically confirmed advanced solid tumor, with at least one tumor lesion measurable (basis RECIST1.1 standard).

HLA typing was HLA-A0201/1101/2402 (containing at least one of the typing, according to the central laboratory issued).

Paraffin-embedded tumor tissue sections or biopsy tumor tissues within 3 years (for tumors with easy sampling).

Disqualifiers

Pregnant or lactating women.

Patients with a history of severe immediate allergies to the cells and any drugs used in this study.

Those with a history of organ transplantation.

Known central nervous system metastasis.

Trial design

Treatments tested in this trial

  • DC Vaccine

Treatment groups

9 Participants
are divided into 1 treatment group

Sponsors and collaborators