A Clinical Study on the Efficacy and Safety of Reduning Injection in the Treatment of Chikungunya Fever

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorJiangsu Kanion Pharmaceutical Co., Ltd

About this trial

To evaluate the efficacy and safety of Reduning Injection in the treatment of chikungunya fever

Eligibility criteria

Qualifiers

Meet the diagnostic criteria for chikungunya fever (can be randomly selected based on suspected cases);

Fever duration ≤ 48 hours, and at the time of consultation, axillary temperature ≥ 38.0℃ (if antipyretic drugs have been taken, the axillary temperature must be ≥ 38.0℃ 4 hours or later after taking the drugs);

The first symptoms of chikungunya fever other than fever have a duration ≤ 72 hours;

At the time of consultation, have one or more of the following symptoms: headache, back pain or generalized muscle pain, nausea and vomiting, joint pain, joint swelling, joint stiffness, rash, and the severity is moderate or above;

Disqualifiers

Those diagnosed with dengue fever, alphavirus infection, influenza, novel coronavirus infection, infectious erythema, post-infection arthritis (including rheumatic fever), scarlet fever, rickettsial diseases (typhus, scrub typhus), measles, drug-induced rash, etc.;

Acute, chronic stages of chikungunya fever and high-risk populations;

Those with severe primary diseases of the cardiovascular, liver, kidney and hematopoietic systems;

Those with chronic arthritis;

Trial design

Treatments tested in this trial

  • Reduning injection
  • The simulant of Reduning Injection

Treatment groups

400 Participants
are divided into 2 treatment groups