A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21+
SponsorMedical University of South Carolina

About this trial

This is a research study to find out if treatment decision making can be improved for smokers who find it difficult to quit with medications. Everyone who participates in this study will receive free product, either nicotine replacement therapies (patches and lozenges), varenicline, or a harm reduction product (e-cigarette) for a full 12 weeks. Most participants will receive some combination of these treatments, depending on individual response to each.

All visits and study assessments will be entirely remote. All treatments will be provided free of charge for the first 12 weeks. After that, the study team will contact the participants 6 months after the first study phone call to complete another survey. The study lasts six months and will involve 8 surveys.

Eligibility criteria

Qualifiers

Smokers who want to quit

Disqualifiers

Non-smokers

Trial design

Treatments tested in this trial

  • Switching to a different medication
  • Continued use of the same medication
  • Switching to a harm reduction tobacco product

Treatment groups

544 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Medical University of South Carolina

Lead sponsor

National Cancer Institute (NCI)

Collaborator