A Comprehensive Assessment of Altered Embodiment in Individuals With Spinal Cord Injury

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorSwiss Paraplegic Research, Nottwil

About this trial

Spinal cord injury (SCI) occurs when trauma or other factors damage the spinal cord, disrupting the flow of sensory information from the body to the brain. This interruption can interfere with embodiment-the body awareness and physical sensations processed by the brain-sometimes leading to a phenomenon called disembodiment.

For people with SCI, disembodiment may appear as unusual body sensations, like feeling that a limb is in a different position than it actually is. Such changes in body awareness can impact daily life, mental health, and rehabilitation outcomes.

Despite its importance, the study of embodiment in SCI remains limited. This project aims to explore how SCI alters embodiment, focusing on its specific characteristics, the effects on daily life, and the underlying brain activity as measured by functional magnetic resonance imaging (fMRI). Both people with and without SCI will participate.

Procedure: Participants will complete a single examination lasting 2 to 2.5 hours, including approximately 55 minutes in the MRI scanner (with preparation and follow-up).

Eligibility criteria

Qualifiers

Age between 18 and 60

Normal or corrected-to-normal visual acuity

German or Italian native speaker

Diagnosis of traumatic spinal cord injury

Disqualifiers

Pregnancy or breastfeeding

Diagnosis of other psychiatric or neurological disorders (e.g. epilepsy, tumor in the central nervous system)

Confirmed diagnosis of alcohol and/or drug abuse with active consumption within the last 6 months

Confirmed diagnosis of traumatic brain injury, intended as visible changes in the brain diagnosed by a radiologist

Trial design

Treatments tested in this trial

  • Behavioral assessment
  • Functional Magnetic Resonance Imaging (fMRI)

Treatment groups

80 Participants
are divided into 4 treatment groups