A New Model to Induce Itch and Inflammation
ConditionItching
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAalborg University
About this trial
This project aims to create a reliable, long-lasting itch model by synergistically combining thermal pre-conditioning with the application of histamine or cowhage.
Eligibility criteria
Qualifiers
Healthy men and women
18-60 years
Speak and understand English
Disqualifiers
Pregnancy or lactation
Drug addiction defined as any use of cannabis, opioids, or other addictive drugs
Previous or current history of neurological (e.g., neuropathy), immunological (e.g., asthma, immune deficiencies, arthritis), musculoskeletal (e.g., muscular pain in the upper extremities), cardiac disorder (e.g., stroke), or psychiatric diagnoses (e.g., depression, bipolar disorders, acute and chronic psychosis) that may affect the results
Current use of medications that may affect the trial, such as antihistamines, antipsychotics, painkillers, and systemic or topical steroids
Trial design
Treatments tested in this trial
- Cowhage (Mucuna Pruriens)
- Histamine
- Heat
Treatment groups
28 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov