A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients.

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorGe Junbo

About this trial

The coronary angiography-derived index of microcirculatory resistance (caIMR) can be used to provide a binary assessment whether patients(with stable angina, unstable angina, suspected myocardial ischemia, or coronary artery stenosis of less than 50%, and without cardiomyopathy or obstructive epicardial coronary artery disease) have microcirculatory dysfunction, using a cutoff value of 25.

This study aims to evaluate the binary classification performance of caIMR in two specific groups of patients: (1) those with caIMR values between 20 and 30, and (2) those with diffuse disease. We will do this by looking at differences in their Seattle Angina Questionnaire (SAQ) scores and their health outcomes over a three-year period.

Eligibility criteria

Qualifiers

Age between 18 and 80 years, regardless of gender;

Diagnosed with stable angina, unstable angina, or suspected myocardial ischemia;

targeted vessel stenosis < 50% and caIMR values between 20 and 30; or

Disqualifiers

Previously undergone percutaneous coronary intervention (PCI);

History of heart failure or myocardial infarction;

Acute myocardial infarction;

Primary or secondary cardiomyopathy;

Trial design

Treatments tested in this trial

  • caIMR

Treatment groups

508 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Ge Junbo

Lead sponsor

Fudan University

Sponsor institution

RainMed Medical Group

Collaborator