About this trial
The purpose of this study is to evaluate the clinical benefits of different types of total knee arthroplasty (TKA) in osteoarthritis treatment. The study aims to compare surgical outcomes, functional recovery, complication rates, and cost-effectiveness among personalized, semi-personalized, and conventional TKA in a multi-center, bidirectional cohort study.
Eligibility criteria
Qualifiers
Patients aged 50-80 years.
Diagnosed with end-stage knee osteoarthritis, post-traumatic arthritis, avascular necrosis, or inflammatory arthritis requiring total knee arthroplasty.
Willing and able to provide informed consent.
Disqualifiers
History of prior knee surgery or knee replacement.
Severe knee deformity (valgus >20° or varus >15°) or instability.
Severe contracture (>25° flexion contracture).
Undergoing total knee revision surgery.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Beijing Tsinghua Chang Gung Hospital
Lead sponsor
Peking University Shougang Hospital
Collaborator
Beijing Chao Yang Hospital
Collaborator