A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorYale University

About this trial

This study seeks to develop and test a novel digital pill system (DPS) that measures real-time medication ingestion and pairs it with a cognitive behavioral therapy (CBT)-based intervention to provide personalized, data-driven adherence support, with the long-term goal of providing new and improved personalized support and increase medication adherence for people with AUD and ALD.

Eligibility criteria

Qualifiers

Being treated for AUD

Diagnosed with DSM-5 moderate to severe AUD

Screens positive ALD utilizing non-invasive blood tests

Planned initiation of acamprosate

Disqualifiers

History of hypersensitivity to acamprosate

Allergy to magnesium or silver

Severe renal impairment (creatinine clearance of 30mL/min or less)

Trial design

Treatments tested in this trial

  • AcamproSync

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Yale University

Lead sponsor

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborator