A Multi-Center Bidirectional Cohort Study on Total Knee Arthroplasty for the Treatment of Knee Osteoarthritis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-80
SponsorBeijing Tsinghua Chang Gung Hospital

About this trial

The purpose of this study is to evaluate the clinical benefits of different types of total knee arthroplasty (TKA) in osteoarthritis treatment. The study aims to compare surgical outcomes, functional recovery, complication rates, and cost-effectiveness among personalized, semi-personalized, and conventional TKA in a multi-center, bidirectional cohort study.

Eligibility criteria

Qualifiers

Patients aged 50-80 years.

Diagnosed with end-stage knee osteoarthritis, post-traumatic arthritis, avascular necrosis, or inflammatory arthritis requiring total knee arthroplasty.

Willing and able to provide informed consent.

Disqualifiers

History of prior knee surgery or knee replacement.

Severe knee deformity (valgus >20° or varus >15°) or instability.

Severe contracture (>25° flexion contracture).

Undergoing total knee revision surgery.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

120 Participants
are grouped into 1 trial group

Sponsors and collaborators

Beijing Tsinghua Chang Gung Hospital

Lead sponsor

Peking University Shougang Hospital

Collaborator

Beijing Chao Yang Hospital

Collaborator